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Extract from the Register of European Patents

EP About this file: EP2432883

EP2432883 - EUKARYOTIC HOST CELL COMPRISING AN EXPRESSION ENHANCER [Right-click to bookmark this link]
StatusThe application is deemed to be withdrawn
Status updated on  16.09.2016
Database last updated on 05.10.2024
Most recent event   Tooltip16.09.2016Application deemed to be withdrawnpublished on 19.10.2016  [2016/42]
Applicant(s)For all designated states
FH Campus Wien
Favoritenstrasse 226
1100 Vienna / AT
[2012/13]
Inventor(s)01 / STADLMAYR, Gerhard
Sonnleithnerg. 17/4/23
A-1100 Vienna / AT
02 / MATTANOVICH, Diethard
Ignazg. 7/3
A-1120 Vienna / AT
03 / SAUER, Michael
Blechturmg. 28/12
A-1040 Vienna / AT
 [2012/13]
Representative(s)Redl, Gerda, et al
REDL Life Science Patent Attorneys
Donau-City-Strasse 11
1220 Wien / AT
[N/P]
Former [2012/13]Redl, Gerda, et al
REDL Life Science Patent Attorneys Tech Gate Vienna Donau-City-Strasse 1
1220 Vienna / AT
Application number, filing date10723065.820.05.2010
WO2010EP56967
Priority number, dateEP2009016075020.05.2009         Original published format: EP 09160750
[2012/13]
Filing languageEN
Procedural languageEN
PublicationType: A2 Application without search report
No.:WO2010133668
Date:25.11.2010
Language:EN
[2010/47]
Type: A2 Application without search report 
No.:EP2432883
Date:28.03.2012
Language:EN
The application published by WIPO in one of the EPO official languages on 25.11.2010 takes the place of the publication of the European patent application.
[2012/13]
Search report(s)International search report - published on:EP13.01.2011
ClassificationIPC:C12N15/67
[2012/13]
CPC:
C12N15/815 (EP,US); C12N1/18 (KR); C12N15/67 (KR);
C12N15/81 (KR); C12N5/10 (KR)
Designated contracting statesAL,   AT,   BE,   BG,   CH,   CY,   CZ,   DE,   DK,   EE,   ES,   FI,   FR,   GB,   GR,   HR,   HU,   IE,   IS,   IT,   LI,   LT,   LU,   LV,   MC,   MK,   MT,   NL,   NO,   PL,   PT,   RO,   SE,   SI,   SK,   SM,   TR [2012/13]
TitleGerman:EUKARYONTISCHE WIRTSZELLE MIT EINEM EXPRESSIONSVERBESSERER[2012/13]
English:EUKARYOTIC HOST CELL COMPRISING AN EXPRESSION ENHANCER[2012/13]
French:CELLULE HÔTE EUCARYOTE COMPRENANT UN ACTIVATEUR D'EXPRESSION[2012/13]
Entry into regional phase08.11.2011National basic fee paid 
08.11.2011Designation fee(s) paid 
08.11.2011Examination fee paid 
Examination proceduredeletedCommunication of intention to grant the patent
08.11.2011Examination requested  [2012/13]
28.06.2012Amendment by applicant (claims and/or description)
25.02.2016Despatch of a communication from the examining division (Time limit: M02)
07.05.2016Application deemed to be withdrawn, date of legal effect  [2016/42]
03.06.2016Despatch of communication that the application is deemed to be withdrawn, reason: reply to the communication from the examining division not received in time  [2016/42]
Divisional application(s)The date of the Examining Division's first communication in respect of the earliest application for which a communication has been issued is  25.02.2016
Fees paidRenewal fee
22.05.2012Renewal fee patent year 03
27.05.2013Renewal fee patent year 04
26.05.2014Renewal fee patent year 05
20.03.2015Renewal fee patent year 06
Penalty fee
Additional fee for renewal fee
31.05.201607   M06   Not yet paid
Opt-out from the exclusive  Tooltip
competence of the Unified
Patent Court		 See the Register of the Unified Patent Court for opt-out data
Responsibility for the accuracy, completeness or quality of the data displayed under the link provided lies entirely with the Unified Patent Court.
Cited inInternational search[X]  - GASSER BRIGITTE ET AL, "Transcriptomics-based identification of novel factors enhancing heterologous protein secretion in Yeasts", APPLIED AND ENVIRONMENTAL MICROBIOLOGY, AMERICAN SOCIETY FOR MICROBIOLOGY, US, (20071001), vol. 73, no. 20, ISSN 0099-2240, pages 6499 - 6507, XP002499993 [X] 1-16 *Whole document*

DOI:   http://dx.doi.org/10.1128/AEM.01196-07
 [AD]  - PORRO DANILO ET AL, "Recombinant protein production in yeasts", MOLECULAR BIOTECHNOLOGY, (200511), vol. 31, no. 3, ISSN 1073-6085, pages 245 - 259, XP002557596 [AD] 1-16 *Whole document*

DOI:   http://dx.doi.org/10.1385/MB:31:3:245
 [A]  - DALY R ET AL, "EXPRESSION OF HETEROLOGOUS PROTEINS IN PICHIA PASTORIS: A USEFUL EXPERIMENTAL TOOL IN PROTEIN ENGINEERING AND PRODUCTION", JOURNAL OF MOLECULAR RECOGNITION, HEYDEN & SON LTD., LONDON, GB, (20050301), vol. 18, no. 2, ISSN 0952-3499, pages 119 - 138, XP009059265 [A] 1-16 *Whole document*

DOI:   http://dx.doi.org/10.1002/jmr.687
by applicantWO2008128701
 WO9325676
 WO9408012
 WO03057897
 WO2005067818
 WO2006067511
 WO0172783
    - WENTZ; SHUSTA, APPL. ENVIRON. MICROBIOL., (2007), vol. 73, no. 4, pages 1189 - 1198
    - ARCHER, D.; JEENES, D.; MACKENZIE, D., "Strategies for improving heterologous protein production from filamentous fungi", ANTONIE VAN LEEUWENHOEK, (1994), vol. 65, doi:doi:10.1007/BF00871952, pages 245 - 50, XP000943720

DOI:   http://dx.doi.org/10.1007/BF00871952
    - GETHING, M.; SAMBROOK, J., "Protein folding in the cell", NATURE, (1992), vol. 355, doi:doi:10.1038/355033a0, pages 33 - 45, XP002060491

DOI:   http://dx.doi.org/10.1038/355033a0
    - HOHENBLUM, H. ET AL., "Assessing viability and cell-associated product of recombinant protein producing Pichia pastoris with flow cytometry", J BIOTECHNOL, (2003), vol. 102, pages 281 - 290
    - KURTZMAN CP., "Description of Komagataella phaffii sp. nov. and the transfer of Pichia pseudopastoris to the methylotrophic yeast genus Komagataella", INT J SYST EVOL MICROBIOL, (2005), vol. 55, pages 973 - 976, XP002610732
    - LANG, C.; LOOMAN, A., "Efficient expression and secretion of Aspergillus niger RH5344 polygalacturonase in Saccharomyces cerevisiae", APPL MICROBIOL BIOTECHNOL, (1995), vol. 44, pages 147 - 56, XP001005274
    - MACAULEY-PATRICK, S.; FAZENDA, M. L.; MCNEIL, B.; HARVEY, L. M., "Heterologous protein production using the Pichia pastoris expression system", YEAST, (2005), vol. 22, doi:doi:10.1002/yea.1208, pages 249 - 70, XP002474659

DOI:   http://dx.doi.org/10.1002/yea.1208
    - MATTANOVICH, D.; GASSER, B.; HOHENBLUM, H.; SAUER, M., "Stress in recombinant protein producing yeasts", J BIOTECHNOL, (2004), vol. 113, doi:doi:10.1016/j.jbiotec.2004.04.035, pages 121 - 35, XP004569604

DOI:   http://dx.doi.org/10.1016/j.jbiotec.2004.04.035
    - MORI, K.; OGAWA, N.; KAWAHARA, T.; YANAGI, H.; YURA, T., "mRNA splicing-mediated C-terminal replacement of transcription factor Hac1 p is required for efficient activation of the unfolded protein response", PROC NATL ACAD SCI U S A, (2000), vol. 97, pages 4660 - 5
    - PORRO, D.; SAUER, M.; BRANDUARDI, P.; MATTANOVICH, D., "Recombinant protein production in yeasts", MOL BIOTECHNOL, (2005), vol. 31, pages 245 - 59
    - PUNT, P. J.; VAN BIEZEN, N.; CONESA, A.; ALBERS, A.; MANGNUS, J.; HONDEL, C., "Filamentous fungi as cell factories for heterologous protein production", TRENDS BIOTECHNOL, (2002), vol. 20, doi:doi:10.1016/S0167-7799(02)01933-9, pages 200 - 6, XP004349665

DOI:   http://dx.doi.org/10.1016/S0167-7799(02)01933-9
    - SAUER, M.; BRANDUARDI, P.; GASSER, B.; VALLI, M.; MAURER, M.; PORRO, D.; MATTANOVICH, D., "Differential gene expression in recombinant Pichia pastoris analysed by heterologous DNA microarray hybridisation", MICROB CELL FACT, (2004), vol. 3, doi:doi:10.1186/1475-2859-3-17, page 17, XP021007190

DOI:   http://dx.doi.org/10.1186/1475-2859-3-17
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DOI:   http://dx.doi.org/10.1016/0958-1669(91)90035-4
    - LONGTINE, M. S.; A. MCKENZIE, 3RD; D. J. DEMARINI; N. G. SHAH; A. WACH ET AL., "Additional modules for versatile and economical PCR-based gene deletion and modification in Saccharomyces cerevisiae", YEAST, (1998), vol. 14, doi:doi:10.1002/(SICI)1097-0061(199807)14:10<953::AID-YEA293>3.0.CO;2-U, pages 953 - 961, XP002668011

DOI:   http://dx.doi.org/10.1002/(SICI)1097-0061(199807)14:10<953::AID-YEA293>3.0.CO;2-U
    - HOHENBLUM H; GASSER B; MAURER M; BORTH N; MATTANOVICH D, "Effects of Gene Dosage, Promoters, and Substrates on Unfolded Protein Stress of Recombinant Pichia pastoris", BIOTECHNOL BIOENG, (20040220), vol. 85, no. 4, doi:doi:10.1002/bit.10904, pages 367 - 75, XP009118820

DOI:   http://dx.doi.org/10.1002/bit.10904
    - GASSER, B.; MAURER, M.; GACH, J.; KUNERT, R.; MATTANOVICH, D., "Engineering of Pichia pastoris for improved production of antibody fragments", BIOTECHNOL BIOENG, (2006), vol. 94, doi:doi:10.1002/bit.20851, pages 353 - 61, XP008101654

DOI:   http://dx.doi.org/10.1002/bit.20851
The EPO accepts no responsibility for the accuracy of data originating from other authorities; in particular, it does not guarantee that it is complete, up to date or fit for specific purposes.