EP2493310 - BENZIMIDAZOLES AS FATTY ACID SYNTHASE INHIBITORS [Right-click to bookmark this link] | Status | The application is deemed to be withdrawn Status updated on 24.04.2015 Database last updated on 24.08.2024 | Most recent event Tooltip | 24.04.2015 | Application deemed to be withdrawn | published on 27.05.2015 [2015/22] | Applicant(s) | For all designated states GlaxoSmithKline LLC One Franklin Plaza 200 North 16th Street Philadelphia, PA 19102 / US | [N/P] |
Former [2012/36] | For all designated states GlaxoSmithKline LLC One Franklin Plaza 200 North 16th Street Philadelphia, PA 19102 / US | Inventor(s) | 01 /
HALLMAN, Jason Five Moore Drive Cary NC 27513 / US | 02 /
LAUDEMAN, Christopher Five Moore Drive Durham NC 27712 / US | 03 /
LIU, Ronggang Five Moore Drive Berwyn PA 19312 / US | 04 /
MILLER, Aaron Five Moore Drive Research Triangle Park NC 27709 / US | 05 /
MOORE, Michael, Lee 1250 South Collegeville Road Collegeville PA 19426 / US | 06 /
DOCK, Steven Five Moore Drive Research Triangle Park NC 27709 / US | 07 /
MUSSO, David Five Moore Drive Raleigh NC 27615 / US | 08 /
PARRISH, Cynthia 1250 South Collegeville Road Collegeville PA 19426 / US | [2012/36] | Representative(s) | Reed, Michael Antony GlaxoSmithKline Global Patents (CN925.1) 980 Great West Road Brentford, Middlesex TW8 9GS / GB | [N/P] |
Former [2012/36] | Reed, Michael Antony GlaxoSmithKline Corporate Intellectual Property (CN9.25.1) 980 Great West Road Brentford, Middlesex TW8 9GS / GB | Application number, filing date | 10828881.2 | 27.10.2010 | WO2010US54230 | Priority number, date | US20090256096P | 29.10.2009 Original published format: US 256096 P | US20090255230P | 27.10.2009 Original published format: US 255230 P | [2012/36] | Filing language | EN | Procedural language | EN | Publication | Type: | A1 Application with search report | No.: | WO2011056635 | Date: | 12.05.2011 | Language: | EN | [2011/19] | Type: | A1 Application with search report | No.: | EP2493310 | Date: | 05.09.2012 | Language: | EN | The application published by WIPO in one of the EPO official languages on 12.05.2011 takes the place of the publication of the European patent application. | [2012/36] | Search report(s) | International search report - published on: | US | 12.05.2011 | (Supplementary) European search report - dispatched on: | EP | 07.02.2014 | Classification | IPC: | A01N43/50, A61K31/415, C07D403/06, C07D403/14, C07D405/14, C07D413/14, C07D417/14, C07D471/04 | [2014/11] | CPC: |
C07D403/14 (EP,US);
A61P35/00 (EP);
A61P35/02 (EP);
A61P43/00 (EP);
C07D403/06 (EP,US);
C07D405/14 (EP,US);
|
Former IPC [2012/36] | A01N43/50, A61K31/415 | Designated contracting states | AL, AT, BE, BG, CH, CY, CZ, DE, DK, EE, ES, FI, FR, GB, GR, HR, HU, IE, IS, IT, LI, LT, LU, LV, MC, MK, MT, NL, NO, PL, PT, RO, RS, SE, SI, SK, SM, TR [2012/36] | Title | German: | BENZIMIDAZOLE ALS FETTSÄURE-SYNTHASE-HEMMER | [2012/36] | English: | BENZIMIDAZOLES AS FATTY ACID SYNTHASE INHIBITORS | [2012/36] | French: | BENZIMIDAZOLES UTILISÉS EN TANT QU'INHIBITEURS DE L'ACIDE GRAS SYNTHASE | [2012/36] | Entry into regional phase | 18.05.2012 | National basic fee paid | 18.05.2012 | Search fee paid | 18.05.2012 | Designation fee(s) paid | 18.05.2012 | Examination fee paid | Examination procedure | 18.05.2012 | Amendment by applicant (claims and/or description) | 18.05.2012 | Examination requested [2012/36] | 09.09.2014 | Application deemed to be withdrawn, date of legal effect [2015/22] | 21.11.2014 | Despatch of communication that the application is deemed to be withdrawn, reason: reply to the communication from the examining division not received in time [2015/22] | Fees paid | Renewal fee | 05.10.2012 | Renewal fee patent year 03 | 07.10.2013 | Renewal fee patent year 04 | Penalty fee | Additional fee for renewal fee | 31.10.2014 | 05   M06   Not yet paid |
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Responsibility for the accuracy, completeness or quality of the data displayed under the link provided lies entirely with the Unified Patent Court. | Documents cited: | Search | [A] - HORIGUCHI A ET AL, "Pharmacological Inhibitor of Fatty Acid Synthase Suppresses Growth and Invasiveness of Renal Cancer Cells", JOURNAL OF UROLOGY, LIPPINCOTT WILLIAMS & WILKINS, BALTIMORE, MD, US, vol. 180, no. 2, doi:10.1016/J.JURO.2008.03.186, ISSN 0022-5347, (20080801), pages 729 - 736, (20080613), XP022825417 [A] 1-12 * the whole document * DOI: http://dx.doi.org/10.1016/j.juro.2008.03.186 | [A] - XUAN WANG ET AL, "The galloyl moiety of green tea catechins is the critical structural feature to inhibit fatty-acid synthase", BIOCHEMICAL PHARMACOLOGY, (20031101), vol. 66, no. 10, doi:10.1016/S0006-2952(03)00585-9, ISSN 0006-2952, pages 2039 - 2047, XP055099173 [A] 1-12 * the whole document * DOI: http://dx.doi.org/10.1016/S0006-2952(03)00585-9 | [A] - THUPARI ET AL, "Fatty Acid Synthase Inhibition in Human Breast Cancer Cells Leads to Malonyl-CoA-Induced Inhibition of Fatty Acid Oxidation and Cytotoxicity", BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS, ACADEMIC PRESS INC. ORLANDO, FL, US, (20010713), vol. 285, no. 2, doi:10.1006/BBRC.2001.5146, ISSN 0006-291X, pages 217 - 223, XP005100767 [A] 1-12 * the whole document * DOI: http://dx.doi.org/10.1006/bbrc.2001.5146 | [A] - ZHANG S Y ET AL, "Low concentration of condensed tannins from catechu significantly inhibits fatty acid synthase and growth of MCF-7 cells", BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS, ACADEMIC PRESS INC. ORLANDO, FL, US, vol. 371, no. 4, doi:10.1016/J.BBRC.2008.04.062, ISSN 0006-291X, (20080711), pages 654 - 658, (20080422), XP022688438 [A] 1-12 * the whole document * DOI: http://dx.doi.org/10.1016/j.bbrc.2008.04.062 | [A] - YU F ET AL, "Inhibition of Coix seed extract on fatty acid synthase, a novel target for anticancer activity", JOURNAL OF ETHNOPHARMACOLOGY, ELSEVIER IRELAND LTD, IE, vol. 119, no. 2, doi:10.1016/J.JEP.2008.07.015, ISSN 0378-8741, (20080926), pages 252 - 258, (20080723), XP025399344 [A] 1-12 * the whole document * DOI: http://dx.doi.org/10.1016/j.jep.2008.07.015 | [A] - WENG ET AL, "Theanaphthoquinone inhibits fatty acid synthase expression in EGF-stimulated human breast cancer cells via the regulation of EGFR/ErbB-2 signaling", TOXICOLOGY AND APPLIED PHARMACOLOGY, ACADEMIC PRESS, AMSTERDAM, NL, (20070201), vol. 218, no. 2, doi:10.1016/J.TAAP.2006.10.021, ISSN 0041-008X, pages 107 - 118, XP005737697 [A] 1-12 * the whole document * DOI: http://dx.doi.org/10.1016/j.taap.2006.10.021 | International search | [X]US2007004713 (BARLAAM BERNARD [FR], et al); | [Y]US2007043043 (CHEN DIZHONG [SG], et al) |