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Extract from the Register of European Patents

EP About this file: EP2569305

EP2569305 - SUBSTITUTED N-HETEROARYL TETRAHYDRO-ISOQUINOLINE DERIVATIVES, PREPARATION AND THERAPEUTIC USE THEREOF [Right-click to bookmark this link]
StatusNo opposition filed within time limit
Status updated on  12.02.2016
Database last updated on 05.10.2024
Most recent event   Tooltip12.10.2018Lapse of the patent in a contracting state
New state(s): AL		published on 14.11.2018  [2018/46]
Applicant(s)For all designated states
SANOFI
54, rue La Boétie
75008 Paris / FR
[2013/12]
Inventor(s)01 / GAO, Zhongli
c/o sanofi-aventis U.S.
1041 Route 202-206
BWD-303A
Bridgewater, New Jersey 08807 / US
02 / HARTUNG, Ryan
c/o sanofi-aventis U.S.
1041 Route 202-206
BWD-303A
Bridgewater, New Jersey 08807 / US
 [2013/12]
Representative(s)Rauline, Mathilde, et al
Sanofi
Département Brevets
54, rue La Boétie
75008 Paris / FR
[2015/15]
Former [2013/12]Rauline, Mathilde, et al
Sanofi
Département Brevets
54 rue La Boétie
75008 Paris / FR
Application number, filing date11731174.610.05.2011
WO2011US35835
Priority number, dateFR2010006106422.12.2010         Original published format: FR 1061064
US20100333385P11.05.2010         Original published format: US 333385 P
[2013/12]
Filing languageEN
Procedural languageEN
PublicationType: A1 Application with search report
No.:WO2011143155
Date:17.11.2011
Language:EN
[2011/46]
Type: A1 Application with search report 
No.:EP2569305
Date:20.03.2013
Language:EN
The application published by WIPO in one of the EPO official languages on 17.11.2011 takes the place of the publication of the European patent application.
[2013/12]
Type: B1 Patent specification 
No.:EP2569305
Date:08.04.2015
Language:EN
[2015/15]
Search report(s)International search report - published on:EP17.11.2011
ClassificationIPC:C07D401/14, C07D403/14, C07D413/14, A61K31/4709, A61P25/00
[2013/12]
CPC:
C07D401/14 (EP,US); A61P21/00 (EP); A61P25/00 (EP);
A61P25/08 (EP); A61P25/10 (EP); A61P25/12 (EP);
A61P25/14 (EP); A61P25/16 (EP); A61P25/18 (EP);
A61P25/20 (EP); A61P25/22 (EP); A61P25/24 (EP);
A61P25/28 (EP); A61P3/04 (EP); A61P43/00 (EP);
C07D403/14 (EP,US); C07D413/14 (EP,US) (-)
Designated contracting statesAL,   AT,   BE,   BG,   CH,   CY,   CZ,   DE,   DK,   EE,   ES,   FI,   FR,   GB,   GR,   HR,   HU,   IE,   IS,   IT,   LI,   LT,   LU,   LV,   MC,   MK,   MT,   NL,   NO,   PL,   PT,   RO,   RS,   SE,   SI,   SK,   SM,   TR [2013/12]
Extension statesBA11.02.2013
ME11.02.2013
TitleGerman:SUBSTITUIERTE N-HETEROARYL-TETRAHYDRO-ISOCHINOLIN-DERIVATE, IHRE HERSTELLUNG UND THERAPEUTISCHE VERWENDUNG[2013/12]
English:SUBSTITUTED N-HETEROARYL TETRAHYDRO-ISOQUINOLINE DERIVATIVES, PREPARATION AND THERAPEUTIC USE THEREOF[2013/12]
French:DÉRIVÉS DE N-HÉTÉROARYL TÉTRAHYDRO-ISOQUINOLINES SUBSTITUÉES, PROCÉDÉ DE PRÉPARATION ET USAGE THÉRAPEUTIQUE ASSOCIÉS[2013/12]
Entry into regional phase11.12.2012National basic fee paid 
11.12.2012Designation fee(s) paid 
11.12.2012Examination fee paid 
Examination procedure11.12.2012Examination requested  [2013/12]
23.09.2013Despatch of communication that the application is deemed to be withdrawn, reason: reply to the Extended European Search Report/Written Opinion of the International Searching Authority/International Preliminary Examination Report/Supplementary international search report not received in time
21.11.2013Amendment by applicant (claims and/or description)
29.10.2014Communication of intention to grant the patent
25.02.2015Fee for grant paid
25.02.2015Fee for publishing/printing paid
25.02.2015Receipt of the translation of the claim(s)
Divisional application(s)The date of the Examining Division's first communication in respect of the earliest application for which a communication has been issued is  29.10.2014
Opposition(s)11.01.2016No opposition filed within time limit [2016/11]
Request for further processing for:21.11.2013Request for further processing filed
21.11.2013Full payment received (date of receipt of payment)
Request granted
02.12.2013Decision despatched
Fees paidRenewal fee
10.05.2013Renewal fee patent year 03
27.03.2014Renewal fee patent year 04
Opt-out from the exclusive  Tooltip
competence of the Unified
Patent Court		 See the Register of the Unified Patent Court for opt-out data
Responsibility for the accuracy, completeness or quality of the data displayed under the link provided lies entirely with the Unified Patent Court.
Lapses during opposition  TooltipHU10.05.2011
AL08.04.2015
AT08.04.2015
BE08.04.2015
BG08.04.2015
CY08.04.2015
CZ08.04.2015
DK08.04.2015
EE08.04.2015
ES08.04.2015
FI08.04.2015
HR08.04.2015
IT08.04.2015
LT08.04.2015
LV08.04.2015
MC08.04.2015
MK08.04.2015
MT08.04.2015
NL08.04.2015
PL08.04.2015
RO08.04.2015
RS08.04.2015
SE08.04.2015
SI08.04.2015
SK08.04.2015
SM08.04.2015
TR08.04.2015
IE10.05.2015
LU10.05.2015
CH31.05.2015
LI31.05.2015
NO08.07.2015
GR09.07.2015
IS08.08.2015
PT10.08.2015
[2018/46]
Former [2018/31]HU10.05.2011
AT08.04.2015
BE08.04.2015
BG08.04.2015
CY08.04.2015
CZ08.04.2015
DK08.04.2015
EE08.04.2015
ES08.04.2015
FI08.04.2015
HR08.04.2015
IT08.04.2015
LT08.04.2015
LV08.04.2015
MC08.04.2015
MK08.04.2015
MT08.04.2015
NL08.04.2015
PL08.04.2015
RO08.04.2015
RS08.04.2015
SE08.04.2015
SI08.04.2015
SK08.04.2015
SM08.04.2015
TR08.04.2015
IE10.05.2015
LU10.05.2015
CH31.05.2015
LI31.05.2015
NO08.07.2015
GR09.07.2015
IS08.08.2015
PT10.08.2015
Former [2018/02]HU10.05.2011
AT08.04.2015
BE08.04.2015
BG08.04.2015
CY08.04.2015
CZ08.04.2015
DK08.04.2015
EE08.04.2015
ES08.04.2015
FI08.04.2015
HR08.04.2015
IT08.04.2015
LT08.04.2015
LV08.04.2015
MC08.04.2015
MT08.04.2015
NL08.04.2015
PL08.04.2015
RO08.04.2015
RS08.04.2015
SE08.04.2015
SI08.04.2015
SK08.04.2015
SM08.04.2015
TR08.04.2015
IE10.05.2015
LU10.05.2015
CH31.05.2015
LI31.05.2015
NO08.07.2015
GR09.07.2015
IS08.08.2015
PT10.08.2015
Former [2017/38]HU10.05.2011
AT08.04.2015
BE08.04.2015
BG08.04.2015
CY08.04.2015
CZ08.04.2015
DK08.04.2015
EE08.04.2015
ES08.04.2015
FI08.04.2015
HR08.04.2015
IT08.04.2015
LT08.04.2015
LV08.04.2015
MC08.04.2015
MT08.04.2015
NL08.04.2015
PL08.04.2015
RO08.04.2015
RS08.04.2015
SE08.04.2015
SI08.04.2015
SK08.04.2015
SM08.04.2015
TR08.04.2015
IE10.05.2015
CH31.05.2015
LI31.05.2015
NO08.07.2015
GR09.07.2015
IS08.08.2015
PT10.08.2015
Former [2017/03]AT08.04.2015
BE08.04.2015
CZ08.04.2015
DK08.04.2015
EE08.04.2015
ES08.04.2015
FI08.04.2015
HR08.04.2015
IT08.04.2015
LT08.04.2015
LV08.04.2015
MC08.04.2015
MT08.04.2015
NL08.04.2015
PL08.04.2015
RO08.04.2015
RS08.04.2015
SI08.04.2015
SK08.04.2015
IE10.05.2015
CH31.05.2015
LI31.05.2015
NO08.07.2015
GR09.07.2015
IS08.08.2015
PT10.08.2015
Former [2016/37]AT08.04.2015
BE08.04.2015
CZ08.04.2015
DK08.04.2015
EE08.04.2015
ES08.04.2015
FI08.04.2015
HR08.04.2015
IT08.04.2015
LT08.04.2015
LV08.04.2015
MC08.04.2015
NL08.04.2015
PL08.04.2015
RO08.04.2015
RS08.04.2015
SI08.04.2015
SK08.04.2015
IE10.05.2015
CH31.05.2015
LI31.05.2015
NO08.07.2015
GR09.07.2015
IS08.08.2015
PT10.08.2015
Former [2016/24]AT08.04.2015
CZ08.04.2015
DK08.04.2015
EE08.04.2015
ES08.04.2015
FI08.04.2015
HR08.04.2015
IT08.04.2015
LT08.04.2015
LV08.04.2015
MC08.04.2015
NL08.04.2015
PL08.04.2015
RO08.04.2015
RS08.04.2015
SI08.04.2015
SK08.04.2015
IE10.05.2015
CH31.05.2015
LI31.05.2015
NO08.07.2015
GR09.07.2015
IS08.08.2015
PT10.08.2015
Former [2016/20]AT08.04.2015
CZ08.04.2015
DK08.04.2015
EE08.04.2015
ES08.04.2015
FI08.04.2015
HR08.04.2015
IT08.04.2015
LT08.04.2015
LV08.04.2015
MC08.04.2015
NL08.04.2015
PL08.04.2015
RO08.04.2015
RS08.04.2015
SK08.04.2015
IE10.05.2015
CH31.05.2015
LI31.05.2015
NO08.07.2015
GR09.07.2015
IS08.08.2015
PT10.08.2015
Former [2016/10]AT08.04.2015
CZ08.04.2015
DK08.04.2015
EE08.04.2015
ES08.04.2015
FI08.04.2015
HR08.04.2015
IT08.04.2015
LT08.04.2015
LV08.04.2015
MC08.04.2015
NL08.04.2015
PL08.04.2015
RO08.04.2015
RS08.04.2015
SK08.04.2015
CH31.05.2015
LI31.05.2015
NO08.07.2015
GR09.07.2015
IS08.08.2015
PT10.08.2015
Former [2016/09]AT08.04.2015
DK08.04.2015
EE08.04.2015
ES08.04.2015
FI08.04.2015
HR08.04.2015
IT08.04.2015
LT08.04.2015
LV08.04.2015
MC08.04.2015
NL08.04.2015
RS08.04.2015
CH31.05.2015
LI31.05.2015
NO08.07.2015
GR09.07.2015
IS08.08.2015
PT10.08.2015
Former [2016/08]AT08.04.2015
DK08.04.2015
ES08.04.2015
FI08.04.2015
HR08.04.2015
IT08.04.2015
LT08.04.2015
LV08.04.2015
NL08.04.2015
RS08.04.2015
CH31.05.2015
LI31.05.2015
NO08.07.2015
GR09.07.2015
IS08.08.2015
PT10.08.2015
Former [2016/07]AT08.04.2015
DK08.04.2015
ES08.04.2015
FI08.04.2015
HR08.04.2015
LT08.04.2015
LV08.04.2015
NL08.04.2015
RS08.04.2015
CH31.05.2015
LI31.05.2015
NO08.07.2015
GR09.07.2015
IS08.08.2015
PT10.08.2015
Former [2016/06]AT08.04.2015
ES08.04.2015
FI08.04.2015
HR08.04.2015
LT08.04.2015
LV08.04.2015
NL08.04.2015
RS08.04.2015
CH31.05.2015
LI31.05.2015
NO08.07.2015
GR09.07.2015
IS08.08.2015
PT10.08.2015
Former [2015/51]AT08.04.2015
ES08.04.2015
FI08.04.2015
HR08.04.2015
LT08.04.2015
LV08.04.2015
NL08.04.2015
RS08.04.2015
NO08.07.2015
GR09.07.2015
IS08.08.2015
PT10.08.2015
Former [2015/50]ES08.04.2015
FI08.04.2015
HR08.04.2015
LT08.04.2015
LV08.04.2015
NL08.04.2015
RS08.04.2015
NO08.07.2015
GR09.07.2015
IS08.08.2015
PT10.08.2015
Former [2015/49]ES08.04.2015
FI08.04.2015
HR08.04.2015
LT08.04.2015
LV08.04.2015
NL08.04.2015
RS08.04.2015
NO08.07.2015
GR09.07.2015
PT10.08.2015
Former [2015/42]NL08.04.2015
Cited inInternational search[A]WO2005087746  (GLAXO GROUP LTD [GB], et al) [A] 1-15 * the whole document *;
 [A]WO2009052062  (SANOFI AVENTIS [FR], et al) [A] 1-15 * the whole document *;
 [A]WO2010007382  (TAKEDA PHARMACEUTICAL [JP], et al) [A] 1-15 * the whole document *
by applicantUS7223788
    - HANCOCK, BIOCHEM. PHARMACOL., (20060414), vol. 71, no. 8, pages 1103 - 13
    - ESBENSHADE ET AL., MOL INTERV., (200604), vol. 6, no. 2, pages 77 - 88,59
    - D. W. OLD, J.P. WOLFE, S. L. BUCHWALD, J. AM. CHEM. SOC., (1998), vol. 120, pages 9722 - 9723
    - J. P. WOLFE, H. TOMORI, J. P. SADIGHI, J. YIN, S. L. BUCHWALD, J. ORG. CHEM., (2000), vol. 65, pages 1158 - 1174
    - VAN DER POEL A.M, NOACH E.J.K, MICZEK K.A, "Temporal patterning of ultrasonic distress calls in the adult rat: effects of morphine and benzodiazepines", PSYCHOPHARMACOLOGY, (1989), vol. 97, pages 147 - 8
    - PORSOLT ET AL., "Depression: a new animal model sensitive to antidepressant treatments", NATURE, (1977), vol. 266, pages 730 - 2
The EPO accepts no responsibility for the accuracy of data originating from other authorities; in particular, it does not guarantee that it is complete, up to date or fit for specific purposes.