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EP2385125
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EP About this file: EP2385125
| EP2385125 - Method of producing biologically active vitamin K dependent proteins by recombinant methods [Right-click to bookmark this link] | Status | The application is deemed to be withdrawn Status updated on 07.07.2017 Database last updated on 16.11.2024 | |
| Former | Examination is in progress Status updated on 03.01.2017 | Most recent event Tooltip | 07.07.2017 | Application deemed to be withdrawn | published on 09.08.2017 [2017/32] | Applicant(s) | For all designated states CNJ HOLDINGS, INC 155 Innovation Drive Winnipeg, MB R3T 5Y3 / CA | For all designated states University of North Carolina at Chapel Hill Chapel Hill, NC 27599 / US | [2013/46] |
| Former [2013/25] | For all designated states Cangene Corporation 115 Innovation Drive Winnipeg, Manitoba R3T 5Y3 / CA | ||
| For all designated states University of North Carolina at Chapel Hill Chapel Hill, NC 27599 / US | |||
| Former [2011/45] | For all designated states Inspiration Biopharmaceuticals, Inc. 28202 Cabot Road, Suite 300 Laguna Niguel, CA 92677 / US | ||
| For all designated states University of North Carolina at Chapel Hill Chapel Hill, NC 27599 / US | Inventor(s) | 01 /
Drohan, William N. 8300 Botsford Ct. Springfield, VA 22152 / US | 02 /
Griffith, Michael J. 28761 Via Buena Vista San Juan Capistrano, CA 92675 / US | 03 /
Taylor, John R. 45 E. 89th Street, Apt. 40E New York, NY 10128 / US | 04 /
Stafford, Darrel W. 300 Rainbow Drive Carrboro, NC 27599 / US | [2012/46] |
| Former [2011/45] | 01 /
Drohan, William N. 21505 Sun Garden Court Germantown, MD 20876 / US | ||
| 02 /
Griffith, Michael J. 28761 Via Buena Vista San Juan Capistrano, CA 92675 / US | |||
| 03 /
Taylor, John R. 45 E. 89th Street, Apt. 40E New York, NY 10128 / US | |||
| 04 /
Stafford, Darrel W. 300 Rainbow Drive Carrboro, NC 27599 / US | Representative(s) | Gill Jennings & Every LLP The Broadgate Tower 20 Primrose Street London EC2A 2ES / GB | [N/P] |
| Former [2013/25] | Gates, Marie Christina Esther, et al Tomkins & Co. 5 Dartmouth Road Dublin 6 / IE | ||
| Former [2012/33] | Pallard, Caroline Chantal Patricia, et al Nederlandsch Octrooibureau P.O. Box 29720 2502 LS Den Haag / NL | ||
| Former [2011/45] | Dannenberger, Oliver Andre, et al Abitz & Partner Hörselbergstrasse 5 81677 Munich / DE | Application number, filing date | 11157194.9 | 21.12.2006 | [2011/45] | Priority number, date | US20050752642P | 21.12.2005 Original published format: US 752642 P | [2011/45] | Filing language | EN | Procedural language | EN | Publication | Type: | A2 Application without search report | No.: | EP2385125 | Date: | 09.11.2011 | Language: | EN | [2011/45] | Type: | A3 Search report | No.: | EP2385125 | Date: | 11.04.2012 | Language: | EN | [2012/15] | Search report(s) | (Supplementary) European search report - dispatched on: | EP | 08.03.2012 | Classification | IPC: | C12N15/57, C12P21/02 | [2011/45] | CPC: |
C12N9/6429 (EP,US);
C12P21/00 (US);
A61P7/04 (EP);
C12N9/0006 (EP,US);
C12N9/6424 (EP,US);
C12N9/6437 (EP,US);
C12N9/644 (EP,US);
C12N9/647 (EP,US);
C12N9/88 (EP,US);
C12Y304/21005 (EP,US);
C12Y304/21022 (EP,US);
C12Y101/04001 (EP,US);
| Designated contracting states | AT, BE, BG, CH, CY, CZ, DE, DK, EE, ES, FI, FR, GB, GR, HU, IE, IS, IT, LI, LT, LU, LV, MC, NL, PL, PT, RO, SE, SI, SK, TR [2011/45] | Title | German: | Verfahren zur Herstellung von Biologisch aktiven Vitamin K-abhängigen Proteinen aus rekombinanten Verfahren | [2011/45] | English: | Method of producing biologically active vitamin K dependent proteins by recombinant methods | [2011/45] | French: | Procédé de production de protéines dépendantes de la vitamine K, biologiquement actives par des procédés de recombinaison | [2011/45] | Examination procedure | 11.10.2012 | Examination requested [2012/47] | 16.01.2013 | Amendment by applicant (claims and/or description) | 09.04.2013 | Despatch of a communication from the examining division (Time limit: M06) | 17.10.2013 | Reply to a communication from the examining division | 21.07.2014 | Despatch of a communication from the examining division (Time limit: M06) | 30.01.2015 | Reply to a communication from the examining division | 28.01.2016 | Despatch of a communication from the examining division (Time limit: M06) | 08.08.2016 | Reply to a communication from the examining division | 17.08.2016 | Despatch of a communication from the examining division (Time limit: M06) | 28.02.2017 | Application deemed to be withdrawn, date of legal effect [2017/32] | 29.03.2017 | Despatch of communication that the application is deemed to be withdrawn, reason: reply to the communication from the examining division not received in time [2017/32] | Parent application(s) Tooltip | EP06848864.2 / EP1969127 | Divisional application(s) | The date of the Examining Division's first communication in respect of the earliest application for which a communication has been issued (EP20060848864) is 23.02.2009 | Request for further processing for: | The application is deemed to be withdrawn due to failure to reply to the Extended European Search Report/Written Opinion of the International Searching Authority/International Preliminary Examination Report/Supplementary international search report/Supplementary European search report | 16.01.2013 | Request for further processing filed | 16.01.2013 | Full payment received (date of receipt of payment) Request granted | 29.01.2013 | Decision despatched | Fees paid | Renewal fee | 07.03.2011 | Renewal fee patent year 03 | 07.03.2011 | Renewal fee patent year 04 | 07.03.2011 | Renewal fee patent year 05 | 12.12.2011 | Renewal fee patent year 06 | 12.02.2013 | Renewal fee patent year 07 | 27.12.2013 | Renewal fee patent year 08 | 29.12.2014 | Renewal fee patent year 09 | 28.12.2015 | Renewal fee patent year 10 | 13.12.2016 | Renewal fee patent year 11 | Penalty fee | Additional fee for renewal fee | 31.12.2012 | 07 M06 Fee paid on 12.02.2013 |
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| Responsibility for the accuracy, completeness or quality of the data displayed under the link provided lies entirely with the Unified Patent Court. | Documents cited: | Search | [X]WO9209698 (GENETICS INST [US], et al) [X] 11,12,14,15 * example 6 * * page 21, line 11 ** page 29, line 1; claims 10,24,43-48,50-52 *; | [A]WO9849289 (ICOS CORP [US]) [A] 1-10 * the whole document *; | [XY]WO2005038019 (ASTRAZENECA AB [SE], et al) [X] 9,11,12,14,15 * examples 1,2,4 * * page 2, line 1 - line 5 * * page 7, line 16 - page 8, line 5; table 1 * * page 10, line 16 - line 28 * * page 16, line 14 * * page 18, line 24 - line 28 * * examples 6,7; claims 5,32-35 * [Y] 13; | [XP]WO2006067116 (NOVO NORDISK HEALTHCARE AG [CH], et al) [XP] 11,12,14,15 * example 3; claims 1-15 * * page 6, line 1 - line 2 * * page 17, line 17 - line 31 *; | [XP]WO2006089613 (BAXTER INT [US], et al) [XP] 11,12,14,15 * examples 1-4; claims 1-12 *; | [XY] - ROTH DAVID A ET AL, "Human recombinant factor IX: Safety and efficacy studies in hemophilia B patients previously treated with plasma-derived factor IX concentrates", BLOOD, (20011215), vol. 98, no. 13, ISSN 0006-4971, pages 3600 - 3606, XP002442457 [X] 9-12,14,15 * abstract * * page 3601, column R, paragraph L - page 3602, column L, paragraph 1 * [Y] 13 DOI: http://dx.doi.org/10.1182/blood.V98.13.3600 | [XY] - KAUFMAN R J ET AL, "EXPRESSION PURIFICATION AND CHARACTERIZATION OF RECOMBINANT GAMMA CARBOXYLATED FACTOR-IX SYNTHESIZED IN CHINESE HAMSTER OVARY CELLS", JOURNAL OF BIOLOGICAL CHEMISTRY.(MICROFILMS), AMERICAN SOCIETY OF BIOLOGICAL CHEMISTS, BALTIMORE, MD, US, (19860725), vol. 261, no. 21, pages 9622 - 9628, XP002375183 [X] 9,11,12,14,15 * the whole document * [Y] 1-8 | [Y] - RUNNING DEER J ET AL, "High-level expression of proteins in mammalian cells using transcription regulatory sequences from the Chinese hamster EF-1alpha gene", BIOTECHNOLOGY PROGRESS, AMERICAN INSTITUTE OF CHEMICAL ENGINEERS, US, (20040501), vol. 20, no. 3, doi:10.1021/BP034383R, ISSN 8756-7938, pages 880 - 889, XP002374790 [Y] 1-8,13 * the whole document * DOI: http://dx.doi.org/10.1021/bp034383r | [XY] - REHEMTULLA A ET AL, "In vitro and in vivo functional characterization of bovine vitamin K-dependent gamma-carboxylase expressed in Chinese hamster ovary cells", PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF USA, NATIONAL ACADEMY OF SCIENCE, WASHINGTON, DC, US, (199305), vol. 90, no. 10, ISSN 0027-8424, pages 4611 - 4615, XP002204115 [X] 9,11,12,14,15 * the whole document * [Y] 13 DOI: http://dx.doi.org/10.1073/pnas.90.10.4611 | [X] - WAJIH N ET AL, "Increased production of functional recombinant human clotting factor IX by baby hamster kidney cells engineered to overexpress VKORC1, the vitamin K 2,3-epoxide-reducing enzyme of the vitamin K cycle", JOURNAL OF BIOLOGICAL CHEMISTRY, AMERICAN SOCIETY OF BIOLOCHEMICAL BIOLOGISTS, BIRMINGHAM,, US, (20050719), vol. 280, no. 36, ISSN 0021-9258, pages 31603 - 31607, XP002375182 [X] 9 * the whole document * DOI: http://dx.doi.org/10.1074/jbc.M505373200 | [XY] - WASLEY L C ET AL, "PACE/FURIN CAN PROCESS THE VITAMIN K-DEPENDENT PRO-FACTOR IX PRECURSOR WITHIN THE SECRETORY PATHWAY", JOURNAL OF BIOLOGICAL CHEMISTRY, AMERICAN SOCIETY OF BIOLOCHEMICAL BIOLOGISTS, BIRMINGHAM,, US, (19930425), vol. 268, no. 12, ISSN 0021-9258, pages 8458 - 8465, XP001094106 [X] 9,11,12,14,15 * the whole document * [Y] 13 | by applicant | EP0073657 | US4399216 | WO8400560 | EP0117060 | EP0117058 | WO8505125 | EP0162782 | WO8505376 | US4599308 | EP0251874 | US4745051 | US4745057 | US4761371 | US4770999 | US4877729 | US4879224 | US4879236 | US4912038 | EP0373012 | US5268275 | US5460950 | US5714583 | US5888809 | US2003220247 | - BOND, M.; JANKOWSKI, M.; PATEL, H.; KARNIK, S.; STRAND, A.; XU, B. 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