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Extract from the Register of European Patents

EP About this file: EP2364988

EP2364988 - Stable NAD/NADH derivatives [Right-click to bookmark this link]
StatusNo opposition filed within time limit
Status updated on  02.01.2015
Database last updated on 16.11.2024
Most recent event   Tooltip20.05.2016Lapse of the patent in a contracting state
New state(s): BG		published on 22.06.2016  [2016/25]
Applicant(s)For:AT  BE  BG  CH  CY  CZ  DK  EE  ES  FI  FR  GB  GR  HU  IE  IS  IT  LI  LT  LU  LV  MC  NL  PL  PT  RO  SE  SI  SK  TR 
F. Hoffmann-La Roche AG
Grenzacherstrasse 124
4070 Basel / CH
For:DE 
Roche Diagnostics GmbH
Sandhofer Strasse 116
68305 Mannheim / DE
[2011/37]
Inventor(s)01 / Hoenes, Joachim
Rodauer Str. 50a
64673 Zwingenberg / DE
02 / Heindl, Dieter
Sternstr. 4
82396 Pähl / DE
03 / Horn, Carina
Frankenstr. 5
68647 Biblis / DE
04 / Gaessler-Dietsche, Claudia
Bismarckstr. 81
69198 Schriesheim / DE
 [2011/37]
Representative(s)Weiss, Wolfgang, et al
Weickmann & Weickmann
Patentanwälte PartmbB
Postfach 860 820
81635 München / DE
[N/P]
Former [2011/37]Weiss, Wolfgang, et al
Weickmann & Weickmann Postfach 860820
81635 München / DE
Application number, filing date11167471.928.07.2006
[2011/37]
Priority number, dateDE2005103546128.07.2005         Original published format: DE102005035461
[2011/37]
Filing languageDE
Procedural languageDE
PublicationType: A1 Application with search report 
No.:EP2364988
Date:14.09.2011
Language:DE
[2011/37]
Type: B1 Patent specification 
No.:EP2364988
Date:26.02.2014
Language:DE
[2014/09]
Search report(s)(Supplementary) European search report - dispatched on:EP17.08.2011
ClassificationIPC:C07H19/207, C07H23/00, C07H21/02, C07H19/213, C07H21/00, C12Q1/32
[2011/37]
CPC:
C12Q1/32 (EP,KR,US); G01N33/48 (KR); G01N33/533 (KR)
Designated contracting statesAT,   BE,   BG,   CH,   CY,   CZ,   DE,   DK,   EE,   ES,   FI,   FR,   GB,   GR,   HU,   IE,   IS,   IT,   LI,   LT,   LU,   LV,   MC,   NL,   PL,   PT,   RO,   SE,   SI,   SK,   TR [2011/37]
TitleGerman:Stabile NAD/NADH-Derivate[2011/37]
English:Stable NAD/NADH derivatives[2011/37]
French:Dérivés de NAD/NADH stables[2011/37]
Examination procedure25.05.2011Examination requested  [2011/37]
07.11.2011Amendment by applicant (claims and/or description)
12.09.2013Communication of intention to grant the patent
08.01.2014Fee for grant paid
08.01.2014Fee for publishing/printing paid
Parent application(s)   TooltipEP06776486.0  / EP1907408
Divisional application(s)The date of the Examining Division's first communication in respect of the earliest application for which a communication has been issued (EP20060776486) is  28.05.2009
Opposition(s)27.11.2014No opposition filed within time limit [2015/06]
Fees paidRenewal fee
25.05.2011Renewal fee patent year 03
25.05.2011Renewal fee patent year 04
25.05.2011Renewal fee patent year 05
25.05.2011Renewal fee patent year 06
10.07.2012Renewal fee patent year 07
08.07.2013Renewal fee patent year 08
Opt-out from the exclusive  Tooltip
competence of the Unified
Patent Court		 See the Register of the Unified Patent Court for opt-out data
Responsibility for the accuracy, completeness or quality of the data displayed under the link provided lies entirely with the Unified Patent Court.
Lapses during opposition  TooltipBG26.02.2014
CY26.02.2014
EE26.02.2014
LT26.02.2014
LV26.02.2014
MC26.02.2014
SI26.02.2014
IS26.06.2014
LU28.07.2014
[2016/25]
Former [2016/21]CY26.02.2014
EE26.02.2014
LT26.02.2014
LV26.02.2014
MC26.02.2014
SI26.02.2014
IS26.06.2014
LU28.07.2014
Former [2015/24]CY26.02.2014
EE26.02.2014
LT26.02.2014
LV26.02.2014
SI26.02.2014
IS26.06.2014
LU28.07.2014
Former [2015/13]CY26.02.2014
EE26.02.2014
LT26.02.2014
LV26.02.2014
IS26.06.2014
LU28.07.2014
Former [2014/48]CY26.02.2014
EE26.02.2014
LT26.02.2014
LV26.02.2014
IS26.06.2014
Former [2014/41]CY26.02.2014
LT26.02.2014
LV26.02.2014
IS26.06.2014
Former [2014/37]CY26.02.2014
LT26.02.2014
IS26.06.2014
Former [2014/36]LT26.02.2014
IS26.06.2014
Documents cited:Search[AD]US5801006  (KAUFMAN RICHARD A [US]) [AD] 1-16 * column 4, lines 56-67 * * claim 13 *;
 [AD]  - SLAMA J T ET AL, "CARBANICOTINAMIDE ADENINE DINUCLEOTIDE SYNTHESIS AND ENZYMOLOGICAL PROPERTIES OF A CARBOCYCLIC ANALOGUE OF OXIDIZED NAD", BIOCHEMISTRY, (1988), vol. 27, no. 1, ISSN 0006-2960, pages 183 - 193, XP002405653 [AD] 1-16 * page 184; compound 1 *

DOI:   http://dx.doi.org/10.1021/bi00401a028
 [AD]  - HUTCHINSON, EDWARD J. ET AL, "Synthesis of carbocyclic NAD+ containing a methylenebisphosphonate linkage for the investigation of ADP-ribosyl cyclase", CHEMICAL COMMUNICATIONS (CAMBRIDGE) , (24), 2765-2766 CODEN: CHCOFS; ISSN: 1359-7345, (1996), XP008070860 [AD] 1-16 * compounds 3B, 4 *
 [AD]  - ANDERSON B M, "ANALOGS OF PYRIDINE NUCLEOTIDE COENZYMES", PYRIDINE NUCLEOTIDE COENZYMES, (1982), pages 91 - 133, XP001085208 [AD] 1-16 * pages 99-103; compounds 2,3,5,8,9,17,20,41-44,83 *
 [A]  - MULLER-STEFFNER, HELENE ET AL, "Photodependent inhibition of bovine spleen NAD+ glycohydrolase by 8-azido carbocyclic analogs of NAD+", BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS , 228(1), 128-133 CODEN: BBRCA9; ISSN: 0006-291X, (1996), XP002405611 [A] 1-16 * page 130; compounds 1-4 *

DOI:   http://dx.doi.org/10.1006/bbrc.1996.1627
 [A]  - SLEATH P R ET AL, "PYRIDINE COENZYME ANALOGUES 3. SYNTHESIS OF THREE REDUCED NAD ANALOGUES CONTAINING A 2' DEOXY-2'-SUBSTITUTED NICOTINAMIDE ARABINOFURANOSYL MOIETY", JOURNAL OF ORGANIC CHEMISTRY, (1991), vol. 56, no. 11, ISSN 0022-3263, pages 3608 - 3613, XP002405612 [A] 1-16 * page 3610; compounds 10A-10C *

DOI:   http://dx.doi.org/10.1021/jo00011a029
by applicantWO0194370
 WO9833936
 US5801006
 WO0149247
 DE10221845
    - N.J. OPPENHEIMER, The Pyridine Nucieotide Coenzyms, ACADEMIC PRESS, (1982), pages 56 - 65
    - N.O. KAPLAN, J. BIOL. CHEM., (1956), vol. 221, page 823
    - J.T. SLAMA, BIOCHEMISTRY, (1989), vol. 27, page 183
    - BIOCHEMISTRY, (1989), vol. 28, page 7688
    - G.M. BLACKBURN, CHEM. COMM., (1996), page 2765
    - HURYN, DONNA M., SIUBOSKI, BARBARA C., TAM, STEVE Y., TODARO, LOUIS J., WEIGELE, MANFRED. TETRAHEDRON LETTERS, (1989), vol. 30, no. 46, pages 6259 - 62
    - BERES, J., SAGI, G., TOMOSKOZI, ., GRUBER, L., GULACSI, E., OTVOS, L., TETRAHEDRON LETTERS, (1988), vol. 29, no. 22, pages 2681 - 4
    - MORPHAT ET AL., J. AM. CHEM. SOC., (1961), vol. 83, pages 663 - 675
The EPO accepts no responsibility for the accuracy of data originating from other authorities; in particular, it does not guarantee that it is complete, up to date or fit for specific purposes.