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Extract from the Register of European Patents

EP About this file: EP2545085

EP2545085 - Radiopaque, non-biodegradable, water-insoluble iodinated benzyl ethers of poly(vinyl alcohol), preparation method thereof, injectable embolizing compositions containing thereof and use thereof [Right-click to bookmark this link]
Former [2013/03]RADIOPAQUE, NON- BIODEGRADABLE, WATER - INSOLUBLE IODINATED BENZYL ETHERS OF POLY (VINYL ALCOHOL), PREPARATION METHOD THEREOF, INJECTABLE EMBOLIZING COMPOSITIONS CONTAINING THEREOF AND USE THEREOF
[2016/31]
StatusNo opposition filed within time limit
Status updated on  25.08.2017
Database last updated on 31.08.2024
Most recent event   Tooltip10.07.2020Lapse of the patent in a contracting state
New state(s): AL		published on 12.08.2020  [2020/33]
Applicant(s)For all designated states
Université Claude Bernard Lyon 1 (UCBL)
43 Boulevard du 11 Novembre 1918
69622 Villeurbanne Cedex / FR
For all designated states
Centre National de la Recherche Scientifique (C.N.R.S.)
3 rue Michel-Ange
75794 Paris Cedex 16 / FR
For all designated states
Antia Therapeutics S.A.
Normannenstrasse 8
3018 Bern / CH
[N/P]
Former [2016/42]For all designated states
Université Claude Bernard Lyon 1 (UCBL)
43 Boulevard du 11 Novembre 1918
69622 Villeurbanne Cedex / FR
For all designated states
Centre National de la Recherche Scientifique (CNRS)
3, rue Michel-Ange
75794 Paris Cedex 16 / FR
For all designated states
Antia Therapeutics S.A.
Normannenstrasse 8
3018 Bern / CH
Former [2013/03]For all designated states
Université Claude Bernard Lyon 1 (UCBL)
43 Boulevard du 11 Novembre 1918
69622 Villeurbanne Cedex / FR
For all designated states
Centre National de la Recherche Scientifique CNRS
3 rue Michel Ange
75794 Paris Cedex 16 / FR
For all designated states
Antia Therapeutics S.A.
Normannenstrasse 8
3018 Bern / CH
Inventor(s)01 / CHEVALIER, Yves
9 rue des Lavandes
F-69390 Vernaison / FR
02 / AGUSTI, Géraldine
15 rue des Charmettes
F-69100 Villeurbanne / FR
03 / NYFFENEGGER, Coralie
24-26 rue des Fauvettes
F-92260 Fontenay-aux-Roses / FR
04 / DOELKER, Eric
56 chemin de Conches
CH-1231 Conches / CH
05 / JORDAN, Olivier
15A chemin sous le Bois
CH-1197 Prangins / CH
06 / ANDERSEN, Gert
Engblommevej 47
DK-2400 Copenhague / DK
 [2013/03]
Representative(s)Pautex Schneider, Nicole Véronique, et al
Novagraaf International SA
Chemin de l'Echo 3
1213 Onex / CH
[2013/03]
Application number, filing date11707664.609.03.2011
[2016/42]
WO2011EP53536
Priority number, dateEP2010015603910.03.2010         Original published format: EP 10156039
[2013/03]
Filing languageEN
Procedural languageEN
PublicationType: A1 Application with search report
No.:WO2011110589
Date:15.09.2011
Language:EN
[2011/37]
Type: A1 Application with search report 
No.:EP2545085
Date:16.01.2013
Language:EN
The application published by WIPO in one of the EPO official languages on 15.09.2011 takes the place of the publication of the European patent application.
[2013/03]
Type: B1 Patent specification 
No.:EP2545085
Date:19.10.2016
Language:EN
[2016/42]
Search report(s)International search report - published on:EP15.09.2011
ClassificationIPC:C08F8/18, A61L24/00, C09D129/04, A61K49/04, A61L31/10
[2013/03]
CPC:
A61K49/0442 (EP,US); C08F8/18 (EP,KR,US); C08F116/06 (KR,US);
A61L24/00 (KR); A61L24/043 (EP,US); A61L24/06 (KR,US);
C08F16/06 (KR); C09D129/04 (KR); A61L2400/06 (EP,KR,US);
A61L2430/36 (EP,KR,US) (-)
C-Set:
A61L24/043, C08L27/10 (US,EP);
A61L24/043, C08L29/04 (US,EP);
C08F8/18, C08F16/06 (EP,US)
Designated contracting statesAL,   AT,   BE,   BG,   CH,   CY,   CZ,   DE,   DK,   EE,   ES,   FI,   FR,   GB,   GR,   HR,   HU,   IE,   IS,   IT,   LI,   LT,   LU,   LV,   MC,   MK,   MT,   NL,   NO,   PL,   PT,   RO,   RS,   SE,   SI,   SK,   SM,   TR [2013/03]
Extension statesBANot yet paid
MENot yet paid
TitleGerman:Radio-opaquen, nicht-abbaubaren, wasserunlösslichen, iodierten polyvinylakoholbenzyläther, Verfahren zur Herstellung, iniektierbaren embolisierenden Zusammensetzungen und deren Verwendung.[2016/31]
English:Radiopaque, non-biodegradable, water-insoluble iodinated benzyl ethers of poly(vinyl alcohol), preparation method thereof, injectable embolizing compositions containing thereof and use thereof[2016/31]
French:éthers de benzyle d'alcool polyvinylique iodinés, radio-opaques, non biodégradable, insoluble dans l'eau, leur méthode de préparation, compositions injectables embolisantes les contenant et leurs utilisation.[2016/31]
Former [2013/03]RÖNTGENDICHTE, NICHT BIOLOGISCH ABBAUBARE, WASSERUNLÖSLICHE IODIERTE BENZYLETHER AUS POLY(VINYLALKOHOL), HERSTELLUNGSVERFAHREN DAFÜR, INJIZIERBARE EMBOLISIERENDE ZUSAMMENSETZUNGEN DAMIT UND VERWENDUNG DAVON
Former [2013/03]RADIOPAQUE, NON- BIODEGRADABLE, WATER - INSOLUBLE IODINATED BENZYL ETHERS OF POLY (VINYL ALCOHOL), PREPARATION METHOD THEREOF, INJECTABLE EMBOLIZING COMPOSITIONS CONTAINING THEREOF AND USE THEREOF
Former [2013/03]ÉTHERS BENZYLIQUES DE POLY(ALCOOL VINYLIQUE) IODÉS, INSOLUBLES DANS L'EAU, NON BIODÉGRADABLES ET RADIO-OPAQUES, LEUR PROCÉDÉ DE PRÉPARATION, COMPOSITIONS D'EMBOLISATION INJECTABLES LES CONTENANT ET LEUR UTILISATION
Entry into regional phase22.08.2012National basic fee paid 
22.08.2012Designation fee(s) paid 
22.08.2012Examination fee paid 
Examination procedure22.08.2012Examination requested  [2013/03]
20.02.2013Amendment by applicant (claims and/or description)
21.10.2014Despatch of a communication from the examining division (Time limit: M04)
10.11.2014Reply to a communication from the examining division
09.12.2015Despatch of a communication from the examining division (Time limit: M04)
11.02.2016Reply to a communication from the examining division
19.07.2016Communication of intention to grant the patent
06.09.2016Fee for grant paid
06.09.2016Fee for publishing/printing paid
06.09.2016Receipt of the translation of the claim(s)
Divisional application(s)The date of the Examining Division's first communication in respect of the earliest application for which a communication has been issued is  21.10.2014
Opposition(s)20.07.2017No opposition filed within time limit [2017/39]
Fees paidRenewal fee
15.01.2013Renewal fee patent year 03
15.01.2014Renewal fee patent year 04
12.01.2015Renewal fee patent year 05
17.03.2016Renewal fee patent year 06
Opt-out from the exclusive  Tooltip
competence of the Unified
Patent Court		 See the Register of the Unified Patent Court for opt-out data
Responsibility for the accuracy, completeness or quality of the data displayed under the link provided lies entirely with the Unified Patent Court.
Lapses during opposition  TooltipHU09.03.2011
AL19.10.2016
AT19.10.2016
BE19.10.2016
CY19.10.2016
CZ19.10.2016
EE19.10.2016
FI19.10.2016
HR19.10.2016
LT19.10.2016
LV19.10.2016
MC19.10.2016
MK19.10.2016
RO19.10.2016
RS19.10.2016
SI19.10.2016
SK19.10.2016
SM19.10.2016
BG19.01.2017
NO19.01.2017
GR20.01.2017
IS19.02.2017
PT20.02.2017
LU09.03.2017
MT09.03.2017
[2020/33]
Former [2019/51]HU09.03.2011
AT19.10.2016
BE19.10.2016
CY19.10.2016
CZ19.10.2016
EE19.10.2016
FI19.10.2016
HR19.10.2016
LT19.10.2016
LV19.10.2016
MC19.10.2016
MK19.10.2016
RO19.10.2016
RS19.10.2016
SI19.10.2016
SK19.10.2016
SM19.10.2016
BG19.01.2017
NO19.01.2017
GR20.01.2017
IS19.02.2017
PT20.02.2017
LU09.03.2017
MT09.03.2017
Former [2019/46]HU09.03.2011
AT19.10.2016
BE19.10.2016
CY19.10.2016
CZ19.10.2016
EE19.10.2016
FI19.10.2016
HR19.10.2016
LT19.10.2016
LV19.10.2016
MC19.10.2016
RO19.10.2016
RS19.10.2016
SI19.10.2016
SK19.10.2016
SM19.10.2016
BG19.01.2017
NO19.01.2017
GR20.01.2017
IS19.02.2017
PT20.02.2017
LU09.03.2017
MT09.03.2017
Former [2019/31]HU09.03.2011
AT19.10.2016
BE19.10.2016
CZ19.10.2016
EE19.10.2016
FI19.10.2016
HR19.10.2016
LT19.10.2016
LV19.10.2016
MC19.10.2016
RO19.10.2016
RS19.10.2016
SI19.10.2016
SK19.10.2016
SM19.10.2016
BG19.01.2017
NO19.01.2017
GR20.01.2017
IS19.02.2017
PT20.02.2017
LU09.03.2017
MT09.03.2017
Former [2018/43]AT19.10.2016
BE19.10.2016
CZ19.10.2016
EE19.10.2016
FI19.10.2016
HR19.10.2016
LT19.10.2016
LV19.10.2016
MC19.10.2016
RO19.10.2016
RS19.10.2016
SI19.10.2016
SK19.10.2016
SM19.10.2016
BG19.01.2017
NO19.01.2017
GR20.01.2017
IS19.02.2017
PT20.02.2017
LU09.03.2017
MT09.03.2017
Former [2018/10]AT19.10.2016
BE19.10.2016
CZ19.10.2016
EE19.10.2016
FI19.10.2016
HR19.10.2016
LT19.10.2016
LV19.10.2016
MC19.10.2016
RO19.10.2016
RS19.10.2016
SI19.10.2016
SK19.10.2016
SM19.10.2016
BG19.01.2017
NO19.01.2017
GR20.01.2017
IS19.02.2017
PT20.02.2017
LU09.03.2017
Former [2017/52]AT19.10.2016
BE19.10.2016
CZ19.10.2016
EE19.10.2016
FI19.10.2016
HR19.10.2016
LT19.10.2016
LV19.10.2016
MC19.10.2016
RO19.10.2016
RS19.10.2016
SI19.10.2016
SK19.10.2016
SM19.10.2016
BG19.01.2017
NO19.01.2017
GR20.01.2017
IS19.02.2017
PT20.02.2017
Former [2017/38]AT19.10.2016
BE19.10.2016
CZ19.10.2016
EE19.10.2016
FI19.10.2016
HR19.10.2016
LT19.10.2016
LV19.10.2016
RO19.10.2016
RS19.10.2016
SK19.10.2016
SM19.10.2016
BG19.01.2017
NO19.01.2017
GR20.01.2017
IS19.02.2017
PT20.02.2017
Former [2017/36]AT19.10.2016
BE19.10.2016
CZ19.10.2016
EE19.10.2016
FI19.10.2016
HR19.10.2016
LT19.10.2016
LV19.10.2016
RO19.10.2016
RS19.10.2016
SK19.10.2016
NO19.01.2017
GR20.01.2017
IS19.02.2017
PT20.02.2017
Former [2017/35]AT19.10.2016
BE19.10.2016
CZ19.10.2016
EE19.10.2016
FI19.10.2016
HR19.10.2016
LT19.10.2016
LV19.10.2016
RO19.10.2016
RS19.10.2016
NO19.01.2017
GR20.01.2017
IS19.02.2017
PT20.02.2017
Former [2017/34]AT19.10.2016
BE19.10.2016
CZ19.10.2016
FI19.10.2016
HR19.10.2016
LT19.10.2016
LV19.10.2016
RS19.10.2016
NO19.01.2017
GR20.01.2017
IS19.02.2017
PT20.02.2017
Former [2017/26]AT19.10.2016
BE19.10.2016
FI19.10.2016
HR19.10.2016
LT19.10.2016
LV19.10.2016
RS19.10.2016
NO19.01.2017
GR20.01.2017
IS19.02.2017
PT20.02.2017
Former [2017/12]LV19.10.2016
Cited inInternational search[I]CN101513542  ;
 [Y]WO9912577  (NYCOMED IMAGING AS [NO], et al) [Y] 20* claims 1-5 *;
 [Y]WO0122948  (ROSENBLATT SOLOMON [US]) [Y] 25 * abstract *;
 [IY]  - MAWAD DAMIA ET AL, "Synthesis and characterization of radiopaque iodine-containing degradable PVA hydrogels", BIOMACROMOLECULES, ACS, WASHINGTON, DC, US, vol. 9, no. 1, ISSN 1525-7797, (20071130), pages 263 - 268, (20071130), XP002544191 [I] 1-27 * abstract * * page 263 - page 264 * [Y] 20,25-27

DOI:   http://dx.doi.org/10.1021/bm700754m
 [Y]  - KIM ET AL, "Biomedical applications of superparamagnetic iron oxide nanoparticles encapsulated within chitosan", JOURNAL OF ALLOYS AND COMPOUNDS, ELSEVIER SEQUOIA, LAUSANNE, CH, (20070329), vol. 434-435, doi:DOI:10.1016/J.JALLCOM.2006.08.311, ISSN 0925-8388, pages 633 - 636, XP022008743 [Y] 20 * abstract *

DOI:   http://dx.doi.org/10.1016/j.jallcom.2006.08.311
 [Y]  - MAWAD D ET AL, "Elaboration of radiopaque iodinated nanoparticles for in situ control of local drug delivery", BIOMATERIALS, ELSEVIER SCIENCE PUBLISHERS BV., BARKING, GB, vol. 30, no. 29, doi:DOI:10.1016/J.BIOMATERIALS.2009.06.027, ISSN 0142-9612, (20091001), pages 5667 - 5674, (20090704), XP026469992 [Y] 26,27 * abstract * * page 5667 - page 5668 *

DOI:   http://dx.doi.org/10.1016/j.biomaterials.2009.06.027
 [I]  - DATABASE WPI, 0, Derwent World Patents Index, vol. 2009, no. 66, Database accession no. 2009-N34393, XP002630295 & CN101513542 A 20090826 (SHANDONG DAZHENG MEDICAL APPLIANCE CO LT) [I] 1-27 * abstract *
by applicantUS5580568
 US5695480
 US5851508
 WO2006125452
    - O. JORDAN ET AL., "Novel organic vehicles for the embolization of vascular malformations and intracranial aneurysms", 19TH EUROPEAN CONFERENCE ON BIOMATERIALS, 2005, SORRENTO
    - O. JORDAN ET AL., AMERICAN SOCIETY OF NEURORADIOLOGY 42ND ANNUAL MEETING, SEATTLE, JUNE 5-11, 2004
    - O. DUDECK, O. JORDAN ET AL., "Liquid Embolization of Experimental Wide-Necked Aneurysms with Polyvinyl Alcohol Polymer: A New, Nonadhesive, Iodine-Containing Liquid Embolic Agent", AM. J. NEURORADIOL., (2006), vol. 27, pages 1900 - 1906
    - O. DUDECK; O. JORDAN ET AL., "Organic solvents as vehicles for precipitating liquid embohcs", AM. J. NEURORADIOL., (200610), vol. 27, pages 1849 - 55
    - 0. DUDECK; O. JORDAN ET AL., "Embolization of Experimental Wide-Necked Aneurysm with Iodine-Containing Polyvinyl Alcohol Solubilized in a Low-Angiotoxicity Solvent", J. NEUROSURG, (200602), vol. 104, pages 290 - 297
    - MATTHIEU CHASTELLAIN ET AL., "Superparamagnetic Silica-Iron Oxide Nanocomposites for Application in Hyperthermia", ADVANCED ENGINEERING MATERIALS, (2004), vol. 6, doi:doi:10.1002/adem.200300574, pages 235 - 241, XP008125449

DOI:   http://dx.doi.org/10.1002/adem.200300574
    - D. MAWAD; H. MOUAZIZ; A. PENCIU; H. MEHIER; B. FENET; H. FESSI; Y. CHEVALIER, "Elaboration of radiopaque iodinated nanoparticles for in situ control of local drug delivery", BIOMATERIALS, (2009), vol. 30, doi:doi:10.1016/j.biomaterials.2009.06.027, pages 5667 - 5674, XP026469992

DOI:   http://dx.doi.org/10.1016/j.biomaterials.2009.06.027
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