Deutsch English Français

Contact

EP2582293

European procedure

Quick help

Maintenance news

Scheduled maintenance

Regular maintenance outages:
between 05.00 and 05.15 hrs CET (Monday to Sunday).

Other outages
Availability

2022.02.11

More...

News flashes

News Flashes

New version of the European Patent Register – SPC proceedings information in the Unitary Patent Register.

2024-07-24

More...

Extract from the Register of European Patents

EP About this file: EP2582293

EP2582293 - METHOD AND APPARATUS FOR DETERMINING AN AUTOFLUORESCENCE VALUE OF SKIN TISSUE. [Right-click to bookmark this link]
Status	No opposition filed within time limit Status updated on 24.02.2017 Database last updated on 04.11.2024
Most recent event Tooltip	12.10.2018	Lapse of the patent in a contracting state New state(s): AL	published on 14.11.2018 [2018/46]
Applicant(s)	For all designated states DiagnOptics Holding B.V. Aarhusweg 4-9 9723 JJ Groningen / NL
	[2015/38]
Former [2015/20]	For all designated states DiagnOptics Holding B.V. Aarhusweg 4 9723 JJ Groningen / NL
Former [2013/17]	For all designated states DiagnOptics Holding B.V. L.J. Zielstraweg 1 9713 GX Groningen / NL
Inventor(s)	01 / GRAAFF, Reindert Fultsemaheerd 16 NL-9736 CN Groningen / NL
	02 / KOETSIER, Marten c/o Aarhusweg 4-9 9723 JJ Groningen / NL
	03 / SMIT, Andries, Jan Lekstraat 14 NL-9725 KM Groningen / NL
	04 / VAN DEN BERG, Bartholomeus, Adrianus H.J. Koenenstraat 9 NL-2012 BA Haarlem / NL
	05 / VAN DER ZEE, Pieter Kromme Riet 5 NL-9746 PV Groningen / NL
	[2015/38]
Former [2013/17]	01 / GRAAFF, Reindert Fultsemaheerd 16 NL-9736 CN Groningen / NL
	02 / KOETSIER, Marten van Lenneplaan 373 NL-9721 PM Groningen / NL
	03 / SMIT, Andries, Jan Lekstraat 14 NL-9725 KM Groningen / NL
	04 / VAN DEN BERG, Bartholomeus, Adrianus H.J. Koenenstraat 9 NL-2012 BA Haarlem / NL
	05 / VAN DER ZEE, Pieter Kromme Riet 5 NL-9746 PV Groningen / NL
Representative(s)	V.O. P.O. Box 87930 2508 DH Den Haag / NL
	[2016/16]
Former [2013/17]	Jansen, Cornelis Marinus, et al VEREENIGDE Johan de Wittlaan 7 2517 JR Den Haag / NL
Application number, filing date	11743656.8	20.06.2011
	[2016/16]
	WO2011NL00051
Priority number, date	NL20102004920	18.06.2010 Original published format: NL 2004920
	[2013/17]
Filing language	EN
Procedural language	EN
Publication	Type:	A2 Application without search report
	No.:	WO2011159148
	Date:	22.12.2011
	Language:	EN
	[2011/51]
	Type:	A2 Application without search report
	No.:	EP2582293
	Date:	24.04.2013
	Language:	EN
	The application published by WIPO in one of the EPO official languages on 22.12.2011 takes the place of the publication of the European patent application.
	[2013/17]
	Type:	B1 Patent specification
	No.:	EP2582293
	Date:	20.04.2016
	Language:	EN
	[2016/16]
Search report(s)	International search report - published on:	EP	05.04.2012
Classification	IPC:	A61B5/103, A61B5/00	[2013/17]
	CPC:	A61B5/0059 (EP,US); A61B5/0071 (US); A61B5/14532 (US); A61B5/441 (EP,US); A61B5/7225 (US); A61B5/7278 (US); (+) A61B5/7275 (EP,US) (-)
Designated contracting states	AL, AT, BE, BG, CH, CY, CZ, DE, DK, EE, ES, FI, FR, GB, GR, HR, HU, IE, IS, IT, LI, LT, LU, LV, MC, MK, MT, NL, NO, PL, PT, RO, RS, SE, SI, SK, SM, TR [2013/17]
Extension states	BA	Not yet paid
	ME	Not yet paid
Title	German:	VERFAHREN UND VORRICHTUNG ZUR BESTIMMUNG EINES AUTOFLUORESZENZWERTES VON HAUTGEWEBE	[2013/17]
	English:	METHOD AND APPARATUS FOR DETERMINING AN AUTOFLUORESCENCE VALUE OF SKIN TISSUE.	[2013/17]
	French:	PROCÉDÉ ET APPAREIL PERMETTANT DE DÉTERMINER LA VALEUR D'AUTOFLUORESCENCE D'UN TISSU CUTANÉ	[2013/17]
Entry into regional phase	18.01.2013	National basic fee paid
	18.01.2013	Designation fee(s) paid
	18.01.2013	Examination fee paid
Examination procedure	18.01.2013	Examination requested [2013/17]
	23.09.2013	Amendment by applicant (claims and/or description)
	07.02.2014	Despatch of a communication from the examining division (Time limit: M04)
	17.06.2014	Reply to a communication from the examining division
	06.03.2015	Communication of intention to grant the patent
	16.07.2015	Disapproval of the communication of intention to grant the patent by the applicant or resumption of examination proceedings by the EPO
	02.10.2015	Communication of intention to grant the patent
	10.02.2016	Fee for grant paid
	10.02.2016	Fee for publishing/printing paid
	26.02.2016	Information about intention to grant a patent
	26.02.2016	Receipt of the translation of the claim(s)
Divisional application(s)	The date of the Examining Division's first communication in respect of the earliest application for which a communication has been issued is 07.02.2014
Opposition(s)	23.01.2017	No opposition filed within time limit [2017/13]
Fees paid	Renewal fee
	17.06.2013	Renewal fee patent year 03
	31.03.2014	Renewal fee patent year 04
	29.05.2015	Renewal fee patent year 05
Opt-out from the exclusive Tooltip competence of the Unified Patent Court	See the Register of the Unified Patent Court for opt-out data
	Responsibility for the accuracy, completeness or quality of the data displayed under the link provided lies entirely with the Unified Patent Court.
Lapses during opposition Tooltip	HU	20.06.2011
	AL	20.04.2016
	AT	20.04.2016
	BE	20.04.2016
	BG	20.04.2016
	CY	20.04.2016
	CZ	20.04.2016
	DK	20.04.2016
	EE	20.04.2016
	FI	20.04.2016
	HR	20.04.2016
	IS	20.04.2016
	LT	20.04.2016
	LV	20.04.2016
	MC	20.04.2016
	MK	20.04.2016
	PL	20.04.2016
	RO	20.04.2016
	RS	20.04.2016
	SE	20.04.2016
	SI	20.04.2016
	SK	20.04.2016
	SM	20.04.2016
	TR	20.04.2016
	LU	20.06.2016
	MT	30.06.2016
	NO	20.07.2016
	GR	21.07.2016
	PT	22.08.2016
	[2018/46]
Former [2018/38]	HU	20.06.2011
	AT	20.04.2016
	BE	20.04.2016
	BG	20.04.2016
	CY	20.04.2016
	CZ	20.04.2016
	DK	20.04.2016
	EE	20.04.2016
	FI	20.04.2016
	HR	20.04.2016
	IS	20.04.2016
	LT	20.04.2016
	LV	20.04.2016
	MC	20.04.2016
	MK	20.04.2016
	PL	20.04.2016
	RO	20.04.2016
	RS	20.04.2016
	SE	20.04.2016
	SI	20.04.2016
	SK	20.04.2016
	SM	20.04.2016
	TR	20.04.2016
	LU	20.06.2016
	MT	30.06.2016
	NO	20.07.2016
	GR	21.07.2016
	PT	22.08.2016
Former [2018/31]	HU	20.06.2011
	AT	20.04.2016
	BE	20.04.2016
	CY	20.04.2016
	CZ	20.04.2016
	DK	20.04.2016
	EE	20.04.2016
	FI	20.04.2016
	HR	20.04.2016
	IS	20.04.2016
	LT	20.04.2016
	LV	20.04.2016
	MC	20.04.2016
	MK	20.04.2016
	PL	20.04.2016
	RO	20.04.2016
	RS	20.04.2016
	SE	20.04.2016
	SI	20.04.2016
	SK	20.04.2016
	SM	20.04.2016
	TR	20.04.2016
	LU	20.06.2016
	MT	30.06.2016
	NO	20.07.2016
	GR	21.07.2016
	PT	22.08.2016
Former [2018/29]	HU	20.06.2011
	AT	20.04.2016
	BE	20.04.2016
	CY	20.04.2016
	CZ	20.04.2016
	DK	20.04.2016
	EE	20.04.2016
	FI	20.04.2016
	HR	20.04.2016
	LT	20.04.2016
	LV	20.04.2016
	MC	20.04.2016
	MK	20.04.2016
	PL	20.04.2016
	RO	20.04.2016
	RS	20.04.2016
	SE	20.04.2016
	SI	20.04.2016
	SK	20.04.2016
	SM	20.04.2016
	TR	20.04.2016
	LU	20.06.2016
	NO	20.07.2016
	GR	21.07.2016
	PT	22.08.2016
Former [2018/28]	HU	20.06.2011
	AT	20.04.2016
	BE	20.04.2016
	CY	20.04.2016
	CZ	20.04.2016
	DK	20.04.2016
	EE	20.04.2016
	FI	20.04.2016
	HR	20.04.2016
	LT	20.04.2016
	LV	20.04.2016
	MC	20.04.2016
	MK	20.04.2016
	PL	20.04.2016
	RO	20.04.2016
	RS	20.04.2016
	SE	20.04.2016
	SI	20.04.2016
	SK	20.04.2016
	SM	20.04.2016
	NO	20.07.2016
	GR	21.07.2016
	PT	22.08.2016
Former [2017/37]	AT	20.04.2016
	BE	20.04.2016
	CZ	20.04.2016
	DK	20.04.2016
	EE	20.04.2016
	FI	20.04.2016
	HR	20.04.2016
	LT	20.04.2016
	LV	20.04.2016
	MC	20.04.2016
	PL	20.04.2016
	RO	20.04.2016
	RS	20.04.2016
	SE	20.04.2016
	SI	20.04.2016
	SK	20.04.2016
	SM	20.04.2016
	NO	20.07.2016
	GR	21.07.2016
	PT	22.08.2016
Former [2017/11]	AT	20.04.2016
	BE	20.04.2016
	CZ	20.04.2016
	DK	20.04.2016
	EE	20.04.2016
	FI	20.04.2016
	HR	20.04.2016
	LT	20.04.2016
	LV	20.04.2016
	MC	20.04.2016
	PL	20.04.2016
	RO	20.04.2016
	RS	20.04.2016
	SE	20.04.2016
	SK	20.04.2016
	SM	20.04.2016
	NO	20.07.2016
	GR	21.07.2016
	PT	22.08.2016
Former [2017/10]	AT	20.04.2016
	BE	20.04.2016
	CZ	20.04.2016
	DK	20.04.2016
	EE	20.04.2016
	FI	20.04.2016
	HR	20.04.2016
	LT	20.04.2016
	LV	20.04.2016
	MC	20.04.2016
	PL	20.04.2016
	RO	20.04.2016
	RS	20.04.2016
	SE	20.04.2016
	SK	20.04.2016
	NO	20.07.2016
	GR	21.07.2016
	PT	22.08.2016
Former [2017/09]	AT	20.04.2016
	BE	20.04.2016
	CZ	20.04.2016
	DK	20.04.2016
	EE	20.04.2016
	FI	20.04.2016
	HR	20.04.2016
	LT	20.04.2016
	LV	20.04.2016
	MC	20.04.2016
	PL	20.04.2016
	RO	20.04.2016
	RS	20.04.2016
	SE	20.04.2016
	NO	20.07.2016
	GR	21.07.2016
	PT	22.08.2016
Former [2017/07]	AT	20.04.2016
	BE	20.04.2016
	DK	20.04.2016
	FI	20.04.2016
	HR	20.04.2016
	LT	20.04.2016
	LV	20.04.2016
	MC	20.04.2016
	PL	20.04.2016
	RS	20.04.2016
	SE	20.04.2016
	NO	20.07.2016
	GR	21.07.2016
	PT	22.08.2016
Former [2017/03]	AT	20.04.2016
	BE	20.04.2016
	FI	20.04.2016
	HR	20.04.2016
	LT	20.04.2016
	LV	20.04.2016
	PL	20.04.2016
	RS	20.04.2016
	SE	20.04.2016
	NO	20.07.2016
	GR	21.07.2016
	PT	22.08.2016
Former [2016/52]	AT	20.04.2016
	FI	20.04.2016
	HR	20.04.2016
	LT	20.04.2016
	LV	20.04.2016
	PL	20.04.2016
	RS	20.04.2016
	SE	20.04.2016
	NO	20.07.2016
	GR	21.07.2016
	PT	22.08.2016
Former [2016/51]	AT	20.04.2016
	FI	20.04.2016
	HR	20.04.2016
	LT	20.04.2016
	LV	20.04.2016
	PL	20.04.2016
	RS	20.04.2016
	NO	20.07.2016
	GR	21.07.2016
	PT	22.08.2016
Former [2016/50]	AT	20.04.2016
	FI	20.04.2016
	HR	20.04.2016
	LT	20.04.2016
	LV	20.04.2016
	PL	20.04.2016
	RS	20.04.2016
	NO	20.07.2016
Former [2016/49]	FI	20.04.2016
	LT	20.04.2016
	PL	20.04.2016
	NO	20.07.2016
Former [2016/46]	LT	20.04.2016
	NO	20.07.2016
Cited in	International search	[XDI]WO0122869 (JIPJAP B V [NL], et al) [XD] 1-3,5,8,9,12,14,17,18,20 * abstract * * page 1, lines 3-8 * * page 2, lines 3-12 * * page 5, line 1 - page 7, line 18 * * page 11, line 1 - page 12, line 29 * * page 15, line 1 - page 16, line 8; figure 4 * [I] 4,6,7,19;
		[X]WO2005045393 (INLIGHT SOLUTIONS INC [US], et al) [X] 1,17,20 * abstract * * paragraphs [0016] , [0022] , [0025] * * paragraphs [0027] - [0030] - [0033] , [0046] , [0058] *;
		[X]US2007276199 (EDIGER MARWOOD N [US], et al) [X] 1,17,20 * paragraphs [0002] , [0009] - [0012] - [0052] , [0055] , [0066] , [0091] , [0092]; claims 1,30-34 *;
		[XI]WO2009086474 (VERALIGHT INC [US], et al) [X] 1,20-22 * abstract * [I] 23,24;
		[X]JP2009247430 (POLA CHEM IND INC) [X] 1,17,20 * abstract ** paragraphs [0010] , [0011] , [0013] , [0014] , [0016] - [0018] - [0020] , [0025] , [0028] *
	by applicant	WO0122869
		- M. KOETSIER ET AL., Skin color independent assessment of aging using skin autofluorescence, OPTICS EXPRESS (@ 2010 OPTICAL SOCIETY OF AMERICA, INC.
		- S. ALALUF, D. ATKINS, K. BARRETT, M. BLOUNT, N. CARTER, A. HEATH, "Ethnic variation in melanin content and composition in photoexposed and photoprotected human skin", PIGMENT CELL RESEARCH / SPONSORED BY THE EUROPEAN SOCIETY FOR PIGMENT CELL RESEARCH AND THE INTERNATIONAL PIGMENT CELL SOCIETY, (2002), vol. 15, pages 112 - 8
		- R.R. ANDERSON, J.A. PARRISH, "The optics of human skin", J INVEST DERMATOL, (1981), vol. 77, doi:doi:10.1111/1523-1747.ep12479191, pages 13 - 19, XP000572810 DOI: http://dx.doi.org/10.1111/1523-1747.ep12479191
		- L. BACHMANN, D. ZEZELL, A. RIBEIRO, L. GOMES, A. ITO, "Fluorescence spectroscopy of biological tissues-A review", APPLIED SPECTROSCOPY REVIEWS, (2006), vol. 41, pages 575 - 590
		- G.S. BARSH, "What controls variation in human skin color?", PLOS BIOL, (2003), vol. 1, page E27
		- R. CHEN, Z. HUANG, H. LUI, I. HAMZAVI, D.I. MCLEAN, S. XIE, H. ZENG, "Monte Carlo simulation of cutaneous reflectance and fluorescence measurements--the effect of melanin contents and localization", J PHOTOCHEM PHOTOBIOL B, (2007), vol. 86, doi:doi:10.1016/j.jphotobiol.2006.11.001, pages 219 - 226, XP005867356 DOI: http://dx.doi.org/10.1016/j.jphotobiol.2006.11.001
		- JM. COREMANS, C. INCE, H.A. BRUINING, G.J. PUPPELS, "Semi-)quantitative analysis of reduced nicotinamide adenine dinucleotide fluorescence images of blood-perfused rat heart", BIOPHYS J, (1997), vol. 72, pages 1849 - 1860
		- J.B. DAWSON, D.J. BARKER, D.J. ELLIS, E. GRASSAM, J.A. COTTERILL, G.W. FISHER, J.W. FEATHER, "A theoretical and experimental study of light absorption and scattering by in vivo skin", PHYS MED BIOL, (1980), vol. 25, doi:doi:10.1088/0031-9155/25/4/008, pages 695 - 709, XP020022280 DOI: http://dx.doi.org/10.1088/0031-9155/25/4/008
		- N.C. DEN HOLLANDER, D.J. MULDER, R. GRAAFF, S.R. THORPE, J.W. BAYNES, G.P. SMIT, A.J. SMIT, "Advanced glycation end products and the absence of premature atherosclerosis in glycogen storage disease Ia", J INHERIT METAB DIS, (2007), vol. 30, doi:doi:10.1007/s10545-007-0507-0, pages 916 - 923, XP019548947 DOI: http://dx.doi.org/10.1007/s10545-007-0507-0
		- J.W. FEATHER, M. HAJIZADEH-SAFFAR, G. LESLIE, J.B. DAWSON, "A portable scanning reflectance spectrophotometer using visible wavelengths for the rapid measurement of skin pigments", PHYS MED BIOL, (1989), vol. 34, doi:doi:10.1088/0031-9155/34/7/002, pages 807 - 820, XP000141238 DOI: http://dx.doi.org/10.1088/0031-9155/34/7/002
		- K.M. KATIKA, L. PILON, "Steady-state directional diffuse reflectance and fluorescence of human skin", APPL OPT, (2006), vol. 45, doi:doi:10.1364/AO.45.004174, pages 4174 - 4183, XP001243978 DOI: http://dx.doi.org/10.1364/AO.45.004174
		- M. KOETSIER, H.L. LUTGERS, A.J. SMIT, T.P. LINKS, R.D. VRIES, R.O. GANS, G. RAKHORST, R. GRAAFF, "Skin autofluorescence for the risk assessment of chronic complications in diabetes: a broad excitation range is sufficient", OPT EXPRESS, (2009), vol. 17, pages 509 - 519
		- M. KOETSIER, H.L. LUTGERS, C. DE JONGE, T.P. LINKS, A.J. SMIT, R. GRAAFF, "Reference values of skin autofluorescence", DIABETES TECHNOL THER, (2010), vol. 12, pages 399 - 403
		- N. KOLLIAS, A. BAQER, "Spectroscopic characteristics of human melanin in vivo", J INVEST DERMATOL, (1985), vol. 85, doi:doi:10.1111/1523-1747.ep12275011, pages 38 - 42, XP002303195 DOI: http://dx.doi.org/10.1111/1523-1747.ep12275011
		- N. KOLLIAS, A.H. BAQER, "Absorption mechanisms of human melanin in the visible, 400-720 nm", J INVEST DERMATOL, (1987), vol. 89, pages 384 - 388
		- N. KOLLIAS, G. ZONIOS, G.N. STAMATAS, "Fluorescence spectroscopy of skin", VIB SPECTROSC, (2002), vol. 28, pages 17 - 23
		- H.L. LUTGERS, E.G. GERRITS, R. GRAAFF, T.P. LINKS, W.J. SLUITER, R.O. GANS, H.J. BILO, A.J. SMIT, "Skin autofluorescence provides additional information to the UK Prospective Diabetes Study (UKPDS) risk score for the estimation of cardiovascular prognosis in type 2 diabetes mellitus", DIABETOLOGIA, (2009), vol. 52, pages 789 - 797, XP019698583
		- C. MAGNAIN, M. ELIAS, J. FRIGERIO, "Skin color modeling using the radiative transfer equation solved by the auxiliary function method", JOURNAL OF THE OPTICAL SOCIETY OF AMERICA. A, OPTICS, IMAGE SCIENCE, AND VISION, (2007), vol. 24, pages 2196 - 205
		- T. MATSUMOTO, T. TSURUMOTO, H. BABA, M. OSAKI, H. ENOMOTO, A. YONEKURA, H. SHINDO, T. MIYATA, "Measurement of advanced glycation endproducts in skin of patients with rheumatoid arthritis, osteoarthritis, and dialysis-related spondyloarthropathy using non-invasive methods", RHEUMATOL INT, (2007), vol. 28, doi:doi:10.1007/s00296-007-0408-4, pages 157 - 160, XP019561645 DOI: http://dx.doi.org/10.1007/s00296-007-0408-4
		- R. MEERWALDT, R. GRAAFF, P.H. OOMEN, T.P. LINKS, J.J. JAGER, N.L. ALDERSON, S.R. THORPE, J.W. BAYNES, R.O. GANS, A.J. SMIT, "Simple non-invasive assessment of advanced glycation endproduct accumulation", DIABETOLOGIA, (2004), vol. 47, pages 1324 - 1330
		- R. MEERWALDT, J.W. HARTOG, R. GRAAFF, R.J. HUISMAN, T.P. LINKS, N.C. DEN HOLLANDER, S.R. THORPE, J.W. BAYNES, G. NAVIS, R.O. GANS, "Skin autofluorescence, a measure of cumulative metabolic stress and advanced glycation end products, predicts mortality in hemodialysis patients", JAM SOC NEPHROL, (2005), vol. 16, pages 3687 - 3693
		- M. MONAMI, C. LAMANNA, F. GORI, F. BARTALUCCI, N. MARCHIONNI, E. MANNUCCI, "Skin autofluorescence in type 2 diabetes: beyond blood glucose", DIABETES RES CLIN PRACT, (2008), vol. 79, doi:doi:10.1016/j.diabres.2007.07.007, pages 56 - 60, XP022408411 DOI: http://dx.doi.org/10.1016/j.diabres.2007.07.007
		- D.J. MULDER, P.L. VAN HAELST, S. GROSS, K. DE LEEUW, J. BIJZET, R. GRAAFF, R.O. GANS, F. ZIJLSTRA, A.J. SMIT, "Skin autofluorescence is elevated in patients with stable coronary artery disease and is associated with serum levels of neopterin and the soluble receptor for advanced glycation end products", ATHEROSCLEROSIS, (2008), vol. 197, doi:doi:10.1016/j.atherosclerosis.2007.03.027, pages 217 - 223, XP022493955 DOI: http://dx.doi.org/10.1016/j.atherosclerosis.2007.03.027
		- D.J. MULDER, T.V. WATER, H.L. LUTGERS, R. GRAAFF, R.O. GANS, F. ZIJLSTRA, A.J. SMIT, "Skin autofluorescence, a novel marker for glycemic and oxidative stress-derived advanced glycation endproducts: an overview of current clinical studies, evidence, and limitations", DIABETES TECHNOL THER, (2006), vol. 8, pages 523 - 535
		- R. NA, I.M. STENDER, M. HENRIKSEN, H.C. WULF, "Autofluorescence of human skin is age-related after correction for skin pigmentation and redness", J INVEST DERMATOL, (2001), vol. 116, pages 536 - 540
		- K.P. NIELSEN, L. ZHAO, G.A. RYZHIKOV, M.S. BIRYULINA, E.R. SOMMERSTEN, J.J. STAMNES, K. STAMNES, J. MOAN, "Retrieval of the physiological state of human skin from UV-Vis reflectance spectra - a feasibility study", J PHOTOCHEM PHOTOBIOL B, (2008), vol. 93, doi:doi:10.1016/j.jphotobiol.2008.06.010, pages 23 - 31, XP025479324 DOI: http://dx.doi.org/10.1016/j.jphotobiol.2008.06.010
		- I. NISHIDATE, Y. AIZU, H. MISHINA, "Estimation of melanin and hemoglobin in skin tissue using multiple regression analysis aided by Monte Carlo simulation", JOURNAL OF BIOMEDICAL OPTICS, (2004), vol. 9, doi:doi:10.1117/1.1756918, pages 700 - 10, XP002385533 DOI: http://dx.doi.org/10.1117/1.1756918
		- J. SANDBY-MOLLER, T. POULSEN, H.C. WULF, "Influence of epidermal thickness, pigmentation and redness on skin autofluorescence", PHOTOCHEM PHOTOBIOL, (2003), vol. 77, pages 616 - 620
		- "Reflectance and fluorescence spectroscopy of human skin in vivo", Y.P. SINICHKIN, N. KOLLIAS, G.I. ZONIOS, S.R. UTZ, V.V. TUCHIN, Handbook of optical biomedical diagnostics, SPIE PRESS, (2002), pages 725 - 785
		- G.N. STAMATAS, R.B. ESTANISLAO, M. SUERO, Z.S. RIVERA, J. LI, A. KHAIAT, N. KOLLIAS, "Facial skin fluorescence as a marker of the skin's response to chronic environmental insults and its dependence on age", BR J DERMATOL, (2006), vol. 154, pages 125 - 132
		- H. UENO, H. KOYAMA, S. TANAKA, S. FUKUMOTO, K. SHINOHARA, T. SHOJI, M. EMOTO, H. TAHARA, R. KAKIYA, T. TABATA, "Skin autofluorescence, a marker for advanced glycation end product accumulation, is associated with arterial stiffness in patients with end-stage renal disease", METABOLISM, (2008), vol. 57, doi:doi:10.1016/j.metabol.2008.05.016, pages 1452 - 1457, XP025425522 DOI: http://dx.doi.org/10.1016/j.metabol.2008.05.016
		- G. ZONIOS, A. DIMOU, "Modeling diffuse reflectance from semi- infinite turbid media: application to the study of skin optical properties", OPT EXPRESS, (2006), vol. 14, pages 8661 - 8674
		- G. ZONIOS, A. DIMOU, I. BASSUKAS, D. GALARIS, A. TSOLAKIDIS, E. KAXIRAS, "Melanin absorption spectroscopy: new method for noninvasive skin investigation and melanoma detection", J BIOMED OPT, (2008), vol. 13, page 14017
		- G. ZONIOS, A. DIMOU, "Melanin optical properties provide evidence for chemical and structural disorder in vivo", OPT EXPRESS, (2008), vol. 16, pages 8263 - 8268

The EPO accepts no responsibility for the accuracy of data originating from other authorities; in particular, it does not guarantee that it is complete, up to date or fit for specific purposes.

Legal notice
Terms of use
24.2.25; 35p