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Extract from the Register of European Patents

EP About this file: EP2556143

EP2556143 - METHOD FOR ISOLATING AND PURIFYING NUCLEIC ACIDS [Right-click to bookmark this link]
StatusOpposition rejected
Status updated on  02.08.2019
Database last updated on 19.07.2024
FormerThe patent has been granted
Status updated on  04.11.2016
Most recent event   Tooltip10.07.2020Lapse of the patent in a contracting state
New state(s): AL
published on 12.08.2020  [2020/33]
Applicant(s)For all designated states
Qiagen GmbH
Qiagen Str. 1
40724 Hilden / DE
[2016/49]
Former [2013/07]For all designated states
Qiagen GmbH
Qiagen Str. 1
40724 Hilden / DE
Inventor(s)01 / FABIS, Roland
Qiagen GmbH
Qiagen Str. 1
40724 Hilden / DE
02 / MÜLLER, Markus
Qiagen GmbH
Qiagen Str. 1
40724 Hilden / DE
03 / HUCKLENBROICH, Jörg
Qiagen GmbH
Qiagen Str. 1
40724 Hilden / DE
04 / SCHERER, Mario
Qiagen GmbH
Qiagen Str.1
40724 Hilden / DE
 [2013/07]
Representative(s)f & e patent
Braunsberger Feld 29
51429 Bergisch Gladbach / DE
[N/P]
Former [2016/49]f & e patent
Fleischer, Engels & Partner mbB, Patentanwälte
Braunsberger Feld 29
51429 Bergisch Gladbach / DE
Former [2013/22]polypatent BGL
Braunsberger Feld 29
51429 Bergisch Gladbach / DE
Former [2013/07]Polypatent
Braunsberger Feld 29
51429 Bergisch Gladbach / DE
Application number, filing date11712887.608.04.2011
[2016/49]
WO2011EP55552
Priority number, dateEP2010000375908.04.2010         Original published format: EP 10003759
[2013/07]
Filing languageEN
Procedural languageEN
PublicationType: A1 Application with search report
No.:WO2011124705
Date:13.10.2011
Language:EN
[2011/41]
Type: A1 Application with search report 
No.:EP2556143
Date:13.02.2013
Language:EN
The application published by WIPO in one of the EPO official languages on 13.10.2011 takes the place of the publication of the European patent application.
[2013/07]
Type: B1 Patent specification 
No.:EP2556143
Date:07.12.2016
Language:EN
[2016/49]
Search report(s)International search report - published on:EP13.10.2011
ClassificationIPC:C12N1/06, C12N15/10
[2013/07]
CPC:
C12N15/1003 (EP,US); C12N15/101 (EP,US)
Designated contracting statesAL,   AT,   BE,   BG,   CH,   CY,   CZ,   DE,   DK,   EE,   ES,   FI,   FR,   GB,   GR,   HR,   HU,   IE,   IS,   IT,   LI,   LT,   LU,   LV,   MC,   MK,   MT,   NL,   NO,   PL,   PT,   RO,   RS,   SE,   SI,   SK,   SM,   TR [2013/07]
Extension statesBANot yet paid
MENot yet paid
TitleGerman:VERFAHREN ZUM ISOLIEREN UND REINIGEN VON NUKLEINSÄUREN[2016/48]
English:METHOD FOR ISOLATING AND PURIFYING NUCLEIC ACIDS[2013/07]
French:PROCÉDÉ D'ISOLATION ET DE PURIFICATION DES ACIDES NUCLÉIQUES[2016/48]
Former [2013/07]VERFAHREN ZUR ISOLIERUNG UND REINIGUNG VON NUKLEINSÄURE
Former [2013/07]PROCÉDÉ D'ISOLEMENT ET DE PURIFICATION D'ACIDES NUCLÉIQUES
Entry into regional phase06.11.2012National basic fee paid 
06.11.2012Designation fee(s) paid 
06.11.2012Examination fee paid 
Examination procedure06.11.2012Examination requested  [2013/07]
03.06.2013Amendment by applicant (claims and/or description)
17.02.2015Despatch of a communication from the examining division (Time limit: M04)
17.06.2015Reply to a communication from the examining division
09.10.2015Despatch of a communication from the examining division (Time limit: M04)
04.02.2016Reply to a communication from the examining division
27.05.2016Communication of intention to grant the patent
04.10.2016Disapproval of the communication of intention to grant the patent by the applicant or resumption of examination proceedings by the EPO
04.10.2016Fee for grant paid
04.10.2016Fee for publishing/printing paid
26.10.2016Information about intention to grant a patent
26.10.2016Receipt of the translation of the claim(s)
Divisional application(s)The date of the Examining Division's first communication in respect of the earliest application for which a communication has been issued is  17.02.2015
Opposition(s)Opponent(s)01  07.09.2017    ADMISSIBLE
Ampersand Rechtsanwälte LLP
Haydnstraße 10
80336 München / DE
Opponent's representative
Haag, Hosea, et al, et al
Ampersand Partnerschaft von Rechtsanwälten mbB
Widenmayerstrasse 4
80538 München / DE
 [N/P]
Former [2017/46]
Opponent(s)01  07.09.2017    ADMISSIBLE
Ampersand Rechtsanwälte LLP
Haydnstraße 10
80336 München / DE
Opponent's representative
Haag, Hosea, et al, et al
Ampersand Rechtsanwälte LLP
Haydnstraße 10
80336 München / DE
Former [2017/45]
Opponent(s)01  07.09.2017   
Ampersand Rechtsanwälte LLP
Haydnstraße 10
80336 München / DE
12.12.2017Invitation to proprietor to file observations on the notice of opposition
13.04.2018Reply of patent proprietor to notice(s) of opposition
18.03.2019Cancellation of oral proceeding that was planned for 21.03.2019
21.03.2019Date of oral proceedings
18.04.2019Date of despatch of rejection of opposition
28.04.2019Legal effect of rejection of opposition [2019/36]
Fees paidRenewal fee
22.04.2013Renewal fee patent year 03
25.03.2014Renewal fee patent year 04
21.04.2015Renewal fee patent year 05
29.03.2016Renewal fee patent year 06
Opt-out from the exclusive  Tooltip
competence of the Unified
Patent Court
See the Register of the Unified Patent Court for opt-out data
Responsibility for the accuracy, completeness or quality of the data displayed under the link provided lies entirely with the Unified Patent Court.
Lapses during opposition  TooltipHU08.04.2011
AL07.12.2016
AT07.12.2016
BE07.12.2016
CY07.12.2016
CZ07.12.2016
DK07.12.2016
EE07.12.2016
ES07.12.2016
FI07.12.2016
HR07.12.2016
LT07.12.2016
LV07.12.2016
MC07.12.2016
MK07.12.2016
NL07.12.2016
PL07.12.2016
RO07.12.2016
RS07.12.2016
SE07.12.2016
SI07.12.2016
SK07.12.2016
SM07.12.2016
TR07.12.2016
BG07.03.2017
NO07.03.2017
GR08.03.2017
IS07.04.2017
PT07.04.2017
IE08.04.2017
LU08.04.2017
MT08.04.2017
[2020/33]
Former [2020/15]HU08.04.2011
AT07.12.2016
BE07.12.2016
CY07.12.2016
CZ07.12.2016
DK07.12.2016
EE07.12.2016
ES07.12.2016
FI07.12.2016
HR07.12.2016
LT07.12.2016
LV07.12.2016
MC07.12.2016
MK07.12.2016
NL07.12.2016
PL07.12.2016
RO07.12.2016
RS07.12.2016
SE07.12.2016
SI07.12.2016
SK07.12.2016
SM07.12.2016
TR07.12.2016
BG07.03.2017
NO07.03.2017
GR08.03.2017
IS07.04.2017
PT07.04.2017
IE08.04.2017
LU08.04.2017
MT08.04.2017
Former [2019/51]HU08.04.2011
AT07.12.2016
BE07.12.2016
CY07.12.2016
CZ07.12.2016
DK07.12.2016
EE07.12.2016
ES07.12.2016
FI07.12.2016
HR07.12.2016
LT07.12.2016
LV07.12.2016
MC07.12.2016
MK07.12.2016
NL07.12.2016
PL07.12.2016
RO07.12.2016
RS07.12.2016
SE07.12.2016
SI07.12.2016
SK07.12.2016
SM07.12.2016
BG07.03.2017
NO07.03.2017
GR08.03.2017
IS07.04.2017
PT07.04.2017
IE08.04.2017
LU08.04.2017
MT08.04.2017
Former [2019/46]HU08.04.2011
AT07.12.2016
BE07.12.2016
CY07.12.2016
CZ07.12.2016
DK07.12.2016
EE07.12.2016
ES07.12.2016
FI07.12.2016
HR07.12.2016
LT07.12.2016
LV07.12.2016
MC07.12.2016
NL07.12.2016
PL07.12.2016
RO07.12.2016
RS07.12.2016
SE07.12.2016
SI07.12.2016
SK07.12.2016
SM07.12.2016
BG07.03.2017
NO07.03.2017
GR08.03.2017
IS07.04.2017
PT07.04.2017
IE08.04.2017
LU08.04.2017
MT08.04.2017
Former [2019/31]HU08.04.2011
AT07.12.2016
BE07.12.2016
CZ07.12.2016
DK07.12.2016
EE07.12.2016
ES07.12.2016
FI07.12.2016
HR07.12.2016
LT07.12.2016
LV07.12.2016
MC07.12.2016
NL07.12.2016
PL07.12.2016
RO07.12.2016
RS07.12.2016
SE07.12.2016
SI07.12.2016
SK07.12.2016
SM07.12.2016
BG07.03.2017
NO07.03.2017
GR08.03.2017
IS07.04.2017
PT07.04.2017
IE08.04.2017
LU08.04.2017
MT08.04.2017
Former [2018/43]AT07.12.2016
BE07.12.2016
CZ07.12.2016
DK07.12.2016
EE07.12.2016
ES07.12.2016
FI07.12.2016
HR07.12.2016
LT07.12.2016
LV07.12.2016
MC07.12.2016
NL07.12.2016
PL07.12.2016
RO07.12.2016
RS07.12.2016
SE07.12.2016
SI07.12.2016
SK07.12.2016
SM07.12.2016
BG07.03.2017
NO07.03.2017
GR08.03.2017
IS07.04.2017
PT07.04.2017
IE08.04.2017
LU08.04.2017
MT08.04.2017
Former [2018/23]AT07.12.2016
BE07.12.2016
CZ07.12.2016
DK07.12.2016
EE07.12.2016
ES07.12.2016
FI07.12.2016
HR07.12.2016
LT07.12.2016
LV07.12.2016
MC07.12.2016
NL07.12.2016
PL07.12.2016
RO07.12.2016
RS07.12.2016
SE07.12.2016
SI07.12.2016
SK07.12.2016
SM07.12.2016
BG07.03.2017
NO07.03.2017
GR08.03.2017
IS07.04.2017
PT07.04.2017
IE08.04.2017
LU08.04.2017
Former [2018/14]AT07.12.2016
BE07.12.2016
CZ07.12.2016
DK07.12.2016
EE07.12.2016
ES07.12.2016
FI07.12.2016
HR07.12.2016
LT07.12.2016
LV07.12.2016
MC07.12.2016
NL07.12.2016
PL07.12.2016
RO07.12.2016
RS07.12.2016
SE07.12.2016
SI07.12.2016
SK07.12.2016
SM07.12.2016
BG07.03.2017
NO07.03.2017
GR08.03.2017
IS07.04.2017
PT07.04.2017
LU08.04.2017
Former [2018/06]AT07.12.2016
BE07.12.2016
CZ07.12.2016
DK07.12.2016
EE07.12.2016
ES07.12.2016
FI07.12.2016
HR07.12.2016
LT07.12.2016
LV07.12.2016
MC07.12.2016
NL07.12.2016
PL07.12.2016
RO07.12.2016
RS07.12.2016
SE07.12.2016
SI07.12.2016
SK07.12.2016
SM07.12.2016
BG07.03.2017
NO07.03.2017
GR08.03.2017
IS07.04.2017
PT07.04.2017
Former [2017/52]AT07.12.2016
BE07.12.2016
CZ07.12.2016
DK07.12.2016
EE07.12.2016
ES07.12.2016
FI07.12.2016
HR07.12.2016
LT07.12.2016
LV07.12.2016
NL07.12.2016
PL07.12.2016
RO07.12.2016
RS07.12.2016
SE07.12.2016
SI07.12.2016
SK07.12.2016
SM07.12.2016
BG07.03.2017
NO07.03.2017
GR08.03.2017
IS07.04.2017
PT07.04.2017
Former [2017/38]AT07.12.2016
BE07.12.2016
CZ07.12.2016
EE07.12.2016
ES07.12.2016
FI07.12.2016
HR07.12.2016
LT07.12.2016
LV07.12.2016
NL07.12.2016
PL07.12.2016
RO07.12.2016
RS07.12.2016
SE07.12.2016
SK07.12.2016
SM07.12.2016
BG07.03.2017
NO07.03.2017
GR08.03.2017
IS07.04.2017
PT07.04.2017
Former [2017/35]CZ07.12.2016
EE07.12.2016
ES07.12.2016
FI07.12.2016
HR07.12.2016
LT07.12.2016
LV07.12.2016
NL07.12.2016
RO07.12.2016
RS07.12.2016
SE07.12.2016
NO07.03.2017
GR08.03.2017
Former [2017/31]ES07.12.2016
FI07.12.2016
HR07.12.2016
LT07.12.2016
LV07.12.2016
NL07.12.2016
RS07.12.2016
SE07.12.2016
NO07.03.2017
GR08.03.2017
Former [2017/28]ES07.12.2016
FI07.12.2016
HR07.12.2016
LT07.12.2016
LV07.12.2016
RS07.12.2016
SE07.12.2016
NO07.03.2017
GR08.03.2017
Former [2017/12]LV07.12.2016
Cited inInternational search[XI]WO9916869  (AMERSHAM PHARM BIOTECH AB [SE], et al) [X] 1,13 * page 6; claims 1-2 * * page 12 * [I] 2-15;
 [A]WO2007050327  (GENTRA SYSTEMS INC [US], et al) [A] 1,15 * page 27 - page 28 * * page 31 *;
 [A]  - HEILIG J S ET AL, "Large-scale preparation of plasmid DNA.", CURRENT PROTOCOLS IN MOLECULAR BIOLOGY / EDITED BY FREDERICK M. AUSUBEL ... [ET AL.] MAY 2001 LNKD- PUBMED:18265046, (200105), vol. Chapter 1, ISSN 1934-3647, page UNIT1.7, XP002590534 [A] 1-15 * page 1.7.2 - page 1.7.4 *
ExaminationEP1245674
 US2006188892
by applicant   - FORCIC ET AL., J. CHROMATOGR. A, (2005), vol. 1065, no. 1, pages 115 - 120
    - HANSELLE ET AL., LEG MED (TOKYO), (2003), vol. 5 SUPP, no. 1, pages S145 - S149
    - PRODEIAIOVA ET AL., J. CHROMATOGR. A, (2004), vol. 1056, pages 43 - 48
    - RUSCONI ET AL., ANAL. BIOCHEM., (2001), vol. 295, no. 1, pages 31 - 37
    - N. G. ABOUHAIDAR, G. IVANOV, Z. NATURFORSCH, (1999), vol. 54 C, pages 542 - 548
    - D. GOLDENBERGER ET AL., GENOME RES., (1995), vol. 4, pages 368 - 370
OppositionWO9600228
 WO9916869
 EP1245674
 US2006188892
 WO2009085355
    - SHECHTER et al., "Extraction, purification and analys of histones", Nature Protocols, (20070000), vol. 2, no. 6, pages 1445 - 1457, XP009171858

DOI:   http://dx.doi.org/10.1038/nprot.2007.202
    - SCHULZ et al., "Selective adsorption of metal 1998 cations onto AOT and dodecyl sulfate films at the air/solution interface", J. Chem. Soc. Faraday Trans., (19980000), vol. 94, no. 2, pages 253 - 257, XP055417862
    - chandra mohan, "Guide for the preparation and use of buffers in biological", Buffers, (20060000), pages 1 - 38, XP055417864
    - "TRIS", Wikipedia, (20170721), pages 1 - 5, XP055417866
    - "detergents", Wikipedia, (20170722), pages 1 - 4, XP055417873
    - "product information and insrtuctions", MobiSpin, (20010100), pages 1 - 11, XP055417874
The EPO accepts no responsibility for the accuracy of data originating from other authorities; in particular, it does not guarantee that it is complete, up to date or fit for specific purposes.