blank Quick help
blank Maintenance news

Scheduled maintenance

Regular maintenance outages:
between 05.00 and 05.15 hrs CET (Monday to Sunday).

Other outages
Availability

2022.02.11

More...
blank News flashes

News Flashes

New version of the European Patent Register – SPC proceedings information in the Unitary Patent Register.

2024-07-24

More...
blank Related links

Release notes
European Patent Register Assistant
European Patent Register Resource Book
European Patent Register – pocket guide
FAQ - European Patent Register
Federated Register (Flyer)
Global Dossier (Flyer)
Register events
Deep link coverage
Federated Register content
The Patent Information Tour
Fair use charter

Extract from the Register of European Patents

EP About this file: EP2400008

EP2400008 - In tumours differentially expressed gene products and use of the same [Right-click to bookmark this link]
StatusThe application is deemed to be withdrawn
Status updated on  27.09.2019
Database last updated on 03.10.2024
FormerGrant of patent is intended
Status updated on  18.12.2018
FormerExamination is in progress
Status updated on  02.12.2016
Most recent event   Tooltip27.09.2019Application deemed to be withdrawnpublished on 30.10.2019  [2019/44]
Applicant(s)For all designated states
Ganymed Pharmaceuticals GmbH
An der Goldgrube 12
55131 Mainz / DE
[2018/42]
Former [2015/23]For all designated states
Ganymed Pharmaceuticals AG
An der Goldgrube 12
55131 Mainz / DE
Former [2011/52]For all designated states
Ganymed Pharmaceuticals AG
Freiligrathstrasse 12
55131 Mainz / DE
Inventor(s)01 / Sahin, Ugur
Philipp-von-Zabern-Platz 1
55116 Mainz / DE
02 / Türeci, Özlem
Philipp-von-Zabern-Platz 1
55116 Mainz / DE
03 / Koslowski, Michael
Am Ried 23
85764 Oberschleißheim / DE
 [2012/51]
Former [2011/52]01 / Sahin, Ugur
Philipp-von-Zabern-Platz 1
55116 Mainz / DE
02 / Türeci, Özlem
Philipp-von-Zabern-Platz 1
55116 Mainz / DE
03 / Koslowski, Michael
Autogenstrasse 50
65933 Frankfurt / DE
Representative(s)Schnappauf, Georg, et al
ZSP Patentanwälte PartG mbB
Hansastraße 32
80686 München / DE
[N/P]
Former [2011/52]Schnappauf, Georg, et al
Dr. Volker Vossius
Patent- und Rechtsanwaltskanzlei
Geibelstrasse 6
81679 München / DE
Application number, filing date11007319.421.11.2003
[2011/52]
Priority number, dateDE2002105460122.11.2002         Original published format: DE 10254601
[2011/52]
Filing languageDE
Procedural languageDE
PublicationType: A2 Application without search report 
No.:EP2400008
Date:28.12.2011
Language:DE
[2011/52]
Type: A3 Search report 
No.:EP2400008
Date:25.07.2012
Language:DE
[2012/30]
Search report(s)(Supplementary) European search report - dispatched on:EP27.06.2012
ClassificationIPC:C12N15/11, A61K39/395, C12N5/10, C07K14/47, C07K16/30, C07K16/32, A61K48/00, C07K16/18, G01N33/574
[2012/15]
CPC:
C07K14/47 (EP,CN,KR,US); A61K39/39558 (KR); A61K48/005 (CN);
C07K16/3076 (US); A61K39/0011 (CN); A61K39/395 (CN);
A61K47/549 (US); A61P1/04 (EP); A61P1/18 (EP);
A61P11/00 (EP); A61P13/08 (EP); A61P13/12 (EP);
A61P15/00 (EP); A61P17/00 (EP); A61P35/00 (EP,KR);
A61P43/00 (EP); C07K16/18 (EP,CN,KR,US); C07K16/30 (EP,KR,US);
C07K16/3023 (EP,US); C07K16/3046 (EP,US); C12Q1/6886 (CN);
G01N33/5011 (CN); G01N33/5017 (CN); G01N33/57407 (CN);
G01N33/57484 (EP,CN,US); A61K2039/505 (EP,KR,US); C07K2317/30 (KR,US);
C07K2317/34 (EP,KR,US); C12N2503/02 (CN); C12Q2600/136 (CN);
C12Q2600/158 (CN); G01N2500/10 (CN) (-)
Former IPC [2011/52]C12N15/11, A61K39/395, C12N5/10, C07K14/47, C07K16/30, C07K16/32, A61K48/00
Designated contracting statesAT,   BE,   BG,   CH,   CY,   CZ,   DE,   DK,   EE,   ES,   FI,   FR,   GB,   GR,   HU,   IE,   IT,   LI,   LU,   MC,   NL,   PT,   RO,   SE,   SI,   SK,   TR [2011/52]
Extension statesAL24.01.2013
LT24.01.2013
LV24.01.2013
MK24.01.2013
TitleGerman:Differentiell in Tumoren exprimierte Genprodukte und deren Verwendung[2011/52]
English:In tumours differentially expressed gene products and use of the same[2011/52]
French:Produits géniques d'expression différentielle dans les tumeurs et leur utilisation[2011/52]
Examination procedure24.01.2013Amendment by applicant (claims and/or description)
24.01.2013Examination requested  [2013/10]
02.10.2013Despatch of a communication from the examining division (Time limit: M06)
10.04.2014Reply to a communication from the examining division
21.05.2015Despatch of a communication from the examining division (Time limit: M06)
10.03.2016Reply to a communication from the examining division
30.08.2016Despatch of a communication from the examining division (Time limit: M06)
07.03.2017Reply to a communication from the examining division
31.03.2017Despatch of a communication from the examining division (Time limit: M06)
17.01.2018Reply to a communication from the examining division
19.12.2018Communication of intention to grant the patent
30.04.2019Application deemed to be withdrawn, date of legal effect  [2019/44]
06.06.2019Despatch of communication that the application is deemed to be withdrawn, reason: fee for grant / fee for printing not paid in time  [2019/44]
Parent application(s)   TooltipEP03773719.4  / EP1563068
Divisional application(s)The date of the Examining Division's first communication in respect of the earliest application for which a communication has been issued (EP20030773719) is  08.09.2009
Request for further processing for:The application is deemed to be withdrawn due to failure to reply to the examination report
17.01.2018Request for further processing filed
17.01.2018Full payment received (date of receipt of payment)
Request granted
15.03.2018Decision despatched
The application is deemed to be withdrawn due to failure to reply to the examination report
10.03.2016Request for further processing filed
10.03.2016Full payment received (date of receipt of payment)
Request granted
22.03.2016Decision despatched
Fees paidRenewal fee
22.12.2011Renewal fee patent year 03
22.12.2011Renewal fee patent year 04
22.12.2011Renewal fee patent year 05
22.12.2011Renewal fee patent year 06
22.12.2011Renewal fee patent year 07
22.12.2011Renewal fee patent year 08
22.12.2011Renewal fee patent year 09
28.11.2012Renewal fee patent year 10
29.11.2013Renewal fee patent year 11
27.11.2014Renewal fee patent year 12
27.11.2015Renewal fee patent year 13
29.11.2016Renewal fee patent year 14
30.11.2017Renewal fee patent year 15
Penalty fee
Additional fee for renewal fee
30.11.201816   M06   Not yet paid
Opt-out from the exclusive  Tooltip
competence of the Unified
Patent Court		 See the Register of the Unified Patent Court for opt-out data
Responsibility for the accuracy, completeness or quality of the data displayed under the link provided lies entirely with the Unified Patent Court.
Documents cited:Search[A]WO0127257  (UNIV ARKANSAS [US]) [A] 1-16 * the whole document *;
 [XI]WO0154708  (HUMAN GENOME SCIENCES INC [US], et al) [X] 1-9,14-16 * page 8, line 8 ff; sequence 123 * [I] 1-16;
 [A]WO0162920  (CORIXA CORP [US]) [A] 1-16 * the whole document *;
 [XI]WO0168848  (GENENTECH INC [US], et al) [X] 1-9,13-16 * the whole document * [I] 1-16;
 [XI]WO0218576  (DIADEXUS INC [US], et al) [X] 1-9,13-16 * claims 1-16; sequence 76 * * claim 2 * [I] 1-16;
 [A]WO0222684  (INCYTE GENOMICS INC [US], et al) [A] 1-16* the whole document *;
 [A]WO0246224  (DIADEXUS INC [US], et al) [A] 1-16 * the whole document *;
 [XI]US2002119130  (EATON DAN L [US], et al) [X] 1-9,12-16 * example 18; sequences 117, 118 * [I] 1-16;
 [A]WO02074237  (CORIXA CORP [US], et al) [A] 1-16 * the whole document *;
 [XI]  - NIIMI T ET AL, "claudin-18, a novel downstream target gene for the T/EBP/NKX2.1 homeodomain transcription factor, encodes lung- and stomach-specific isoforms through alternative splicing.", MOLECULAR AND CELLULAR BIOLOGY NOV 2001, (200111), vol. 21, no. 21, ISSN 0270-7306, pages 7380 - 7390, XP002433561 [X] 1,6,9,15 * the whole document * [I] 1-16

DOI:   http://dx.doi.org/10.1128/MCB.21.21.7380-7390.2001
 [A]  - REITER Y ET AL, "peptide-specific killing of antigen-presenting cells by a recombinant antibody-toxin fusion protein targeted to major histocompatibility complex/peptide class I complexes with T cell receptor-like specificity", PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF USA, NATIONAL ACADEMY OF SCIENCE. WASHINGTON, US, (199704), vol. 94, ISSN 0027-8424, pages 4631 - 4636, XP002967291 [A] 1-16 * abstract *

DOI:   http://dx.doi.org/10.1073/pnas.94.9.4631
 [A]  - ENGBERG J ET AL, "RECOMBINANT ANTIBODIES WITH THE ANTIGEN-SPECIFIC, MHC RESTRICTED SPECIFICITY OF T CELLS: NOVEL REAGENTS FOR BASIC AND CLINICAL INVESTIGATIONS AND IMMUNOTHERAPY", IMMUNOTECHNOLOGY, XX, XX, (199903), vol. 4, pages 273 - 278, XP000991083 [A] 1-16 * abstract *

DOI:   http://dx.doi.org/10.1016/S1380-2933(98)00017-7
 [A]  - RUDOLPH M G ET AL, "The specificity of TCR/pMHC interaction", CURRENT OPINION IN IMMUNOLOGY, CURRENT BIOLOGY LTD, (20020201), vol. 14, no. 1, ISSN 0952-7915, pages 52 - 65, XP004332735 [A] 1-16 * the whole document *

DOI:   http://dx.doi.org/10.1016/S0952-7915(01)00298-9
by applicantWO9204381
 WO9633265
 WO9633739
    - PARDOLL, NAT. MED, (1998), vol. 4, page 525.31
    - VAN DER BRUGGEN ET AL., SCIENCE, (1991), vol. 254, pages 1643 - 1647
    - SAHIN ET AL., CURR. OPIN. IMMUNOL., (1997), vol. 9, pages 709 - 716
    - SCHMITT ET AL., NUCLEIC ACIDS RES., (1999), vol. 27, pages 4251 - 4260
    - VASMATZIS ET AL., PROC. NATL. AEAD. SEI. USA, (1998), vol. 95, pages 300 - 304
    - SCHEURLE ET AL., CANCER RES., (2000), vol. 60, pages 4037 - 4043
    - DURAND, SETA, CLIN. CHEM., (2000), vol. 46, pages 795 - 805
    - HAKOMORI, CANCER RES., (1996), vol. 56, pages 5309 - 5318
    - Current Protocols in Molecular Biology, JOHN WILEY & SONS, INC.
    - ANDERSON ET AL., J. IMMUNOL., (1989), vol. 143, pages 1899 - 1904
    - GARDSVOLL, J. IMMUNOL. METHODS, (2000), vol. 234, pages 107 - 116
    - KAYYEM ET AL., EUR. J. BIOCHEM., (1992), vol. 208, pages 1 - 8
    - SPILLER ET AL., J. IMMUNOL. METHODS, (1999), vol. 224, pages 51 - 60
    - PHILIP SHEPHERD, CHRISTOPHER DEAN, MONOCLONAL ANTIBODIES: A PRACTICAL APPROACH
    - Antibodies: A Laboratory Manual
    - EDWARD HARLOW, DAVID LANE, Using Antibodies: A Laboratory Manual: Portable Protocol NO
    - AZORSA ET AL., J IMMUNOL. METHODS, (1999), vol. 229, pages 35 - 48
    - ANDERSON ET AL., J IMMUNOL., (1989), vol. 143, pages 1899 - 1904
    - GARDSVOLL, J IMMUNOL. METHODS., (2000), vol. 234, pages 107 - 116
    - ED HARLOW, DAVID LANE, Antibodies: A Laboratory Manual
    - DE WILDT ET AL., J. IMMUNOL. METHODS, (1997), vol. 207, pages 61 - 67
    - ALTMAN ET AL., SCIENCE, (1996), vol. 274, pages 94 - 96
    - DUNBAR ET AL., CURR. BIOL., (1998), vol. 8, pages 413 - 416
    - GREENBERG, J. IMMUNOL., (1986), vol. 136, no. 5, page 1917
    - RIDDEL ET AL., SCIENCE, (1992), vol. 257, page 238
    - LYNCH ET AL., EUR. J. IMMUNOL., (1991), vol. 21, pages 1403 - 1410
    - KAST ET AL., CELL, (1989), vol. 59, pages 603 - 614
    - STANISLAWSKI ET AL., NAT IMMUNOL., (2001), vol. 2, pages 962 - 970
    - KESSELS ET AL., NAT IMMUNOL., (2001), vol. 2, pages 957 - 961
    - OSSENDORP ET AL., IMMUNOL LETT., (2000), vol. 74, pages 75 - 79
    - OSSENDORP ET AL., J. EXP. MED., (1998), vol. 187, pages 693 - 702
    - MALOY ET AL., PROC NATL ACAD SCI USA, (2001), vol. 98, pages 3299 - 3303
    - KEOGH ET AL., JLMMUNOL., (2001), vol. 167, pages 787 - 796
    - APPELLA ET AL., BIOMED PEPT PROTEINS NUCLEIC ACIDS, (1995), vol. 1, pages 177 - 184
    - WENTWORTH ET AL., MOL IMMUNOL., (1995), vol. 32, pages 603 - 612
    - SO ET AL., MOL. CELLS, (1997), vol. 7, pages 178 - 186
    - KREIG ET AL., NATURE, (1995), vol. 374, pages 546 - 549
    - SCIENCE, (1995), vol. 268, pages 1432 - 1434
    - ZHENG, P. ET AL., PROC. NATL. ACAD. SCI. USA, (1998), vol. 95, no. 11, pages 6284 - 6289
    - GAJEWSKI ET AL., J IMMUNOL., (1995), vol. 154, pages 5637 - 5648
    - RIDGE ET AL., NATURE, (1998), vol. 393, page 474
    - BENNETT ET AL., NATURE, (1998), vol. 393, page 478
    - SCHÖNBERGER ET AL., NATURE, (1998), vol. 393, page 480
    - SAMBROOK ET AL., Molecular Cloning: A Laboratory Manual, COLD SPRING HARBOR LABORATORY PRESS
    - WHEELER ET AL., NUCLEIC ACIDS RESEARCH, (2000), vol. 28, pages 10 - 14
    - ADAMS ET AL., SCIENCE, (1991), vol. 252, page 1651
    - HILLIER ET AL., GENOME RESEARCH, (1996), vol. 6, pages 807 - 828
    - PENNISI, SCIENCE, (1997), vol. 276, pages 1023 - 1024
    - CHOMCZYNSKI, SACCHI, ANAL. BIOCHEM., (1987), vol. 162, pages 156 - 159
    - LEMOINE ET AL., METHODS MOL. BIOL., (1997), vol. 75, pages 441 - 447
    - SHI ET AL., J. HISTOCHEM. CYTOCHEM., (1991), vol. 39, pages 741 - 748
    - SHIN ET AL., LAB. INVEST., (1991), vol. 64, pages 693 - 702
    - EDWARD HARLOW, DAVID LANE, Using Antibodies : A Laboratory Manual : Portable Protocol NO.
    - Current Protocols in Molecular Biology, JOHN WILEY & SONS LTD., WILEY INTERSCIENCE
    - JUNG ET AL., MOL CELLS, (2001), vol. 12, pages 41 - 49
    - KASINRERK ET AL., HYBRID HYBRIDOMICS, (2002), vol. 21, pages 287 - 293
    - Current Protocols in Proteinchemistry, JOHN WILEY & SONS LTD., WILEY INTERSCIENCE
    - LEMOINE ET AL., METHODS MOL. BIOL, (1997), vol. 75, pages 441 - 447
    - O'DOWD ET AL., GENOMICS, (1998), vol. 47, pages 310 - 313
    - HORIKAWA Y, ODA N, COX NJ, LI X, ORHO-MELANDER M, HARA M, HINOKIO Y, LINDNER TH, MASHIMA H, SCHWARZ PE, NAT GENET., (200010), vol. 26, no. 2, pages 163 - 175
    - PARK ET AL., CANCER EPIDEMIOL BIOMARKERS PREV., (2002), vol. 11, pages 739 - 744
    - PEARLMAN ET AL., DIG. DIS. SCI., (2000), vol. 45, pages 298 - 305
    - TREMBLAY ET AL., MOL CELL BIOCHEM, vol. 230, page 31
    - NIIMI ET AL., AM J HUM GENET, (2002), vol. 70, pages 718 - 725
    - NIIMI, KOLLEGEN, MOL. CELL. BIOL., (2001), vol. 21, pages 7380 - 7390
    - RADER C, RITTER G, NATHAN S, ELIA M, GOUT I, JUNGBLUTH AA, COHEN LS, WELT S, OLD LJ, BARBAS CF 3RD, "The rabbit antibody repertoire as a novel source for the generation of therapeutic human antibodies", J BIOL CHEM., (20000505), vol. 275, no. 18, pages 13668 - 13676
    - LEE ET AL., GENOMICS, vol. 70, pages 354 - 363
    - GRUBER ET AL., GENOMICS, (1998), vol. 54, pages 200 - 214
    - BINGLE, BINGLE, BIOCHIM BIOPHYS ACTA, (2000), vol. 1493, pages 363 - 367
    - LOHI ET AL., J BIOL CHEM, (2002), vol. 277, pages 14246 - 14254
The EPO accepts no responsibility for the accuracy of data originating from other authorities; in particular, it does not guarantee that it is complete, up to date or fit for specific purposes.