EP2512495 - PROCESS FOR OBTAINING A STANDARDISED EXTRACT OF QUERCETIN AN 3-O-METHYLQUERCETIN FROM FLOWERS OF MACELA (ACHYROCLINE SATUREIOIDES), AND COSMETIC AND PHARMACEUTICAL COMPOSITIONS COMPRISING SAID EXTRACT [Right-click to bookmark this link] | |||
Former [2012/43] | PROCESS FOR OBTAINING A STANDARDISED EXTRACT OF QUERCETIN AND 3-0-METHYLQUERCETIN FROM FLOWERS OF MACELA (ACHYROCLINE SATUREIOIDES), AND COSMETIC AND PHARMACEUTICAL COMPOSITIONS COMPRISING SAID EXTRACT | ||
[2015/15] | Status | No opposition filed within time limit Status updated on 15.07.2016 Database last updated on 22.08.2024 | Most recent event Tooltip | 19.10.2018 | Lapse of the patent in a contracting state New state(s): AL | published on 21.11.2018 [2018/47] | Applicant(s) | For all designated states Natura Cosméticos S.A. Rodovia Regis Bittencourt, Km 293 06882-700 Itape Cerica da Serra SP / BR | [2015/37] |
Former [2012/43] | For all designated states Natura Cosméticos S.A. Rodovia Regis Bittencourt, Km 293 06882-700 Itape Cerica da Serra SP / BR | Inventor(s) | 01 /
MOURA SA ROCHA, Vanessa de Alameda Jau 1874 apto. 9-B Jardim Paulista 01420-002 - Sao Paulo - SP / BR | 02 /
DELARCINA JUNIOR, Sergio Rua Dias Vieira 326 Apto 404 Vila Sonia 05632-090 - Sao Paulo - SP / BR | 03 /
FIGUEREDO BEDA, Débora Av. Diogo de Azevedo 22 Apto 131 A 05376-140 - Sao Paulo - SP / BR | 04 /
LORENCINI, Marcio Av. Albino Jose Barbosa de Oliveira 2300 Casa 2 Bairro Jardim Atlfe 13084-551 - Campinas - SP / BR | 05 /
COSTA BEBER, Tiago Rua Pedro Taques 117 Apto 123 Consolacao 01415-010 - Sao Paulo - SP / BR | 06 /
PASSERO, Alan Rua Paulina Ortega 355 - Jd Monte Alegre 06755-240 - Taboao da Serra - SP / BR | [2012/43] | Representative(s) | Pearson, Samuel John, et al Abel & Imray 20 Red Lion Street London WC1R 4PQ / GB | [2014/04] |
Former [2012/43] | Senior, Janet, et al Abel & Imray 20 Red Lion Street London WC1R 4PQ / GB | Application number, filing date | 11710252.5 | 06.01.2011 | [2015/37] | WO2011IB00015 | Priority number, date | FR20090059012 | 15.12.2009 Original published format: FR 0959012 | [2012/43] | Filing language | EN | Procedural language | EN | Publication | Type: | A1 Application with search report | No.: | WO2011073961 | Date: | 23.06.2011 | Language: | EN | [2011/25] | Type: | A1 Application with search report | No.: | EP2512495 | Date: | 24.10.2012 | Language: | EN | The application published by WIPO in one of the EPO official languages on 23.06.2011 takes the place of the publication of the European patent application. | [2012/43] | Type: | B1 Patent specification | No.: | EP2512495 | Date: | 09.09.2015 | Language: | EN | [2015/37] | Search report(s) | International search report - published on: | EP | 23.06.2011 | Classification | IPC: | A61K36/28, A61P17/10, A61P29/00 | [2012/43] | CPC: |
A61K36/28 (EP,US);
A61P17/00 (EP);
A61P17/10 (EP);
A61P19/00 (EP);
A61P29/00 (EP);
A61P31/00 (EP);
A61K2236/331 (EP,US)
(-)
| Designated contracting states | AL, AT, BE, BG, CH, CY, CZ, DE, DK, EE, ES, FI, FR, GB, GR, HR, HU, IE, IS, IT, LI, LT, LU, LV, MC, MK, MT, NL, NO, PL, PT, RO, RS, SE, SI, SK, SM, TR [2012/43] | Extension states | BA | Not yet paid | ME | Not yet paid | Title | German: | VERFAHREN ZUR HERSTELLUNG EINES STANDARDISIERSTES QUERCETIN UND 3-O-METHYLQUERCETIN EXTRAKTS AUS MACELA (ACHYROCLINE SATUREIOIDES) BLÜTEN, UND KOSMETISCHE UND PHARMAZEUTISCHE ZUSAMMENZETZUNGEN, DIE DEN EXTRAKT ENTHALTEN | [2015/15] | English: | PROCESS FOR OBTAINING A STANDARDISED EXTRACT OF QUERCETIN AN 3-O-METHYLQUERCETIN FROM FLOWERS OF MACELA (ACHYROCLINE SATUREIOIDES), AND COSMETIC AND PHARMACEUTICAL COMPOSITIONS COMPRISING SAID EXTRACT | [2015/15] | French: | PROCEDE POUR OBTENIR UN EXTRAIT STANDARDISE DE QUERCETINE ET DE 3-O-METHYLQUERCETINE A PARTIR D'INFLORESCENCES DE MACELA-DO-CAMPO, ET COMPOSITION COSMETIQUE, PHARMACEUTIQUE ET VETERINAIRE LE CONTENANT | [2015/15] |
Former [2012/43] | VERFAHREN ZUR GEWINNUNG EINES STANDARDISIERTEN EXTRAKTS AUS QUERCETIN UND 3-0-METHYLQUERCETIN AUS DER BLUMENART MACELA (ACHYROCLINE SATUREIOIDES) SOWIE KOSMETISCHE UND PHARMAZEUTISCHE ZUSAMMENSETZUNGEN MIT DIESEM EXTRAKT | ||
Former [2012/43] | PROCESS FOR OBTAINING A STANDARDISED EXTRACT OF QUERCETIN AND 3-0-METHYLQUERCETIN FROM FLOWERS OF MACELA (ACHYROCLINE SATUREIOIDES), AND COSMETIC AND PHARMACEUTICAL COMPOSITIONS COMPRISING SAID EXTRACT | ||
Former [2012/43] | PROCÉDÉ D'OBTENTION D'UN EXTRAIT STANDARDISÉ DE QUERCÉTINE ET DE 3-O-MÉTHYLQUERCÉTINE À PARTIR DE FLEURS DE MACELA, COMPOSITIONS COSMÉTIQUE, PHARMACEUTIQUE ET VÉTÉRINAIRE CONTENANT LEDIT L'EXTRAIT | Entry into regional phase | 21.06.2012 | National basic fee paid | 21.06.2012 | Designation fee(s) paid | 21.06.2012 | Examination fee paid | Examination procedure | 14.10.2011 | Request for preliminary examination filed International Preliminary Examining Authority: EP | 21.06.2012 | Examination requested [2012/43] | 21.05.2013 | Amendment by applicant (claims and/or description) | 26.02.2014 | Despatch of a communication from the examining division (Time limit: M06) | 08.10.2014 | Despatch of communication that the application is deemed to be withdrawn, reason: reply to the communication from the examining division not received in time | 30.10.2014 | Reply to a communication from the examining division | 27.03.2015 | Communication of intention to grant the patent | 30.07.2015 | Fee for grant paid | 30.07.2015 | Fee for publishing/printing paid | 30.07.2015 | Receipt of the translation of the claim(s) | Divisional application(s) | The date of the Examining Division's first communication in respect of the earliest application for which a communication has been issued is 26.02.2014 | Opposition(s) | 10.06.2016 | No opposition filed within time limit [2016/33] | Request for further processing for: | The application is deemed to be withdrawn due to failure to reply to the examination report | 30.10.2014 | Request for further processing filed | 30.10.2014 | Full payment received (date of receipt of payment) Request granted | 13.11.2014 | Decision despatched | 21.05.2013 | Request for further processing filed | 21.05.2013 | Full payment received (date of receipt of payment) Request granted | 05.06.2013 | Decision despatched | Fees paid | Renewal fee | 10.01.2013 | Renewal fee patent year 03 | 27.01.2014 | Renewal fee patent year 04 | 30.01.2015 | Renewal fee patent year 05 |
Opt-out from the exclusive Tooltip competence of the Unified Patent Court | See the Register of the Unified Patent Court for opt-out data | ||
Responsibility for the accuracy, completeness or quality of the data displayed under the link provided lies entirely with the Unified Patent Court. | Lapses during opposition Tooltip | HU | 06.01.2011 | AL | 09.09.2015 | AT | 09.09.2015 | BE | 09.09.2015 | BG | 09.09.2015 | CY | 09.09.2015 | CZ | 09.09.2015 | DK | 09.09.2015 | EE | 09.09.2015 | FI | 09.09.2015 | HR | 09.09.2015 | LT | 09.09.2015 | LV | 09.09.2015 | MC | 09.09.2015 | MK | 09.09.2015 | NL | 09.09.2015 | PL | 09.09.2015 | RO | 09.09.2015 | RS | 09.09.2015 | SE | 09.09.2015 | SI | 09.09.2015 | SK | 09.09.2015 | SM | 09.09.2015 | TR | 09.09.2015 | NO | 09.12.2015 | GR | 10.12.2015 | IE | 06.01.2016 | LU | 06.01.2016 | IS | 09.01.2016 | PT | 11.01.2016 | CH | 31.01.2016 | LI | 31.01.2016 | MT | 31.01.2016 | [2018/47] |
Former [2018/38] | HU | 06.01.2011 | |
AT | 09.09.2015 | ||
BE | 09.09.2015 | ||
BG | 09.09.2015 | ||
CY | 09.09.2015 | ||
CZ | 09.09.2015 | ||
DK | 09.09.2015 | ||
EE | 09.09.2015 | ||
FI | 09.09.2015 | ||
HR | 09.09.2015 | ||
LT | 09.09.2015 | ||
LV | 09.09.2015 | ||
MC | 09.09.2015 | ||
MK | 09.09.2015 | ||
NL | 09.09.2015 | ||
PL | 09.09.2015 | ||
RO | 09.09.2015 | ||
RS | 09.09.2015 | ||
SE | 09.09.2015 | ||
SI | 09.09.2015 | ||
SK | 09.09.2015 | ||
SM | 09.09.2015 | ||
TR | 09.09.2015 | ||
NO | 09.12.2015 | ||
GR | 10.12.2015 | ||
IE | 06.01.2016 | ||
LU | 06.01.2016 | ||
IS | 09.01.2016 | ||
PT | 11.01.2016 | ||
CH | 31.01.2016 | ||
LI | 31.01.2016 | ||
MT | 31.01.2016 | ||
Former [2018/31] | HU | 06.01.2011 | |
AT | 09.09.2015 | ||
BE | 09.09.2015 | ||
CY | 09.09.2015 | ||
CZ | 09.09.2015 | ||
DK | 09.09.2015 | ||
EE | 09.09.2015 | ||
FI | 09.09.2015 | ||
HR | 09.09.2015 | ||
LT | 09.09.2015 | ||
LV | 09.09.2015 | ||
MC | 09.09.2015 | ||
MK | 09.09.2015 | ||
NL | 09.09.2015 | ||
PL | 09.09.2015 | ||
RO | 09.09.2015 | ||
RS | 09.09.2015 | ||
SE | 09.09.2015 | ||
SI | 09.09.2015 | ||
SK | 09.09.2015 | ||
SM | 09.09.2015 | ||
TR | 09.09.2015 | ||
NO | 09.12.2015 | ||
GR | 10.12.2015 | ||
IE | 06.01.2016 | ||
LU | 06.01.2016 | ||
IS | 09.01.2016 | ||
PT | 11.01.2016 | ||
CH | 31.01.2016 | ||
LI | 31.01.2016 | ||
MT | 31.01.2016 | ||
Former [2018/29] | HU | 06.01.2011 | |
AT | 09.09.2015 | ||
BE | 09.09.2015 | ||
CY | 09.09.2015 | ||
CZ | 09.09.2015 | ||
DK | 09.09.2015 | ||
EE | 09.09.2015 | ||
FI | 09.09.2015 | ||
HR | 09.09.2015 | ||
LT | 09.09.2015 | ||
LV | 09.09.2015 | ||
MC | 09.09.2015 | ||
MK | 09.09.2015 | ||
MT | 09.09.2015 | ||
NL | 09.09.2015 | ||
PL | 09.09.2015 | ||
RO | 09.09.2015 | ||
RS | 09.09.2015 | ||
SE | 09.09.2015 | ||
SI | 09.09.2015 | ||
SK | 09.09.2015 | ||
SM | 09.09.2015 | ||
TR | 09.09.2015 | ||
NO | 09.12.2015 | ||
GR | 10.12.2015 | ||
IE | 06.01.2016 | ||
LU | 06.01.2016 | ||
IS | 09.01.2016 | ||
PT | 11.01.2016 | ||
CH | 31.01.2016 | ||
LI | 31.01.2016 | ||
Former [2018/28] | HU | 06.01.2011 | |
AT | 09.09.2015 | ||
BE | 09.09.2015 | ||
CY | 09.09.2015 | ||
CZ | 09.09.2015 | ||
DK | 09.09.2015 | ||
EE | 09.09.2015 | ||
FI | 09.09.2015 | ||
HR | 09.09.2015 | ||
LT | 09.09.2015 | ||
LV | 09.09.2015 | ||
MC | 09.09.2015 | ||
MK | 09.09.2015 | ||
MT | 09.09.2015 | ||
NL | 09.09.2015 | ||
PL | 09.09.2015 | ||
RO | 09.09.2015 | ||
RS | 09.09.2015 | ||
SE | 09.09.2015 | ||
SI | 09.09.2015 | ||
SK | 09.09.2015 | ||
SM | 09.09.2015 | ||
NO | 09.12.2015 | ||
GR | 10.12.2015 | ||
IE | 06.01.2016 | ||
LU | 06.01.2016 | ||
IS | 09.01.2016 | ||
PT | 11.01.2016 | ||
CH | 31.01.2016 | ||
LI | 31.01.2016 | ||
Former [2017/47] | AT | 09.09.2015 | |
BE | 09.09.2015 | ||
CZ | 09.09.2015 | ||
DK | 09.09.2015 | ||
EE | 09.09.2015 | ||
FI | 09.09.2015 | ||
HR | 09.09.2015 | ||
LT | 09.09.2015 | ||
LV | 09.09.2015 | ||
MC | 09.09.2015 | ||
MT | 09.09.2015 | ||
NL | 09.09.2015 | ||
PL | 09.09.2015 | ||
RO | 09.09.2015 | ||
RS | 09.09.2015 | ||
SE | 09.09.2015 | ||
SI | 09.09.2015 | ||
SK | 09.09.2015 | ||
NO | 09.12.2015 | ||
GR | 10.12.2015 | ||
IE | 06.01.2016 | ||
LU | 06.01.2016 | ||
IS | 09.01.2016 | ||
PT | 11.01.2016 | ||
CH | 31.01.2016 | ||
LI | 31.01.2016 | ||
Former [2017/07] | AT | 09.09.2015 | |
BE | 09.09.2015 | ||
CZ | 09.09.2015 | ||
DK | 09.09.2015 | ||
EE | 09.09.2015 | ||
FI | 09.09.2015 | ||
HR | 09.09.2015 | ||
LT | 09.09.2015 | ||
LV | 09.09.2015 | ||
MC | 09.09.2015 | ||
NL | 09.09.2015 | ||
PL | 09.09.2015 | ||
RO | 09.09.2015 | ||
RS | 09.09.2015 | ||
SE | 09.09.2015 | ||
SI | 09.09.2015 | ||
SK | 09.09.2015 | ||
NO | 09.12.2015 | ||
GR | 10.12.2015 | ||
IE | 06.01.2016 | ||
LU | 06.01.2016 | ||
IS | 09.01.2016 | ||
PT | 11.01.2016 | ||
CH | 31.01.2016 | ||
LI | 31.01.2016 | ||
Former [2017/03] | AT | 09.09.2015 | |
BE | 09.09.2015 | ||
CZ | 09.09.2015 | ||
DK | 09.09.2015 | ||
EE | 09.09.2015 | ||
FI | 09.09.2015 | ||
HR | 09.09.2015 | ||
LT | 09.09.2015 | ||
LV | 09.09.2015 | ||
MC | 09.09.2015 | ||
NL | 09.09.2015 | ||
PL | 09.09.2015 | ||
RO | 09.09.2015 | ||
RS | 09.09.2015 | ||
SE | 09.09.2015 | ||
SI | 09.09.2015 | ||
SK | 09.09.2015 | ||
NO | 09.12.2015 | ||
GR | 10.12.2015 | ||
LU | 06.01.2016 | ||
IS | 09.01.2016 | ||
PT | 11.01.2016 | ||
CH | 31.01.2016 | ||
LI | 31.01.2016 | ||
Former [2016/46] | AT | 09.09.2015 | |
CZ | 09.09.2015 | ||
DK | 09.09.2015 | ||
EE | 09.09.2015 | ||
FI | 09.09.2015 | ||
HR | 09.09.2015 | ||
LT | 09.09.2015 | ||
LV | 09.09.2015 | ||
MC | 09.09.2015 | ||
NL | 09.09.2015 | ||
PL | 09.09.2015 | ||
RO | 09.09.2015 | ||
RS | 09.09.2015 | ||
SE | 09.09.2015 | ||
SI | 09.09.2015 | ||
SK | 09.09.2015 | ||
NO | 09.12.2015 | ||
GR | 10.12.2015 | ||
LU | 06.01.2016 | ||
IS | 09.01.2016 | ||
PT | 11.01.2016 | ||
BE | 31.01.2016 | ||
CH | 31.01.2016 | ||
LI | 31.01.2016 | ||
Former [2016/42] | AT | 09.09.2015 | |
CZ | 09.09.2015 | ||
DK | 09.09.2015 | ||
EE | 09.09.2015 | ||
FI | 09.09.2015 | ||
HR | 09.09.2015 | ||
LT | 09.09.2015 | ||
LV | 09.09.2015 | ||
MC | 09.09.2015 | ||
NL | 09.09.2015 | ||
PL | 09.09.2015 | ||
RO | 09.09.2015 | ||
RS | 09.09.2015 | ||
SE | 09.09.2015 | ||
SI | 09.09.2015 | ||
SK | 09.09.2015 | ||
NO | 09.12.2015 | ||
GR | 10.12.2015 | ||
LU | 06.01.2016 | ||
IS | 09.01.2016 | ||
PT | 11.01.2016 | ||
BE | 31.01.2016 | ||
Former [2016/39] | AT | 09.09.2015 | |
CZ | 09.09.2015 | ||
DK | 09.09.2015 | ||
EE | 09.09.2015 | ||
FI | 09.09.2015 | ||
HR | 09.09.2015 | ||
LT | 09.09.2015 | ||
LV | 09.09.2015 | ||
NL | 09.09.2015 | ||
PL | 09.09.2015 | ||
RO | 09.09.2015 | ||
RS | 09.09.2015 | ||
SE | 09.09.2015 | ||
SI | 09.09.2015 | ||
SK | 09.09.2015 | ||
NO | 09.12.2015 | ||
GR | 10.12.2015 | ||
LU | 06.01.2016 | ||
IS | 09.01.2016 | ||
PT | 11.01.2016 | ||
BE | 31.01.2016 | ||
Former [2016/36] | AT | 09.09.2015 | |
CZ | 09.09.2015 | ||
EE | 09.09.2015 | ||
FI | 09.09.2015 | ||
HR | 09.09.2015 | ||
LT | 09.09.2015 | ||
LV | 09.09.2015 | ||
NL | 09.09.2015 | ||
PL | 09.09.2015 | ||
RO | 09.09.2015 | ||
RS | 09.09.2015 | ||
SE | 09.09.2015 | ||
SI | 09.09.2015 | ||
SK | 09.09.2015 | ||
NO | 09.12.2015 | ||
GR | 10.12.2015 | ||
IS | 09.01.2016 | ||
PT | 11.01.2016 | ||
BE | 31.01.2016 | ||
Former [2016/24] | AT | 09.09.2015 | |
CZ | 09.09.2015 | ||
EE | 09.09.2015 | ||
FI | 09.09.2015 | ||
HR | 09.09.2015 | ||
LT | 09.09.2015 | ||
LV | 09.09.2015 | ||
NL | 09.09.2015 | ||
PL | 09.09.2015 | ||
RO | 09.09.2015 | ||
RS | 09.09.2015 | ||
SE | 09.09.2015 | ||
SK | 09.09.2015 | ||
NO | 09.12.2015 | ||
GR | 10.12.2015 | ||
IS | 09.01.2016 | ||
PT | 11.01.2016 | ||
BE | 31.01.2016 | ||
Former [2016/23] | CZ | 09.09.2015 | |
EE | 09.09.2015 | ||
FI | 09.09.2015 | ||
HR | 09.09.2015 | ||
LT | 09.09.2015 | ||
LV | 09.09.2015 | ||
NL | 09.09.2015 | ||
RO | 09.09.2015 | ||
RS | 09.09.2015 | ||
SE | 09.09.2015 | ||
SK | 09.09.2015 | ||
NO | 09.12.2015 | ||
GR | 10.12.2015 | ||
IS | 09.01.2016 | ||
Former [2016/22] | CZ | 09.09.2015 | |
EE | 09.09.2015 | ||
FI | 09.09.2015 | ||
HR | 09.09.2015 | ||
LT | 09.09.2015 | ||
LV | 09.09.2015 | ||
NL | 09.09.2015 | ||
RS | 09.09.2015 | ||
SE | 09.09.2015 | ||
NO | 09.12.2015 | ||
GR | 10.12.2015 | ||
IS | 09.01.2016 | ||
Former [2016/14] | FI | 09.09.2015 | |
HR | 09.09.2015 | ||
LT | 09.09.2015 | ||
LV | 09.09.2015 | ||
NL | 09.09.2015 | ||
RS | 09.09.2015 | ||
SE | 09.09.2015 | ||
NO | 09.12.2015 | ||
GR | 10.12.2015 | ||
Former [2016/11] | FI | 09.09.2015 | |
HR | 09.09.2015 | ||
LT | 09.09.2015 | ||
LV | 09.09.2015 | ||
RS | 09.09.2015 | ||
SE | 09.09.2015 | ||
NO | 09.12.2015 | ||
GR | 10.12.2015 | ||
Former [2016/09] | FI | 09.09.2015 | |
LT | 09.09.2015 | ||
LV | 09.09.2015 | ||
NO | 09.12.2015 | ||
GR | 10.12.2015 | ||
Former [2016/08] | LT | 09.09.2015 | |
NO | 09.12.2015 | ||
Former [2016/07] | LT | 09.09.2015 | Cited in | International search | [Y]JPS5944313 ; | [YD]BR0103468 (UNIV FED DO RIO GRANDE DO SUL [BR]) [YD] 6-10 * see claims 1-10, page 4 and table 3 *; | [XY]EP1475097 (DAJAS MENDEZ JOSE FEDERICO [UY], et al) [X] 6-10 * see claims1-16 *[Y] 1-10; | [Y]US2008070875 (MAJEWSKI GEORGE P [US], et al) [Y] 9,10 * see claim 1, paragraphs [0013], [0025] *; | [XY] - DIAZ CLAUDIA ET AL, "Variations in the flavonoid profile and free quercetin content in different extracts of Achyrocline satureoides", ACTA FARMACEUTICA BONAERENSE, COLEGIO DE FARMACEUTICOS DE LA PROVINCIA DE BUENOS AIRES, AR, (20061001), vol. 25, no. 4, ISSN 0326-2383, pages 574 - 577, XP009135059 [X] 6-8 * the whole document * [Y] 1-10 | [Y] - DATABASE WPI, 0, Derwent World Patents Index, vol. 1984, no. 16, Database accession no. 1984-098314, XP002590550 & JPS5944313 A 19840312 (YAKULT HONSHA KK) [Y] 9,10 * abstract * | [Y] - SIMOES C M O ET AL, "ANTIINFLAMMATORY ACTION OF ACHYROCLINE SATUREIOIDES EXTRACTS APPLIED TOPICALLY", FITOTERAPIA, IDB HOLDING, MILAN, IT, (19880101), vol. 59, no. 5, ISSN 0367-326X, pages 419 - 421, XP009033958 [Y] 6-10 * see abstract, page 419, table 1 * | [YD] - MORQUIO A. ET AL., "Photoprotection by topical application of Achyrocline satureioides ("Marcela")", PHYTOTHER. RES., (2005), vol. 19, pages 486 - 490, XP002590551 [YD] 9,10 * seec abstract and page 487 * DOI: http://dx.doi.org/10.1002/PTR.1665 | by applicant | JPS5944313B | JPH10226619 | BR0103468 | US2004170581 | US2004220119 | US7192611 | US2008070875 | - CARNEY, J.R. ET AL., "Achyrofuran, a new antihyperglycemic dibenzofuran from the South American medicinal plant Achyrocline satureioides", J. NAT. PROD., (2002), vol. 65, no. 2, doi:doi:10.1021/NP010374L, pages 203 - 205, XP002591817 DOI: http://dx.doi.org/10.1021/NP010374L | - CHAN AL, HUANG HL, CHIEN HC, CHEN CM, LIN CN, KO WC, "Inhibitory effects of quercetin derivatives on phosphodiesterase isozymes and high-affinity [(3) H]-rolipram binding in guinea pig tissues", INVEST NEW DRUGS., (200810), vol. 26, no. 5, pages 417 - 24, XP019602926 | - D'AVILA, M.C., Dissertação, FACUL- DADE LIVRE DE MEDICINA E FARMACIA DE PORTO ALEGRE, (1910), page 155 | - HNATYSZYN, O. ET AL., "Flavonoids from Achyrocline satureioides with relaxant effects on the smooth muscle of Guinea pig corpus cavernosum", PHYTOMEDICINE, (2004), vol. 11, no. 4, doi:doi:10.1078/0944711041495182, pages 366 - 369, XP004957010 DOI: http://dx.doi.org/10.1078/0944711041495182 | - IKUTA, A.R.Y., Dissertation, FEDERAL UNIVERSITY OF RIO GRANDE DO SUL, (1993), page 205 | - JIANG, J.-S. ET AL., "Potent suppressive effects of 3-O-methylquercetin 5,7,3',4'-O-tetraacetate on ovalbumin-induced airway hyperresponsiveness", PLANTA MEDICA, (2007), vol. 73, no. 11, pages 156 - 1162 | - KADARIAN, C. ET AL., "Hepatoprotective activity of Achyrocline satureioides (Lam) D. C.", PHARMACOL. RES., (2002), vol. 45, no. 1, pages 57 - 61 | - KO WC, WANG HL, LEI CB, SHIH CH, CHUNG MI, LIN CN, "Mechanisms of relaxant action of 3-O-methylquercetin in isolated guinea pig trachea", PLANTA MED., (200201), vol. 68, no. 1, pages 30 - 5 | - LEMOS, G.C.S., "Bacterial activity of macela (Achyrocline satureioides) against strains of Staphylococcus aureus isolated from subclinical bovine mastitis", REV. BRAS. PI. MED., (2000), vol. 3, no. 1, pages 67 - 72 | - LINES, T.C., "ONO, M. FRS 1000, an extract of red onion peel, strongly inhi bits phosphodiesterase 5a (pde 5a)", PHYTOMEDICINE, (2006), vol. 13, no. 4, pages 236 - 239 | - MARQUES, F.C., BARROS, I.B.I., "Crescimento inicial de marcela (Achyrocline satureioides) em ambiente protegido (Initial growth of marcela (Achyrocline satureioides) in a protected environment)", RURAL SCIENCE, (2001), vol. 31, no. 1, pages 517 - 518 | - MARQUES, F.C., BARROS, I.B.I., "Qualidade de sementes de marcela (Achyrocline satureioides) provenientes de duas populações do Rio Grande do Sul (Quality of seeds of marcela (Achyrocline satureioides) from two populations of Rio Grande do Sul)", RURAL SCIENCE, (2000), vol. 30, no. 2, pages 241 - 247 | - "Análise da qualidade de sementes de marcela", MARQUES, F.C., Analysis of the quality of seeds of marcela, Achyrocline, RIO GRANDE DO SUL | - Dissertation (Master's Degree in Plant Science) - Master's Course in Plant Science, FEDERAL UNIVERSITY OF RIO GRANDE DO SUL, (1995), page 143 | - "Flora medicinal dos sitiantes da Reserva Particular do Patrimônio Natural das Pedras, Mangaratiba, Rio de Janeiro, Brasil:taxonomia e aspectos etnobotânicos", MEDEIROS, M. F.T., REGINA HELENA P. ET AL., Medicinal flora of the farms of the Private Reserve of Natural Heritage, Rio das Pedras, Mangaratiba, Rio de Janeiro, Brazil: Taxonomy and ethnobotanic aspects., PUBL. A-VUL. MUS. NAC., (200503), pages 3 - 24 | - OLIVEIRA ET AL., "Achyrocline satureioides, Asteraceae, comparative evaluation of the plant ingredient and preliminary studies of the optimization of extraction", PHARMACY NOTEBOOK, (2001), vol. 17, no. 1, pages 33 - 38 | - "Estaquia de marcela Achyrocline satureioides (Lam.) D.C. sob diferentes periodos de enraizamento e doses de acido indolbutirico (Staking of marcela Achyrocline satureioides (Lam.) D.C. under different", PARDO, V.A, Dissertation (Master's Degree in Plant Science) - Master's Course in Plant Science, FEDERAL UNIVERSITY OF RIO GRANDE DO SUL, (1995), page 78 | - RITTER, "Plantas usadas como medicinais no municipio de Ipê. (Plants used as medicines in the municipality of Ipê)", RS. REV. BRAS. FARMACOGN., (2002), vol. 12, no. 2, pages 51 - 62 | - SIMOES, C.M.O., "Antiinflammatory action of Achyrocline satureioides extracts applied topically", FITOTERAPIA, (1988), vol. 59, no. 5, pages 419 - 421, XP009033958 |