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Extract from the Register of European Patents

EP About this file: EP2467399

EP2467399 - Purification of vWF for increased removal of non-lipid enveloped viruses [Right-click to bookmark this link]
Former [2012/26]PURIFICATION OF VWF FOR INCREASED REMOVAL OF NON-LIPID ENVELOPED VIRUSES
[2015/19]
StatusPatent maintained as amended
Status updated on  30.12.2022
Database last updated on 24.08.2024
Most recent event   Tooltip02.08.2024Lapse of the patent in a contracting state
New state(s): PL
published on 04.09.2024 [2024/36]
Applicant(s)For all designated states
Baxalta Incorporated
1200 Lakeside Drive
Bannockburn, IL 60015 / US
For all designated states
Baxalta GmbH
Zaehlerweg 4
6300 Zug / CH
[2023/04]
Former [2015/43]For all designated states
Baxalta Incorporated
1200 Lakeside Drive
Bannockburn, IL 60015 / US
For all designated states
Baxalta GmbH
Thurgauerstrasse 130
8152 Glattpark, Opfikon / CH
Former [2012/26]For all designated states
Baxter International Inc.
One Baxter Parkway
Deerfield, IL 60015 / US
For all designated states
Baxter Healthcare S.A.
Thurgauerstrasse 130
8152 Glattpark (Opfikon) / CH
Inventor(s)01 / MITTERER, Artur
Schwarzeckerweg 10
A-2304 Orth/Donau / AT
02 / HASSLACHER, Meinhard
Vorgartenstrasse 221/1/7
A-1020 Vienna / AT
03 / MAYER, Christa
Bahnhofstrasse 2
A-2412 Wolfsthal / AT
 [2012/26]
Representative(s)Alt, Michael, et al
Bird & Bird LLP
Maximiliansplatz 22
80333 München / DE
[2015/46]
Former [2012/26]Alt, Michael, et al
Bird & Bird LLP Pacellistraße 14
80333 München / DE
Application number, filing date10747134.420.08.2010
[2015/46]
WO2010US46180
Priority number, dateUS20090235570P20.08.2009         Original published format: US 235570 P
[2012/26]
Filing languageEN
Procedural languageEN
PublicationType: A1 Application with search report
No.:WO2011022657
Date:24.02.2011
Language:EN
[2011/08]
Type: A1 Application with search report 
No.:EP2467399
Date:27.06.2012
Language:EN
The application published by WIPO in one of the EPO official languages on 24.02.2011 takes the place of the publication of the European patent application.
[2012/26]
Type: B1 Patent specification 
No.:EP2467399
Date:11.11.2015
Language:EN
[2015/46]
Type: B2 New European patent specification 
No.:EP2467399
Date:01.02.2023
Language:EN
[2023/05]
Search report(s)International search report - published on:EP24.02.2011
ClassificationIPC:C07K14/755
[2015/23]
CPC:
C07K14/755 (EP,CN,US); A61K38/00 (EP,US); C07K1/18 (US)
Former IPC [2012/26]C07K14/755, A61K38/36
Designated contracting statesAL,   AT,   BE,   BG,   CH,   CY,   CZ,   DE,   DK,   EE,   ES,   FI,   FR,   GB,   GR,   HR,   HU,   IE,   IS,   IT,   LI,   LT,   LU,   LV,   MC,   MK,   MT,   NL,   NO,   PL,   PT,   RO,   SE,   SI,   SK,   SM,   TR [2012/26]
TitleGerman:Aufreinigung von vWF für erhöhte Entfernung von nichtlipiden eingehüllten Viren[2023/04]
English:Purification of vWF for increased removal of non-lipid enveloped viruses[2015/19]
French:Purification du vWF pour une meilleure élimination des virus à enveloppe non lipidique[2015/19]
Former [2012/26]AUFRENIGUNG VON VWF FÜR ERHÖHTE ENTFERNUNG VON NICHTLIPIDEN EINGEHÜLLTEN VIREN
Former [2012/26]PURIFICATION OF VWF FOR INCREASED REMOVAL OF NON-LIPID ENVELOPED VIRUSES
Former [2012/26]PURIFICATION DU VWF POUR UNE MEILLEURE ÉLIMINATION DES VIRUS À ENVELOPPE NON LIPIDIQUE
Entry into regional phase15.03.2012National basic fee paid 
15.03.2012Designation fee(s) paid 
15.03.2012Examination fee paid 
Examination procedure15.03.2012Examination requested  [2012/26]
22.10.2012Amendment by applicant (claims and/or description)
11.02.2013Despatch of a communication from the examining division (Time limit: M06)
20.08.2013Reply to a communication from the examining division
11.08.2014Despatch of a communication from the examining division (Time limit: M04)
17.12.2014Reply to a communication from the examining division
15.05.2015Communication of intention to grant the patent
23.09.2015Disapproval of the communication of intention to grant the patent by the applicant or resumption of examination proceedings by the EPO
23.09.2015Fee for grant paid
23.09.2015Fee for publishing/printing paid
05.10.2015Information about intention to grant a patent
05.10.2015Receipt of the translation of the claim(s)
Divisional application(s)The date of the Examining Division's first communication in respect of the earliest application for which a communication has been issued is  11.02.2013
Opposition(s)Opponent(s)01  11.08.2016  17.08.2016  ADMISSIBLE
Strawman Limited
Orchard Lea
Horns Lane
Combe, Witney
Oxfordshire OX29 8NH / GB
Opponent's representative
D Young & Co LLP
3 Noble Street
London EC2V 7BQ / GB
 [N/P]
Former [2016/38]
Opponent(s)01  11.08.2016  17.08.2016  ADMISSIBLE
Strawman Limited
Orchard Lea
Horns Lane
Combe, Witney
Oxfordshire OX29 8NH / GB
Opponent's representative
D Young & Co LLP
120 Holborn
London EC1N 2DY / GB
28.09.2016Invitation to proprietor to file observations on the notice of opposition
01.02.2017Reply of patent proprietor to notice(s) of opposition
13.02.2018Date of oral proceedings
09.07.2018Despatch of minutes of oral proceedings
11.07.2018Despatch of interlocutory decision in opposition
15.06.2021Legal effect of interlocutory decision in opposition
20.09.2022Despatch of communication that the patent will be maintained as amended
20.12.2022Fee for printing new specification paid
Appeal following opposition17.09.2018Appeal received No.  T2437/18
15.06.2021Result of appeal procedure: appeal of the proprietor was rejected
20.07.2022Despatch of the decision of the Board of Appeal
15.06.2021Date of oral proceedings
Fees paidRenewal fee
27.08.2012Renewal fee patent year 03
27.08.2013Renewal fee patent year 04
27.08.2014Renewal fee patent year 05
27.08.2015Renewal fee patent year 06
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See the Register of the Unified Patent Court for opt-out data
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Lapses during opposition  TooltipAL11.11.2015
BG11.11.2015
CY11.11.2015
CZ11.11.2015
EE11.11.2015
HR11.11.2015
LT11.11.2015
LV11.11.2015
MC11.11.2015
MK11.11.2015
PL11.11.2015
RO11.11.2015
SI11.11.2015
SK11.11.2015
SM11.11.2015
GR12.02.2016
IS11.03.2016
LU20.08.2016
MT31.08.2016
[2024/36]
Former [2023/35]AL11.11.2015
BG11.11.2015
CY11.11.2015
CZ11.11.2015
EE11.11.2015
HR11.11.2015
LT11.11.2015
LV11.11.2015
MC11.11.2015
MK11.11.2015
RO11.11.2015
SI11.11.2015
SK11.11.2015
SM11.11.2015
GR12.02.2016
IS11.03.2016
LU20.08.2016
MT31.08.2016
Former [2018/46]AL11.11.2015
BG11.11.2015
CY11.11.2015
EE11.11.2015
HR11.11.2015
LT11.11.2015
LV11.11.2015
MC11.11.2015
MK11.11.2015
RO11.11.2015
SI11.11.2015
SK11.11.2015
SM11.11.2015
GR12.02.2016
IS11.03.2016
LU20.08.2016
MT31.08.2016
Former [2018/38]BG11.11.2015
CY11.11.2015
EE11.11.2015
HR11.11.2015
LT11.11.2015
LV11.11.2015
MC11.11.2015
MK11.11.2015
RO11.11.2015
SI11.11.2015
SK11.11.2015
SM11.11.2015
GR12.02.2016
IS11.03.2016
LU20.08.2016
MT31.08.2016
Former [2018/34]CY11.11.2015
EE11.11.2015
HR11.11.2015
LT11.11.2015
LV11.11.2015
MC11.11.2015
MK11.11.2015
RO11.11.2015
SI11.11.2015
SK11.11.2015
SM11.11.2015
GR12.02.2016
IS11.03.2016
LU20.08.2016
MT31.08.2016
Former [2018/29]CY11.11.2015
EE11.11.2015
HR11.11.2015
LT11.11.2015
LV11.11.2015
MC11.11.2015
MK11.11.2015
RO11.11.2015
SI11.11.2015
SK11.11.2015
SM11.11.2015
GR12.02.2016
IS11.03.2016
LU20.08.2016
Former [2018/10]EE11.11.2015
HR11.11.2015
LT11.11.2015
LV11.11.2015
MC11.11.2015
RO11.11.2015
SI11.11.2015
SK11.11.2015
SM11.11.2015
GR12.02.2016
IS11.03.2016
LU20.08.2016
Former [2017/44]DK11.11.2015
EE11.11.2015
HR11.11.2015
LT11.11.2015
LV11.11.2015
MC11.11.2015
RO11.11.2015
SI11.11.2015
SK11.11.2015
SM11.11.2015
GR12.02.2016
IS11.03.2016
LU20.08.2016
Former [2017/23]DK11.11.2015
EE11.11.2015
HR11.11.2015
LT11.11.2015
LV11.11.2015
MC11.11.2015
RO11.11.2015
SI11.11.2015
SK11.11.2015
SM11.11.2015
GR12.02.2016
IS11.03.2016
Former [2016/49]DK11.11.2015
EE11.11.2015
HR11.11.2015
LT11.11.2015
LV11.11.2015
RO11.11.2015
SI11.11.2015
SK11.11.2015
SM11.11.2015
GR12.02.2016
IS11.03.2016
Former [2016/39]DK11.11.2015
EE11.11.2015
HR11.11.2015
LT11.11.2015
LV11.11.2015
RO11.11.2015
SK11.11.2015
SM11.11.2015
GR12.02.2016
IS11.03.2016
Former [2016/38]EE11.11.2015
HR11.11.2015
LT11.11.2015
LV11.11.2015
RO11.11.2015
SK11.11.2015
SM11.11.2015
GR12.02.2016
IS11.03.2016
Former [2016/36]EE11.11.2015
HR11.11.2015
LT11.11.2015
LV11.11.2015
RO11.11.2015
SK11.11.2015
GR12.02.2016
IS11.03.2016
Former [2016/25]HR11.11.2015
LT11.11.2015
LV11.11.2015
GR12.02.2016
IS11.03.2016
Former [2016/24]HR11.11.2015
LT11.11.2015
GR12.02.2016
IS11.03.2016
Former [2016/23]HR11.11.2015
LT11.11.2015
IS11.03.2016
Former [2016/22]LT11.11.2015
IS11.03.2016
Former [2016/20]LT11.11.2015
Cited inInternational search[A]US6465624  (FISCHER BERNHARD [AT], et al) [A] 13-15 * the whole document * * abstract * * column 3, line 45 - line 54 * * column 4, line 59 - line 62 * * column 6, line 11 - line 22 * * column 6, line 45 - line 52 * * column 11, line 14 - column 12, line 32; example 3 * * claims 1, 8 * * claim 13 *;
 [I]  - CAMERON R ET AL, "The removal of model viruses, poliovirus type 1 and canine parvovirus, during the purification of human albumin using ion-exchange chromatographic procedures.", BIOLOGICALS : JOURNAL OF THE INTERNATIONAL ASSOCIATION OF BIOLOGICAL STANDARDIZATION DEC 1997 LNKD- PUBMED:9467035, (199712), vol. 25, no. 4, doi:10.1006/biol.1997.0115, ISSN 1045-1056, pages 391 - 401, XP002610211 [I] 1-12 * the whole document * * abstract * * page 392, column r, paragraph 1 * * "Discussion"; page 399 - page 400 *

DOI:   http://dx.doi.org/10.1006/BIOL.1997.0115
 [I]  - Chapter 9, "Ion Exchange Chromatography", Chapter 9, Bollag DM, Rozycki MD, Edelstein SJ, Protein Methods (2nd edition), New York, NY, Wiley-Liss, Inc., (1996), XP002609616 [I] 1-12 * page 231 - page 239 *
 [A]  - CHANDRA SUDHISH ET AL, "Effectiveness of alternative treatments for reducing potential viral contaminants from plasma-derived products.", THROMBOSIS RESEARCH 1 MAR 2002 LNKD- PUBMED:12062540, (20020301), vol. 105, no. 5, doi:10.1016/S0049-3848(02)00044-0, ISSN 0049-3848, pages 391 - 400, XP002610212 [A] 13-15 * the whole document * * abstract * * section 3.2. "Purification steps that reduce viral contamination"; page 393 *

DOI:   http://dx.doi.org/10.1016/S0049-3848(02)00044-0
 [A]  - SOLHEIM ET AL, "Pathogen reduction of blood components", TRANSFUSION AND APHERESIS SCIENCE, ELSEVIER SCIENCE, LONDON, GB, vol. 39, no. 1, doi:DOI:10.1016/J.TRANSCI.2008.05.003, ISSN 1473-0502, (20080801), pages 75 - 82, (20080703), XP023613846 [A] 13-15 * the whole document * * abstract *

DOI:   http://dx.doi.org/10.1016/j.transci.2008.05.003
 [A]  - PROWSE ET AL, "Properties of Pathogen-Inactivated Plasma Components", TRANSFUSION MEDICINE REVIEWS, GRUNE AND STRATTON, ORLANDO, FL, US, vol. 23, no. 2, doi:DOI:10.1016/J.TMRV.2008.12.004, ISSN 0887-7963, (20090401), pages 124 - 133, (20090320), XP026017877 [A] 13-15 * the whole document * * abstract * * table 1 * * table 4 *

DOI:   http://dx.doi.org/10.1016/j.tmrv.2008.12.004
by applicantUS3941763
 WO8606096
 US7005502
 US2006160948
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 US19900559509
OppositionEP0934748
 US2002058625
 US6465624
    - JOHNSTON ADCOCK;, Biotechnology and Genetic Engineering Reviews, (20000000), vol. 17
    - CAMERON et al., "the removal of model viruses poliovirus type 1 and canine parvovirus", Biologicals, (19970000), vol. 25, pages 391 - 401, XP002610211

DOI:   http://dx.doi.org/10.1006/BIOL.1997.0115
    - 3.9 Characterization, purfication and determination of protein structure and organization, Textbook of Biochemistry with Clinical Correlations, Wiley, pages 117 - 118, XP055385074
    - CAMERON et al., "the removal of model viruses poliovirus type 1 and canine parvovirus", Biologicals, (19970000), vol. 25, pages 391 - 401
    - Exhibit 1: experimental study relating to example 3 of D2
    - Pharmacia LKB Biotechnology AB, 1991. Ion exchange chromatography principles and methods (3rd edition) Pharmacia, Uppsala, Sweden
    - Declaration 12 4.2017 relating to the experimental study of D07
    - Declaration 23.11.2017 relating to an experimental study relating to example 3 of D2
    - Declaration Piers Acland QC relating to experimental study relating to example 3 of D2
The EPO accepts no responsibility for the accuracy of data originating from other authorities; in particular, it does not guarantee that it is complete, up to date or fit for specific purposes.