blank Quick help
blank Maintenance news

Scheduled maintenance

Regular maintenance outages:
between 05.00 and 05.15 hrs CET (Monday to Sunday).

Other outages
Availability

2022.02.11

More...
blank News flashes

News Flashes

New version of the European Patent Register – SPC proceedings information in the Unitary Patent Register.

2024-07-24

More...
blank Related links

Release notes
European Patent Register Assistant
European Patent Register Resource Book
European Patent Register – pocket guide
FAQ - European Patent Register
Federated Register (Flyer)
Global Dossier (Flyer)
Register events
Deep link coverage
Federated Register content
The Patent Information Tour
Fair use charter

Extract from the Register of European Patents

EP About this file: EP2405896

EP2405896 - GLYCEROSOMES AND USE THEREOF IN PHARMACEUTICAL AND COSMETIC PREPARATIONS FOR TOPICAL APPLICATION [Right-click to bookmark this link]
StatusNo opposition filed within time limit
Status updated on  13.03.2015
Database last updated on 25.09.2024
Most recent event   Tooltip13.03.2020Change - lapse in a contracting state
State(s) deleted from list of lapses: TR		published on 15.04.2020  [2020/16]
Applicant(s)For all designated states
Prigen S.r.l.
Via Anita Garibaldi 1
20052 Monza (MI) / IT
[2012/03]
Inventor(s)01 / ZARU, Marco
c/o Prigen S.r.l.
Via Anita Garibaldi 1
I-20052 Monza (MI) / IT
02 / MANCA, Maria Letizia
c/o Prigen S.r.l.
Via Anita Garibaldi 1
I-20052 Monza (MI) / IT
03 / FADDA, Anna Maria
c/o Prigen S.r.l.
Via Anita Garibaldi 1
I-20052 Monza (MI) / IT
04 / ORSINI, Gaetano
c/o Prigen S.r.l.
Via Anita Garibaldi 1
I-20052 Monza (MI) / IT
 [2012/03]
Representative(s)Banfi, Paolo
Bianchetti & Minoja with
Trevisan & Cuonzo IPS Srl
Via Plinio, 63
20129 Milano / IT
[N/P]
Former [2012/03]Banfi, Paolo
Bianchetti Bracco Minoja S.r.l. Via Plinio, 63
20129 Milano / IT
Application number, filing date10711328.408.03.2010
WO2010EP01428
Priority number, dateIT2009MI0035010.03.2009         Original published format: IT MI20090350
[2012/03]
Filing languageEN
Procedural languageEN
PublicationType: A1 Application with search report
No.:WO2010102770
Date:16.09.2010
Language:EN
[2010/37]
Type: A1 Application with search report 
No.:EP2405896
Date:18.01.2012
Language:EN
The application published by WIPO in one of the EPO official languages on 16.09.2010 takes the place of the publication of the European patent application.
[2012/03]
Type: B1 Patent specification 
No.:EP2405896
Date:07.05.2014
Language:EN
[2014/19]
Search report(s)International search report - published on:EP16.09.2010
ClassificationIPC:A61K9/127
[2012/03]
CPC:
A61K9/127 (EP,US); A61P17/00 (EP); A61P17/06 (EP);
A61P17/18 (EP); A61P29/00 (EP); A61P3/02 (EP);
A61P31/10 (EP); A61P31/12 (EP) (-)
Designated contracting statesAT,   BE,   BG,   CH,   CY,   CZ,   DE,   DK,   EE,   ES,   FI,   FR,   GB,   GR,   HR,   HU,   IE,   IS,   IT,   LI,   LT,   LU,   LV,   MC,   MK,   MT,   NL,   NO,   PL,   PT,   RO,   SE,   SI,   SK,   SM,   TR [2012/03]
Extension statesALNot yet paid
BANot yet paid
MENot yet paid
RSNot yet paid
TitleGerman:GLYCEROSOMES UND IHRE VERWENDUNG IN PHARMAZEUTISCHEN UND KOSMETISCHEN ZUBEREITUNGEN ZUR TOPISCHEN VERABREICHUNG[2012/03]
English:GLYCEROSOMES AND USE THEREOF IN PHARMACEUTICAL AND COSMETIC PREPARATIONS FOR TOPICAL APPLICATION[2012/03]
French:GLYCÉROSOMES ET LEUR UTILISATION DANS DES PRÉPARATIONS PHARMACEUTIQUES ET COSMÉTIQUES POUR APPLICATION TOPIQUE[2012/03]
Entry into regional phase05.08.2011National basic fee paid 
05.08.2011Designation fee(s) paid 
05.08.2011Examination fee paid 
Examination procedure05.08.2011Examination requested  [2012/03]
05.04.2012Amendment by applicant (claims and/or description)
27.06.2013Despatch of a communication from the examining division (Time limit: M04)
23.10.2013Reply to a communication from the examining division
11.12.2013Communication of intention to grant the patent
04.03.2014Fee for grant paid
04.03.2014Fee for publishing/printing paid
Divisional application(s)The date of the Examining Division's first communication in respect of the earliest application for which a communication has been issued is  27.06.2013
Opposition(s)10.02.2015No opposition filed within time limit [2015/16]
Fees paidRenewal fee
26.03.2012Renewal fee patent year 03
27.03.2013Renewal fee patent year 04
28.03.2014Renewal fee patent year 05
Opt-out from the exclusive  Tooltip
competence of the Unified
Patent Court		 See the Register of the Unified Patent Court for opt-out data
Responsibility for the accuracy, completeness or quality of the data displayed under the link provided lies entirely with the Unified Patent Court.
Lapses during opposition  TooltipHU08.03.2010
AT07.05.2014
BE07.05.2014
BG07.05.2014
CY07.05.2014
CZ07.05.2014
DK07.05.2014
EE07.05.2014
FI07.05.2014
HR07.05.2014
IT07.05.2014
LT07.05.2014
LV07.05.2014
MC07.05.2014
MK07.05.2014
MT07.05.2014
NL07.05.2014
PL07.05.2014
RO07.05.2014
SE07.05.2014
SI07.05.2014
SK07.05.2014
SM07.05.2014
NO07.08.2014
GR08.08.2014
IS07.09.2014
PT08.09.2014
[2020/16]
Former [2020/15]HU08.03.2010
AT07.05.2014
BE07.05.2014
BG07.05.2014
CY07.05.2014
CZ07.05.2014
DK07.05.2014
EE07.05.2014
FI07.05.2014
HR07.05.2014
IT07.05.2014
LT07.05.2014
LV07.05.2014
MC07.05.2014
MK07.05.2014
MT07.05.2014
NL07.05.2014
PL07.05.2014
RO07.05.2014
SE07.05.2014
SI07.05.2014
SK07.05.2014
SM07.05.2014
TR07.05.2014
NO07.08.2014
GR08.08.2014
IS07.09.2014
PT08.09.2014
Former [2018/30]HU08.03.2010
AT07.05.2014
BE07.05.2014
BG07.05.2014
CY07.05.2014
CZ07.05.2014
DK07.05.2014
EE07.05.2014
FI07.05.2014
HR07.05.2014
IT07.05.2014
LT07.05.2014
LV07.05.2014
MC07.05.2014
MK07.05.2014
MT07.05.2014
NL07.05.2014
PL07.05.2014
RO07.05.2014
SE07.05.2014
SI07.05.2014
SK07.05.2014
SM07.05.2014
NO07.08.2014
GR08.08.2014
IS07.09.2014
PT08.09.2014
Former [2017/38]HU08.03.2010
AT07.05.2014
BE07.05.2014
BG07.05.2014
CY07.05.2014
CZ07.05.2014
DK07.05.2014
EE07.05.2014
FI07.05.2014
HR07.05.2014
IT07.05.2014
LT07.05.2014
LV07.05.2014
MC07.05.2014
MT07.05.2014
NL07.05.2014
PL07.05.2014
RO07.05.2014
SE07.05.2014
SI07.05.2014
SK07.05.2014
SM07.05.2014
NO07.08.2014
GR08.08.2014
IS07.09.2014
PT08.09.2014
Former [2017/03]AT07.05.2014
BE07.05.2014
CY07.05.2014
CZ07.05.2014
DK07.05.2014
EE07.05.2014
FI07.05.2014
HR07.05.2014
IT07.05.2014
LT07.05.2014
LV07.05.2014
MC07.05.2014
MT07.05.2014
NL07.05.2014
PL07.05.2014
RO07.05.2014
SE07.05.2014
SI07.05.2014
SK07.05.2014
NO07.08.2014
GR08.08.2014
IS07.09.2014
PT08.09.2014
Former [2015/46]AT07.05.2014
BE07.05.2014
CY07.05.2014
CZ07.05.2014
DK07.05.2014
EE07.05.2014
FI07.05.2014
HR07.05.2014
IT07.05.2014
LT07.05.2014
LV07.05.2014
MC07.05.2014
NL07.05.2014
PL07.05.2014
RO07.05.2014
SE07.05.2014
SI07.05.2014
SK07.05.2014
NO07.08.2014
GR08.08.2014
IS07.09.2014
PT08.09.2014
Former [2015/36]AT07.05.2014
BE07.05.2014
CY07.05.2014
CZ07.05.2014
DK07.05.2014
EE07.05.2014
FI07.05.2014
HR07.05.2014
IT07.05.2014
LT07.05.2014
LV07.05.2014
NL07.05.2014
PL07.05.2014
RO07.05.2014
SE07.05.2014
SI07.05.2014
SK07.05.2014
NO07.08.2014
GR08.08.2014
IS07.09.2014
PT08.09.2014
Former [2015/22]AT07.05.2014
BE07.05.2014
CY07.05.2014
CZ07.05.2014
DK07.05.2014
EE07.05.2014
FI07.05.2014
HR07.05.2014
IT07.05.2014
LT07.05.2014
LV07.05.2014
NL07.05.2014
PL07.05.2014
RO07.05.2014
SE07.05.2014
SK07.05.2014
NO07.08.2014
GR08.08.2014
IS07.09.2014
PT08.09.2014
Former [2015/12]AT07.05.2014
BE07.05.2014
CY07.05.2014
CZ07.05.2014
DK07.05.2014
EE07.05.2014
FI07.05.2014
HR07.05.2014
LT07.05.2014
LV07.05.2014
NL07.05.2014
PL07.05.2014
RO07.05.2014
SE07.05.2014
SK07.05.2014
NO07.08.2014
GR08.08.2014
IS07.09.2014
PT08.09.2014
Former [2015/11]AT07.05.2014
BE07.05.2014
CY07.05.2014
CZ07.05.2014
DK07.05.2014
EE07.05.2014
FI07.05.2014
HR07.05.2014
LT07.05.2014
LV07.05.2014
PL07.05.2014
RO07.05.2014
SE07.05.2014
SK07.05.2014
NO07.08.2014
GR08.08.2014
IS07.09.2014
PT08.09.2014
Former [2015/10]AT07.05.2014
BE07.05.2014
CY07.05.2014
CZ07.05.2014
DK07.05.2014
EE07.05.2014
FI07.05.2014
HR07.05.2014
LT07.05.2014
LV07.05.2014
PL07.05.2014
SE07.05.2014
SK07.05.2014
NO07.08.2014
GR08.08.2014
IS07.09.2014
PT08.09.2014
Former [2015/08]AT07.05.2014
BE07.05.2014
CY07.05.2014
DK07.05.2014
FI07.05.2014
HR07.05.2014
LT07.05.2014
LV07.05.2014
PL07.05.2014
SE07.05.2014
NO07.08.2014
GR08.08.2014
IS07.09.2014
PT08.09.2014
Former [2015/02]AT07.05.2014
CY07.05.2014
FI07.05.2014
HR07.05.2014
LT07.05.2014
LV07.05.2014
PL07.05.2014
SE07.05.2014
NO07.08.2014
GR08.08.2014
IS07.09.2014
PT08.09.2014
Former [2014/51]AT07.05.2014
CY07.05.2014
FI07.05.2014
HR07.05.2014
LT07.05.2014
LV07.05.2014
PL07.05.2014
SE07.05.2014
NO07.08.2014
GR08.08.2014
IS07.09.2014
Former [2014/50]CY07.05.2014
FI07.05.2014
HR07.05.2014
LT07.05.2014
LV07.05.2014
PL07.05.2014
SE07.05.2014
NO07.08.2014
GR08.08.2014
IS07.09.2014
Former [2014/49]CY07.05.2014
FI07.05.2014
LT07.05.2014
NO07.08.2014
IS07.09.2014
Former [2014/48]CY07.05.2014
LT07.05.2014
Former [2014/47]CY07.05.2014
Cited inInternational search[X]WO9218103  (PHARES PHARMA HOLLAND [NL]) [X] 1-11 * page 12 - page 14; example 2 *;
 [XI]EP1013268  (ROHTO PHARMA [JP]) [X] 1,3-11 * column 8 - column 9; example 1 * [I] 2;
 [A]US2006099244  (GUILFORD F T [US]) [A] 1-11* page 5 - page 6; examples 2,3 *
ExaminationUS6348215
by applicantUS4235871
 WO9218103
 WO9218193
 US5716638
 EP1013268
 US2006099244
    - BANGHAM ET AL., "The action of steroids and streptolysin S on the permeability of phospholipid structures to cations", J. MOL. BIOL., (1965), vol. 13, pages 238 - 252
    - CEVC G; BLUME G, "Lipid vesicles penetrate into intact skin owing to the transdermal osmotic gradients and hydration force", BIOCHIM. BIOPHYS. ACTA, (1992), vol. 1104, pages 226 - 232
    - CEVC G; GEBAUER D, "Hydration-driven transport of deformable lipid vesicles through fine pores and skin barrier", BIOPHYS. J., (2003), vol. 84, pages 1010 - 1024
    - CEVC G., "Lipid vesicles and other colloids as drug carrier on the skin", ADV.DRUG DELIV.REV., (2004), vol. 56, pages 675 - 711
    - EL MAGHRABY G.M ET AL., "Can drug bearing liposomes penetrate intact skin?", J. PHARM. PHARMACOL., (2006), vol. 58, pages 415 - 429
    - ELSAYED MMA ET AL., "Deformable liposomes and ethosomes: Mechanism of enhanced skin delivery", INTERNATIONAL JOURNAL OF PHARMACEUTICS, (2006), vol. 322, pages 60 - 66
    - IMURA T, "Preparation and physicochemical properties of various soybean lecithin liposomes using supercritical reverse phase evaporation method", COLLOIDS AND SURFACE B : BIOINTERFACES., (2002), vol. 27, pages 133 - 140
    - KIRBY C; GREGORIADIS G, "Dehydration-rehydration vesicles (DRV): A new method for high yield drug entrapment in liposomes", BIOTECHNOLOGY, (1984), vol. 11, pages 979 - 984
    - LAVON I; KOST J, "Ultrasound and transdermal drug delivery", DRUG DISCOV. TODAY, (2004), vol. 9, pages 670 - 676
    - LICHTENBERG D; BARENHOLZ Y, "Liposomes: preparation, characterization and preservation", METH. BIOCHEM. ANAL., (1988), vol. 33, pages 337 - 461
    - MANOSROI A ET AL., "Characterization of vesicles prepared with various non ionic surfactants mixed with cholesterol", COLLOIDS AND SURFACE B: BIOINTERFACES, (2003), vol. 30, pages 129 - 138
    - MELE S ET AL., "Monolein based liquid crystals to form long-term stable emulsion", COLLOIDS AND SURFACE A PHYSICOCHEM ENG. ASPECTS, (2003), vol. 228, pages 57 - 63
    - MEZEI M; GULASEKHARAM V, "Liposomes-a selective drug delivery system for topical route of administration. 1. Lotion dosage form", PHARM. SCI., (1980), vol. 82, no. 1, pages 17 - 21
    - MEZEI M., Liposomes in topical application of drugs. Liposomes as Drugs Carriers : Recent Trends and Progress, WILEY J. & SONS, (1988), pages 663 - 677
    - PICK U., "Liposomes with a large trapping capacity prepared by freezing and thawing of sonicated phospholipid mixtures", ARCH. BIOCHEM. BIOPHYS., (1981), vol. 212, pages 186 - 194
    - SINICO C. ET AL., "Liposomal incorporation of Artemisia Arborescens L. essential oil and in vitro antiviral activity", EUR. J. PHARM. BIOPHARM., (2005), vol. 59, pages 161 - 168
    - SINICO C, "Liposomes as carriers for dermal delivery of tretinoin: in vitro evaluation of drug permeation and vesicles skin interaction", J. CONTR. REL, (2005), vol. 103, pages 123 - 126
    - MANCONI, "Niosomes as carriers for tretinoin III. A study into in vitro cutaneous delivery of vesicles-incorporated tretinoin", INT. J. PHARM., (2006), vol. 311, pages 11 - 19
    - SKOZA F; PAPAHADJOPOULOS D, "Comparative properties and methods of preparation of lipid vesicles (liposomes)", ANNU. REV. BIOPHYS. BIOENG., (1980), vol. 9, pages 467 - 508
    - TOUITOU E ET AL., "Ethosomes - novel vesicular carriers for enhanced delivery: characterization and skin penetration properties", J.CONTROL.REL., (2000), vol. 65, pages 403 - 418
    - VEMURI S; RHODES CT, "Preparation and characteration of liposomes as therapeutic delivery systems: a review", PHARM. ACTA HELV., (1995), vol. 70, pages 95 - 111
    - WILLIAMS AC; BARRY BW, "Skin absorption enhancers", CRIT. REV. THER. DRUG CARR. SYS., (1992), vol. 9, pages 305 - 53
    - WOODLE MC; PAPAHDJOPOULOS D, "Liposome preparation and size characterization", METH. ENZYMOL., (1989), vol. 171, pages 193 - 217
The EPO accepts no responsibility for the accuracy of data originating from other authorities; in particular, it does not guarantee that it is complete, up to date or fit for specific purposes.