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Extract from the Register of European Patents

EP About this file: EP2392583

EP2392583 - RNAi modulation of Aha and therapeutic uses thereof [Right-click to bookmark this link]
StatusThe application is deemed to be withdrawn
Status updated on  08.11.2013
Database last updated on 20.09.2024
Most recent event   Tooltip08.11.2013Application deemed to be withdrawnpublished on 11.12.2013  [2013/50]
Applicant(s)For all designated states
Alnylam Europe AG.
300 Third Street
Cambridge, MA 02142 / US
For all designated states
The Scripps Research Institute
Mail Drop TPC-8 10550 North Torrey Pines Road
La Jolla CA 92037 / US
[2011/49]
Inventor(s)01 / Constien, Rainer
c/o Alnylam Pharmaceuticals Inc.
300 Third Street
Cambridge, MA 02142 / US
02 / Bramlage, Birgit
c/o Alnylam Pharmaceuticals Inc.
300 Third Street
Cambridge, MA 02142 / US
03 / Tan, Pamela
c/o Alnylam Pharmaceuticals Inc.
300 Third Street
Cambridge, MA 02142 / US
04 / Vornlocher, Hans-Peter
c/o Alnylam Pharmaceuticals Inc.
300 Third Street
Cambridge, MA 02142 / US
05 / Balch, William
4037 Grayson Drive
San Diego, CA 92130 / US
 [2011/49]
Representative(s)Vossius & Partner Patentanwälte Rechtsanwälte mbB
Siebertstrasse 3
81675 München / DE
[N/P]
Former [2011/49]Vossius & Partner
Siebertstrasse 4
81675 München / DE
Application number, filing date11006765.918.05.2007
[2011/49]
Priority number, dateUS20060801840P19.05.2006         Original published format: US 801840 P
[2011/49]
Filing languageEN
Procedural languageEN
PublicationType: A1 Application with search report 
No.:EP2392583
Date:07.12.2011
Language:EN
[2011/49]
Search report(s)(Supplementary) European search report - dispatched on:EP04.11.2011
ClassificationIPC:C07H21/04, C12N15/113
[2011/49]
CPC:
C12N15/113 (EP,US); A61P1/18 (EP); A61P11/00 (EP);
A61P35/00 (EP); A61P35/02 (EP); A61P35/04 (EP);
A61P43/00 (EP); C12N2310/14 (EP,US); C12N2310/3515 (EP,US) (-)
Designated contracting statesAT,   BE,   BG,   CH,   CY,   CZ,   DE,   DK,   EE,   ES,   FI,   FR,   GB,   GR,   HU,   IE,   IS,   IT,   LI,   LT,   LU,   LV,   MC,   MT,   NL,   PL,   PT,   RO,   SE,   SI,   SK,   TR [2011/49]
TitleGerman:RNAi-Modulation von AHA und therapeutische Verwendungen davon[2011/49]
English:RNAi modulation of Aha and therapeutic uses thereof[2011/49]
French:Modulation ARNi de AHAS et utilisations thérapeutiques associées[2011/49]
Examination procedure13.09.2011Examination requested  [2011/49]
24.05.2012Amendment by applicant (claims and/or description)
05.02.2013Communication of intention to grant the patent
18.06.2013Application deemed to be withdrawn, date of legal effect  [2013/50]
23.07.2013Despatch of communication that the application is deemed to be withdrawn, reason: fee for grant / fee for printing not paid in time  [2013/50]
Parent application(s)   TooltipEP07797577.9  / EP2023937
Fees paidRenewal fee
14.12.2011Renewal fee patent year 03
14.12.2011Renewal fee patent year 04
25.10.2011Renewal fee patent year 05
25.05.2012Renewal fee patent year 06
Penalty fee
Additional fee for renewal fee
31.05.201307   M06   Not yet paid
Opt-out from the exclusive  Tooltip
competence of the Unified
Patent Court
See the Register of the Unified Patent Court for opt-out data
Responsibility for the accuracy, completeness or quality of the data displayed under the link provided lies entirely with the Unified Patent Court.
Documents cited:Search[A]WO03070918  (RIBOZYME PHARM INC [US], et al) [A] 1-12 * page 8, paragraph 2 * * page 19, paragraph 2 * * page 26, paragraph 1 - page 28, paragraph 1 * * page 97, paragraph 6 *;
 [A]WO2005044981  (SIRNA THERAPEUTICS INC [US], et al) [A] 1-12 * page 18, paragraph 1 * * page 34, lines 12-26 * * page 52, line 1 - page 53, line 21 * * page 126, paragraph 1 * * page 149, paragraph 1 * * page 215, line 54 *;
 [A]  - HARST ANJA ET AL, "Aha1 competes with Hop, p50 and p23 for binding to the molecular chaperone Hsp90 and contributes to kinase and hormone receptor activation.", THE BIOCHEMICAL JOURNAL 1 MAY 2005, (20050501), vol. 387, no. Pt 3, ISSN 1470-8728, pages 789 - 796, XP002545499 [A] 1-12 * figure 6 * * page 790, column R, paragraph 2 *
 [A]  - HARBORTH J ET AL, "Sequence, chemical, and structural variation of small interfering RNAs and short hairpin RNAs and the effect on mammalian gene silencing", ANTISENSE & NUCLEIC ACID DRUG DEVELOPMENT, MARY ANN LIEBERT, INC., NEW YORK, US, (20030401), vol. 13, no. 2, ISSN 1087-2906, pages 83 - 105, XP002284355 [A] 1-12 * figures 7,8 *

DOI:   http://dx.doi.org/10.1089/108729003321629638
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