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Extract from the Register of European Patents

EP About this file: EP2427456

EP2427456 - ISOXAZOLE-PYRIDINE DERIVATIVES [Right-click to bookmark this link]
StatusNo opposition filed within time limit
Status updated on  11.12.2020
Database last updated on 22.08.2024
FormerThe patent has been granted
Status updated on  03.01.2020
FormerGrant of patent is intended
Status updated on  05.09.2019
FormerExamination is in progress
Status updated on  11.11.2016
Most recent event   Tooltip08.07.2022Lapse of the patent in a contracting state
New state(s): MK		published on 10.08.2022  [2022/32]
Applicant(s)For all designated states
F. Hoffmann-La Roche AG
Grenzacherstrasse 124
4070 Basel / CH
[2020/06]
Former [2012/11]For all designated states
F.Hoffmann-La Roche AG
Grenzacherstrasse 124
4070 Basel / CH
Inventor(s)01 / JAKOB-ROETNE, Roland
Oberer Baselblick 37
79594 Inzlingen / DE
02 / LUCAS, Matthew, C.
41 Wayland Drive
Verona, New Jersey 07044 / US
03 / THOMAS, Andrew
Weinbergstrasse 29
CH-4102 Binningen / CH
 [2012/11]
Representative(s)Salud, Carlos E.
F. Hoffmann-La Roche AG
Grenzacherstrasse 124
4070 Basel / CH
[2020/06]
Former [2012/11]Salud, Carlos E.
F. Hoffmann-La Roche AG Grenzacherstrasse 124
4070 Basel / CH
Application number, filing date10715271.228.04.2010
[2020/06]
WO2010EP55695
Priority number, dateEP2009015945705.05.2009         Original published format: EP 09159457
[2012/11]
Filing languageEN
Procedural languageEN
PublicationType: A1 Application with search report
No.:WO2010127976
Date:11.11.2010
Language:EN
[2010/45]
Type: A1 Application with search report 
No.:EP2427456
Date:14.03.2012
Language:EN
The application published by WIPO in one of the EPO official languages on 11.11.2010 takes the place of the publication of the European patent application.
[2012/11]
Type: B1 Patent specification 
No.:EP2427456
Date:05.02.2020
Language:EN
[2020/06]
Search report(s)International search report - published on:EP11.11.2010
ClassificationIPC:C07D413/12, C07D413/14, C07D417/14, A61K31/4439, A61P25/28
[2012/11]
CPC:
C07D413/12 (EP,KR,US); A61K31/422 (KR); A61P21/00 (EP);
A61P25/00 (EP); A61P25/14 (EP); A61P25/18 (EP);
A61P25/20 (EP); A61P25/22 (EP); A61P25/24 (EP);
A61P25/28 (EP); A61P25/36 (EP); A61P9/00 (EP);
C07D413/14 (EP,KR,US); C07D417/14 (EP,US) (-)
Designated contracting statesAT,   BE,   BG,   CH,   CY,   CZ,   DE,   DK,   EE,   ES,   FI,   FR,   GB,   GR,   HR,   HU,   IE,   IS,   IT,   LI,   LT,   LU,   LV,   MC,   MK,   MT,   NL,   NO,   PL,   PT,   RO,   SE,   SI,   SK,   SM,   TR [2012/11]
Extension statesALNot yet paid
BANot yet paid
MENot yet paid
RSNot yet paid
TitleGerman:ISOXAZOL-PYRIDIN-DERIVATE[2019/37]
English:ISOXAZOLE-PYRIDINE DERIVATIVES[2012/11]
French:DERIVES D' ISOXAZOLE-PYRIDINE[2019/37]
Former [2012/11]ISOXAZOLPYRIDINDERIVATE
Former [2012/11]DÉRIVÉS D'ISOXAZOLE-PYRIDINE
Entry into regional phase05.12.2011National basic fee paid 
05.12.2011Designation fee(s) paid 
05.12.2011Examination fee paid 
Examination procedure05.12.2011Examination requested  [2012/11]
23.05.2012Amendment by applicant (claims and/or description)
14.11.2016Despatch of a communication from the examining division (Time limit: M06)
19.05.2017Reply to a communication from the examining division
29.05.2017Despatch of a communication from the examining division (Time limit: M06)
09.01.2018Despatch of communication that the application is deemed to be withdrawn, reason: reply to the communication from the examining division not received in time
27.02.2018Reply to a communication from the examining division
06.09.2019Communication of intention to grant the patent
17.12.2019Fee for grant paid
17.12.2019Fee for publishing/printing paid
17.12.2019Receipt of the translation of the claim(s)
Divisional application(s)The date of the Examining Division's first communication in respect of the earliest application for which a communication has been issued is  14.11.2016
Opposition(s)06.11.2020No opposition filed within time limit [2021/02]
Request for further processing for:The application is deemed to be withdrawn due to failure to reply to the examination report
27.02.2018Request for further processing filed
27.02.2018Full payment received (date of receipt of payment)
Request granted
08.03.2018Decision despatched
Fees paidRenewal fee
21.03.2012Renewal fee patent year 03
26.03.2013Renewal fee patent year 04
26.03.2014Renewal fee patent year 05
08.04.2015Renewal fee patent year 06
30.03.2016Renewal fee patent year 07
10.04.2017Renewal fee patent year 08
06.04.2018Renewal fee patent year 09
08.04.2019Renewal fee patent year 10
Opt-out from the exclusive  Tooltip
competence of the Unified
Patent Court		 See the Register of the Unified Patent Court for opt-out data
Responsibility for the accuracy, completeness or quality of the data displayed under the link provided lies entirely with the Unified Patent Court.
Lapses during opposition  TooltipHU28.04.2010
AT05.02.2020
CY05.02.2020
CZ05.02.2020
DK05.02.2020
EE05.02.2020
ES05.02.2020
FI05.02.2020
HR05.02.2020
IT05.02.2020
LT05.02.2020
LV05.02.2020
MC05.02.2020
MK05.02.2020
MT05.02.2020
NL05.02.2020
PL05.02.2020
RO05.02.2020
SE05.02.2020
SI05.02.2020
SK05.02.2020
SM05.02.2020
TR05.02.2020
IE28.04.2020
LU28.04.2020
BE30.04.2020
BG05.05.2020
NO05.05.2020
GR06.05.2020
IS05.06.2020
PT28.06.2020
[2022/32]
Former [2022/27]HU28.04.2010
AT05.02.2020
CY05.02.2020
CZ05.02.2020
DK05.02.2020
EE05.02.2020
ES05.02.2020
FI05.02.2020
HR05.02.2020
IT05.02.2020
LT05.02.2020
LV05.02.2020
MC05.02.2020
MT05.02.2020
NL05.02.2020
PL05.02.2020
RO05.02.2020
SE05.02.2020
SI05.02.2020
SK05.02.2020
SM05.02.2020
TR05.02.2020
IE28.04.2020
LU28.04.2020
BE30.04.2020
BG05.05.2020
NO05.05.2020
GR06.05.2020
IS05.06.2020
PT28.06.2020
Former [2022/26]AT05.02.2020
CZ05.02.2020
DK05.02.2020
EE05.02.2020
ES05.02.2020
FI05.02.2020
HR05.02.2020
IT05.02.2020
LT05.02.2020
LV05.02.2020
MC05.02.2020
NL05.02.2020
PL05.02.2020
RO05.02.2020
SE05.02.2020
SI05.02.2020
SK05.02.2020
SM05.02.2020
TR05.02.2020
IE28.04.2020
LU28.04.2020
BE30.04.2020
BG05.05.2020
NO05.05.2020
GR06.05.2020
IS05.06.2020
PT28.06.2020
Former [2021/20]AT05.02.2020
CZ05.02.2020
DK05.02.2020
EE05.02.2020
ES05.02.2020
FI05.02.2020
HR05.02.2020
IT05.02.2020
LT05.02.2020
LV05.02.2020
MC05.02.2020
NL05.02.2020
PL05.02.2020
RO05.02.2020
SE05.02.2020
SI05.02.2020
SK05.02.2020
SM05.02.2020
IE28.04.2020
LU28.04.2020
BE30.04.2020
BG05.05.2020
NO05.05.2020
GR06.05.2020
IS05.06.2020
PT28.06.2020
Former [2021/10]AT05.02.2020
CZ05.02.2020
DK05.02.2020
EE05.02.2020
ES05.02.2020
FI05.02.2020
HR05.02.2020
IT05.02.2020
LT05.02.2020
LV05.02.2020
MC05.02.2020
NL05.02.2020
PL05.02.2020
RO05.02.2020
SE05.02.2020
SI05.02.2020
SK05.02.2020
SM05.02.2020
LU28.04.2020
BE30.04.2020
BG05.05.2020
NO05.05.2020
GR06.05.2020
IS05.06.2020
PT28.06.2020
Former [2021/08]CZ05.02.2020
DK05.02.2020
EE05.02.2020
ES05.02.2020
FI05.02.2020
HR05.02.2020
LT05.02.2020
LV05.02.2020
MC05.02.2020
NL05.02.2020
RO05.02.2020
SE05.02.2020
SK05.02.2020
SM05.02.2020
LU28.04.2020
BG05.05.2020
NO05.05.2020
GR06.05.2020
IS05.06.2020
PT28.06.2020
Former [2020/52]CZ05.02.2020
DK05.02.2020
EE05.02.2020
ES05.02.2020
FI05.02.2020
HR05.02.2020
LT05.02.2020
LV05.02.2020
MC05.02.2020
NL05.02.2020
RO05.02.2020
SE05.02.2020
SK05.02.2020
SM05.02.2020
BG05.05.2020
NO05.05.2020
GR06.05.2020
IS05.06.2020
PT28.06.2020
Former [2020/50]CZ05.02.2020
DK05.02.2020
EE05.02.2020
ES05.02.2020
FI05.02.2020
HR05.02.2020
LT05.02.2020
LV05.02.2020
NL05.02.2020
RO05.02.2020
SE05.02.2020
SK05.02.2020
SM05.02.2020
BG05.05.2020
NO05.05.2020
GR06.05.2020
IS05.06.2020
PT28.06.2020
Former [2020/49]CZ05.02.2020
DK05.02.2020
ES05.02.2020
FI05.02.2020
HR05.02.2020
LT05.02.2020
LV05.02.2020
NL05.02.2020
RO05.02.2020
SE05.02.2020
SK05.02.2020
SM05.02.2020
BG05.05.2020
NO05.05.2020
GR06.05.2020
IS05.06.2020
PT28.06.2020
Former [2020/48]DK05.02.2020
ES05.02.2020
FI05.02.2020
HR05.02.2020
LT05.02.2020
LV05.02.2020
NL05.02.2020
RO05.02.2020
SE05.02.2020
SM05.02.2020
BG05.05.2020
NO05.05.2020
GR06.05.2020
IS05.06.2020
PT28.06.2020
Former [2020/47]DK05.02.2020
ES05.02.2020
FI05.02.2020
HR05.02.2020
LT05.02.2020
LV05.02.2020
NL05.02.2020
SE05.02.2020
BG05.05.2020
NO05.05.2020
GR06.05.2020
IS05.06.2020
PT28.06.2020
Former [2020/45]FI05.02.2020
HR05.02.2020
LV05.02.2020
NL05.02.2020
SE05.02.2020
BG05.05.2020
NO05.05.2020
GR06.05.2020
IS05.06.2020
PT28.06.2020
Former [2020/40]FI05.02.2020
HR05.02.2020
LV05.02.2020
SE05.02.2020
BG05.05.2020
NO05.05.2020
GR06.05.2020
IS05.06.2020
PT28.06.2020
Former [2020/39]FI05.02.2020
HR05.02.2020
LV05.02.2020
SE05.02.2020
BG05.05.2020
NO05.05.2020
GR06.05.2020
PT28.06.2020
Former [2020/38]FI05.02.2020
HR05.02.2020
LV05.02.2020
SE05.02.2020
NO05.05.2020
GR06.05.2020
PT28.06.2020
Former [2020/37]FI05.02.2020
HR05.02.2020
LV05.02.2020
SE05.02.2020
NO05.05.2020
PT28.06.2020
Former [2020/36]FI05.02.2020
NO05.05.2020
PT28.06.2020
Former [2020/35]FI05.02.2020
NO05.05.2020
Cited inInternational search[A]WO2007039389  (HOFFMANN LA ROCHE [CH], et al) [A] 1-25 * page 1; compound I * * page 2, line 9 - line 11 ** page 13; example 26; table . *
by applicant   - MCNAMARA; SKELTON, PSYCHOBIOLOGY, (1993), vol. 21, pages 101 - 108
    - CENTRAL NERVOUS SYSTEM, LIKE NEUROSCIENCE LETTS., (2005), vol. 381, pages 108 - 13
    - NEUROPSYCHOBIOLOGY, (2001), vol. 43, no. 3, pages 141 - 44
    - AMER. J. MED. GENETICS, (2004), vol. 131B, pages 51 - 9
    - AUTISM, (2007), vol. 11, no. 2, pages 135 - 47
    - INVESTIGACION CLINICA, (2007), vol. 48, pages 529 - 41
    - NATURE NEUROSCIENCE, (2007), vol. 10, pages 411 - 13
    - NEUROSCIENCE LETTS., (2008), vol. 433, pages 22 - 7
    - CELL, (2008), vol. 135, pages 549 - 60
The EPO accepts no responsibility for the accuracy of data originating from other authorities; in particular, it does not guarantee that it is complete, up to date or fit for specific purposes.