EP2567235 - METHOD FOR THE DIAGNOSIS OF EPITHELIAL CANCERS BY THE DETECTION OF EPICD POLYPEPTIDE [Right-click to bookmark this link] | Status | No opposition filed within time limit Status updated on 06.07.2018 Database last updated on 31.08.2024 | |
Former | The patent has been granted Status updated on 28.07.2017 | ||
Former | Grant of patent is intended Status updated on 13.03.2017 | ||
Former | Examination is in progress Status updated on 04.03.2017 | Most recent event Tooltip | 10.07.2020 | Lapse of the patent in a contracting state New state(s): AL | published on 12.08.2020 [2020/33] | Applicant(s) | For all designated states Walfish, Paul 68 Yorkville Avenue Suite 402 Toronto, Ontario M5R 3V7 / CA | For all designated states Ralhan, Ranju 385 Conley Street Thornhill, Ontario L4J 6T2 / CA | [2013/11] | Inventor(s) | 01 /
see applicant ... | [2013/11] | Representative(s) | Schiweck Weinzierl Koch Patentanwälte Partnerschaft mbB Ganghoferstraße 68 B 80339 München / DE | [N/P] |
Former [2017/35] | Schiweck, Weinzierl & Koch Patentanwälte Partnerschaft mbB Landsberger Straße 98 80339 München / DE | ||
Former [2013/11] | Schiweck, Weinzierl & Koch European Patent Attorneys Landsberger Straße 98 80339 München / DE | Application number, filing date | 11777047.9 | 04.05.2011 | [2017/35] | WO2011CA00511 | Priority number, date | US20100332358P | 07.05.2010 Original published format: US 332358 P | US20100330966P | 04.05.2010 Original published format: US 330966 P | [2013/11] | Filing language | EN | Procedural language | EN | Publication | Type: | A1 Application with search report | No.: | WO2011137513 | Date: | 10.11.2011 | Language: | EN | [2011/45] | Type: | A1 Application with search report | No.: | EP2567235 | Date: | 13.03.2013 | Language: | EN | The application published by WIPO in one of the EPO official languages on 10.11.2011 takes the place of the publication of the European patent application. | [2013/11] | Type: | B1 Patent specification | No.: | EP2567235 | Date: | 30.08.2017 | Language: | EN | [2017/35] | Search report(s) | International search report - published on: | CA | 10.11.2011 | (Supplementary) European search report - dispatched on: | EP | 27.08.2013 | Classification | IPC: | G01N33/574, C12Q1/68 | [2013/39] | CPC: |
C12Q1/6886 (EP,US);
G01N33/57407 (EP,US);
C12Q2600/112 (EP,US);
C12Q2600/136 (EP,US);
C12Q2600/158 (EP,US)
|
Former IPC [2013/11] | G01N33/574 | Designated contracting states | AL, AT, BE, BG, CH, CY, CZ, DE, DK, EE, ES, FI, FR, GB, GR, HR, HU, IE, IS, IT, LI, LT, LU, LV, MC, MK, MT, NL, NO, PL, PT, RO, RS, SE, SI, SK, SM, TR [2013/11] | Extension states | BA | Not yet paid | ME | Not yet paid | Title | German: | VERFAHREN ZUR DIAGNOSE VON EPITHELKARZINOMEN DURCH NACHWEIS EINES EPICD-POLYPEPTIDS | [2013/11] | English: | METHOD FOR THE DIAGNOSIS OF EPITHELIAL CANCERS BY THE DETECTION OF EPICD POLYPEPTIDE | [2013/11] | French: | PROCÉDÉ POUR LE DIAGNOSTIC DE CANCERS ÉPITHÉLIAUX PAR DÉTECTION DE POLYPEPTIDE EPICD | [2013/11] | Entry into regional phase | 28.11.2012 | National basic fee paid | 28.11.2012 | Search fee paid | 28.11.2012 | Designation fee(s) paid | 28.11.2012 | Examination fee paid | Examination procedure | 28.11.2012 | Examination requested [2013/11] | 20.03.2014 | Amendment by applicant (claims and/or description) | 24.04.2014 | Despatch of a communication from the examining division (Time limit: M04) | 01.09.2014 | Reply to a communication from the examining division | 04.08.2015 | Despatch of a communication from the examining division (Time limit: M02) | 30.09.2015 | Reply to a communication from the examining division | 13.09.2016 | Cancellation of oral proceeding that was planned for 03.11.2016 | 26.10.2016 | Communication of intention to grant the patent | 03.11.2016 | Date of oral proceedings (cancelled) | 02.03.2017 | Disapproval of the communication of intention to grant the patent by the applicant or resumption of examination proceedings by the EPO | 02.03.2017 | Fee for grant paid | 02.03.2017 | Fee for publishing/printing paid | 21.03.2017 | Communication of intention to grant the patent | 20.07.2017 | Receipt of the translation of the claim(s) | Divisional application(s) | The date of the Examining Division's first communication in respect of the earliest application for which a communication has been issued is 24.04.2014 | Opposition(s) | 31.05.2018 | No opposition filed within time limit [2018/32] | Fees paid | Renewal fee | 28.05.2013 | Renewal fee patent year 03 | 27.05.2014 | Renewal fee patent year 04 | 27.05.2015 | Renewal fee patent year 05 | 27.05.2016 | Renewal fee patent year 06 | 30.05.2017 | Renewal fee patent year 07 |
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Responsibility for the accuracy, completeness or quality of the data displayed under the link provided lies entirely with the Unified Patent Court. | Lapses during opposition Tooltip | HU | 04.05.2011 | AL | 30.08.2017 | AT | 30.08.2017 | CY | 30.08.2017 | CZ | 30.08.2017 | DK | 30.08.2017 | EE | 30.08.2017 | ES | 30.08.2017 | FI | 30.08.2017 | HR | 30.08.2017 | IT | 30.08.2017 | LT | 30.08.2017 | LV | 30.08.2017 | MC | 30.08.2017 | MK | 30.08.2017 | NL | 30.08.2017 | PL | 30.08.2017 | PT | 30.08.2017 | RO | 30.08.2017 | RS | 30.08.2017 | SE | 30.08.2017 | SI | 30.08.2017 | SK | 30.08.2017 | SM | 30.08.2017 | TR | 30.08.2017 | BG | 30.11.2017 | NO | 30.11.2017 | GR | 01.12.2017 | IS | 30.12.2017 | IE | 04.05.2018 | LU | 04.05.2018 | MT | 04.05.2018 | [2020/33] |
Former [2020/31] | HU | 04.05.2011 | |
AT | 30.08.2017 | ||
CY | 30.08.2017 | ||
CZ | 30.08.2017 | ||
DK | 30.08.2017 | ||
EE | 30.08.2017 | ||
ES | 30.08.2017 | ||
FI | 30.08.2017 | ||
HR | 30.08.2017 | ||
IT | 30.08.2017 | ||
LT | 30.08.2017 | ||
LV | 30.08.2017 | ||
MC | 30.08.2017 | ||
MK | 30.08.2017 | ||
NL | 30.08.2017 | ||
PL | 30.08.2017 | ||
PT | 30.08.2017 | ||
RO | 30.08.2017 | ||
RS | 30.08.2017 | ||
SE | 30.08.2017 | ||
SI | 30.08.2017 | ||
SK | 30.08.2017 | ||
SM | 30.08.2017 | ||
TR | 30.08.2017 | ||
BG | 30.11.2017 | ||
NO | 30.11.2017 | ||
GR | 01.12.2017 | ||
IS | 30.12.2017 | ||
IE | 04.05.2018 | ||
LU | 04.05.2018 | ||
MT | 04.05.2018 | ||
Former [2020/27] | HU | 04.05.2011 | |
AT | 30.08.2017 | ||
CZ | 30.08.2017 | ||
DK | 30.08.2017 | ||
EE | 30.08.2017 | ||
ES | 30.08.2017 | ||
FI | 30.08.2017 | ||
HR | 30.08.2017 | ||
IT | 30.08.2017 | ||
LT | 30.08.2017 | ||
LV | 30.08.2017 | ||
MC | 30.08.2017 | ||
NL | 30.08.2017 | ||
PL | 30.08.2017 | ||
PT | 30.08.2017 | ||
RO | 30.08.2017 | ||
RS | 30.08.2017 | ||
SE | 30.08.2017 | ||
SI | 30.08.2017 | ||
SK | 30.08.2017 | ||
SM | 30.08.2017 | ||
TR | 30.08.2017 | ||
BG | 30.11.2017 | ||
NO | 30.11.2017 | ||
GR | 01.12.2017 | ||
IS | 30.12.2017 | ||
IE | 04.05.2018 | ||
LU | 04.05.2018 | ||
MT | 04.05.2018 | ||
Former [2020/16] | AT | 30.08.2017 | |
CZ | 30.08.2017 | ||
DK | 30.08.2017 | ||
EE | 30.08.2017 | ||
ES | 30.08.2017 | ||
FI | 30.08.2017 | ||
HR | 30.08.2017 | ||
IT | 30.08.2017 | ||
LT | 30.08.2017 | ||
LV | 30.08.2017 | ||
MC | 30.08.2017 | ||
NL | 30.08.2017 | ||
PL | 30.08.2017 | ||
RO | 30.08.2017 | ||
RS | 30.08.2017 | ||
SE | 30.08.2017 | ||
SI | 30.08.2017 | ||
SK | 30.08.2017 | ||
SM | 30.08.2017 | ||
TR | 30.08.2017 | ||
BG | 30.11.2017 | ||
NO | 30.11.2017 | ||
GR | 01.12.2017 | ||
IS | 30.12.2017 | ||
IE | 04.05.2018 | ||
LU | 04.05.2018 | ||
MT | 04.05.2018 | ||
Former [2020/08] | AT | 30.08.2017 | |
CZ | 30.08.2017 | ||
DK | 30.08.2017 | ||
EE | 30.08.2017 | ||
ES | 30.08.2017 | ||
FI | 30.08.2017 | ||
HR | 30.08.2017 | ||
IT | 30.08.2017 | ||
LT | 30.08.2017 | ||
LV | 30.08.2017 | ||
MC | 30.08.2017 | ||
NL | 30.08.2017 | ||
PL | 30.08.2017 | ||
RO | 30.08.2017 | ||
RS | 30.08.2017 | ||
SE | 30.08.2017 | ||
SI | 30.08.2017 | ||
SK | 30.08.2017 | ||
SM | 30.08.2017 | ||
BG | 30.11.2017 | ||
NO | 30.11.2017 | ||
GR | 01.12.2017 | ||
IS | 30.12.2017 | ||
IE | 04.05.2018 | ||
LU | 04.05.2018 | ||
MT | 04.05.2018 | ||
Former [2019/19] | AT | 30.08.2017 | |
CZ | 30.08.2017 | ||
DK | 30.08.2017 | ||
EE | 30.08.2017 | ||
ES | 30.08.2017 | ||
FI | 30.08.2017 | ||
HR | 30.08.2017 | ||
IT | 30.08.2017 | ||
LT | 30.08.2017 | ||
LV | 30.08.2017 | ||
MC | 30.08.2017 | ||
NL | 30.08.2017 | ||
PL | 30.08.2017 | ||
RO | 30.08.2017 | ||
RS | 30.08.2017 | ||
SE | 30.08.2017 | ||
SI | 30.08.2017 | ||
SK | 30.08.2017 | ||
SM | 30.08.2017 | ||
BG | 30.11.2017 | ||
NO | 30.11.2017 | ||
GR | 01.12.2017 | ||
IS | 30.12.2017 | ||
IE | 04.05.2018 | ||
LU | 04.05.2018 | ||
Former [2019/17] | AT | 30.08.2017 | |
CZ | 30.08.2017 | ||
DK | 30.08.2017 | ||
EE | 30.08.2017 | ||
ES | 30.08.2017 | ||
FI | 30.08.2017 | ||
HR | 30.08.2017 | ||
IT | 30.08.2017 | ||
LT | 30.08.2017 | ||
LV | 30.08.2017 | ||
MC | 30.08.2017 | ||
NL | 30.08.2017 | ||
PL | 30.08.2017 | ||
RO | 30.08.2017 | ||
RS | 30.08.2017 | ||
SE | 30.08.2017 | ||
SI | 30.08.2017 | ||
SK | 30.08.2017 | ||
SM | 30.08.2017 | ||
BG | 30.11.2017 | ||
NO | 30.11.2017 | ||
GR | 01.12.2017 | ||
IS | 30.12.2017 | ||
LU | 04.05.2018 | ||
Former [2019/06] | AT | 30.08.2017 | |
CZ | 30.08.2017 | ||
DK | 30.08.2017 | ||
EE | 30.08.2017 | ||
ES | 30.08.2017 | ||
FI | 30.08.2017 | ||
HR | 30.08.2017 | ||
IT | 30.08.2017 | ||
LT | 30.08.2017 | ||
LV | 30.08.2017 | ||
MC | 30.08.2017 | ||
NL | 30.08.2017 | ||
PL | 30.08.2017 | ||
RO | 30.08.2017 | ||
RS | 30.08.2017 | ||
SE | 30.08.2017 | ||
SI | 30.08.2017 | ||
SK | 30.08.2017 | ||
SM | 30.08.2017 | ||
BG | 30.11.2017 | ||
NO | 30.11.2017 | ||
GR | 01.12.2017 | ||
IS | 30.12.2017 | ||
Former [2018/39] | AT | 30.08.2017 | |
CZ | 30.08.2017 | ||
DK | 30.08.2017 | ||
EE | 30.08.2017 | ||
ES | 30.08.2017 | ||
FI | 30.08.2017 | ||
HR | 30.08.2017 | ||
IT | 30.08.2017 | ||
LT | 30.08.2017 | ||
LV | 30.08.2017 | ||
NL | 30.08.2017 | ||
PL | 30.08.2017 | ||
RO | 30.08.2017 | ||
RS | 30.08.2017 | ||
SE | 30.08.2017 | ||
SI | 30.08.2017 | ||
SK | 30.08.2017 | ||
SM | 30.08.2017 | ||
BG | 30.11.2017 | ||
NO | 30.11.2017 | ||
GR | 01.12.2017 | ||
IS | 30.12.2017 | ||
Former [2018/24] | AT | 30.08.2017 | |
CZ | 30.08.2017 | ||
DK | 30.08.2017 | ||
EE | 30.08.2017 | ||
ES | 30.08.2017 | ||
FI | 30.08.2017 | ||
HR | 30.08.2017 | ||
IT | 30.08.2017 | ||
LT | 30.08.2017 | ||
LV | 30.08.2017 | ||
NL | 30.08.2017 | ||
PL | 30.08.2017 | ||
RO | 30.08.2017 | ||
RS | 30.08.2017 | ||
SE | 30.08.2017 | ||
SK | 30.08.2017 | ||
SM | 30.08.2017 | ||
BG | 30.11.2017 | ||
NO | 30.11.2017 | ||
GR | 01.12.2017 | ||
IS | 30.12.2017 | ||
Former [2018/23] | AT | 30.08.2017 | |
CZ | 30.08.2017 | ||
DK | 30.08.2017 | ||
EE | 30.08.2017 | ||
ES | 30.08.2017 | ||
FI | 30.08.2017 | ||
HR | 30.08.2017 | ||
LT | 30.08.2017 | ||
LV | 30.08.2017 | ||
NL | 30.08.2017 | ||
PL | 30.08.2017 | ||
RO | 30.08.2017 | ||
RS | 30.08.2017 | ||
SE | 30.08.2017 | ||
SK | 30.08.2017 | ||
BG | 30.11.2017 | ||
NO | 30.11.2017 | ||
GR | 01.12.2017 | ||
IS | 30.12.2017 | ||
Former [2018/21] | AT | 30.08.2017 | |
CZ | 30.08.2017 | ||
DK | 30.08.2017 | ||
ES | 30.08.2017 | ||
FI | 30.08.2017 | ||
HR | 30.08.2017 | ||
LT | 30.08.2017 | ||
LV | 30.08.2017 | ||
NL | 30.08.2017 | ||
RS | 30.08.2017 | ||
SE | 30.08.2017 | ||
BG | 30.11.2017 | ||
NO | 30.11.2017 | ||
GR | 01.12.2017 | ||
IS | 30.12.2017 | ||
Former [2018/15] | AT | 30.08.2017 | |
ES | 30.08.2017 | ||
FI | 30.08.2017 | ||
HR | 30.08.2017 | ||
LT | 30.08.2017 | ||
LV | 30.08.2017 | ||
NL | 30.08.2017 | ||
RS | 30.08.2017 | ||
SE | 30.08.2017 | ||
BG | 30.11.2017 | ||
NO | 30.11.2017 | ||
GR | 01.12.2017 | ||
IS | 30.12.2017 | ||
Former [2018/12] | AT | 30.08.2017 | |
ES | 30.08.2017 | ||
FI | 30.08.2017 | ||
HR | 30.08.2017 | ||
LT | 30.08.2017 | ||
LV | 30.08.2017 | ||
RS | 30.08.2017 | ||
SE | 30.08.2017 | ||
BG | 30.11.2017 | ||
NO | 30.11.2017 | ||
GR | 01.12.2017 | ||
IS | 30.12.2017 | ||
Former [2018/11] | AT | 30.08.2017 | |
ES | 30.08.2017 | ||
FI | 30.08.2017 | ||
HR | 30.08.2017 | ||
LT | 30.08.2017 | ||
RS | 30.08.2017 | ||
SE | 30.08.2017 | ||
BG | 30.11.2017 | ||
NO | 30.11.2017 | ||
GR | 01.12.2017 | ||
IS | 30.12.2017 | ||
Former [2018/10] | AT | 30.08.2017 | |
FI | 30.08.2017 | ||
HR | 30.08.2017 | ||
LT | 30.08.2017 | ||
RS | 30.08.2017 | ||
SE | 30.08.2017 | ||
NO | 30.11.2017 | ||
Former [2018/09] | FI | 30.08.2017 | |
LT | 30.08.2017 | ||
SE | 30.08.2017 | ||
NO | 30.11.2017 | ||
Former [2018/08] | FI | 30.08.2017 | |
LT | 30.08.2017 | ||
NO | 30.11.2017 | ||
Former [2018/07] | LT | 30.08.2017 | |
NO | 30.11.2017 | Documents cited: | Search | [XY]WO2004093808 (MAXYGEN INC [US], et al) [X] 15 * paragraphs [0057] , [0263] - [0278] - [ 432] , [0433] , [0497]; claim 134; sequence 46 * [Y] 1-14; | [E]WO2012153186 (KALGENE PHARMACEUTICALS INC [CA], et al) [E] 1-15 * paragraphs [0011] , [0052] , [0053]; claims 15-21 *; | [XY] - DOROTHEA MAETZEL ET AL, "Nuclear signalling by tumour-associated antigen EpCAM", NATURE CELL BIOLOGY, (20090201), vol. 11, no. 2, doi:10.1038/ncb1824, ISSN 1465-7392, pages 162 - 171, XP055011161 [X] 1-15 * page 169 - page 170; figure 1 * [Y] 1-14 DOI: http://dx.doi.org/10.1038/ncb1824 | International search | [X] - MAETZEL ET AL., "Nuclear signalling by tumour-associated antigen EpCAM", NATURE CELL BIOLOGY, (2009), vol. 11, no. 2, pages 162 - 171, XP055011161 DOI: http://dx.doi.org/10.1038/ncb1824 | [XP] - RALHAN ET AL., "EpCAM nuclear localization identifies aggressive thyroid cancer and is a marker for poor prognosis", BMC CANCER, (20100625), vol. 10, pages 331 - 341, XP021075153 DOI: http://dx.doi.org/10.1186/1471-2407-10-331 | [XP] - RALHAN ET AL., "Nuclear and cytoplasmic accumulation of Ep-ICD is frequently detected in human epithelial cancers", PLOS ONE, (201011), vol. 5, no. 11, pages E14130-1 - E14130-15, XP055068803 DOI: http://dx.doi.org/10.1371/journal.pone.0014130 | [A] - STOECKLEIN ET AL., "Ep-CAM expression in squamous cell carcinoma of the esophagus: a potential therapeutic target and prognostic marker", BMC CANCER, (2006), vol. 6, XP021016158 DOI: http://dx.doi.org/10.1186/1471-2407-6-165 | by applicant | WO2004093808 | US5474796 | WO9525116 | WO9535505 | US5605662 | US5312922 | US5208020 | US7557190 | US7459538 | US2005163785 | US2007122406 | US2007196366 | - MAETZEL ET AL., NAT CELL BIOL., (2009), vol. 11, pages 162 - 171 | - LITVINOV ET AL., J CELL BIOL., (1997), vol. 139, pages 1337 - 1348 | - MUNZ ET AL., CANCER RES., (2009), vol. 69, pages 5627 - 5629 | - BALZAR ET AL., MOL CELL BIOL., (2001), vol. 21, no. 7, pages 2570 - 80 | - BAEUERIE PA; 0 GIRES, BRITISH JOURNAL OF CANCER, (2007), vol. 96, pages 417 - 423 | - DEVEREUX J. ET AL., NUCLEIC ACIDS RESEARCH, (1984), vol. 12, no. 1, page 387 | - ATSCHUL, S.F. ET AL., J. MOLEC. BIOL., (1990), vol. 215, pages 403 - 410 | - ALTSCHUL, S. ET AL., J. MOL. BIOL., (1990), vol. 215, pages 403 - 410 | - Current Protocols in Molecular Biology, JOHN WILEY & SONS, (1989), pages 6.3.1 - 6.3.6 | - KLUG ET AL., MOL. BIOL. REPORTS, (1994), vol. 20, pages 97 - 107 | - WALLIS ET AL., CHEM. BIOL., (1995), vol. 2, pages 543 - 552 | - ELLINGTON, CURR. BIOL., (1994), vol. 4, pages 427 - 429 | - LATO ET AL., CHEM. BIOL., (1995), vol. 2, pages 291 - 303 | - CONRAD ET AL., MOL. DIV., (1995), vol. 1, pages 69 - 78 | - UPHOFF ET AL., CURR. OPIN. STRUCT. BIOL., (1996), vol. 6, pages 281 - 287 | - KOHLER ET AL., NATURE, (1975), vol. 256, pages 495 - 497 | - KOZBOR ET AL., J. IMMUNOL METHODS, (1985), vol. 81, pages 31 - 42 | - COTE ET AL., PROC NATL ACAD SCI, (1983), vol. 80, pages 2026 - 2030 | - COLE ET AL., MOL CELL BIOL, (1984), vol. 62, pages 109 - 120 | - HUSE ET AL., SCIENCE, (1989), vol. 246, pages 1275 - 1281 | - SCHENA ET AL., PROC. NATL. ACAD. SCI., (1996), vol. 93, pages 10614 - 10619 | - HELLER, R. A. ET AL., PROC. NATL. ACAD. SCI., (1997), vol. 94, pages 2150 - 2155 | - PATERSON ET AL., INT. J. CAN., (1986), vol. 37, page 659 | - BURCHELL ET AL., INT. J. CAN., (1984), vol. 34, page 763 | - CHRISTOPOULOS TK; DIAMANDIS EP, ANAL. CHEM., (1992), vol. 64, pages 342 - 346 | - MCDONALD ET AL., DRUG DESIGN, DEVELOPMENT AND THERAPY, (2008), vol. 2, pages 105 - 114 | - MYKLEBUST ET AL., CANCER RES., (19930815), vol. 53, no. 16, pages 3784 - 8 | - RALHAN ET AL., J PROTEOME RES., (200901), vol. 8, no. 1, pages 300 - 9 |