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Extract from the Register of European Patents

EP About this file: EP2531177

EP2531177 - 4-[2-[[5-METHYL-1-(2-NAPHTHALENYL)-1H-PYRAZOL-3-YL]OXY]ETHYL]MORPHOLINE HYDROCHLORIDE POLYMORPHS AND SOLVATES [Right-click to bookmark this link]
Former [2012/50]4-[-2-[[5-METHYL-1-(2-NAPHTALENYL)-1H-PYRAZOL-3-YL]OXY]ETHYL]MORPHOLINE HYDROCHLORIDE POLYMORPHS AND SOLVATES
[2015/45]
StatusNo opposition filed within time limit
Status updated on  17.03.2017
Database last updated on 30.10.2024
Most recent event   Tooltip17.03.2017No opposition filed within time limitpublished on 19.04.2017  [2017/16]
Applicant(s)For all designated states
Laboratorios del Dr. Esteve, S.A.
Avda Mare de Deu de Montserrat 221
08041 Barcelona / ES
[2016/19]
Former [2012/50]For all designated states
Laboratorios del. Dr. Esteve, S.A.
Avda Mare de Deu de Montserrat 221
08041 Barcelona / ES
Inventor(s)01 / BERENGUER MAIMÓ, Ramón
Jovellanos 1
Izda. 4º 3ª
E-08001 Barcelona / ES
02 / MEDRANO RUPÉREZ, Jorge
C/Rosari 18, átic 2a
E-08921 Santa Colonia de Gramenet Barcelona / ES
03 / BENET BUCHHOLZ, Jordi
Plaza Romani 3 - Casa A
E-43893 Altafulla - Tarragona / ES
04 / PUIG FERNANDEZ, Laura
El Maquinista de la General 37 - 2A
E-50019 Zaragoza / ES
05 / PELLEJÀ PUXEU, Laia
Cigne 17 - Casa 6
E-43007 Tarragona / ES
 [2016/19]
Former [2012/50]01 / BERENGUER MAIMÓ, Ramón
Jovellanos 1
Izda. 4º 3ª
E-08001 Barcelona / ES
02 / MEDRANO RUPÉREZ, Jorge
C/Rosari 18, atic 2a
E-08921 Santa Colonia de Gramenet Barcelona / ES
03 / BENET BUCHHOLZ, Jordi
Plaza Romani 3 - Casa A
E-43893 Altafulla - Tarragona / ES
04 / PUIG FERNANDEZ, Laura
El Maquinista de la General 37 - 2A
E-50019 Zaragoza / ES
05 / PELLEJÀ PUXEU, Laia
Cigne 17 - Casa 6
E-43007 Tarragona / ES
Representative(s)ABG Intellectual Property Law, S.L.
Avenida de Burgos, 16D
Edificio Euromor
28036 Madrid / ES
[N/P]
Former [2012/50]ABG Patentes, S.L.
Avenida de Burgos, 16D
Edificio Euromor
28036 Madrid / ES
Application number, filing date11702056.004.02.2011
[2016/19]
WO2011EP51630
Priority number, dateEP2010038222609.08.2010         Original published format: EP 10382226
EP2010038202504.02.2010         Original published format: EP 10382025
[2012/50]
Filing languageEN
Procedural languageEN
PublicationType: A1 Application with search report
No.:WO2011095579
Date:11.08.2011
Language:EN
[2011/32]
Type: A1 Application with search report 
No.:EP2531177
Date:12.12.2012
Language:EN
The application published by WIPO in one of the EPO official languages on 11.08.2011 takes the place of the publication of the European patent application.
[2012/50]
Type: B1 Patent specification 
No.:EP2531177
Date:11.05.2016
Language:EN
[2016/19]
Type: B8 Corrected title page of specification 
No.:EP2531177
Date:12.10.2016
[2016/41]
Search report(s)International search report - published on:EP11.08.2011
ClassificationIPC:A61K9/16, A61K31/4152, C07D231/22, A61P25/00
[2012/50]
CPC:
C07D231/22 (EP,KR,US); C07D413/12 (KR); A61K31/4152 (EP,KR,US);
A61K31/4155 (EP,US); A61P25/00 (EP); A61P25/04 (EP);
A61P29/00 (EP); A61P43/00 (EP); A61P9/00 (EP) (-)
Designated contracting statesAL,   AT,   BE,   BG,   CH,   CY,   CZ,   DE,   DK,   EE,   ES,   FI,   FR,   GB,   GR,   HR,   HU,   IE,   IS,   IT,   LI,   LT,   LU,   LV,   MC,   MK,   MT,   NL,   NO,   PL,   PT,   RO,   RS,   SE,   SI,   SK,   SM,   TR [2012/50]
Extension statesBA30.08.2012
ME30.08.2012
TitleGerman:4-[2-[[5-METHYL-1-(2-NAPHTHALINYL)-1H-PYRAZOL-3-YL]OXY]ETHYL]MORPHOLIN HYDROCHLORID POLYMORPHE UND SOLVATE[2016/21]
English:4-[2-[[5-METHYL-1-(2-NAPHTHALENYL)-1H-PYRAZOL-3-YL]OXY]ETHYL]MORPHOLINE HYDROCHLORIDE POLYMORPHS AND SOLVATES[2016/21]
French:POLYMORPHES D'UN SEL DE CHLORHYDRATE DE 4-[2-[[5-METHYL-1-(2-NAPHTHALENYL)-1H-PYRAZOL-3-YL]OXY]ETHYL]MORPHOLINE ET DES SOLVATES[2016/21]
Former [2012/50]4-[-2-[[5-METHYL-1-(2-NAPHTHALENYL)-1H-PYRAZOL-3-YL]OXY]ETHYL]MORPHOLINHYDROCHLORIDPOLYMORPHE UND -SOLVATE
Former [2012/50]4-[-2-[[5-METHYL-1-(2-NAPHTALENYL)-1H-PYRAZOL-3-YL]OXY]ETHYL]MORPHOLINE HYDROCHLORIDE POLYMORPHS AND SOLVATES
Former [2012/50]POLYMORPHES ET SOLVATES DE CHLORHYDRATE DE 4-[-2-[[5-MÉTHYL-1-(2-NAPHTALÉNYL)-1H-PYRAZOL-3-YL]OXY]ÉTHYL]MORPHOLINE
Entry into regional phase30.08.2012National basic fee paid 
30.08.2012Designation fee(s) paid 
30.08.2012Examination fee paid 
Examination procedure30.08.2012Amendment by applicant (claims and/or description)
30.08.2012Examination requested  [2012/50]
18.11.2013Despatch of a communication from the examining division (Time limit: M04)
27.03.2014Reply to a communication from the examining division
29.09.2015Cancellation of oral proceeding that was planned for 11.11.2015
20.10.2015Communication of intention to grant the patent
11.11.2015Date of oral proceedings (cancelled)
15.02.2016Fee for grant paid
15.02.2016Fee for publishing/printing paid
15.02.2016Receipt of the translation of the claim(s)
11.04.2016Request for correction of the decision to grant filed
Divisional application(s)The date of the Examining Division's first communication in respect of the earliest application for which a communication has been issued is  18.11.2013
Opposition(s)14.02.2017No opposition filed within time limit [2017/16]
Fees paidRenewal fee
08.02.2013Renewal fee patent year 03
21.01.2014Renewal fee patent year 04
16.01.2015Renewal fee patent year 05
11.01.2016Renewal fee patent year 06
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Cited inInternational search[ID]WO2006021462  (ESTEVE LABOR DR [ES], et al) [ID] 1-18 * page 15 - page 16; example 61; claim 10 *;
 [I]EP2113501  (ESTEVE LABOR DR [ES]) [I] 1-18 * paragraph [0034]; claim 1 *;
 [A]  - LEE S ET AL, Handbook of Pharmaceutical Salts: Properties, Selection , and Use, Chapter 8 (Large-Scale Aspects of Salt Formation: Processing of Intermediates and Final Products, Chapter 12 (Monographs on Acids and Bases), HANDBOOK OF PHARMACEUTICAL SALTS : PROPERTIES, SELECTION, AND USE, ZÜRICH : VERL. HELVETICA CHIMICA ACTA ; WEINHEIM [U.A.] : WILEY-VCH, DE, PAGE(S) 191 - 192,211, (20020101), ISBN 978-3-906390-26-0, XP002548973 [A] 1-18 * page 192 * * page 211 - page 213 *
 [A]  - BERGE S M ET AL, "PHARMACEUTICAL SALTS", JOURNAL OF PHARMACEUTICAL SCIENCES, AMERICAN PHARMACEUTICAL ASSOCIATION, WASHINGTON, US, (19770101), vol. 66, no. 1, doi:DOI:10.1002/JPS.2600660104, ISSN 0022-3549, pages 1 - 19, XP002552191 [A] 1-18 * page 7, column r * * page 1, column r; table 1 *

DOI:   http://dx.doi.org/10.1002/jps.2600660104
by applicantWO2006021462
    - WALKER, J.M. ET AL., PHARMACOLOGICAL REVIEWS, (1990), vol. 42, page 355
    - SNYDER, S.H., LARGENT, B.L. J. NEUROPSYCHIATRY, (1989), vol. 1, page 7
    - QUIRION, R. ET AL., TRENDS PHARMACOL. SCI., (1992), vol. 13, pages 85 - 86
    - HANNER, M. ET AL., PROC. NATL. ACAD. SCI., (1996), vol. 93, pages 8072 - 8077
    - M. LANG ET AL., J. AM. CHEM. SOC., (2002), vol. 124, page 14834
    - C. PRICE ET AL., J. AM. CHEM. SOC., (2005), vol. 127, page 5512
The EPO accepts no responsibility for the accuracy of data originating from other authorities; in particular, it does not guarantee that it is complete, up to date or fit for specific purposes.