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Extract from the Register of European Patents

EP About this file: EP2567235

EP2567235 - METHOD FOR THE DIAGNOSIS OF EPITHELIAL CANCERS BY THE DETECTION OF EPICD POLYPEPTIDE [Right-click to bookmark this link]
StatusNo opposition filed within time limit
Status updated on  06.07.2018
Database last updated on 31.08.2024
FormerThe patent has been granted
Status updated on  28.07.2017
FormerGrant of patent is intended
Status updated on  13.03.2017
FormerExamination is in progress
Status updated on  04.03.2017
Most recent event   Tooltip10.07.2020Lapse of the patent in a contracting state
New state(s): AL
published on 12.08.2020  [2020/33]
Applicant(s)For all designated states
Walfish, Paul
68 Yorkville Avenue
Suite 402
Toronto, Ontario M5R 3V7 / CA
For all designated states
Ralhan, Ranju
385 Conley Street
Thornhill, Ontario L4J 6T2 / CA
[2013/11]
Inventor(s)01 / see applicant
...
 [2013/11]
Representative(s)Schiweck Weinzierl Koch Patentanwälte Partnerschaft mbB
Ganghoferstraße 68 B
80339 München / DE
[N/P]
Former [2017/35]Schiweck, Weinzierl & Koch Patentanwälte Partnerschaft mbB
Landsberger Straße 98
80339 München / DE
Former [2013/11]Schiweck, Weinzierl & Koch
European Patent Attorneys Landsberger Straße 98
80339 München / DE
Application number, filing date11777047.904.05.2011
[2017/35]
WO2011CA00511
Priority number, dateUS20100332358P07.05.2010         Original published format: US 332358 P
US20100330966P04.05.2010         Original published format: US 330966 P
[2013/11]
Filing languageEN
Procedural languageEN
PublicationType: A1 Application with search report
No.:WO2011137513
Date:10.11.2011
Language:EN
[2011/45]
Type: A1 Application with search report 
No.:EP2567235
Date:13.03.2013
Language:EN
The application published by WIPO in one of the EPO official languages on 10.11.2011 takes the place of the publication of the European patent application.
[2013/11]
Type: B1 Patent specification 
No.:EP2567235
Date:30.08.2017
Language:EN
[2017/35]
Search report(s)International search report - published on:CA10.11.2011
(Supplementary) European search report - dispatched on:EP27.08.2013
ClassificationIPC:G01N33/574, C12Q1/68
[2013/39]
CPC:
C12Q1/6886 (EP,US); G01N33/57407 (EP,US); C12Q2600/112 (EP,US);
C12Q2600/136 (EP,US); C12Q2600/158 (EP,US)
Former IPC [2013/11]G01N33/574
Designated contracting statesAL,   AT,   BE,   BG,   CH,   CY,   CZ,   DE,   DK,   EE,   ES,   FI,   FR,   GB,   GR,   HR,   HU,   IE,   IS,   IT,   LI,   LT,   LU,   LV,   MC,   MK,   MT,   NL,   NO,   PL,   PT,   RO,   RS,   SE,   SI,   SK,   SM,   TR [2013/11]
Extension statesBANot yet paid
MENot yet paid
TitleGerman:VERFAHREN ZUR DIAGNOSE VON EPITHELKARZINOMEN DURCH NACHWEIS EINES EPICD-POLYPEPTIDS[2013/11]
English:METHOD FOR THE DIAGNOSIS OF EPITHELIAL CANCERS BY THE DETECTION OF EPICD POLYPEPTIDE[2013/11]
French:PROCÉDÉ POUR LE DIAGNOSTIC DE CANCERS ÉPITHÉLIAUX PAR DÉTECTION DE POLYPEPTIDE EPICD[2013/11]
Entry into regional phase28.11.2012National basic fee paid 
28.11.2012Search fee paid 
28.11.2012Designation fee(s) paid 
28.11.2012Examination fee paid 
Examination procedure28.11.2012Examination requested  [2013/11]
20.03.2014Amendment by applicant (claims and/or description)
24.04.2014Despatch of a communication from the examining division (Time limit: M04)
01.09.2014Reply to a communication from the examining division
04.08.2015Despatch of a communication from the examining division (Time limit: M02)
30.09.2015Reply to a communication from the examining division
13.09.2016Cancellation of oral proceeding that was planned for 03.11.2016
26.10.2016Communication of intention to grant the patent
03.11.2016Date of oral proceedings (cancelled)
02.03.2017Disapproval of the communication of intention to grant the patent by the applicant or resumption of examination proceedings by the EPO
02.03.2017Fee for grant paid
02.03.2017Fee for publishing/printing paid
21.03.2017Communication of intention to grant the patent
20.07.2017Receipt of the translation of the claim(s)
Divisional application(s)The date of the Examining Division's first communication in respect of the earliest application for which a communication has been issued is  24.04.2014
Opposition(s)31.05.2018No opposition filed within time limit [2018/32]
Fees paidRenewal fee
28.05.2013Renewal fee patent year 03
27.05.2014Renewal fee patent year 04
27.05.2015Renewal fee patent year 05
27.05.2016Renewal fee patent year 06
30.05.2017Renewal fee patent year 07
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Lapses during opposition  TooltipHU04.05.2011
AL30.08.2017
AT30.08.2017
CY30.08.2017
CZ30.08.2017
DK30.08.2017
EE30.08.2017
ES30.08.2017
FI30.08.2017
HR30.08.2017
IT30.08.2017
LT30.08.2017
LV30.08.2017
MC30.08.2017
MK30.08.2017
NL30.08.2017
PL30.08.2017
PT30.08.2017
RO30.08.2017
RS30.08.2017
SE30.08.2017
SI30.08.2017
SK30.08.2017
SM30.08.2017
TR30.08.2017
BG30.11.2017
NO30.11.2017
GR01.12.2017
IS30.12.2017
IE04.05.2018
LU04.05.2018
MT04.05.2018
[2020/33]
Former [2020/31]HU04.05.2011
AT30.08.2017
CY30.08.2017
CZ30.08.2017
DK30.08.2017
EE30.08.2017
ES30.08.2017
FI30.08.2017
HR30.08.2017
IT30.08.2017
LT30.08.2017
LV30.08.2017
MC30.08.2017
MK30.08.2017
NL30.08.2017
PL30.08.2017
PT30.08.2017
RO30.08.2017
RS30.08.2017
SE30.08.2017
SI30.08.2017
SK30.08.2017
SM30.08.2017
TR30.08.2017
BG30.11.2017
NO30.11.2017
GR01.12.2017
IS30.12.2017
IE04.05.2018
LU04.05.2018
MT04.05.2018
Former [2020/27]HU04.05.2011
AT30.08.2017
CZ30.08.2017
DK30.08.2017
EE30.08.2017
ES30.08.2017
FI30.08.2017
HR30.08.2017
IT30.08.2017
LT30.08.2017
LV30.08.2017
MC30.08.2017
NL30.08.2017
PL30.08.2017
PT30.08.2017
RO30.08.2017
RS30.08.2017
SE30.08.2017
SI30.08.2017
SK30.08.2017
SM30.08.2017
TR30.08.2017
BG30.11.2017
NO30.11.2017
GR01.12.2017
IS30.12.2017
IE04.05.2018
LU04.05.2018
MT04.05.2018
Former [2020/16]AT30.08.2017
CZ30.08.2017
DK30.08.2017
EE30.08.2017
ES30.08.2017
FI30.08.2017
HR30.08.2017
IT30.08.2017
LT30.08.2017
LV30.08.2017
MC30.08.2017
NL30.08.2017
PL30.08.2017
RO30.08.2017
RS30.08.2017
SE30.08.2017
SI30.08.2017
SK30.08.2017
SM30.08.2017
TR30.08.2017
BG30.11.2017
NO30.11.2017
GR01.12.2017
IS30.12.2017
IE04.05.2018
LU04.05.2018
MT04.05.2018
Former [2020/08]AT30.08.2017
CZ30.08.2017
DK30.08.2017
EE30.08.2017
ES30.08.2017
FI30.08.2017
HR30.08.2017
IT30.08.2017
LT30.08.2017
LV30.08.2017
MC30.08.2017
NL30.08.2017
PL30.08.2017
RO30.08.2017
RS30.08.2017
SE30.08.2017
SI30.08.2017
SK30.08.2017
SM30.08.2017
BG30.11.2017
NO30.11.2017
GR01.12.2017
IS30.12.2017
IE04.05.2018
LU04.05.2018
MT04.05.2018
Former [2019/19]AT30.08.2017
CZ30.08.2017
DK30.08.2017
EE30.08.2017
ES30.08.2017
FI30.08.2017
HR30.08.2017
IT30.08.2017
LT30.08.2017
LV30.08.2017
MC30.08.2017
NL30.08.2017
PL30.08.2017
RO30.08.2017
RS30.08.2017
SE30.08.2017
SI30.08.2017
SK30.08.2017
SM30.08.2017
BG30.11.2017
NO30.11.2017
GR01.12.2017
IS30.12.2017
IE04.05.2018
LU04.05.2018
Former [2019/17]AT30.08.2017
CZ30.08.2017
DK30.08.2017
EE30.08.2017
ES30.08.2017
FI30.08.2017
HR30.08.2017
IT30.08.2017
LT30.08.2017
LV30.08.2017
MC30.08.2017
NL30.08.2017
PL30.08.2017
RO30.08.2017
RS30.08.2017
SE30.08.2017
SI30.08.2017
SK30.08.2017
SM30.08.2017
BG30.11.2017
NO30.11.2017
GR01.12.2017
IS30.12.2017
LU04.05.2018
Former [2019/06]AT30.08.2017
CZ30.08.2017
DK30.08.2017
EE30.08.2017
ES30.08.2017
FI30.08.2017
HR30.08.2017
IT30.08.2017
LT30.08.2017
LV30.08.2017
MC30.08.2017
NL30.08.2017
PL30.08.2017
RO30.08.2017
RS30.08.2017
SE30.08.2017
SI30.08.2017
SK30.08.2017
SM30.08.2017
BG30.11.2017
NO30.11.2017
GR01.12.2017
IS30.12.2017
Former [2018/39]AT30.08.2017
CZ30.08.2017
DK30.08.2017
EE30.08.2017
ES30.08.2017
FI30.08.2017
HR30.08.2017
IT30.08.2017
LT30.08.2017
LV30.08.2017
NL30.08.2017
PL30.08.2017
RO30.08.2017
RS30.08.2017
SE30.08.2017
SI30.08.2017
SK30.08.2017
SM30.08.2017
BG30.11.2017
NO30.11.2017
GR01.12.2017
IS30.12.2017
Former [2018/24]AT30.08.2017
CZ30.08.2017
DK30.08.2017
EE30.08.2017
ES30.08.2017
FI30.08.2017
HR30.08.2017
IT30.08.2017
LT30.08.2017
LV30.08.2017
NL30.08.2017
PL30.08.2017
RO30.08.2017
RS30.08.2017
SE30.08.2017
SK30.08.2017
SM30.08.2017
BG30.11.2017
NO30.11.2017
GR01.12.2017
IS30.12.2017
Former [2018/23]AT30.08.2017
CZ30.08.2017
DK30.08.2017
EE30.08.2017
ES30.08.2017
FI30.08.2017
HR30.08.2017
LT30.08.2017
LV30.08.2017
NL30.08.2017
PL30.08.2017
RO30.08.2017
RS30.08.2017
SE30.08.2017
SK30.08.2017
BG30.11.2017
NO30.11.2017
GR01.12.2017
IS30.12.2017
Former [2018/21]AT30.08.2017
CZ30.08.2017
DK30.08.2017
ES30.08.2017
FI30.08.2017
HR30.08.2017
LT30.08.2017
LV30.08.2017
NL30.08.2017
RS30.08.2017
SE30.08.2017
BG30.11.2017
NO30.11.2017
GR01.12.2017
IS30.12.2017
Former [2018/15]AT30.08.2017
ES30.08.2017
FI30.08.2017
HR30.08.2017
LT30.08.2017
LV30.08.2017
NL30.08.2017
RS30.08.2017
SE30.08.2017
BG30.11.2017
NO30.11.2017
GR01.12.2017
IS30.12.2017
Former [2018/12]AT30.08.2017
ES30.08.2017
FI30.08.2017
HR30.08.2017
LT30.08.2017
LV30.08.2017
RS30.08.2017
SE30.08.2017
BG30.11.2017
NO30.11.2017
GR01.12.2017
IS30.12.2017
Former [2018/11]AT30.08.2017
ES30.08.2017
FI30.08.2017
HR30.08.2017
LT30.08.2017
RS30.08.2017
SE30.08.2017
BG30.11.2017
NO30.11.2017
GR01.12.2017
IS30.12.2017
Former [2018/10]AT30.08.2017
FI30.08.2017
HR30.08.2017
LT30.08.2017
RS30.08.2017
SE30.08.2017
NO30.11.2017
Former [2018/09]FI30.08.2017
LT30.08.2017
SE30.08.2017
NO30.11.2017
Former [2018/08]FI30.08.2017
LT30.08.2017
NO30.11.2017
Former [2018/07]LT30.08.2017
NO30.11.2017
Documents cited:Search[XY]WO2004093808  (MAXYGEN INC [US], et al) [X] 15 * paragraphs [0057] , [0263] - [0278] - [ 432] , [0433] , [0497]; claim 134; sequence 46 * [Y] 1-14;
 [E]WO2012153186  (KALGENE PHARMACEUTICALS INC [CA], et al) [E] 1-15 * paragraphs [0011] , [0052] , [0053]; claims 15-21 *;
 [XY]  - DOROTHEA MAETZEL ET AL, "Nuclear signalling by tumour-associated antigen EpCAM", NATURE CELL BIOLOGY, (20090201), vol. 11, no. 2, doi:10.1038/ncb1824, ISSN 1465-7392, pages 162 - 171, XP055011161 [X] 1-15 * page 169 - page 170; figure 1 * [Y] 1-14

DOI:   http://dx.doi.org/10.1038/ncb1824
International search[X]  - MAETZEL ET AL., "Nuclear signalling by tumour-associated antigen EpCAM", NATURE CELL BIOLOGY, (2009), vol. 11, no. 2, pages 162 - 171, XP055011161

DOI:   http://dx.doi.org/10.1038/ncb1824
 [XP]  - RALHAN ET AL., "EpCAM nuclear localization identifies aggressive thyroid cancer and is a marker for poor prognosis", BMC CANCER, (20100625), vol. 10, pages 331 - 341, XP021075153

DOI:   http://dx.doi.org/10.1186/1471-2407-10-331
 [XP]  - RALHAN ET AL., "Nuclear and cytoplasmic accumulation of Ep-ICD is frequently detected in human epithelial cancers", PLOS ONE, (201011), vol. 5, no. 11, pages E14130-1 - E14130-15, XP055068803

DOI:   http://dx.doi.org/10.1371/journal.pone.0014130
 [A]  - STOECKLEIN ET AL., "Ep-CAM expression in squamous cell carcinoma of the esophagus: a potential therapeutic target and prognostic marker", BMC CANCER, (2006), vol. 6, XP021016158

DOI:   http://dx.doi.org/10.1186/1471-2407-6-165
by applicantWO2004093808
 US5474796
 WO9525116
 WO9535505
 US5605662
 US5312922
 US5208020
 US7557190
 US7459538
 US2005163785
 US2007122406
 US2007196366
    - MAETZEL ET AL., NAT CELL BIOL., (2009), vol. 11, pages 162 - 171
    - LITVINOV ET AL., J CELL BIOL., (1997), vol. 139, pages 1337 - 1348
    - MUNZ ET AL., CANCER RES., (2009), vol. 69, pages 5627 - 5629
    - BALZAR ET AL., MOL CELL BIOL., (2001), vol. 21, no. 7, pages 2570 - 80
    - BAEUERIE PA; 0 GIRES, BRITISH JOURNAL OF CANCER, (2007), vol. 96, pages 417 - 423
    - DEVEREUX J. ET AL., NUCLEIC ACIDS RESEARCH, (1984), vol. 12, no. 1, page 387
    - ATSCHUL, S.F. ET AL., J. MOLEC. BIOL., (1990), vol. 215, pages 403 - 410
    - ALTSCHUL, S. ET AL., J. MOL. BIOL., (1990), vol. 215, pages 403 - 410
    - Current Protocols in Molecular Biology, JOHN WILEY & SONS, (1989), pages 6.3.1 - 6.3.6
    - KLUG ET AL., MOL. BIOL. REPORTS, (1994), vol. 20, pages 97 - 107
    - WALLIS ET AL., CHEM. BIOL., (1995), vol. 2, pages 543 - 552
    - ELLINGTON, CURR. BIOL., (1994), vol. 4, pages 427 - 429
    - LATO ET AL., CHEM. BIOL., (1995), vol. 2, pages 291 - 303
    - CONRAD ET AL., MOL. DIV., (1995), vol. 1, pages 69 - 78
    - UPHOFF ET AL., CURR. OPIN. STRUCT. BIOL., (1996), vol. 6, pages 281 - 287
    - KOHLER ET AL., NATURE, (1975), vol. 256, pages 495 - 497
    - KOZBOR ET AL., J. IMMUNOL METHODS, (1985), vol. 81, pages 31 - 42
    - COTE ET AL., PROC NATL ACAD SCI, (1983), vol. 80, pages 2026 - 2030
    - COLE ET AL., MOL CELL BIOL, (1984), vol. 62, pages 109 - 120
    - HUSE ET AL., SCIENCE, (1989), vol. 246, pages 1275 - 1281
    - SCHENA ET AL., PROC. NATL. ACAD. SCI., (1996), vol. 93, pages 10614 - 10619
    - HELLER, R. A. ET AL., PROC. NATL. ACAD. SCI., (1997), vol. 94, pages 2150 - 2155
    - PATERSON ET AL., INT. J. CAN., (1986), vol. 37, page 659
    - BURCHELL ET AL., INT. J. CAN., (1984), vol. 34, page 763
    - CHRISTOPOULOS TK; DIAMANDIS EP, ANAL. CHEM., (1992), vol. 64, pages 342 - 346
    - MCDONALD ET AL., DRUG DESIGN, DEVELOPMENT AND THERAPY, (2008), vol. 2, pages 105 - 114
    - MYKLEBUST ET AL., CANCER RES., (19930815), vol. 53, no. 16, pages 3784 - 8
    - RALHAN ET AL., J PROTEOME RES., (200901), vol. 8, no. 1, pages 300 - 9
The EPO accepts no responsibility for the accuracy of data originating from other authorities; in particular, it does not guarantee that it is complete, up to date or fit for specific purposes.