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Extract from the Register of European Patents

EP About this file: EP2493896

EP2493896 - PHARMACEUTICAL COMPOSITION CONTAINING CYCLOMETALATED N-HETEROCYCLIC CARBENE COMPLEXES FOR CANCER TREATMENT [Right-click to bookmark this link]
StatusNo opposition filed within time limit
Status updated on  02.03.2018
Database last updated on 12.07.2024
FormerThe patent has been granted
Status updated on  24.03.2017
FormerGrant of patent is intended
Status updated on  22.01.2017
FormerExamination is in progress
Status updated on  16.12.2016
FormerGrant of patent is intended
Status updated on  14.12.2016
Most recent event   Tooltip10.07.2020Lapse of the patent in a contracting state
New state(s): AL
published on 12.08.2020  [2020/33]
Applicant(s)For all designated states
The University of Hong Kong
Pokfulam Road
Hong Kong Special Administrative Region / CN
[2012/36]
Inventor(s)01 / CHE, Chiming
Flat 5 5th Floor
Block A Parkway Court
4 Park Road
Hong Kong Special Administrative Region / CN
02 / SUN, Waiyin, Raymond
Flat D 35th Floor
Block 5 Sky Tower Sung Wong Toi Road
Kowloon
Hong Kong Special Administrative Region / CN
03 / CHOW, Lokfung
Room 309 Leung Ma House
Ma Hang Estate
Cape Road
Stanley
Hong Kong Special Administrative Region / CN
04 / YAN, Jing
Flat E
18th Floor Block 4 Serenity Place
88 Pohong Road
Tseung Kwan O.
Hong Kong Special Administrative Region / CN
 [2012/36]
Representative(s)Patentanwälte Ruff, Wilhelm, Beier, Dauster & Partner mbB
Kronenstraße 30
70174 Stuttgart / DE
[2017/17]
Former [2012/36]Patentanwälte Ruff, Wilhelm, Beier, Dauster & Partner
Kronenstrasse 30
70174 Stuttgart / DE
Application number, filing date10825938.327.10.2010
[2017/17]
WO2010CN01705
Priority number, dateUS20090255667P28.10.2009         Original published format: US 255667 P
US20100301752P05.02.2010         Original published format: US 301752 P
[2012/36]
Filing languageEN
Procedural languageEN
PublicationType: A1 Application with search report
No.:WO2011050574
Date:05.05.2011
Language:EN
[2011/18]
Type: A1 Application with search report 
No.:EP2493896
Date:05.09.2012
Language:EN
The application published by WIPO in one of the EPO official languages on 05.05.2011 takes the place of the publication of the European patent application.
[2012/36]
Type: B1 Patent specification 
No.:EP2493896
Date:26.04.2017
Language:EN
[2017/17]
Search report(s)International search report - published on:CN05.05.2011
(Supplementary) European search report - dispatched on:EP07.08.2014
ClassificationIPC:C07F1/12, C07F17/02, C07F17/00, C08F132/00, C08F134/00, A61K31/787, A61K35/00, A61P35/04, A61P35/02
[2012/36]
CPC:
A61K31/555 (EP,US); A61P35/00 (EP); A61P35/02 (EP);
A61P35/04 (EP); C07F1/00 (EP,US); C07F15/0086 (EP,US)
Designated contracting statesAL,   AT,   BE,   BG,   CH,   CY,   CZ,   DE,   DK,   EE,   ES,   FI,   FR,   GB,   GR,   HR,   HU,   IE,   IS,   IT,   LI,   LT,   LU,   LV,   MC,   MK,   MT,   NL,   NO,   PL,   PT,   RO,   RS,   SE,   SI,   SK,   SM,   TR [2012/36]
Extension statesBANot yet paid
MENot yet paid
TitleGerman:PHARMAZEUTISCHE ZUSAMMENSETZUNG MIT ZYKLOMETALLIERTEN N-HETEROZYKLISCHEN CARBENKOMPLEXEN ZUR KREBSBEHANDLUNG[2012/36]
English:PHARMACEUTICAL COMPOSITION CONTAINING CYCLOMETALATED N-HETEROCYCLIC CARBENE COMPLEXES FOR CANCER TREATMENT[2012/36]
French:COMPOSITION PHARMACEUTIQUE CONTENANT DES COMPLEXES CYCLOMÉTALLÉS DE CARBÈNES N-HÉTÉROCYCLIQUES POUR LE TRAITEMENT DU CANCER[2012/36]
Entry into regional phase27.04.2012National basic fee paid 
27.04.2012Search fee paid 
27.04.2012Designation fee(s) paid 
27.04.2012Examination fee paid 
Examination procedure27.04.2012Amendment by applicant (claims and/or description)
27.04.2012Examination requested  [2012/36]
04.06.2015Despatch of a communication from the examining division (Time limit: M06)
10.12.2015Reply to a communication from the examining division
03.08.2016Communication of intention to grant the patent
12.12.2016Disapproval of the communication of intention to grant the patent by the applicant or resumption of examination proceedings by the EPO
12.12.2016Fee for grant paid
12.12.2016Fee for publishing/printing paid
23.01.2017Communication of intention to grant the patent
16.03.2017Receipt of the translation of the claim(s)
Divisional application(s)The date of the Examining Division's first communication in respect of the earliest application for which a communication has been issued is  04.06.2015
Opposition(s)29.01.2018No opposition filed within time limit [2018/14]
Fees paidRenewal fee
11.10.2012Renewal fee patent year 03
14.10.2013Renewal fee patent year 04
14.10.2014Renewal fee patent year 05
12.10.2015Renewal fee patent year 06
11.10.2016Renewal fee patent year 07
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Responsibility for the accuracy, completeness or quality of the data displayed under the link provided lies entirely with the Unified Patent Court.
Lapses during opposition  TooltipHU27.10.2010
AL26.04.2017
AT26.04.2017
CY26.04.2017
CZ26.04.2017
DK26.04.2017
EE26.04.2017
ES26.04.2017
FI26.04.2017
HR26.04.2017
IT26.04.2017
LT26.04.2017
LV26.04.2017
MC26.04.2017
MK26.04.2017
NL26.04.2017
PL26.04.2017
PT26.04.2017
RO26.04.2017
RS26.04.2017
SE26.04.2017
SI26.04.2017
SK26.04.2017
SM26.04.2017
TR26.04.2017
BG26.07.2017
NO26.07.2017
GR27.07.2017
IS26.08.2017
IE27.10.2017
LU27.10.2017
MT27.10.2017
BE31.10.2017
[2020/33]
Former [2020/27]HU27.10.2010
AT26.04.2017
CY26.04.2017
CZ26.04.2017
DK26.04.2017
EE26.04.2017
ES26.04.2017
FI26.04.2017
HR26.04.2017
IT26.04.2017
LT26.04.2017
LV26.04.2017
MC26.04.2017
MK26.04.2017
NL26.04.2017
PL26.04.2017
PT26.04.2017
RO26.04.2017
RS26.04.2017
SE26.04.2017
SI26.04.2017
SK26.04.2017
SM26.04.2017
TR26.04.2017
BG26.07.2017
NO26.07.2017
GR27.07.2017
IS26.08.2017
IE27.10.2017
LU27.10.2017
MT27.10.2017
BE31.10.2017
Former [2020/15]HU27.10.2010
AT26.04.2017
CY26.04.2017
CZ26.04.2017
DK26.04.2017
EE26.04.2017
ES26.04.2017
FI26.04.2017
HR26.04.2017
IT26.04.2017
LT26.04.2017
LV26.04.2017
MC26.04.2017
MK26.04.2017
NL26.04.2017
PL26.04.2017
RO26.04.2017
RS26.04.2017
SE26.04.2017
SI26.04.2017
SK26.04.2017
SM26.04.2017
TR26.04.2017
BG26.07.2017
NO26.07.2017
GR27.07.2017
IS26.08.2017
IE27.10.2017
LU27.10.2017
MT27.10.2017
BE31.10.2017
Former [2019/52]HU27.10.2010
AT26.04.2017
CY26.04.2017
CZ26.04.2017
DK26.04.2017
EE26.04.2017
ES26.04.2017
FI26.04.2017
HR26.04.2017
IT26.04.2017
LT26.04.2017
LV26.04.2017
MC26.04.2017
MK26.04.2017
NL26.04.2017
PL26.04.2017
RO26.04.2017
RS26.04.2017
SE26.04.2017
SI26.04.2017
SK26.04.2017
SM26.04.2017
BG26.07.2017
NO26.07.2017
GR27.07.2017
IS26.08.2017
IE27.10.2017
LU27.10.2017
MT27.10.2017
BE31.10.2017
Former [2019/46]HU27.10.2010
AT26.04.2017
CY26.04.2017
CZ26.04.2017
DK26.04.2017
EE26.04.2017
ES26.04.2017
FI26.04.2017
HR26.04.2017
IT26.04.2017
LT26.04.2017
LV26.04.2017
MC26.04.2017
NL26.04.2017
PL26.04.2017
RO26.04.2017
RS26.04.2017
SE26.04.2017
SI26.04.2017
SK26.04.2017
SM26.04.2017
BG26.07.2017
NO26.07.2017
GR27.07.2017
IS26.08.2017
IE27.10.2017
LU27.10.2017
MT27.10.2017
BE31.10.2017
Former [2019/31]HU27.10.2010
AT26.04.2017
CZ26.04.2017
DK26.04.2017
EE26.04.2017
ES26.04.2017
FI26.04.2017
HR26.04.2017
IT26.04.2017
LT26.04.2017
LV26.04.2017
MC26.04.2017
NL26.04.2017
PL26.04.2017
RO26.04.2017
RS26.04.2017
SE26.04.2017
SI26.04.2017
SK26.04.2017
SM26.04.2017
BG26.07.2017
NO26.07.2017
GR27.07.2017
IS26.08.2017
IE27.10.2017
LU27.10.2017
MT27.10.2017
BE31.10.2017
Former [2018/45]AT26.04.2017
CZ26.04.2017
DK26.04.2017
EE26.04.2017
ES26.04.2017
FI26.04.2017
HR26.04.2017
IT26.04.2017
LT26.04.2017
LV26.04.2017
MC26.04.2017
NL26.04.2017
PL26.04.2017
RO26.04.2017
RS26.04.2017
SE26.04.2017
SI26.04.2017
SK26.04.2017
SM26.04.2017
BG26.07.2017
NO26.07.2017
GR27.07.2017
IS26.08.2017
IE27.10.2017
LU27.10.2017
MT27.10.2017
BE31.10.2017
Former [2018/43]AT26.04.2017
CZ26.04.2017
DK26.04.2017
EE26.04.2017
ES26.04.2017
FI26.04.2017
HR26.04.2017
IT26.04.2017
LT26.04.2017
LV26.04.2017
MC26.04.2017
NL26.04.2017
PL26.04.2017
RO26.04.2017
RS26.04.2017
SE26.04.2017
SI26.04.2017
SK26.04.2017
SM26.04.2017
BG26.07.2017
NO26.07.2017
GR27.07.2017
IS26.08.2017
LU27.10.2017
MT27.10.2017
BE31.10.2017
Former [2018/36]AT26.04.2017
CZ26.04.2017
DK26.04.2017
EE26.04.2017
ES26.04.2017
FI26.04.2017
HR26.04.2017
IT26.04.2017
LT26.04.2017
LV26.04.2017
MC26.04.2017
NL26.04.2017
PL26.04.2017
RO26.04.2017
RS26.04.2017
SE26.04.2017
SI26.04.2017
SK26.04.2017
SM26.04.2017
BG26.07.2017
NO26.07.2017
GR27.07.2017
IS26.08.2017
LU27.10.2017
BE31.10.2017
Former [2018/29]AT26.04.2017
CZ26.04.2017
DK26.04.2017
EE26.04.2017
ES26.04.2017
FI26.04.2017
HR26.04.2017
IT26.04.2017
LT26.04.2017
LV26.04.2017
MC26.04.2017
NL26.04.2017
PL26.04.2017
RO26.04.2017
RS26.04.2017
SE26.04.2017
SI26.04.2017
SK26.04.2017
SM26.04.2017
BG26.07.2017
NO26.07.2017
GR27.07.2017
IS26.08.2017
Former [2018/25]AT26.04.2017
CZ26.04.2017
DK26.04.2017
EE26.04.2017
ES26.04.2017
FI26.04.2017
HR26.04.2017
IT26.04.2017
LT26.04.2017
LV26.04.2017
NL26.04.2017
PL26.04.2017
RO26.04.2017
RS26.04.2017
SE26.04.2017
SI26.04.2017
SK26.04.2017
SM26.04.2017
BG26.07.2017
NO26.07.2017
GR27.07.2017
IS26.08.2017
Former [2018/11]AT26.04.2017
CZ26.04.2017
DK26.04.2017
EE26.04.2017
ES26.04.2017
FI26.04.2017
HR26.04.2017
IT26.04.2017
LT26.04.2017
LV26.04.2017
NL26.04.2017
PL26.04.2017
RO26.04.2017
RS26.04.2017
SE26.04.2017
SK26.04.2017
SM26.04.2017
BG26.07.2017
NO26.07.2017
GR27.07.2017
IS26.08.2017
Former [2018/10]AT26.04.2017
CZ26.04.2017
DK26.04.2017
EE26.04.2017
ES26.04.2017
FI26.04.2017
HR26.04.2017
LT26.04.2017
LV26.04.2017
NL26.04.2017
PL26.04.2017
RO26.04.2017
RS26.04.2017
SE26.04.2017
SK26.04.2017
BG26.07.2017
NO26.07.2017
GR27.07.2017
IS26.08.2017
Former [2018/09]AT26.04.2017
DK26.04.2017
EE26.04.2017
ES26.04.2017
FI26.04.2017
HR26.04.2017
LT26.04.2017
LV26.04.2017
NL26.04.2017
PL26.04.2017
RS26.04.2017
SE26.04.2017
BG26.07.2017
NO26.07.2017
GR27.07.2017
IS26.08.2017
Former [2017/50]AT26.04.2017
ES26.04.2017
FI26.04.2017
HR26.04.2017
LT26.04.2017
LV26.04.2017
NL26.04.2017
PL26.04.2017
RS26.04.2017
SE26.04.2017
BG26.07.2017
NO26.07.2017
GR27.07.2017
IS26.08.2017
Former [2017/49]AT26.04.2017
ES26.04.2017
FI26.04.2017
HR26.04.2017
LT26.04.2017
NL26.04.2017
NO26.07.2017
GR27.07.2017
IS26.08.2017
Former [2017/48]NL26.04.2017
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DOI:   http://dx.doi.org/10.1002/CHEM.200600117
 [A]  - VONIKA KA-MAN AU ET AL., "Luminescent cyclometalated N-heterocyclic carbene-containing organogold(III)c complexes: synthesis, characterization, electrochemistry and photophysical studies", J. AM. CHEM. SOC., (20090601), vol. 131, pages 9076 - 9085, XP002715661 [A] 1-15 * the whole document *

DOI:   http://dx.doi.org/10.1021/JA9027692
 [XP]  - JESSIE JING YAN ET AL., "Cyclometalated gold(III) complexes with N-heterocyclic carbene ligands as topoisomerase I poisons", CHEM. COMMUN., (20100419), vol. 46, pages 3893 - 3895, XP002715662 [XP] 1-4,11-15 * the whole document *

DOI:   http://dx.doi.org/10.1039/C001216E
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 [A]CN1926141  (UNIV AKRON [US])
by applicantUS2009278453
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