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Extract from the Register of European Patents

EP About this file: EP2513301

EP2513301 - PICHIA PASTORIS DEFICIENT IN ENDOGENOUS SECRETED PROTEASE [Right-click to bookmark this link]
StatusThe application is deemed to be withdrawn
Status updated on  15.05.2015
Database last updated on 05.10.2024
Most recent event   Tooltip15.05.2015Application deemed to be withdrawnpublished on 17.06.2015  [2015/25]
Applicant(s)For all designated states
Centre Hospitalier Universitaire Vaudois (CHUV)
Rue du Bugnon 21
1011 Lausanne / CH
[2012/43]
Inventor(s)01 / MONOD, Michel
Service de Dermatologie
BT422
Centre Hospitalier Universitaire Vaudois (CHUV)
Rue du Bugnon 21
CH-1011 Lausanne / CH
 [2012/43]
Representative(s)KATZAROV S.A.
Geneva Business Center
12 Avenue des Morgines
1213 Petit-Lancy / CH
[N/P]
Former [2012/43]KATZAROV S.A.
European Patent Attorneys 19, rue des Epinettes
1227 Genève / CH
Application number, filing date10814699.413.12.2010
WO2010IB55777
Priority number, dateWO2009IB5572914.12.2009         Original published format: PCT/IB2009/055729
[2012/43]
Filing languageEN
Procedural languageEN
PublicationType: A1 Application with search report
No.:WO2011073883
Date:23.06.2011
Language:EN
[2011/25]
Type: A1 Application with search report 
No.:EP2513301
Date:24.10.2012
Language:EN
The application published by WIPO in one of the EPO official languages on 23.06.2011 takes the place of the publication of the European patent application.
[2012/43]
Search report(s)International search report - published on:EP23.06.2011
ClassificationIPC:C12N9/60, C12N15/10, C12N15/81
[2012/43]
CPC:
C12N15/815 (EP,US); C12N9/60 (EP,US); C12P21/02 (EP,US)
Designated contracting statesAL,   AT,   BE,   BG,   CH,   CY,   CZ,   DE,   DK,   EE,   ES,   FI,   FR,   GB,   GR,   HR,   HU,   IE,   IS,   IT,   LI,   LT,   LU,   LV,   MC,   MK,   MT,   NL,   NO,   PL,   PT,   RO,   RS,   SE,   SI,   SK,   SM,   TR [2012/43]
TitleGerman:PICHIA PASTORIS OHNE ENDOGENE SEKRETIERTE PROTEASE[2012/43]
English:PICHIA PASTORIS DEFICIENT IN ENDOGENOUS SECRETED PROTEASE[2012/43]
French:PICHIA PASTORIS DÉFICIENTE EN PROTÉASE ENDOGÈNE SÉCRÉTÉE[2012/43]
Biological materialThis application mentions deposited biological material, check the file for details
Entry into regional phase14.06.2012National basic fee paid 
14.06.2012Designation fee(s) paid 
14.06.2012Examination fee paid 
Examination procedure14.06.2012Examination requested  [2012/43]
23.01.2013Amendment by applicant (claims and/or description)
26.08.2014Despatch of a communication from the examining division (Time limit: M04)
06.01.2015Application deemed to be withdrawn, date of legal effect  [2015/25]
04.02.2015Despatch of communication that the application is deemed to be withdrawn, reason: reply to the communication from the examining division not received in time  [2015/25]
Divisional application(s)The date of the Examining Division's first communication in respect of the earliest application for which a communication has been issued is  26.08.2014
Fees paidRenewal fee
29.11.2012Renewal fee patent year 03
16.12.2013Renewal fee patent year 04
Penalty fee
Additional fee for renewal fee
31.12.201405   M06   Not yet paid
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Responsibility for the accuracy, completeness or quality of the data displayed under the link provided lies entirely with the Unified Patent Court.
Cited inInternational search[XDY]US5691166  (GLEESON MARTIN A [US], et al) [XD] 1-5,7,8 * the whole document * [Y] 6;
 [XP]  - SALAMIN KARINE ET AL, "Secretion of an Endogenous Subtilisin by Pichia pastoris Strains GS115 and KM71", APPLIED AND ENVIRONMENTAL MICROBIOLOGY, (201007), vol. 76, no. 13, pages 4269 - 4276, XP002631768 [XP] 1-8 * the whole document *

DOI:   http://dx.doi.org/10.1128/AEM.00412-10
 [I]  - DE SCHUTTER KRISTOF ET AL, "Genome sequence of the recombinant protein production host Pichia pastoris", NATURE BIOTECHNOLOGY, NATURE PUBLISHING GROUP, NEW YORK, NY, US, vol. 27, no. 6, doi:DOI:10.1038/NBT.1544, ISSN 1087-0156, (20090601), page 561, (20090524), XP002544776 [I] 1-8 * the whole document * * page 565, column 2, paragraph 2 *

DOI:   http://dx.doi.org/10.1038/nbt.1544
 [I]  - "SubName: Full=Vacuolar proteinase B (YscB), a serine protease of the subtilisin family;", UniProt, (20090707), Database accession no. C4QYT0, URL: EBI, XP002631769 [I] 1-8 * compound . *
 [XY]  - MACAULEY-PATRICK SUE ET AL, "Heterologous protein production using the Pichia pastoris expression system", YEAST, JOHN WILEY & SONS LTD, GB, (20050301), vol. 22, no. 4, doi:DOI:10.1002/YEA.1208, ISSN 0749-503X, pages 249 - 270, XP002474659 [X] 1-5,7,8 * the whole document * * page 255, line 18 - line 32 * [Y] 6

DOI:   http://dx.doi.org/10.1002/yea.1208
 [A]  - SINHA JAYANTA ET AL, "Causes of proteolytic degradation of secreted recombinant proteins produced in methylotrophic yeast Pichia pastoris: Case study with recombinant ovine interferon-tau", BIOTECHNOLOGY AND BIOENGINEERING, (20050105), vol. 89, no. 1, ISSN 0006-3592, pages 102 - 112, XP002631770 [A] 1-8 * the whole document *

DOI:   http://dx.doi.org/10.1002/bit.20318
by applicantUS5691166
 WO9914347
 WO9000192
 US5190931
    - JAYANTA SINHA ET AL., BIOTECHNOLOGY AND BIOENGINEERING, (2005), vol. 89, pages 102 - 112
    - JONES, METHODS ENZYMOL, (1991), vol. 194, pages 428 - 453
    - KLIONSKY ET AL., MICROBIOL. REV., (1990), vol. 54, pages 266 - 292
    - RAYMOND ET AL., INT. REV. CYTOL., (1992), vol. 139, pages 59 - 120
    - ZHENGJUN LI ET AL., PROTEIN EXPRESSION AND PURIFICATION, (2001), vol. 21, pages 438 - 445
    - DIETHARD MATTANOVICH ET AL., MICROBIAL CELL FACTORIES, (2009), vol. 8, page 29
    - CARILLO, H.; LIPMAN, D., SIAM J. APPLIED MATH., (1988), vol. 48, page 1073
    - MILLER ET AL., MOL. CELL. BIOL., (1985), vol. 5, pages 1714 - 1721
    - MAY, G., Applied Molecular Genetics of Filamentous, BLACKIE ACADEMIC AND PROFESSIONAL, (1992), pages 1 - 25
    - TURNER, G., Vectors for Genetic Manipulation, ELSEVIER, (1994), pages 641 - 665
The EPO accepts no responsibility for the accuracy of data originating from other authorities; in particular, it does not guarantee that it is complete, up to date or fit for specific purposes.