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Extract from the Register of European Patents

EP About this file: EP2586863

EP2586863 - HIGH-SPEED MATURATION METHOD FOR AN OLIGONUCLEOTIDE LIBRARY FOR THE PURPOSE OF PREPARING A PROTEIN LIBRARY [Right-click to bookmark this link]
StatusNo opposition filed within time limit
Status updated on  09.03.2018
Database last updated on 20.09.2024
FormerThe patent has been granted
Status updated on  31.03.2017
FormerGrant of patent is intended
Status updated on  25.03.2017
FormerExamination is in progress
Status updated on  01.03.2017
FormerGrant of patent is intended
Status updated on  27.02.2017
Most recent event   Tooltip10.07.2020Lapse of the patent in a contracting state
New state(s): AL		published on 12.08.2020  [2020/33]
Applicant(s)For all designated states
The University of Tokyo
3-1, Hongo 7-chome
Bunkyo-ku
Tokyo 113-8654 / JP
For all designated states
GeneFrontier Corporation
Todai-Kashiwa Venture Plaza Rm No. 308
5-4-19, Kashiwa-no-Ha
Kashiwa-shi
Chiba 277-0882 / JP
[2017/11]
Former [2013/18]For all designated states
The University of Tokyo
3-1, Hongo 7-chome Bunkyo-Ku
Tokyo 113-8654 / JP
For all designated states
GeneFrontier Corporation
Todai-Kashiwa Venture Plaza Rm 308
5-4-19, Kashiwa-no-Ha
Kashiwa-shi
Chiba 277-0882 / JP
Inventor(s)01 / UEDA, Takuya
c/o The University of Tokyo
3-1, Hongo 7-chome
Bunkyo-ku
Tokyo 113-8654 / JP
02 / KANAMORI, Takashi
c/o GeneFrontier Corporation
Todai-Kashiwa Venture Plaza Rm. No. 308
5-4-19, Kashiwa-no-Ha, Kashiwa-shi
Chiba 2770882 / JP
03 / KOJOH, Kanehisa
c/o GeneFrontier Corporation
Todai-Kashiwa Venture Plaza Rm No. 308
5-4-19, Kashiwa-no-Ha
Kashiwa-shi Chiba 277-0882 / JP
04 / KATOH, Shizue
c/o GeneFrontier Corporation
Todai-Kashiwa Venture Plaza Rm No. 308
5-4-19, Kashiwa-no-Ha
Kashiwa-shi Chiba 277-0882 / JP
05 / MIYAKOSHI, Akira
c/o GeneFrontier Corporation
Todai-Kashiwa Venture Plaza Rm No. 308
5-4-19, Kashiwa-no-Ha
Kashiwa-shi Chiba 277-0882 / JP
 [2017/18]
Former [2013/29]01 / UEDA, Takuya
c/o The University of Tokyo
3-1, Hongo 7-chome
Bunkyo-ku
Tokyo 113-8654 / JP
02 / KANAMORI, Takashi
c/o GeneFrontier Corporation
Todai-Kashiwa Venture Plaza Rm. 308
5-4-19, Kashiwa-no-Ha, Kashiwa-shi
Chiba 2770882 / JP
03 / KOJOH, Kanehisa
c/o GeneFrontier Corporation
Todai-Kashiwa Venture Plaza Rm 308
5-4-19, Kashiwa-no-Ha
Kashiwa-shi Chiba 277-0882 / JP
04 / KATOH, Shizue
c/o GeneFrontier Corporation
Todai-Kashiwa Venture Plaza Rm 308
5-4-19, Kashiwa-no-Ha
Kashiwa-shi Chiba 277-0882 / JP
05 / MIYAKOSHI, Akira
c/o GeneFrontier Corporation
Todai-Kashiwa Venture Plaza Rm 308
5-4-19, Kashiwa-no-Ha
Kashiwa-shi Chiba 277-0882 / JP
Former [2013/18]01 / UEDA, Takuya
c/o The University of Tokyo
3-1, Hongo 7-chome
Bunkyo-ku
Tokyo 113-8654 / JP
02 / KANAMORI, Takashi
c/o GeneFrontier Corporation
Todai-Kashiwa Venture Plaza Rm. 308
5-4-19, Kashiwa-no-Ha, Kashiwa-shi
Chiba 2770882 / JP
03 / KOJOH, Kanehisa
c/o GeneFrontier Corporation
Todai-Kashiwa Venture Plaza Rm 308
5-4-19, Kashiwa-no-Ha
Kashiwa-shi Chiba 277-0882 / JP
04 / KATOH, Shizue
c/o GeneFrontier Corporation
Todai-Kashiwa Venture Plaza Rm 308
5-4-19, Kashiwa-no-Ha
Kashiwa-shi Chiba 277-0882 / JP
05 / MIYAKOSHI, Akira
c/o GeneFrontier Corporation
Todai-Kashiwa Venture Plaza Rm 308
5-4-19, Kashiwa-no-Ha
Kashiwa-shi Chiba 277-0882 / JP
Representative(s)J A Kemp LLP
80 Turnmill Street
London EC1M 5QU / GB
[N/P]
Former [2013/18]Duckworth, Timothy John
J A Kemp
14 South Square
Gray's Inn
London WC1R 5JJ / GB
Application number, filing date11798236.323.06.2011
[2017/18]
WO2011JP64455
Priority number, dateJP2010014247023.06.2010         Original published format: JP 2010142470
[2013/18]
Filing languageJA
Procedural languageEN
PublicationType: A1 Application with search report
No.:WO2011162355
Date:29.12.2011
Language:JA
[2011/52]
Type: A1 Application with search report 
No.:EP2586863
Date:01.05.2013
Language:EN
[2013/18]
Type: B1 Patent specification 
No.:EP2586863
Date:03.05.2017
Language:EN
[2017/18]
Search report(s)International search report - published on:JP29.12.2011
(Supplementary) European search report - dispatched on:EP27.11.2013
ClassificationIPC:C12N15/10
[2013/52]
CPC:
C12N15/1065 (EP,US); C12N15/1041 (EP,US); C12N15/1093 (US);
C12N15/67 (US)
Former IPC [2013/18]C12N15/09
Designated contracting statesAL,   AT,   BE,   BG,   CH,   CY,   CZ,   DE,   DK,   EE,   ES,   FI,   FR,   GB,   GR,   HR,   HU,   IE,   IS,   IT,   LI,   LT,   LU,   LV,   MC,   MK,   MT,   NL,   NO,   PL,   PT,   RO,   RS,   SE,   SI,   SK,   SM,   TR [2013/18]
Extension statesBANot yet paid
MENot yet paid
TitleGerman:HOCHGESCHWINDIGKEITS-REIFUNGSVERFAHREN FÜR EINE OLIGONUKLEOTID-BIBLIOTHEK ZUM ZWECK DER ERSTELLUNG EINER PROTEIN-BIBLIOTHEK[2013/18]
English:HIGH-SPEED MATURATION METHOD FOR AN OLIGONUCLEOTIDE LIBRARY FOR THE PURPOSE OF PREPARING A PROTEIN LIBRARY[2013/18]
French:PROCÉDÉ DE MATURATION À GRANDE VITESSE D'UNE BANQUE D'OLIGONUCLÉOTIDES DANS LE BUT DE PRÉPARER UNE BANQUE DE PROTÉINES[2013/18]
Entry into regional phase04.01.2013Translation filed 
04.01.2013National basic fee paid 
04.01.2013Search fee paid 
04.01.2013Designation fee(s) paid 
04.01.2013Examination fee paid 
Examination procedure04.01.2013Examination requested  [2013/18]
23.06.2014Amendment by applicant (claims and/or description)
28.09.2015Despatch of a communication from the examining division (Time limit: M04)
28.01.2016Reply to a communication from the examining division
24.03.2016Despatch of a communication from the examining division (Time limit: M04)
03.08.2016Reply to a communication from the examining division
26.10.2016Communication of intention to grant the patent
23.02.2017Disapproval of the communication of intention to grant the patent by the applicant or resumption of examination proceedings by the EPO
23.02.2017Fee for grant paid
23.02.2017Fee for publishing/printing paid
24.03.2017Information about intention to grant a patent
24.03.2017Receipt of the translation of the claim(s)
Divisional application(s)The date of the Examining Division's first communication in respect of the earliest application for which a communication has been issued is  28.09.2015
Opposition(s)06.02.2018No opposition filed within time limit [2018/15]
Fees paidRenewal fee
10.06.2013Renewal fee patent year 03
12.06.2014Renewal fee patent year 04
10.06.2015Renewal fee patent year 05
10.06.2016Renewal fee patent year 06
Opt-out from the exclusive  Tooltip
competence of the Unified
Patent Court		 See the Register of the Unified Patent Court for opt-out data
Responsibility for the accuracy, completeness or quality of the data displayed under the link provided lies entirely with the Unified Patent Court.
Lapses during opposition  TooltipHU23.06.2011
AL03.05.2017
AT03.05.2017
CY03.05.2017
CZ03.05.2017
DK03.05.2017
EE03.05.2017
ES03.05.2017
FI03.05.2017
HR03.05.2017
IT03.05.2017
LT03.05.2017
LV03.05.2017
MC03.05.2017
MK03.05.2017
NL03.05.2017
PL03.05.2017
PT03.05.2017
RO03.05.2017
RS03.05.2017
SE03.05.2017
SI03.05.2017
SK03.05.2017
SM03.05.2017
TR03.05.2017
IE23.06.2017
LU23.06.2017
MT23.06.2017
BG03.08.2017
NO03.08.2017
GR04.08.2017
IS03.09.2017
[2020/33]
Former [2020/27]HU23.06.2011
AT03.05.2017
CY03.05.2017
CZ03.05.2017
DK03.05.2017
EE03.05.2017
ES03.05.2017
FI03.05.2017
HR03.05.2017
IT03.05.2017
LT03.05.2017
LV03.05.2017
MC03.05.2017
MK03.05.2017
NL03.05.2017
PL03.05.2017
PT03.05.2017
RO03.05.2017
RS03.05.2017
SE03.05.2017
SI03.05.2017
SK03.05.2017
SM03.05.2017
TR03.05.2017
IE23.06.2017
LU23.06.2017
MT23.06.2017
BG03.08.2017
NO03.08.2017
GR04.08.2017
IS03.09.2017
Former [2020/15]HU23.06.2011
AT03.05.2017
CY03.05.2017
CZ03.05.2017
DK03.05.2017
EE03.05.2017
ES03.05.2017
FI03.05.2017
HR03.05.2017
IT03.05.2017
LT03.05.2017
LV03.05.2017
MC03.05.2017
MK03.05.2017
NL03.05.2017
PL03.05.2017
RO03.05.2017
RS03.05.2017
SE03.05.2017
SI03.05.2017
SK03.05.2017
SM03.05.2017
TR03.05.2017
IE23.06.2017
LU23.06.2017
MT23.06.2017
BG03.08.2017
NO03.08.2017
GR04.08.2017
IS03.09.2017
Former [2019/51]HU23.06.2011
AT03.05.2017
CY03.05.2017
CZ03.05.2017
DK03.05.2017
EE03.05.2017
ES03.05.2017
FI03.05.2017
HR03.05.2017
IT03.05.2017
LT03.05.2017
LV03.05.2017
MC03.05.2017
MK03.05.2017
NL03.05.2017
PL03.05.2017
RO03.05.2017
RS03.05.2017
SE03.05.2017
SI03.05.2017
SK03.05.2017
SM03.05.2017
IE23.06.2017
LU23.06.2017
MT23.06.2017
BG03.08.2017
NO03.08.2017
GR04.08.2017
IS03.09.2017
Former [2019/46]HU23.06.2011
AT03.05.2017
CY03.05.2017
CZ03.05.2017
DK03.05.2017
EE03.05.2017
ES03.05.2017
FI03.05.2017
HR03.05.2017
IT03.05.2017
LT03.05.2017
LV03.05.2017
MC03.05.2017
NL03.05.2017
PL03.05.2017
RO03.05.2017
RS03.05.2017
SE03.05.2017
SI03.05.2017
SK03.05.2017
SM03.05.2017
IE23.06.2017
LU23.06.2017
MT23.06.2017
BG03.08.2017
NO03.08.2017
GR04.08.2017
IS03.09.2017
Former [2019/31]HU23.06.2011
AT03.05.2017
CZ03.05.2017
DK03.05.2017
EE03.05.2017
ES03.05.2017
FI03.05.2017
HR03.05.2017
IT03.05.2017
LT03.05.2017
LV03.05.2017
MC03.05.2017
NL03.05.2017
PL03.05.2017
RO03.05.2017
RS03.05.2017
SE03.05.2017
SI03.05.2017
SK03.05.2017
SM03.05.2017
IE23.06.2017
LU23.06.2017
MT23.06.2017
BG03.08.2017
NO03.08.2017
GR04.08.2017
IS03.09.2017
Former [2019/30]AT03.05.2017
CZ03.05.2017
DK03.05.2017
EE03.05.2017
ES03.05.2017
FI03.05.2017
HR03.05.2017
IT03.05.2017
LT03.05.2017
LV03.05.2017
MC03.05.2017
NL03.05.2017
PL03.05.2017
RO03.05.2017
RS03.05.2017
SE03.05.2017
SI03.05.2017
SK03.05.2017
SM03.05.2017
IE23.06.2017
LU23.06.2017
MT23.06.2017
BG03.08.2017
NO03.08.2017
GR04.08.2017
IS03.09.2017
Former [2018/43]AT03.05.2017
CZ03.05.2017
DK03.05.2017
EE03.05.2017
ES03.05.2017
FI03.05.2017
HR03.05.2017
IT03.05.2017
LT03.05.2017
LV03.05.2017
NL03.05.2017
PL03.05.2017
RO03.05.2017
RS03.05.2017
SE03.05.2017
SI03.05.2017
SK03.05.2017
SM03.05.2017
IE23.06.2017
LU23.06.2017
MT23.06.2017
BG03.08.2017
NO03.08.2017
GR04.08.2017
IS03.09.2017
Former [2018/23]AT03.05.2017
CZ03.05.2017
DK03.05.2017
EE03.05.2017
ES03.05.2017
FI03.05.2017
HR03.05.2017
IT03.05.2017
LT03.05.2017
LV03.05.2017
NL03.05.2017
PL03.05.2017
RO03.05.2017
RS03.05.2017
SE03.05.2017
SI03.05.2017
SK03.05.2017
SM03.05.2017
IE23.06.2017
LU23.06.2017
BG03.08.2017
NO03.08.2017
GR04.08.2017
IS03.09.2017
Former [2018/21]AT03.05.2017
CZ03.05.2017
DK03.05.2017
EE03.05.2017
ES03.05.2017
FI03.05.2017
HR03.05.2017
IT03.05.2017
LT03.05.2017
LV03.05.2017
NL03.05.2017
PL03.05.2017
RO03.05.2017
RS03.05.2017
SE03.05.2017
SK03.05.2017
SM03.05.2017
LU23.06.2017
BG03.08.2017
NO03.08.2017
GR04.08.2017
IS03.09.2017
Former [2018/11]AT03.05.2017
CZ03.05.2017
DK03.05.2017
EE03.05.2017
ES03.05.2017
FI03.05.2017
HR03.05.2017
IT03.05.2017
LT03.05.2017
LV03.05.2017
NL03.05.2017
PL03.05.2017
RO03.05.2017
RS03.05.2017
SE03.05.2017
SK03.05.2017
SM03.05.2017
BG03.08.2017
NO03.08.2017
GR04.08.2017
IS03.09.2017
Former [2018/10]AT03.05.2017
CZ03.05.2017
DK03.05.2017
EE03.05.2017
ES03.05.2017
FI03.05.2017
HR03.05.2017
LT03.05.2017
LV03.05.2017
NL03.05.2017
PL03.05.2017
RO03.05.2017
RS03.05.2017
SE03.05.2017
SK03.05.2017
BG03.08.2017
NO03.08.2017
GR04.08.2017
IS03.09.2017
Former [2018/09]AT03.05.2017
DK03.05.2017
EE03.05.2017
ES03.05.2017
FI03.05.2017
HR03.05.2017
LT03.05.2017
LV03.05.2017
NL03.05.2017
PL03.05.2017
RS03.05.2017
SE03.05.2017
BG03.08.2017
NO03.08.2017
GR04.08.2017
IS03.09.2017
Former [2017/52]AT03.05.2017
ES03.05.2017
FI03.05.2017
HR03.05.2017
LT03.05.2017
LV03.05.2017
NL03.05.2017
PL03.05.2017
RS03.05.2017
SE03.05.2017
BG03.08.2017
NO03.08.2017
GR04.08.2017
IS03.09.2017
Former [2017/50]AT03.05.2017
ES03.05.2017
FI03.05.2017
HR03.05.2017
LT03.05.2017
LV03.05.2017
PL03.05.2017
RS03.05.2017
SE03.05.2017
BG03.08.2017
NO03.08.2017
GR04.08.2017
IS03.09.2017
Former [2017/49]AT03.05.2017
ES03.05.2017
FI03.05.2017
HR03.05.2017
LT03.05.2017
NO03.08.2017
GR04.08.2017
IS03.09.2017
Documents cited:Search[I]  - ERIKO OSADA ET AL, "Epitope Mapping Using Ribosome Display in a Reconstituted Cell-Free Protein Synthesis System", vol. 145, no. 5, doi:10.1093/JB/MVP027, ISSN 0021-924X, (20090501), pages 693 - 700, JOURNAL OF BIOCHEMISTRY, JAPANESE BIOCHEMICAL SOCIETY / OUP, TOKYO; JP, URL: http://jb.oxfordjournals.org/content/145/5/693, (20090219), XP002677147 [I] 1-7 * page 694, column l, paragraph 2 * * page 694, column r, paragraph 2 * * page 695, column l, paragraph 2 - page 695, column r, paragraph 3; figures 1,2 *

DOI:   http://dx.doi.org/10.1093/JB/MVP027
 [A]  - OHASHI ET AL, "Efficient protein selection based on ribosome display system with purified components", BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS, ACADEMIC PRESS INC. ORLANDO, FL, US, (20061130), vol. 352, no. 1, doi:10.1016/J.BBRC.2006.11.017, ISSN 0006-291X, pages 270 - 276, XP005727956 [A] 1-7 * the whole document *

DOI:   http://dx.doi.org/10.1016/j.bbrc.2006.11.017
 [A]  - SHIMIZU Y ET AL, "Protein synthesis by pure translation systems", METHODS : A COMPANION TO METHODS IN ENZYMOLOGY, ACADEMIC PRESS INC., NEW YORK, NY, US, vol. 36, no. 3, ISSN 1046-2023, (20050701), pages 299 - 304, (20050731), XP027216576 [A] 1-7 * the whole document *
International search[Y]JP2007029061  (NAT INST OF ADV IND & TECHNOL);
 [A]JP2008271903  (UNIV TOKYO);
 [X]JP2009112286  (UEDA TAKUYA);
 [A]  - OSADA E. ET AL., "Epitope mapping using ribosome display in a reconstituted cell-free protein synthesis system", THE JOURNAL OF BIOCHEMISTRY, (2009), vol. 145, no. 5, pages 693 - 700, XP002677147

DOI:   http://dx.doi.org/10.1093/JB/MVP027
Examination   - CHO G ET AL, "Constructing high complexity synthetic libraries of long ORFs using In Vitro selection", JOURNAL OF MOLECULAR BIOLOGY, ACADEMIC PRESS, UNITED KINGDOM, (20000324), vol. 297, no. 2, doi:10.1006/JMBI.2000.3571, ISSN 0022-2836, pages 309 - 319, XP004461609

DOI:   http://dx.doi.org/10.1006/jmbi.2000.3571
by applicantJP2008271903
    - NAKATOGAWA; ITO, CELL, (2002), vol. 108, pages 629 - 636
    - GONG ET AL., SCIENCE, (2002), vol. 297, pages 1864 - 1867
    - TANNER ET AL., J. BIOL. CHEM, (2009), vol. 284, pages 34809 - 34818
    - HOOD ET AL., ANNU. REV. MICROBIOL, (2009), vol. 63, pages 385 - 409
    - SHIMIZU Y; INOUE A; TOMARI Y; SUZUKI T; YOKOGAWA T; NISHIKAWA K; UEDA T, "Cell-free translation reconstituted with purified components", NATURE BIOTECHNOLOGY, (2001), vol. 19, pages 751 - 755
    - VILLEMAGNE ET AL., J. IMMUNOL. METHODS, (2006), vol. 313, pages 140 - 148
    - MOORE; SAUER, ANNU. REV. BIOCHEM., (2007), vol. 76, pages 101 - 124
    - HANES ET AL., PROC. NATL. ACAD. SCI. USA, (1997), vol. 94, pages 4937 - 4942
    - SHIMIZU ET AL., METHODS, (2005), vol. 36, pages 299 - 304
The EPO accepts no responsibility for the accuracy of data originating from other authorities; in particular, it does not guarantee that it is complete, up to date or fit for specific purposes.