blank Quick help
blank Maintenance news

Scheduled maintenance

Regular maintenance outages:
between 05.00 and 05.15 hrs CET (Monday to Sunday).

Other outages
Availability

2022.02.11

More...
blank News flashes

News Flashes

New version of the European Patent Register – SPC proceedings information in the Unitary Patent Register.

2024-07-24

More...
blank Related links

Extract from the Register of European Patents

EP About this file: EP2440251

EP2440251 - ADMINISTRATION OF INTERFERON FOR PROPHYLAXIS AGAINST OR TREATMENT OF PATHOGENIC INFECTION [Right-click to bookmark this link]
StatusThe application is deemed to be withdrawn
Status updated on  18.08.2017
Database last updated on 16.11.2024
FormerGrant of patent is intended
Status updated on  08.11.2016
Most recent event   Tooltip18.08.2017Application deemed to be withdrawnpublished on 20.09.2017  [2017/38]
Applicant(s)For all designated states
Defyrus, Inc .
Suite 2602 2 Bloor Street
Toronto, Ontario M4W 3E2 / CA
[2012/16]
Inventor(s)01 / TURNER, Jeffrey D.
Suite 2602
2 Bloor Street
Toronto Ontario M4W 3E2 / CA
02 / ENNIS, Jane E .
Suite 2602
2 Bloor Street
Toronto Ontario M4W 3E2 / CA
 [2012/16]
Representative(s)HGF
HGF Limited
Mill House
North Street
York YO1 6JD / GB
[N/P]
Former [2012/16]Harrison Goddard Foote
Saviour House
9 St Saviourgate
York
YO1 8NQ / GB
Application number, filing date10785615.508.06.2010
WO2010CA00844
Priority number, dateUS20090185261P09.06.2009         Original published format: US 185261 P
[2012/16]
Filing languageEN
Procedural languageEN
PublicationType: A1 Application with search report
No.:WO2010142017
Date:16.12.2010
Language:EN
[2010/50]
Type: A1 Application with search report 
No.:EP2440251
Date:18.04.2012
Language:EN
The application published by WIPO in one of the EPO official languages on 16.12.2010 takes the place of the publication of the European patent application.
[2012/16]
Search report(s)International search report - published on:CA16.12.2010
(Supplementary) European search report - dispatched on:EP19.12.2012
ClassificationIPC:A61K38/21, A61K48/00, A61K9/00
[2016/44]
CPC:
A61K38/212 (EP,US); A61K39/12 (US); A61K48/005 (EP,US);
A61K9/0073 (US); A61M11/02 (US); A61M15/00 (US);
A61M16/14 (US); A61P31/00 (EP); A61P31/04 (EP);
A61P31/10 (EP); A61P31/12 (EP); A61P31/14 (EP);
A61P31/16 (EP); A61P31/18 (EP); A61P31/20 (EP);
A61P31/22 (EP); A61P33/00 (EP); A61P33/02 (EP);
A61P33/06 (EP); A61P35/00 (EP); A61P37/00 (EP);
A61P37/02 (EP); A61P37/04 (EP); C12N15/86 (US);
A61K9/0043 (EP,US); A61K9/007 (EP,US); C12N2799/022 (EP,US);
Y02A50/30 (EP,US) (-)
Former IPC [2012/16]A61K48/00, A61P31/00, A61P37/04, A61K38/21
Designated contracting statesAL,   AT,   BE,   BG,   CH,   CY,   CZ,   DE,   DK,   EE,   ES,   FI,   FR,   GB,   GR,   HR,   HU,   IE,   IS,   IT,   LI,   LT,   LU,   LV,   MC,   MK,   MT,   NL,   NO,   PL,   PT,   RO,   SE,   SI,   SK,   SM,   TR [2012/16]
TitleGerman:VERABREICHUNG VON INTERFERON ZUR PROPHYLAXE GEGEN ODER ZUR BEHANDLUNG VON KRANKHEITSERREGENDEN INFEKTIONEN[2012/16]
English:ADMINISTRATION OF INTERFERON FOR PROPHYLAXIS AGAINST OR TREATMENT OF PATHOGENIC INFECTION[2012/16]
French:ADMINISTRATION D'INTERFÉRON POUR UNE PROPHYLAXIE CONTRE UNE INFECTION PATHOGÈNE OU UN TRAITEMENT D'UNE INFECTION PATHOGÈNE[2012/16]
Entry into regional phase09.01.2012National basic fee paid 
09.01.2012Search fee paid 
09.01.2012Designation fee(s) paid 
09.01.2012Examination fee paid 
Examination procedure09.01.2012Examination requested  [2012/16]
17.07.2013Amendment by applicant (claims and/or description)
06.08.2015Despatch of a communication from the examining division (Time limit: M06)
19.05.2016Reply to a communication from the examining division
17.08.2016Despatch of a communication from the examining division (Time limit: M01)
19.09.2016Reply to a communication from the examining division
09.11.2016Communication of intention to grant the patent
21.03.2017Application deemed to be withdrawn, date of legal effect  [2017/38]
26.04.2017Despatch of communication that the application is deemed to be withdrawn, reason: fee for grant / fee for printing not paid in time  [2017/38]
Divisional application(s)The date of the Examining Division's first communication in respect of the earliest application for which a communication has been issued is  06.08.2015
Request for further processing for:The application is deemed to be withdrawn due to failure to reply to the examination report
19.05.2016Request for further processing filed
19.05.2016Full payment received (date of receipt of payment)
Request granted
27.05.2016Decision despatched
Fees paidRenewal fee
26.06.2012Renewal fee patent year 03
27.06.2013Renewal fee patent year 04
30.06.2014Renewal fee patent year 05
29.06.2015Renewal fee patent year 06
27.06.2016Renewal fee patent year 07
Penalty fee
Additional fee for renewal fee
30.06.201708   M06   Not yet paid
Opt-out from the exclusive  Tooltip
competence of the Unified
Patent Court
See the Register of the Unified Patent Court for opt-out data
Responsibility for the accuracy, completeness or quality of the data displayed under the link provided lies entirely with the Unified Patent Court.
Documents cited:Search[XI]US5789245  (DUBENSKY JR THOMAS W [US], et al) [X] 1-7,10 * column 7, line 4 - line 13 * * column 7, line 60 - column 8, line 55 * * column 12, line 43 - column 19, line 58 * * column 21, line 16 - line 20 * * column 37, line 24 - line 32 * * column 43, line 56 - line 64 * * column 44, line 10 - line 44 * * column 151, line 25 - column 152, line 63 * * column 48, line 29 - column 50, line 49 * * column 153, line 47 - column 154, line 2 * * column 154, line 35 - line 50 * * column 130, line 48 - column 140, line 31 *[I] 11-15
International search[Y]EP0422697  (AMGEN INC [US]);
 [Y]WO9742323  (AMGEN INC [US], et al);
 [Y]WO9817801  (CANJI INC [US], et al);
 [X]WO0009086  (VALENTIS INC [US], et al);
 [Y]WO0009675  (AVENTIS PHARM PROD INC [US], et al);
 [Y]EP1078639  (SUMITOMO PHARMA [JP], et al);
ExaminationUS2006147466
    - M. B. Appaiahgari ET AL, "Seroprevalence of Neutralizing Antibodies to Adenovirus Type 5 among Children in India: Implications for Recombinant Adenovirus-Based Vaccines", CLINICAL AND VACCINE IMMUNOLOGY, US, (20070801), vol. 14, no. 8, doi:10.1128/CVI.00173-07, ISSN 1556-6811, pages 1053 - 1055, XP055309802

DOI:   http://dx.doi.org/10.1128/CVI.00173-07
    - Mauro P Moraes ET AL, "pAd5-Blue: Direct Liga - tion System for Engineer - ing Recombinant Adeno - virus Constructs", BioTechniques, (20010901), vol. 31, pages 1050 - 1056, XP055309809
    - BLATT L M ET AL, "THE BIOLOGIC ACTIVITY AND MOLECULAR CHARACTERIZATION OF A NOVEL SYNTHETIC INTERFERON-ALPHA SPECIES, CONSENSUS INTERFERON", JOURNAL OF INTERFERON AND CYTOKINE RESEARCH, MARY ANN LIEBERT, NEW YORK, NY, US, (19960101), vol. 16, no. 7, ISSN 1079-9907, pages 489 - 499, XP009023878
    - THE STEP STUDY PROTOCOL TEAM ET AL, "Efficacy assessment of a cell-mediated immunity HIV-1 vaccine (the Step Study): a double-blind, randomised, placebo-controlled, test-of-concept trial", THE LANCET, THE LANCET PUBLISHING GROUP, GB, vol. 372, no. 9653, doi:10.1016/S0140-6736(08)61591-3, ISSN 0140-6736, (20081129), pages 1881 - 1893, (20081127), XP025710769

DOI:   http://dx.doi.org/10.1016/S0140-6736(08)61591-3
    - CHINSANGARAM J ET AL, "Novel viral disease control strategy: adenovirus expressing alpha interferon rapidly protects swine from foot-and-mouth disease", JOURNAL OF VIROLOGY, THE AMERICAN SOCIETY FOR MICROBIOLOGY, US, (20030101), vol. 77, no. 2, doi:10.1128/JVI.77.2.1621-1625.2003, ISSN 0022-538X, pages 1621 - 1625, XP008110911

DOI:   http://dx.doi.org/10.1128/JVI.77.2.1621-1625.2003
    - Anonymous, "General Approach to the Poisoned Patient", Medical toxicology, (20040101), page 512, XP055309834
    - G Demers, "Interferon-[alpha]2b Secretion by Adenovirus-Mediated Gene Delivery in Rat, Rabbit, and Chimpanzee Results in Similar Pharmacokinetic Profiles", Toxicology and Applied Pharmacology, (20020401), vol. 180, no. 1, doi:10.1006/taap.2002.9372, ISSN 0041-008X, pages 36 - 42, XP055069557

DOI:   http://dx.doi.org/10.1006/taap.2002.9372
    - Brian B. Gowen ET AL, "Use of Recombinant Adenovirus Vectored Consensus IFN-[alpha] to Avert Severe Arenavirus Infection", PL o S One, US, (20110101), vol. 6, no. 10, doi:10.1371/journal.pone.0026072, ISSN 1932-6203, pages e26072 - e26072, XP055309839

DOI:   http://dx.doi.org/10.1371/journal.pone.0026072
    - GUTIERRO I ET AL, "Influence of dose and immunization route on the serum Ig G antibody response to BSA loaded PLGA microspheres", VACCINE, ELSEVIER LTD, GB, (20020522), vol. 20, no. 17-18, doi:10.1016/S0264-410X(02)00146-9, ISSN 0264-410X, pages 2181 - 2190, XP004353923

DOI:   http://dx.doi.org/10.1016/S0264-410X(02)00146-9
    - HUANG J ET AL, "A novel dry powder influenza vaccine and intranasal delivery technology: induction of systemic and mucosal immune responses in rats", VACCINE, ELSEVIER LTD, GB, (20041221), vol. 23, no. 6, doi:10.1016/J.VACCINE.2004.06.049, ISSN 0264-410X, pages 794 - 801, XP004637086

DOI:   http://dx.doi.org/10.1016/j.vaccine.2004.06.049
    - A Isaacs ET AL, "Virus Interference. I. The Interferon", Proc R Soc Lond, (19570101), vol. 147, pages 258 - 267, XP055309879

DOI:   http://dx.doi.org/10.1098/rspb.1957.0048
    - Douglas J Jolly ET AL, "Adenoviral Vectors: History and Perspective", Concepts in Medicine, Wiley-Liss, (20080101), pages 39 - 54, ISBN 978-0-471-70320-4, XP055309935

DOI:   http://dx.doi.org/10.1002/9780470184585.ch4
    - J. G. Julander ET AL, "Treatment of Yellow Fever Virus with an Adenovirus-Vectored Interferon, DEF201, in a Hamster Model", ANTIMICROBIAL AGENTS AND CHEMOTHERAPY, US, (20110207), vol. 55, no. 5, doi:10.1128/AAC.01635-10, ISSN 0066-4804, pages 2067 - 2073, XP055309941

DOI:   http://dx.doi.org/10.1128/AAC.01635-10
    - V. Keedy ET AL, "Phase I Study of Adenovirus p53 Administered by Bronchoalveolar Lavage in Patients With Bronchioloalveolar Cell Lung Carcinoma: ECOG 6597", JOURNAL OF CLINICAL ONCOLOGY, US, (20080828), vol. 26, no. 25, doi:10.1200/JCO.2007.15.6927, ISSN 0732-183X, pages 4166 - 4171, XP055309943

DOI:   http://dx.doi.org/10.1200/JCO.2007.15.6927
    - Micheal R Knowles ET AL, "A CONTROLLED STUDY OF ADENOVIRAL-VECTOR-MEDIATED GENE TRANSFER IN THE NASAL EPITHELIUM OF PATIENTS WITH CYSTIC FIBROSIS", New England Journal of Medicine, (19950928), vol. 333, pages 823 - 831, XP055309950
    - KUMAKI Y ET AL, "Single-dose intranasal administration with mDEF201 (adenovirus vectored mouse interferon-alpha) confers protection from mortality in a lethal SARS-CoV BALB/c mouse model", ANTIVIRAL RESEARCH, ELSEVIER BV, NL, vol. 89, no. 1, ISSN 0166-3542, (20110101), pages 75 - 82, (20110101), XP027586729
    - MORAES M P ET AL, "Immediate protection of swine from foot-and-mouth disease: a combination of adenoviruses expressing interferon alpha and a foot-and-mouth disease virus subunit vaccine", VACCINE, ELSEVIER LTD, GB, (20031212), vol. 22, no. 2, doi:10.1016/S0264-410X(03)00560-7, ISSN 0264-410X, pages 268 - 279, XP004472593

DOI:   http://dx.doi.org/10.1016/S0264-410X(03)00560-7
    - Mary Ann Liebert ET AL, "Assessment of adenoviral vector safety and toxicity: report of the National Institutes of Health Recombinant DNA Advisory Committee", Human gene therapy, United States, doi:10.1089/10430340152712629, (20020101), pages 3 - 13, URL: http://osp.od.nih.gov/sites/default/files/adsat_rpt.pdf, XP055309953

DOI:   http://dx.doi.org/10.1089/10430340152712629
    - Frances h. Priddy ET AL, "Safety and Immunogenicity of a Replication-Incompetent Adenovirus Type 5 HIV-1 Clade B gag/pol/nef Vaccine in Healthy Adults", CLINICAL INFECTIOUS DISEASES, US, (20080601), vol. 46, no. 11, doi:10.1086/587993, ISSN 1058-4838, pages 1769 - 1781, XP055309956

DOI:   http://dx.doi.org/10.1086/587993
    - T Reid ET AL, "Intra-arterial administration of a replication-selective adenovirus (dl1520) in patients with colorectal carcinoma metastatic to the liver: a phase I trial", Gene Therapy, GB, (20011101), vol. 8, no. 21, doi:10.1038/sj.gt.3301512, ISSN 0969-7128, pages 1618 - 1626, XP055309958

DOI:   http://dx.doi.org/10.1038/sj.gt.3301512
    - Donald F. Smee ET AL, "Therapy and Long-Term Prophylaxis of Vaccinia Virus Respiratory Infections in Mice with an Adenovirus-Vectored Interferon Alpha (mDEF201)", PLoS ONE, (20111013), vol. 6, no. 10, doi:10.1371/journal.pone.0026330, page e26330, XP055309962

DOI:   http://dx.doi.org/10.1371/journal.pone.0026330
    - SULLIVAN N J ET AL, "Development of a preventive vaccine for Ebola virus infection in primates", NATURE, NATURE PUBLISHING GROUP, UNITED KINGDOM, (20001130), vol. 408, no. 6812, doi:10.1038/35046108, ISSN 0028-0836, pages 605 - 609, XP002242909

DOI:   http://dx.doi.org/10.1038/35046108
    - SUMIDA SHAWN M ET AL, "Neutralizing antibodies to adenovirus serotype 5 vaccine vectors are directed primarily against the adenovirus hexon protein", THE JOURNAL OF IMMUNOLOGY, THE AMERICAN ASSOCIATION OF IMMUNOLOGISTS, US, (20050601), vol. 174, no. 11, ISSN 0022-1767, pages 7179 - 7185, XP002385299
    - THOMAS C E ET AL, "PROGRESS AND PROBLEMS WITH THE USE OF VIRAL VECTORS FOR GENE THERAPY", NATURE REVIEWS GENETICS, MACMILLAN MAGAZINES, GB, (20030501), vol. 4, no. 5, doi:10.1038/NRG1066, pages 346 - 358, XP008061799

DOI:   http://dx.doi.org/10.1038/nrg1066
    - Jonathan B. Zuckerman ET AL, "A Phase I Study of Adenovirus-Mediated Transfer of the Human Cystic Fibrosis Transmembrane Conductance Regulator Gene to a Lung Segment of Individuals with Cystic Fibrosis", Human Gene Therapy, US, (19991210), vol. 10, no. 18, doi:10.1089/10430349950016384, ISSN 1043-0342, pages 2973 - 2985, XP055309970

DOI:   http://dx.doi.org/10.1089/10430349950016384
    - Jeffrey D Turner, "Declaration of Jeffrey D. Turner PH.D. UNDER 37 C.F.R. & 1.132", (20120709), pages 1 - 8, XP055309973
    - ALBERTI A, "INTERFERON ALFACON-1: A NOVEL INTERFERON FOR THE TREATMENT OF CHRONIC HEPATITIS C", BIODRUGS,, (19990101), vol. 12, no. 5, doi:10.2165/00063030-199912050-00003, ISSN 1173-8804, pages 343 - 357, XP008072415

DOI:   http://dx.doi.org/10.2165/00063030-199912050-00003
by applicantUS4450103
 US4588585
 US4695623
 US4737462
 US4897471
 US4959314
 WO9420069
 US5372808
 US5437267
 US5522385
 US5522378
 WO9632149
 US5654007
 WO9742323
 WO9741833
 US5738845
 WO9817801
 US5775320
 WO9829096
 US5785049
 US5789245
 US5826570
 US5846526
 US5855564
 US5915378
 US5922354
 US5934272
 US5957124
 US5960792
 US5976574
 US5985248
 US5993783
 US5994314
 US5997848
 US6001336
 US6004583
 US6060450
 US6068199
 US6093550
 US6204022
 US6303582
 US6361769
 US6398774
 US6413539
 US6565853
 US6605302
 US6715485
 US2004112378
 US2004112379
 US2004149289
 US2004247565
 US2005028812
 US2005072430
 US6894033
 US6936257
 US2005235992
 US6962978
 US2006096589
 US2006169278
 US7097827
 US7105154
 US7166575
 US2007039614
 WO2007044083
 US7235391
 US7238344
 US2007186927
 US2007243163
 US2007274950
 US7347201
 US7371373
 US7387788
 US2008161771
 US2008163874
 US2008223363
 US7442527
 US7442380
 US7482024
 US7481212
 US7481218
 US7538122
 US7669597
The EPO accepts no responsibility for the accuracy of data originating from other authorities; in particular, it does not guarantee that it is complete, up to date or fit for specific purposes.