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Extract from the Register of European Patents

EP About this file: EP2432794

EP2432794 - TRANS-ACTING RNA SWITCHES [Right-click to bookmark this link]
StatusNo opposition filed within time limit
Status updated on  06.07.2018
Database last updated on 05.10.2024
FormerThe patent has been granted
Status updated on  28.07.2017
FormerGrant of patent is intended
Status updated on  08.03.2017
Most recent event   Tooltip10.07.2020Lapse of the patent in a contracting state
New state(s): AL		published on 12.08.2020  [2020/33]
Applicant(s)For all designated states
The Research Foundation of State University of New York
1400 Washington Avenue
Albany, New York 12222 / US
[2012/13]
Inventor(s)01 / TENENBAUM, Scott, A.
9 Ashgrove Lane
Selkirk, NY 12158 / US
02 / DOYLE, Francis, Joseph, II.
1702 Western Avenue Apt. 2-112
Albany, NY 12203 / US
03 / GEORGE, Ajish
3 Pheasant Run Court
Timonium, MD 21093 / US
04 / ZALESKI, Christopher
140 Wall St. Apt. 7
Huntington, NY 11743 / US
 [2012/13]
Representative(s)Sharples, Andrew John, et al
EIP Fairfax House 15 Fulwood Place
London WC1V 6HU / GB
[2012/13]
Application number, filing date10778508.121.05.2010
[2017/35]
WO2010US35870
Priority number, dateUS20090180670P22.05.2009         Original published format: US 180670 P
[2012/13]
Filing languageEN
Procedural languageEN
PublicationType: A1 Application with search report
No.:WO2010135716
Date:25.11.2010
Language:EN
[2010/47]
Type: A1 Application with search report 
No.:EP2432794
Date:28.03.2012
Language:EN
The application published by WIPO in one of the EPO official languages on 25.11.2010 takes the place of the publication of the European patent application.
[2012/13]
Type: B1 Patent specification 
No.:EP2432794
Date:30.08.2017
Language:EN
[2017/35]
Search report(s)International search report - published on:US25.11.2010
(Supplementary) European search report - dispatched on:EP23.01.2014
ClassificationIPC:C07H21/02, A61K31/7105
[2012/13]
CPC:
C12N15/111 (EP,US); C12N15/113 (US); G01N33/5005 (EP,US);
G01N33/5308 (EP,US); C12N2310/113 (EP,US); C12N2310/141 (EP,US);
C12N2310/531 (US); C12N2320/50 (EP,US); C12N2330/51 (EP,US) (-)
Designated contracting statesAL,   AT,   BE,   BG,   CH,   CY,   CZ,   DE,   DK,   EE,   ES,   FI,   FR,   GB,   GR,   HR,   HU,   IE,   IS,   IT,   LI,   LT,   LU,   LV,   MC,   MK,   MT,   NL,   NO,   PL,   PT,   RO,   SE,   SI,   SK,   SM,   TR [2012/13]
Extension statesBANot yet paid
MENot yet paid
RSNot yet paid
TitleGerman:RNA-UMSCHALTER MIT TRANS-WIRKUNG[2012/13]
English:TRANS-ACTING RNA SWITCHES[2012/13]
French:PERMUTATIONS D'ARN DE TRANSACTIVATION[2012/13]
Entry into regional phase22.12.2011National basic fee paid 
22.12.2011Search fee paid 
22.12.2011Designation fee(s) paid 
22.12.2011Examination fee paid 
Examination procedure22.12.2011Examination requested  [2012/13]
20.08.2014Amendment by applicant (claims and/or description)
22.12.2014Despatch of a communication from the examining division (Time limit: M06)
01.07.2015Reply to a communication from the examining division
09.03.2016Despatch of a communication from the examining division (Time limit: M04)
18.07.2016Reply to a communication from the examining division
09.03.2017Communication of intention to grant the patent
19.07.2017Fee for grant paid
19.07.2017Fee for publishing/printing paid
19.07.2017Receipt of the translation of the claim(s)
Divisional application(s)The date of the Examining Division's first communication in respect of the earliest application for which a communication has been issued is  22.12.2014
Opposition(s)31.05.2018No opposition filed within time limit [2018/32]
Fees paidRenewal fee
25.05.2012Renewal fee patent year 03
28.05.2013Renewal fee patent year 04
27.05.2014Renewal fee patent year 05
27.05.2015Renewal fee patent year 06
27.05.2016Renewal fee patent year 07
30.05.2017Renewal fee patent year 08
Opt-out from the exclusive  Tooltip
competence of the Unified
Patent Court		 See the Register of the Unified Patent Court for opt-out data
Responsibility for the accuracy, completeness or quality of the data displayed under the link provided lies entirely with the Unified Patent Court.
Lapses during opposition  TooltipHU21.05.2010
AL30.08.2017
AT30.08.2017
CY30.08.2017
CZ30.08.2017
DK30.08.2017
EE30.08.2017
ES30.08.2017
FI30.08.2017
HR30.08.2017
IT30.08.2017
LT30.08.2017
LV30.08.2017
MC30.08.2017
MK30.08.2017
NL30.08.2017
PL30.08.2017
PT30.08.2017
RO30.08.2017
SE30.08.2017
SI30.08.2017
SK30.08.2017
SM30.08.2017
TR30.08.2017
BG30.11.2017
NO30.11.2017
GR01.12.2017
IS30.12.2017
IE21.05.2018
LU21.05.2018
MT21.05.2018
[2020/33]
Former [2020/31]HU21.05.2010
AT30.08.2017
CY30.08.2017
CZ30.08.2017
DK30.08.2017
EE30.08.2017
ES30.08.2017
FI30.08.2017
HR30.08.2017
IT30.08.2017
LT30.08.2017
LV30.08.2017
MC30.08.2017
MK30.08.2017
NL30.08.2017
PL30.08.2017
PT30.08.2017
RO30.08.2017
SE30.08.2017
SI30.08.2017
SK30.08.2017
SM30.08.2017
TR30.08.2017
BG30.11.2017
NO30.11.2017
GR01.12.2017
IS30.12.2017
IE21.05.2018
LU21.05.2018
MT21.05.2018
Former [2020/27]HU21.05.2010
AT30.08.2017
CZ30.08.2017
DK30.08.2017
EE30.08.2017
ES30.08.2017
FI30.08.2017
HR30.08.2017
IT30.08.2017
LT30.08.2017
LV30.08.2017
MC30.08.2017
NL30.08.2017
PL30.08.2017
PT30.08.2017
RO30.08.2017
SE30.08.2017
SI30.08.2017
SK30.08.2017
SM30.08.2017
TR30.08.2017
BG30.11.2017
NO30.11.2017
GR01.12.2017
IS30.12.2017
IE21.05.2018
LU21.05.2018
MT21.05.2018
Former [2020/16]AT30.08.2017
CZ30.08.2017
DK30.08.2017
EE30.08.2017
ES30.08.2017
FI30.08.2017
HR30.08.2017
IT30.08.2017
LT30.08.2017
LV30.08.2017
MC30.08.2017
NL30.08.2017
PL30.08.2017
RO30.08.2017
SE30.08.2017
SI30.08.2017
SK30.08.2017
SM30.08.2017
TR30.08.2017
BG30.11.2017
NO30.11.2017
GR01.12.2017
IS30.12.2017
IE21.05.2018
LU21.05.2018
MT21.05.2018
Former [2020/08]AT30.08.2017
CZ30.08.2017
DK30.08.2017
EE30.08.2017
ES30.08.2017
FI30.08.2017
HR30.08.2017
IT30.08.2017
LT30.08.2017
LV30.08.2017
MC30.08.2017
NL30.08.2017
PL30.08.2017
RO30.08.2017
SE30.08.2017
SI30.08.2017
SK30.08.2017
SM30.08.2017
BG30.11.2017
NO30.11.2017
GR01.12.2017
IS30.12.2017
IE21.05.2018
LU21.05.2018
MT21.05.2018
Former [2019/19]AT30.08.2017
CZ30.08.2017
DK30.08.2017
EE30.08.2017
ES30.08.2017
FI30.08.2017
HR30.08.2017
IT30.08.2017
LT30.08.2017
LV30.08.2017
MC30.08.2017
NL30.08.2017
PL30.08.2017
RO30.08.2017
SE30.08.2017
SI30.08.2017
SK30.08.2017
SM30.08.2017
BG30.11.2017
NO30.11.2017
GR01.12.2017
IS30.12.2017
IE21.05.2018
LU21.05.2018
Former [2019/17]AT30.08.2017
CZ30.08.2017
DK30.08.2017
EE30.08.2017
ES30.08.2017
FI30.08.2017
HR30.08.2017
IT30.08.2017
LT30.08.2017
LV30.08.2017
MC30.08.2017
NL30.08.2017
PL30.08.2017
RO30.08.2017
SE30.08.2017
SI30.08.2017
SK30.08.2017
SM30.08.2017
BG30.11.2017
NO30.11.2017
GR01.12.2017
IS30.12.2017
LU21.05.2018
Former [2019/06]AT30.08.2017
CZ30.08.2017
DK30.08.2017
EE30.08.2017
ES30.08.2017
FI30.08.2017
HR30.08.2017
IT30.08.2017
LT30.08.2017
LV30.08.2017
MC30.08.2017
NL30.08.2017
PL30.08.2017
RO30.08.2017
SE30.08.2017
SI30.08.2017
SK30.08.2017
SM30.08.2017
BG30.11.2017
NO30.11.2017
GR01.12.2017
IS30.12.2017
Former [2018/39]AT30.08.2017
CZ30.08.2017
DK30.08.2017
EE30.08.2017
ES30.08.2017
FI30.08.2017
HR30.08.2017
IT30.08.2017
LT30.08.2017
LV30.08.2017
NL30.08.2017
PL30.08.2017
RO30.08.2017
SE30.08.2017
SI30.08.2017
SK30.08.2017
SM30.08.2017
BG30.11.2017
NO30.11.2017
GR01.12.2017
IS30.12.2017
Former [2018/24]AT30.08.2017
CZ30.08.2017
DK30.08.2017
EE30.08.2017
ES30.08.2017
FI30.08.2017
HR30.08.2017
IT30.08.2017
LT30.08.2017
LV30.08.2017
NL30.08.2017
PL30.08.2017
RO30.08.2017
SE30.08.2017
SK30.08.2017
SM30.08.2017
BG30.11.2017
NO30.11.2017
GR01.12.2017
IS30.12.2017
Former [2018/23]AT30.08.2017
CZ30.08.2017
DK30.08.2017
EE30.08.2017
ES30.08.2017
FI30.08.2017
HR30.08.2017
LT30.08.2017
LV30.08.2017
NL30.08.2017
PL30.08.2017
RO30.08.2017
SE30.08.2017
SK30.08.2017
BG30.11.2017
NO30.11.2017
GR01.12.2017
IS30.12.2017
Former [2018/21]AT30.08.2017
CZ30.08.2017
DK30.08.2017
ES30.08.2017
FI30.08.2017
HR30.08.2017
LT30.08.2017
LV30.08.2017
NL30.08.2017
SE30.08.2017
BG30.11.2017
NO30.11.2017
GR01.12.2017
IS30.12.2017
Former [2018/15]AT30.08.2017
ES30.08.2017
FI30.08.2017
HR30.08.2017
LT30.08.2017
LV30.08.2017
NL30.08.2017
SE30.08.2017
BG30.11.2017
NO30.11.2017
GR01.12.2017
IS30.12.2017
Former [2018/12]AT30.08.2017
ES30.08.2017
FI30.08.2017
HR30.08.2017
LT30.08.2017
LV30.08.2017
SE30.08.2017
BG30.11.2017
NO30.11.2017
GR01.12.2017
IS30.12.2017
Former [2018/11]AT30.08.2017
ES30.08.2017
FI30.08.2017
HR30.08.2017
LT30.08.2017
SE30.08.2017
BG30.11.2017
NO30.11.2017
GR01.12.2017
IS30.12.2017
Former [2018/10]AT30.08.2017
FI30.08.2017
HR30.08.2017
LT30.08.2017
SE30.08.2017
NO30.11.2017
Former [2018/09]FI30.08.2017
LT30.08.2017
SE30.08.2017
NO30.11.2017
Former [2018/08]FI30.08.2017
LT30.08.2017
NO30.11.2017
Former [2018/07]LT30.08.2017
NO30.11.2017
Documents cited:Search[X]WO2004046321  (UNIV BOSTON [US], et al) [X] 1,10 * the whole document *;
 [X]WO2007041213  (ST JUDE CHILDRENS RES HOSPITAL [US], et al) [X] 1,10 * the whole document *;
 [X]  - VICKERS T A ET AL, "Enhancement of ribosomal frameshifting by oligonucleotides targeted to the HIV gag-pol region", NUCLEIC ACIDS RESEARCH, INFORMATION RETRIEVAL LTD, (19920101), vol. 20, no. 15, ISSN 0305-1048, pages 3945 - 3953, XP002997128 [X] 1,10 * the whole document *
 [X]  - ISAACS F J ET AL, "Engineered riboregulators enable post-transcriptional control of gene expression", NATURE BIOTECHNOLOGY, NATURE PUBLISHING GROUP, NEW YORK, NY, US, (20040701), vol. 22, no. 7, ISSN 1087-0156, pages 841 - 847, XP003002036 [X] 1,10 * the whole document *
 [X]  - SHINSUKE SANDO ET AL, "Doubly Catalytic Sensing of HIV-1-Related CCR5 Sequence in Prokaryotic Cell-Free Translation System using Riboregulator-Controlled Luciferase Activity", JOURNAL OF THE AMERICAN CHEMICAL SOCIETY, (20050401), vol. 127, no. 15, doi:10.1021/ja0507057, ISSN 0002-7863, pages 5300 - 5301, XP055079912 [X] 1,10 * the whole document *

DOI:   http://dx.doi.org/10.1021/ja0507057
 [X]  - KHATTAB A F ET AL, "IMPROVED TARGETING OF THE FLANKS OF A DNA STEM USING ALPHA-OLIGODEOXYNUCLEOTIDES-THE ENHANCED EFFECT OF AN INTERCALATOR", NUCLEOSIDES & NUCLEOTIDES, MARCEL DEKKER INC, US, (19981201), vol. 17, no. 12, ISSN 0732-8311, pages 2351 - 2365, XP001085321 [X] 1,10 * the whole document *
 [X]  - J. L. CHILDS, "Oligonucleotide directed misfolding of RNA inhibits Candida albicans group I intron splicing", PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES, (20020820), vol. 99, no. 17, doi:10.1073/pnas.172391199, ISSN 0027-8424, pages 11091 - 11096, XP055079409 [X] 1,10 * the whole document *

DOI:   http://dx.doi.org/10.1073/pnas.172391199
 [X]  - Silverman S.K, Nucleic Acid Switches and Sensors, NUCLEIC ACID SWITCHES AND SENSORS SPRINGER, 233 SPRING STREET, NEW YORK, NY 10013, UNITED STATES SERIES : MOLECULAR BIOLOGY INTELLIGENCE UNIT, (2006), ISSN null, XP002713380 [X] 1,10 * the whole document *
International search[Y]US5554528  (HARRISON GAIL M [US], et al);
 [Y]US5593863  (EBERWINE JAMES H [US], et al);
 [X]US2005282190  (SHI HUA [US], et al);
 [Y]  - GORGONI ET AL., "The stem-loop binding protein stimulates histone translation at an early step in the initiation pathway", RNA, (2005), vol. 11, pages 1030 - 1042, XP008148597

DOI:   http://dx.doi.org/10.1261/rna.7281305
by applicant   - COLLER ET AL., GENES AND DEVELOPMENT, (1998), vol. 12, pages 3226 - 3235
    - LECUYE ET AL., BIOCHEM., (1995), vol. 34, no. 33, pages 10600 - 10606
The EPO accepts no responsibility for the accuracy of data originating from other authorities; in particular, it does not guarantee that it is complete, up to date or fit for specific purposes.