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Extract from the Register of European Patents

EP About this file: EP2406394

EP2406394 - REAGENTS AND METHODS FOR PCR [Right-click to bookmark this link]
StatusNo opposition filed within time limit
Status updated on  14.11.2014
Database last updated on 25.09.2024
Most recent event   Tooltip22.06.2018Lapse of the patent in a contracting state
New state(s): MK		published on 25.07.2018  [2018/30]
Applicant(s)For all designated states
BRANDEIS UNIVERSITY
415 South Street
Waltham, MA 02254 / US
[2012/03]
Inventor(s)01 / WANGH, Lawrence, J.
20 Duffield Road
Auburndale, MA 02466 / US
02 / RICE, John
268 Common Street
Quincy, MA 02169 / US
03 / RICE, Nicholas
268 Common Street
Quincy, MA 02169 / US
04 / JIA, Yanwei
17 Prospect Street
Apartment 4
Waltham, MA 02543 / US
 [2012/03]
Representative(s)Chapman, Lee Phillip, et al
J A Kemp
14 South Square
Gray's Inn
London WC1R 5JJ / GB
[2014/28]
Former [2014/02]Ford, Hazel, et al
J A Kemp
14 South Square
Gray's Inn
London WC1R 5JJ / GB
Former [2012/03]Ford, Hazel, et al
J.A. Kemp & Co.
14 South Square
Gray's Inn
London WC1R 5JJ / GB
Application number, filing date10708682.911.03.2010
WO2010US27011
Priority number, dateUS20090202565P12.03.2009         Original published format: US 202565 P
[2012/03]
Filing languageEN
Procedural languageEN
PublicationType: A1 Application with search report
No.:WO2010105074
Date:16.09.2010
Language:EN
[2010/37]
Type: A1 Application with search report 
No.:EP2406394
Date:18.01.2012
Language:EN
The application published by WIPO in one of the EPO official languages on 16.09.2010 takes the place of the publication of the European patent application.
[2012/03]
Type: B1 Patent specification 
No.:EP2406394
Date:08.01.2014
Language:EN
[2014/02]
Search report(s)International search report - published on:EP16.09.2010
ClassificationIPC:C12Q1/68
[2012/03]
CPC:
C12Q1/6806 (EP,US); C12Q1/6853 (EP,US)
C-Set:
C12Q1/6806, C12Q2545/114, C12Q2531/107, C12Q2527/107 (EP,US);
C12Q1/6853, C12Q2545/114, C12Q2531/107, C12Q2527/107 (US,EP)
Designated contracting statesAT,   BE,   BG,   CH,   CY,   CZ,   DE,   DK,   EE,   ES,   FI,   FR,   GB,   GR,   HR,   HU,   IE,   IS,   IT,   LI,   LT,   LU,   LV,   MC,   MK,   MT,   NL,   NO,   PL,   PT,   RO,   SE,   SI,   SK,   SM,   TR [2012/03]
Extension statesALNot yet paid
BANot yet paid
MENot yet paid
RSNot yet paid
TitleGerman:REAGENTIEN UND VERFAHREN FÜR PCR[2012/03]
English:REAGENTS AND METHODS FOR PCR[2012/03]
French:RÉACTIFS ET PROCÉDÉS POUR PCR[2012/03]
Entry into regional phase23.09.2011National basic fee paid 
23.09.2011Designation fee(s) paid 
23.09.2011Examination fee paid 
Examination procedure23.09.2011Examination requested  [2012/03]
30.04.2012Amendment by applicant (claims and/or description)
17.07.2012Despatch of a communication from the examining division (Time limit: M06)
11.01.2013Reply to a communication from the examining division
07.02.2013Despatch of a communication from the examining division (Time limit: M04)
17.06.2013Reply to a communication from the examining division
24.07.2013Communication of intention to grant the patent
02.12.2013Fee for grant paid
02.12.2013Fee for publishing/printing paid
Divisional application(s)EP13195156.8  / EP2703501
The date of the Examining Division's first communication in respect of the earliest application for which a communication has been issued is  17.07.2012
Opposition(s)09.10.2014No opposition filed within time limit [2014/51]
Fees paidRenewal fee
14.03.2012Renewal fee patent year 03
27.03.2013Renewal fee patent year 04
Opt-out from the exclusive  Tooltip
competence of the Unified
Patent Court		 See the Register of the Unified Patent Court for opt-out data
Responsibility for the accuracy, completeness or quality of the data displayed under the link provided lies entirely with the Unified Patent Court.
Lapses during opposition  TooltipHU11.03.2010
AT08.01.2014
BE08.01.2014
BG08.01.2014
CY08.01.2014
CZ08.01.2014
DK08.01.2014
EE08.01.2014
ES08.01.2014
FI08.01.2014
HR08.01.2014
LT08.01.2014
LV08.01.2014
MC08.01.2014
MK08.01.2014
MT08.01.2014
NL08.01.2014
PL08.01.2014
RO08.01.2014
SI08.01.2014
SK08.01.2014
SM08.01.2014
TR08.01.2014
LU11.03.2014
NO08.04.2014
GR09.04.2014
IS08.05.2014
PT08.05.2014
[2018/30]
Former [2016/33]HU11.03.2010
AT08.01.2014
BE08.01.2014
BG08.01.2014
CY08.01.2014
CZ08.01.2014
DK08.01.2014
EE08.01.2014
ES08.01.2014
FI08.01.2014
HR08.01.2014
LT08.01.2014
LV08.01.2014
MC08.01.2014
MT08.01.2014
NL08.01.2014
PL08.01.2014
RO08.01.2014
SI08.01.2014
SK08.01.2014
SM08.01.2014
TR08.01.2014
LU11.03.2014
NO08.04.2014
GR09.04.2014
IS08.05.2014
PT08.05.2014
Former [2016/32]HU11.03.2010
AT08.01.2014
BE08.01.2014
BG08.01.2014
CY08.01.2014
CZ08.01.2014
DK08.01.2014
EE08.01.2014
ES08.01.2014
FI08.01.2014
HR08.01.2014
LT08.01.2014
LV08.01.2014
MC08.01.2014
MT08.01.2014
NL08.01.2014
PL08.01.2014
RO08.01.2014
SI08.01.2014
SK08.01.2014
SM08.01.2014
LU11.03.2014
NO08.04.2014
GR09.04.2014
IS08.05.2014
PT08.05.2014
Former [2016/28]AT08.01.2014
BE08.01.2014
BG08.01.2014
CY08.01.2014
CZ08.01.2014
DK08.01.2014
EE08.01.2014
ES08.01.2014
FI08.01.2014
HR08.01.2014
LT08.01.2014
LV08.01.2014
MC08.01.2014
MT08.01.2014
NL08.01.2014
PL08.01.2014
RO08.01.2014
SI08.01.2014
SK08.01.2014
SM08.01.2014
LU11.03.2014
NO08.04.2014
GR09.04.2014
IS08.05.2014
PT08.05.2014
Former [2016/27]AT08.01.2014
BE08.01.2014
CY08.01.2014
CZ08.01.2014
DK08.01.2014
EE08.01.2014
ES08.01.2014
FI08.01.2014
HR08.01.2014
LT08.01.2014
LV08.01.2014
MC08.01.2014
MT08.01.2014
NL08.01.2014
PL08.01.2014
RO08.01.2014
SI08.01.2014
SK08.01.2014
SM08.01.2014
LU11.03.2014
NO08.04.2014
IS08.05.2014
PT08.05.2014
Former [2016/22]AT08.01.2014
BE08.01.2014
CY08.01.2014
CZ08.01.2014
DK08.01.2014
EE08.01.2014
ES08.01.2014
FI08.01.2014
HR08.01.2014
LT08.01.2014
LV08.01.2014
MT08.01.2014
NL08.01.2014
PL08.01.2014
RO08.01.2014
SI08.01.2014
SK08.01.2014
SM08.01.2014
LU11.03.2014
NO08.04.2014
IS08.05.2014
PT08.05.2014
Former [2016/12]AT08.01.2014
BE08.01.2014
CY08.01.2014
CZ08.01.2014
DK08.01.2014
EE08.01.2014
ES08.01.2014
FI08.01.2014
HR08.01.2014
LT08.01.2014
LV08.01.2014
MT08.01.2014
NL08.01.2014
PL08.01.2014
RO08.01.2014
SI08.01.2014
SK08.01.2014
LU11.03.2014
NO08.04.2014
IS08.05.2014
PT08.05.2014
Former [2015/24]AT08.01.2014
BE08.01.2014
CY08.01.2014
CZ08.01.2014
DK08.01.2014
EE08.01.2014
ES08.01.2014
FI08.01.2014
HR08.01.2014
LT08.01.2014
LV08.01.2014
NL08.01.2014
PL08.01.2014
RO08.01.2014
SI08.01.2014
SK08.01.2014
LU11.03.2014
NO08.04.2014
IS08.05.2014
PT08.05.2014
Former [2014/50]AT08.01.2014
BE08.01.2014
CY08.01.2014
CZ08.01.2014
DK08.01.2014
EE08.01.2014
ES08.01.2014
FI08.01.2014
HR08.01.2014
LT08.01.2014
LV08.01.2014
NL08.01.2014
PL08.01.2014
RO08.01.2014
SK08.01.2014
LU11.03.2014
NO08.04.2014
IS08.05.2014
PT08.05.2014
Former [2014/49]AT08.01.2014
BE08.01.2014
CY08.01.2014
CZ08.01.2014
DK08.01.2014
EE08.01.2014
ES08.01.2014
FI08.01.2014
HR08.01.2014
LT08.01.2014
LV08.01.2014
NL08.01.2014
RO08.01.2014
LU11.03.2014
NO08.04.2014
IS08.05.2014
PT08.05.2014
Former [2014/48]AT08.01.2014
BE08.01.2014
CY08.01.2014
CZ08.01.2014
DK08.01.2014
EE08.01.2014
ES08.01.2014
FI08.01.2014
HR08.01.2014
LT08.01.2014
LV08.01.2014
NL08.01.2014
LU11.03.2014
NO08.04.2014
IS08.05.2014
PT08.05.2014
Former [2014/41]AT08.01.2014
BE08.01.2014
CY08.01.2014
ES08.01.2014
FI08.01.2014
HR08.01.2014
LT08.01.2014
LV08.01.2014
NL08.01.2014
NO08.04.2014
IS08.05.2014
PT08.05.2014
Former [2014/39]AT08.01.2014
CY08.01.2014
ES08.01.2014
FI08.01.2014
LT08.01.2014
NL08.01.2014
NO08.04.2014
IS08.05.2014
PT08.05.2014
Former [2014/37]AT08.01.2014
CY08.01.2014
ES08.01.2014
FI08.01.2014
LT08.01.2014
NO08.04.2014
IS08.05.2014
PT08.05.2014
Former [2014/36]LT08.01.2014
NO08.04.2014
IS08.05.2014
Cited inInternational search[X]WO2006044994  (UNIV BRANDEIS [US], et al) [X] 1-40 * pages 3-76; examples 2-4,16 *;
 [A]WO03054233  (UNIV BRANDEIS [US], et al) [A] 1-40 * the whole document *;
 [Y]  - KAINZ PETER ET AL, "Specificity-enhanced hot-start PCR: Addition of double-stranded DNA fragments adapted to the annealing temperature", BIOTECHNIQUES, INFORMA LIFE SCIENCES PUBLISHING, WESTBOROUGH, MA, US, (20000201), vol. 28, no. 2, ISSN 0736-6205, pages 278 - 282, XP002202181 [Y] 1-40 * the whole document *
 [Y]  - KABOEV O K ET AL, "PCR hot start using primers with the structure of molecular beacons (hairpin-like structure)", NUCLEIC ACIDS RESEARCH, OXFORD UNIVERSITY PRESS, SURREY, GB LNKD- DOI:10.1093/NAR/28.21.E94, (20001101), vol. 28, no. 21, ISSN 0305-1048, page E94, XP002244959 [Y] 1-40 * the whole document *

DOI:   http://dx.doi.org/10.1093/nar/28.21.e94
 [A]  - SANCHEZ J AQUILES ET AL, "Linear-After-The-Exponential (LATE)-PCR: An advanced method of asymmetric PCR and its uses in quantitative real-time analysis", PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES (PNAS), NATIONAL ACADEMY OF SCIENCE, US LNKD- DOI:10.1073/PNAS.0305476101, (20040217), vol. 101, no. 7, ISSN 0027-8424, pages 1933 - 1938, XP002492383 [A] 1-40 * the whole document *

DOI:   http://dx.doi.org/10.1073/pnas.0305476101
ExaminationWO2007008728
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by applicantUS4683202
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 US5066584
 WO03054233
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    - SANCHEZ ET AL., PNAS, (2004), vol. 101, pages 1933 - 1938
    - PIERCE ET AL., PNAS, (2005), vol. 102, pages 8609 - 8614
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    - Methods in Molecular Biology, HUMANA PRESS, pages 3 - 31
    - SANTA LUCIA, J., PNAS (USA), (1998), vol. 95, pages 1460 - 1465
    - ALLAWI, H. T.; SANTA LUCIA, J., BIOCHEM., (1997), vol. 36, pages 10581 - 10594
    - "LJNAFOLD: software for nucleic acid folding and hybridization", MARKHAM; ZUKER, BIOINFORMATICS, vol. II, Structure, Functions and Applications, No. 453 in Methods in Molecular Biology, HUMANA PRESS, (2008), vol. II, pages 3 - 31
    - RICE, J.E. ET AL., "Monoplex/Multiplex Linear-After-The-Exponential PCR Assay Combined with PrimeSafe and Dilute-'N'-Go Sequencing", NATURE PROTOCOLS, (2007), vol. 2, pages 2429 - 2438
    - NEWTON ET AL., "Analysis of any point mutation in DNA. The amplification refractory mutation system (ARMS)", NUCLEIC ACIDS RES., (1989), vol. 17, pages 2503 - 2516
 US20050242506
The EPO accepts no responsibility for the accuracy of data originating from other authorities; in particular, it does not guarantee that it is complete, up to date or fit for specific purposes.