EP2640748 - LUTEINIZING-HORMONE LIGAND AND LIGAND-GONADOTROPHIN COMPLEX [Right-click to bookmark this link] | Status | No opposition filed within time limit Status updated on 12.01.2018 Database last updated on 06.07.2024 | |
Former | The patent has been granted Status updated on 03.02.2017 | ||
Former | Grant of patent is intended Status updated on 25.01.2017 | Most recent event Tooltip | 17.07.2020 | Lapse of the patent in a contracting state New state(s): AL | published on 19.08.2020 [2020/34] | Applicant(s) | For all designated states Institut National De La Recherche Agronomique Etablissement Public à Caractère Scientifique et Technologique 147, rue de l'Université 75007 Paris / FR | [2017/10] |
Former [2013/39] | For all designated states Institut National De La Recherche Agronomique Etablissement Public à Caractère Scientifique et Technologique 147, rue de l'Université 75007 Paris / FR | Inventor(s) | 01 /
MAUREL, Marie-Christine 126 rue du Cluzel F-37000 Tours / FR | 02 /
REITER, Eric La Tuilerie F-37380 Nouzilly / FR | 03 /
GUILLOU, Florian 52 rue Henri Martin F-37000 Tours / FR | 04 /
AUBREY, Nicolas 66 rue Charentais F-37320 Truyes / FR | [2013/39] | Representative(s) | Gevers & Orès Immeuble le Palatin 2 3 Cours du Triangle CS 80165 92939 Paris La Défense Cedex / FR | [N/P] |
Former [2017/10] | Gevers & Orès 41 avenue de Friedland 75008 Paris / FR | ||
Former [2014/23] | Rançon, Xavier Lucien Abel, et al Cabinet Orès 36 Rue de Saint Petersbourg 75008 Paris / FR | ||
Former [2013/39] | Métay, Émeline, et al Cabinet Orès 36, rue de St Pétersbourg 75008 Paris / FR | Application number, filing date | 11794861.2 | 21.11.2011 | [2017/10] | WO2011IB55210 | Priority number, date | FR20100004503 | 19.11.2010 Original published format: FR 1004503 | [2013/39] | Filing language | FR | Procedural language | FR | Publication | Type: | A1 Application with search report | No.: | WO2012066519 | Date: | 24.05.2012 | Language: | FR | [2012/21] | Type: | A1 Application with search report | No.: | EP2640748 | Date: | 25.09.2013 | Language: | FR | The application published by WIPO in one of the EPO official languages on 24.05.2012 takes the place of the publication of the European patent application. | [2013/39] | Type: | B1 Patent specification | No.: | EP2640748 | Date: | 08.03.2017 | Language: | FR | [2017/10] | Search report(s) | International search report - published on: | EP | 24.05.2012 | Classification | IPC: | C07K16/26, A61K39/395 | [2013/39] | CPC: |
C07K16/26 (EP,US);
A61P15/08 (EP);
A61K2039/505 (EP,US);
C07K2317/565 (EP,US);
C07K2317/567 (EP,US);
C07K2317/622 (EP,US)
| Designated contracting states | AL, AT, BE, BG, CH, CY, CZ, DE, DK, EE, ES, FI, FR, GB, GR, HR, HU, IE, IS, IT, LI, LT, LU, LV, MC, MK, MT, NL, NO, PL, PT, RO, RS, SE, SI, SK, SM, TR [2013/39] | Extension states | BA | Not yet paid | ME | Not yet paid | Title | German: | LUTEINISIERENDES HORMON-LIGAND UND LIGAND-GONADOTROPHIN-KOMPLEX | [2013/39] | English: | LUTEINIZING-HORMONE LIGAND AND LIGAND-GONADOTROPHIN COMPLEX | [2013/39] | French: | LIGAND D'HORMONE LUTEINISANTE ET COMPLEXE LIGAND-GONADOTROPHINE | [2013/39] | Entry into regional phase | 18.06.2013 | National basic fee paid | 18.06.2013 | Designation fee(s) paid | 18.06.2013 | Examination fee paid | Examination procedure | 18.06.2013 | Amendment by applicant (claims and/or description) | 18.06.2013 | Examination requested [2013/39] | 14.04.2014 | Despatch of a communication from the examining division (Time limit: M04) | 14.08.2014 | Reply to a communication from the examining division | 01.07.2015 | Despatch of a communication from the examining division (Time limit: M04) | 27.10.2015 | Reply to a communication from the examining division | 20.09.2016 | Communication of intention to grant the patent | 20.01.2017 | Fee for grant paid | 20.01.2017 | Fee for publishing/printing paid | 20.01.2017 | Receipt of the translation of the claim(s) | Divisional application(s) | The date of the Examining Division's first communication in respect of the earliest application for which a communication has been issued is 14.04.2014 | Opposition(s) | 11.12.2017 | No opposition filed within time limit [2018/07] | Fees paid | Renewal fee | 25.10.2013 | Renewal fee patent year 03 | 25.09.2014 | Renewal fee patent year 04 | 24.11.2015 | Renewal fee patent year 05 | 29.09.2016 | Renewal fee patent year 06 |
Opt-out from the exclusive Tooltip competence of the Unified Patent Court | See the Register of the Unified Patent Court for opt-out data | ||
Responsibility for the accuracy, completeness or quality of the data displayed under the link provided lies entirely with the Unified Patent Court. | Lapses during opposition Tooltip | HU | 21.11.2011 | AL | 08.03.2017 | AT | 08.03.2017 | CY | 08.03.2017 | CZ | 08.03.2017 | DK | 08.03.2017 | EE | 08.03.2017 | ES | 08.03.2017 | FI | 08.03.2017 | HR | 08.03.2017 | IT | 08.03.2017 | LT | 08.03.2017 | LV | 08.03.2017 | MC | 08.03.2017 | MK | 08.03.2017 | MT | 08.03.2017 | NL | 08.03.2017 | PL | 08.03.2017 | RO | 08.03.2017 | RS | 08.03.2017 | SE | 08.03.2017 | SI | 08.03.2017 | SK | 08.03.2017 | SM | 08.03.2017 | TR | 08.03.2017 | BG | 08.06.2017 | NO | 08.06.2017 | GR | 09.06.2017 | IS | 08.07.2017 | PT | 10.07.2017 | IE | 21.11.2017 | LU | 21.11.2017 | BE | 30.11.2017 | CH | 30.11.2017 | LI | 30.11.2017 | [2020/34] |
Former [2020/15] | HU | 21.11.2011 | |
AT | 08.03.2017 | ||
CY | 08.03.2017 | ||
CZ | 08.03.2017 | ||
DK | 08.03.2017 | ||
EE | 08.03.2017 | ||
ES | 08.03.2017 | ||
FI | 08.03.2017 | ||
HR | 08.03.2017 | ||
IT | 08.03.2017 | ||
LT | 08.03.2017 | ||
LV | 08.03.2017 | ||
MC | 08.03.2017 | ||
MK | 08.03.2017 | ||
MT | 08.03.2017 | ||
NL | 08.03.2017 | ||
PL | 08.03.2017 | ||
RO | 08.03.2017 | ||
RS | 08.03.2017 | ||
SE | 08.03.2017 | ||
SI | 08.03.2017 | ||
SK | 08.03.2017 | ||
SM | 08.03.2017 | ||
TR | 08.03.2017 | ||
BG | 08.06.2017 | ||
NO | 08.06.2017 | ||
GR | 09.06.2017 | ||
IS | 08.07.2017 | ||
PT | 10.07.2017 | ||
IE | 21.11.2017 | ||
LU | 21.11.2017 | ||
BE | 30.11.2017 | ||
CH | 30.11.2017 | ||
LI | 30.11.2017 | ||
Former [2019/51] | HU | 21.11.2011 | |
AT | 08.03.2017 | ||
CY | 08.03.2017 | ||
CZ | 08.03.2017 | ||
DK | 08.03.2017 | ||
EE | 08.03.2017 | ||
ES | 08.03.2017 | ||
FI | 08.03.2017 | ||
HR | 08.03.2017 | ||
IT | 08.03.2017 | ||
LT | 08.03.2017 | ||
LV | 08.03.2017 | ||
MC | 08.03.2017 | ||
MK | 08.03.2017 | ||
MT | 08.03.2017 | ||
NL | 08.03.2017 | ||
PL | 08.03.2017 | ||
RO | 08.03.2017 | ||
RS | 08.03.2017 | ||
SE | 08.03.2017 | ||
SI | 08.03.2017 | ||
SK | 08.03.2017 | ||
SM | 08.03.2017 | ||
BG | 08.06.2017 | ||
NO | 08.06.2017 | ||
GR | 09.06.2017 | ||
IS | 08.07.2017 | ||
PT | 10.07.2017 | ||
IE | 21.11.2017 | ||
LU | 21.11.2017 | ||
BE | 30.11.2017 | ||
CH | 30.11.2017 | ||
LI | 30.11.2017 | ||
Former [2019/46] | HU | 21.11.2011 | |
AT | 08.03.2017 | ||
CY | 08.03.2017 | ||
CZ | 08.03.2017 | ||
DK | 08.03.2017 | ||
EE | 08.03.2017 | ||
ES | 08.03.2017 | ||
FI | 08.03.2017 | ||
HR | 08.03.2017 | ||
IT | 08.03.2017 | ||
LT | 08.03.2017 | ||
LV | 08.03.2017 | ||
MC | 08.03.2017 | ||
MT | 08.03.2017 | ||
NL | 08.03.2017 | ||
PL | 08.03.2017 | ||
RO | 08.03.2017 | ||
RS | 08.03.2017 | ||
SE | 08.03.2017 | ||
SI | 08.03.2017 | ||
SK | 08.03.2017 | ||
SM | 08.03.2017 | ||
BG | 08.06.2017 | ||
NO | 08.06.2017 | ||
GR | 09.06.2017 | ||
IS | 08.07.2017 | ||
PT | 10.07.2017 | ||
IE | 21.11.2017 | ||
LU | 21.11.2017 | ||
BE | 30.11.2017 | ||
CH | 30.11.2017 | ||
LI | 30.11.2017 | ||
Former [2019/31] | HU | 21.11.2011 | |
AT | 08.03.2017 | ||
CZ | 08.03.2017 | ||
DK | 08.03.2017 | ||
EE | 08.03.2017 | ||
ES | 08.03.2017 | ||
FI | 08.03.2017 | ||
HR | 08.03.2017 | ||
IT | 08.03.2017 | ||
LT | 08.03.2017 | ||
LV | 08.03.2017 | ||
MC | 08.03.2017 | ||
MT | 08.03.2017 | ||
NL | 08.03.2017 | ||
PL | 08.03.2017 | ||
RO | 08.03.2017 | ||
RS | 08.03.2017 | ||
SE | 08.03.2017 | ||
SI | 08.03.2017 | ||
SK | 08.03.2017 | ||
SM | 08.03.2017 | ||
BG | 08.06.2017 | ||
NO | 08.06.2017 | ||
GR | 09.06.2017 | ||
IS | 08.07.2017 | ||
PT | 10.07.2017 | ||
IE | 21.11.2017 | ||
LU | 21.11.2017 | ||
BE | 30.11.2017 | ||
CH | 30.11.2017 | ||
LI | 30.11.2017 | ||
Former [2018/50] | AT | 08.03.2017 | |
CZ | 08.03.2017 | ||
DK | 08.03.2017 | ||
EE | 08.03.2017 | ||
ES | 08.03.2017 | ||
FI | 08.03.2017 | ||
HR | 08.03.2017 | ||
IT | 08.03.2017 | ||
LT | 08.03.2017 | ||
LV | 08.03.2017 | ||
MC | 08.03.2017 | ||
MT | 08.03.2017 | ||
NL | 08.03.2017 | ||
PL | 08.03.2017 | ||
RO | 08.03.2017 | ||
RS | 08.03.2017 | ||
SE | 08.03.2017 | ||
SI | 08.03.2017 | ||
SK | 08.03.2017 | ||
SM | 08.03.2017 | ||
BG | 08.06.2017 | ||
NO | 08.06.2017 | ||
GR | 09.06.2017 | ||
IS | 08.07.2017 | ||
PT | 10.07.2017 | ||
IE | 21.11.2017 | ||
LU | 21.11.2017 | ||
BE | 30.11.2017 | ||
CH | 30.11.2017 | ||
LI | 30.11.2017 | ||
Former [2018/45] | AT | 08.03.2017 | |
CZ | 08.03.2017 | ||
DK | 08.03.2017 | ||
EE | 08.03.2017 | ||
ES | 08.03.2017 | ||
FI | 08.03.2017 | ||
HR | 08.03.2017 | ||
IT | 08.03.2017 | ||
LT | 08.03.2017 | ||
LV | 08.03.2017 | ||
MC | 08.03.2017 | ||
MT | 08.03.2017 | ||
NL | 08.03.2017 | ||
PL | 08.03.2017 | ||
RO | 08.03.2017 | ||
RS | 08.03.2017 | ||
SE | 08.03.2017 | ||
SI | 08.03.2017 | ||
SK | 08.03.2017 | ||
SM | 08.03.2017 | ||
BG | 08.06.2017 | ||
NO | 08.06.2017 | ||
GR | 09.06.2017 | ||
IS | 08.07.2017 | ||
PT | 10.07.2017 | ||
IE | 21.11.2017 | ||
LU | 21.11.2017 | ||
CH | 30.11.2017 | ||
LI | 30.11.2017 | ||
Former [2018/43] | AT | 08.03.2017 | |
CZ | 08.03.2017 | ||
DK | 08.03.2017 | ||
EE | 08.03.2017 | ||
ES | 08.03.2017 | ||
FI | 08.03.2017 | ||
HR | 08.03.2017 | ||
IT | 08.03.2017 | ||
LT | 08.03.2017 | ||
LV | 08.03.2017 | ||
MC | 08.03.2017 | ||
MT | 08.03.2017 | ||
NL | 08.03.2017 | ||
PL | 08.03.2017 | ||
RO | 08.03.2017 | ||
RS | 08.03.2017 | ||
SE | 08.03.2017 | ||
SI | 08.03.2017 | ||
SK | 08.03.2017 | ||
SM | 08.03.2017 | ||
BG | 08.06.2017 | ||
NO | 08.06.2017 | ||
GR | 09.06.2017 | ||
IS | 08.07.2017 | ||
PT | 10.07.2017 | ||
LU | 21.11.2017 | ||
CH | 30.11.2017 | ||
LI | 30.11.2017 | ||
Former [2018/41] | AT | 08.03.2017 | |
CZ | 08.03.2017 | ||
DK | 08.03.2017 | ||
EE | 08.03.2017 | ||
ES | 08.03.2017 | ||
FI | 08.03.2017 | ||
HR | 08.03.2017 | ||
IT | 08.03.2017 | ||
LT | 08.03.2017 | ||
LV | 08.03.2017 | ||
MC | 08.03.2017 | ||
NL | 08.03.2017 | ||
PL | 08.03.2017 | ||
RO | 08.03.2017 | ||
RS | 08.03.2017 | ||
SE | 08.03.2017 | ||
SI | 08.03.2017 | ||
SK | 08.03.2017 | ||
SM | 08.03.2017 | ||
BG | 08.06.2017 | ||
NO | 08.06.2017 | ||
GR | 09.06.2017 | ||
IS | 08.07.2017 | ||
PT | 10.07.2017 | ||
LU | 21.11.2017 | ||
CH | 30.11.2017 | ||
LI | 30.11.2017 | ||
Former [2018/33] | AT | 08.03.2017 | |
CZ | 08.03.2017 | ||
DK | 08.03.2017 | ||
EE | 08.03.2017 | ||
ES | 08.03.2017 | ||
FI | 08.03.2017 | ||
HR | 08.03.2017 | ||
IT | 08.03.2017 | ||
LT | 08.03.2017 | ||
LV | 08.03.2017 | ||
MC | 08.03.2017 | ||
NL | 08.03.2017 | ||
PL | 08.03.2017 | ||
RO | 08.03.2017 | ||
RS | 08.03.2017 | ||
SE | 08.03.2017 | ||
SI | 08.03.2017 | ||
SK | 08.03.2017 | ||
SM | 08.03.2017 | ||
BG | 08.06.2017 | ||
NO | 08.06.2017 | ||
GR | 09.06.2017 | ||
IS | 08.07.2017 | ||
PT | 10.07.2017 | ||
CH | 30.11.2017 | ||
LI | 30.11.2017 | ||
Former [2018/14] | AT | 08.03.2017 | |
CZ | 08.03.2017 | ||
DK | 08.03.2017 | ||
EE | 08.03.2017 | ||
ES | 08.03.2017 | ||
FI | 08.03.2017 | ||
HR | 08.03.2017 | ||
IT | 08.03.2017 | ||
LT | 08.03.2017 | ||
LV | 08.03.2017 | ||
NL | 08.03.2017 | ||
PL | 08.03.2017 | ||
RO | 08.03.2017 | ||
RS | 08.03.2017 | ||
SE | 08.03.2017 | ||
SI | 08.03.2017 | ||
SK | 08.03.2017 | ||
SM | 08.03.2017 | ||
BG | 08.06.2017 | ||
NO | 08.06.2017 | ||
GR | 09.06.2017 | ||
IS | 08.07.2017 | ||
PT | 10.07.2017 | ||
Former [2018/09] | AT | 08.03.2017 | |
CZ | 08.03.2017 | ||
DK | 08.03.2017 | ||
EE | 08.03.2017 | ||
ES | 08.03.2017 | ||
FI | 08.03.2017 | ||
HR | 08.03.2017 | ||
IT | 08.03.2017 | ||
LT | 08.03.2017 | ||
LV | 08.03.2017 | ||
NL | 08.03.2017 | ||
PL | 08.03.2017 | ||
RO | 08.03.2017 | ||
RS | 08.03.2017 | ||
SE | 08.03.2017 | ||
SK | 08.03.2017 | ||
SM | 08.03.2017 | ||
BG | 08.06.2017 | ||
NO | 08.06.2017 | ||
GR | 09.06.2017 | ||
IS | 08.07.2017 | ||
PT | 10.07.2017 | ||
Former [2017/51] | AT | 08.03.2017 | |
CZ | 08.03.2017 | ||
EE | 08.03.2017 | ||
ES | 08.03.2017 | ||
FI | 08.03.2017 | ||
HR | 08.03.2017 | ||
IT | 08.03.2017 | ||
LT | 08.03.2017 | ||
LV | 08.03.2017 | ||
NL | 08.03.2017 | ||
PL | 08.03.2017 | ||
RO | 08.03.2017 | ||
RS | 08.03.2017 | ||
SE | 08.03.2017 | ||
SK | 08.03.2017 | ||
SM | 08.03.2017 | ||
BG | 08.06.2017 | ||
NO | 08.06.2017 | ||
GR | 09.06.2017 | ||
IS | 08.07.2017 | ||
PT | 10.07.2017 | ||
Former [2017/50] | AT | 08.03.2017 | |
CZ | 08.03.2017 | ||
EE | 08.03.2017 | ||
ES | 08.03.2017 | ||
FI | 08.03.2017 | ||
HR | 08.03.2017 | ||
IT | 08.03.2017 | ||
LT | 08.03.2017 | ||
LV | 08.03.2017 | ||
NL | 08.03.2017 | ||
PL | 08.03.2017 | ||
RO | 08.03.2017 | ||
RS | 08.03.2017 | ||
SE | 08.03.2017 | ||
SK | 08.03.2017 | ||
BG | 08.06.2017 | ||
NO | 08.06.2017 | ||
GR | 09.06.2017 | ||
IS | 08.07.2017 | ||
Former [2017/49] | AT | 08.03.2017 | |
CZ | 08.03.2017 | ||
EE | 08.03.2017 | ||
ES | 08.03.2017 | ||
FI | 08.03.2017 | ||
HR | 08.03.2017 | ||
IT | 08.03.2017 | ||
LT | 08.03.2017 | ||
LV | 08.03.2017 | ||
NL | 08.03.2017 | ||
RO | 08.03.2017 | ||
RS | 08.03.2017 | ||
SE | 08.03.2017 | ||
SK | 08.03.2017 | ||
BG | 08.06.2017 | ||
NO | 08.06.2017 | ||
GR | 09.06.2017 | ||
IS | 08.07.2017 | ||
Former [2017/48] | CZ | 08.03.2017 | |
ES | 08.03.2017 | ||
FI | 08.03.2017 | ||
HR | 08.03.2017 | ||
LT | 08.03.2017 | ||
LV | 08.03.2017 | ||
NL | 08.03.2017 | ||
RS | 08.03.2017 | ||
SE | 08.03.2017 | ||
BG | 08.06.2017 | ||
NO | 08.06.2017 | ||
GR | 09.06.2017 | ||
Former [2017/41] | ES | 08.03.2017 | |
FI | 08.03.2017 | ||
HR | 08.03.2017 | ||
LT | 08.03.2017 | ||
LV | 08.03.2017 | ||
NL | 08.03.2017 | ||
RS | 08.03.2017 | ||
SE | 08.03.2017 | ||
BG | 08.06.2017 | ||
NO | 08.06.2017 | ||
GR | 09.06.2017 | Cited in | International search | [I]US2002102613 (HOOGENBOOM HENDRICUS RENERUS J [NL]) [I] 1 * paragraph [0377] *; | [AD]EP1518863 (INST NAT DE LARECH AGRONOMIQUE [FR], et al) [AD] 1-12 * the whole document *; | [A]EP0137234 (WELLCOME FOUND [GB]) [A] 1-12 * the whole document *; | [A]US2003092082 (ACEVEDO HERNAN [US], et al) [A] 1-12 * the whole document *; | [I] - CHOPINEAU M ET AL, "Topography of equine chorionic gonadotropin epitopes relative to the luteinizing hormone and follicle-stimulating hormone receptor interaction sites", MOLECULAR AND CELLULAR ENDOCRINOLOGY, ELSEVIER IRELAND LTD, IE, vol. 92, no. 2, doi:DOI:10.1016/0303-7207(93)90013-A, ISSN 0303-7207, (19930401), pages 229 - 239, (19930401), XP023489202 [I] 5-12 * figure 4 * DOI: http://dx.doi.org/10.1016/0303-7207(93)90013-A | [A] - GLENCROSS R G ET AL, "Monoclonal antibody enhancement of FSH-induced uterine growth in snell dwarf mice", JOURNAL OF ENDOCRINOLOGY, SOCIETY FOR ENDOCRINOLOGY, GB, (19930301), vol. 136, no. 3, ISSN 0022-0795, pages R5 - R7, XP009145848 [A] 1-12 * the whole document * DOI: http://dx.doi.org/10.1677/joe.0.136R005 | [A] - WEHBI VANESSA ET AL, "Selective modulation of follicle-stimulating hormone signaling pathways with enhancing equine chorionic gonadotropin/antibody immune complexes.", ENDOCRINOLOGY JUN 2010 LNKD- PUBMED:20332198, (201006), vol. 151, no. 6, ISSN 1945-7170, pages 2788 - 2799, XP009145847 [A] 1-12 * the whole document * | by applicant | EP1518863 | - GIUDICELLI ET AL., NUCLEIC ACIDS RESEARCH, (2004), vol. 32, pages W435 - W440 | - BROCHET, X. ET AL., NUCL. ACIDS RES., (2008), vol. 36, pages W503 - 508 | - "Reshaping antibodies for therapy", ROUTLEDGE ET AL., Protein Engineering of Antibody Molecules for Prophylatic and Therapeutic Applications in Man, ACADEMIC TITLES, (1993), pages 13 - 44 | - ROGUSKA ET AL., PROTEIN ENGINEERING, (1996), vol. 9, no. 10, pages 895 - 904 | - CLACKSON ET AL., NATURE, (1991), vol. 352, pages 624 - 628 | - PETER ET AL., THE JOURNAL OF BIOLOGICAL CHEMISTRY, (2003), vol. 278, pages 36740 - 36747 | - MOUSLI M. ET AL., FEBS LETTERS, (1999), vol. 442, pages 183 - 188 | - F. CORPET, NUCL. ACIDS RES., (1988), vol. 16, no. 22, pages 10881 - 10890 | - KAAS Q ET AL., NUCLEIC ACID RESEARCH, (2004), vol. 32, pages 208 - 210 | - SCOBEY MJ ET AL., REPROD. BIOL. ENDOCR., (2005), vol. 3, page 61 | - PARLOW A F, FED. PROC., (1958), vol. 17, page 402 | - BIRD ET AL., SCIENCE, (1988), vol. 242, no. 4877, pages 423 - 426 | - WHITLOW ET AL., PROTEIN ENG., (1994), vol. 7, no. 8, pages 1017 - 1026 | - CYSTER ET AL., EUROPEAN JOURNAL OF IMMUNOLOGY, (1992), vol. 22, no. 10, pages 2565 - 2572 | - MARTINAT ET AL., REPROD NUTR DEV., (2005), vol. 45, no. 1, pages 101 - 8 | - STEELMAN SL; POHLEY FM, ENDOCRINOLOGY, (1953), vol. 53, pages 604 - 616 | - COGNIÉ J., REVUE MED.VET., (2007), vol. 158, pages 8 - 9,447-451 | - CAHIERS TECHNIQUES INRA, (2008), vol. 64, pages 19 - 30 |