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Extract from the Register of European Patents

EP About this file: EP2617810

EP2617810 - METHOD FOR PRODUCING LAYERED CELL SHEETS, LAYERED CELL SHEETS HAVING VASCULAR NETWORK OBTAINED THEREBY, AND METHOD FOR UTILIZING SAME [Right-click to bookmark this link]
StatusNo opposition filed within time limit
Status updated on  17.02.2017
Database last updated on 18.01.2025
Most recent event   Tooltip12.10.2018Lapse of the patent in a contracting state
New state(s): AL		published on 14.11.2018  [2018/46]
Applicant(s)For all designated states
Tokyo Women's Medical University
8-1 Kawada-cho Shinjuku-ku
Tokyo 162-8666 / JP
[2013/30]
Inventor(s)01 / SEKINE, Hidekazu
c/o Tokyo Women's Medical University
8-1 Kawada-cho
Shinjuku-ku
Tokyo 162-8666 / JP
02 / SHIMIZU, Tatsuya
c/o Tokyo Women's Medical University
8-1 Kawada-cho
Shinjuku-ku
Tokyo 162-8666 / JP
03 / OKANO, Teruo
c/o Tokyo Women's Medical University
8-1 Kawada-cho
Shinjuku-ku
Tokyo 162-8666 / JP
 [2013/30]
Representative(s)Krauns, Christian
Wallinger Ricker Schlotter Tostmann
Patent- und Rechtsanwälte Partnerschaft mbB
Zweibrückenstraße 5-7
80331 München / DE
[N/P]
Former [2013/30]Krauns, Christian
Wallinger Ricker Schlotter Tostmann
Patent- und Rechtsanwälte
Zweibrückenstraße 5-7
80331 München / DE
Application number, filing date11825224.614.09.2011
[2016/15]
WO2011JP71055
Priority number, dateJP2010022520014.09.2010         Original published format: JP 2010225200
[2013/30]
Filing languageJA
Procedural languageEN
PublicationType: A1 Application with search report
No.:WO2012036224
Date:22.03.2012
Language:JA
[2012/12]
Type: A1 Application with search report 
No.:EP2617810
Date:24.07.2013
Language:EN
[2013/30]
Type: B1 Patent specification 
No.:EP2617810
Date:13.04.2016
Language:EN
[2016/15]
Search report(s)International search report - published on:JP22.03.2012
(Supplementary) European search report - dispatched on:EP25.02.2014
ClassificationIPC:C12N5/071, A61L27/00, C12N5/077, C12N5/0775
[2013/30]
CPC:
A61K35/44 (EP,US); A61K35/34 (EP,US); A61K35/36 (EP,US);
A61L27/3604 (EP,US); A61L27/3839 (EP,US); A61L27/3895 (EP,US);
A61P9/00 (EP); A61P9/04 (EP); A61P9/10 (EP);
C12N5/0657 (EP,US); C12N2502/28 (EP,US); C12N2513/00 (EP,US) (-)
Designated contracting statesAL,   AT,   BE,   BG,   CH,   CY,   CZ,   DE,   DK,   EE,   ES,   FI,   FR,   GB,   GR,   HR,   HU,   IE,   IS,   IT,   LI,   LT,   LU,   LV,   MC,   MK,   MT,   NL,   NO,   PL,   PT,   RO,   RS,   SE,   SI,   SK,   SM,   TR [2013/30]
Extension statesBANot yet paid
MENot yet paid
TitleGerman:VERFAHREN ZUR HERSTELLUNG GESCHICHTETER ZELLSCHICHTEN, GESCHICHTETE ZELLSCHICHTEN MIT EINEM DADURCH GEWONNENEN GEFÄSSNETZ SOWIE VERFAHREN ZU IHRER VERWENDUNG[2013/30]
English:METHOD FOR PRODUCING LAYERED CELL SHEETS, LAYERED CELL SHEETS HAVING VASCULAR NETWORK OBTAINED THEREBY, AND METHOD FOR UTILIZING SAME[2013/30]
French:PROCÉDÉ DE PRODUCTION DE FEUILLETS DE CELLULES SUPERPOSÉES, FEUILLETS DE CELLULES SUPERPOSÉES DOTÉS D'UN RÉSEAU VASCULAIRE OBTENU PAR CE PROCÉDÉ, ET PROCÉDÉ D'UTILISATION ASSOCIÉ[2013/30]
Entry into regional phase10.04.2013Translation filed 
10.04.2013National basic fee paid 
10.04.2013Search fee paid 
10.04.2013Designation fee(s) paid 
10.04.2013Examination fee paid 
Examination procedure04.07.2012Request for preliminary examination filed
International Preliminary Examining Authority: JP
10.04.2013Examination requested  [2013/30]
12.09.2014Amendment by applicant (claims and/or description)
23.12.2014Despatch of a communication from the examining division (Time limit: M04)
30.04.2015Reply to a communication from the examining division
10.06.2015Despatch of a communication from the examining division (Time limit: M04)
19.10.2015Reply to a communication from the examining division
27.11.2015Communication of intention to grant the patent
17.02.2016Fee for grant paid
17.02.2016Fee for publishing/printing paid
17.02.2016Receipt of the translation of the claim(s)
Divisional application(s)The date of the Examining Division's first communication in respect of the earliest application for which a communication has been issued is  23.12.2014
Opposition(s)16.01.2017No opposition filed within time limit [2017/12]
Fees paidRenewal fee
22.08.2013Renewal fee patent year 03
29.09.2014Renewal fee patent year 04
29.09.2015Renewal fee patent year 05
Opt-out from the exclusive  Tooltip
competence of the Unified
Patent Court		 See the Register of the Unified Patent Court for opt-out data
Responsibility for the accuracy, completeness or quality of the data displayed under the link provided lies entirely with the Unified Patent Court.
Lapses during opposition  TooltipHU14.09.2011
AL13.04.2016
AT13.04.2016
BE13.04.2016
BG13.04.2016
CY13.04.2016
CZ13.04.2016
DK13.04.2016
EE13.04.2016
ES13.04.2016
FI13.04.2016
HR13.04.2016
IS13.04.2016
IT13.04.2016
LT13.04.2016
LV13.04.2016
MC13.04.2016
MK13.04.2016
NL13.04.2016
PL13.04.2016
RO13.04.2016
RS13.04.2016
SE13.04.2016
SI13.04.2016
SK13.04.2016
SM13.04.2016
TR13.04.2016
NO13.07.2016
GR14.07.2016
PT16.08.2016
IE14.09.2016
LU14.09.2016
CH30.09.2016
LI30.09.2016
MT30.09.2016
[2018/46]
Former [2018/38]HU14.09.2011
AT13.04.2016
BE13.04.2016
BG13.04.2016
CY13.04.2016
CZ13.04.2016
DK13.04.2016
EE13.04.2016
ES13.04.2016
FI13.04.2016
HR13.04.2016
IS13.04.2016
IT13.04.2016
LT13.04.2016
LV13.04.2016
MC13.04.2016
MK13.04.2016
NL13.04.2016
PL13.04.2016
RO13.04.2016
RS13.04.2016
SE13.04.2016
SI13.04.2016
SK13.04.2016
SM13.04.2016
TR13.04.2016
NO13.07.2016
GR14.07.2016
PT16.08.2016
IE14.09.2016
LU14.09.2016
CH30.09.2016
LI30.09.2016
MT30.09.2016
Former [2018/31]HU14.09.2011
AT13.04.2016
BE13.04.2016
CY13.04.2016
CZ13.04.2016
DK13.04.2016
EE13.04.2016
ES13.04.2016
FI13.04.2016
HR13.04.2016
IS13.04.2016
IT13.04.2016
LT13.04.2016
LV13.04.2016
MC13.04.2016
MK13.04.2016
NL13.04.2016
PL13.04.2016
RO13.04.2016
RS13.04.2016
SE13.04.2016
SI13.04.2016
SK13.04.2016
SM13.04.2016
TR13.04.2016
NO13.07.2016
GR14.07.2016
PT16.08.2016
IE14.09.2016
LU14.09.2016
CH30.09.2016
LI30.09.2016
MT30.09.2016
Former [2018/29]HU14.09.2011
AT13.04.2016
BE13.04.2016
CY13.04.2016
CZ13.04.2016
DK13.04.2016
EE13.04.2016
ES13.04.2016
FI13.04.2016
HR13.04.2016
IT13.04.2016
LT13.04.2016
LV13.04.2016
MC13.04.2016
MK13.04.2016
NL13.04.2016
PL13.04.2016
RO13.04.2016
RS13.04.2016
SE13.04.2016
SI13.04.2016
SK13.04.2016
SM13.04.2016
TR13.04.2016
NO13.07.2016
GR14.07.2016
PT16.08.2016
IE14.09.2016
LU14.09.2016
CH30.09.2016
LI30.09.2016
Former [2018/28]HU14.09.2011
AT13.04.2016
BE13.04.2016
CY13.04.2016
CZ13.04.2016
DK13.04.2016
EE13.04.2016
ES13.04.2016
FI13.04.2016
HR13.04.2016
IT13.04.2016
LT13.04.2016
LV13.04.2016
MC13.04.2016
MK13.04.2016
NL13.04.2016
PL13.04.2016
RO13.04.2016
RS13.04.2016
SE13.04.2016
SI13.04.2016
SK13.04.2016
SM13.04.2016
NO13.07.2016
GR14.07.2016
PT16.08.2016
IE14.09.2016
LU14.09.2016
CH30.09.2016
LI30.09.2016
Former [2017/41]AT13.04.2016
BE13.04.2016
CZ13.04.2016
DK13.04.2016
EE13.04.2016
ES13.04.2016
FI13.04.2016
HR13.04.2016
IT13.04.2016
LT13.04.2016
LV13.04.2016
MC13.04.2016
NL13.04.2016
PL13.04.2016
RO13.04.2016
RS13.04.2016
SE13.04.2016
SI13.04.2016
SK13.04.2016
SM13.04.2016
NO13.07.2016
GR14.07.2016
PT16.08.2016
IE14.09.2016
LU14.09.2016
CH30.09.2016
LI30.09.2016
Former [2017/37]AT13.04.2016
BE13.04.2016
CZ13.04.2016
DK13.04.2016
EE13.04.2016
ES13.04.2016
FI13.04.2016
HR13.04.2016
IT13.04.2016
LT13.04.2016
LV13.04.2016
MC13.04.2016
NL13.04.2016
PL13.04.2016
RO13.04.2016
RS13.04.2016
SE13.04.2016
SI13.04.2016
SK13.04.2016
SM13.04.2016
NO13.07.2016
GR14.07.2016
PT16.08.2016
IE14.09.2016
CH30.09.2016
LI30.09.2016
Former [2017/31]AT13.04.2016
BE13.04.2016
CZ13.04.2016
DK13.04.2016
EE13.04.2016
ES13.04.2016
FI13.04.2016
HR13.04.2016
IT13.04.2016
LT13.04.2016
LV13.04.2016
MC13.04.2016
NL13.04.2016
PL13.04.2016
RO13.04.2016
RS13.04.2016
SE13.04.2016
SI13.04.2016
SK13.04.2016
SM13.04.2016
NO13.07.2016
GR14.07.2016
PT16.08.2016
Former [2017/11]AT13.04.2016
BE13.04.2016
CZ13.04.2016
DK13.04.2016
EE13.04.2016
ES13.04.2016
FI13.04.2016
HR13.04.2016
IT13.04.2016
LT13.04.2016
LV13.04.2016
NL13.04.2016
PL13.04.2016
RO13.04.2016
RS13.04.2016
SE13.04.2016
SK13.04.2016
SM13.04.2016
NO13.07.2016
GR14.07.2016
PT16.08.2016
Former [2017/10]AT13.04.2016
BE13.04.2016
CZ13.04.2016
DK13.04.2016
EE13.04.2016
ES13.04.2016
FI13.04.2016
HR13.04.2016
IT13.04.2016
LT13.04.2016
LV13.04.2016
NL13.04.2016
PL13.04.2016
RO13.04.2016
RS13.04.2016
SE13.04.2016
SK13.04.2016
NO13.07.2016
GR14.07.2016
PT16.08.2016
Former [2017/09]AT13.04.2016
BE13.04.2016
CZ13.04.2016
DK13.04.2016
EE13.04.2016
ES13.04.2016
FI13.04.2016
HR13.04.2016
IT13.04.2016
LT13.04.2016
LV13.04.2016
NL13.04.2016
PL13.04.2016
RO13.04.2016
RS13.04.2016
SE13.04.2016
NO13.07.2016
GR14.07.2016
PT16.08.2016
Former [2017/07]AT13.04.2016
BE13.04.2016
DK13.04.2016
ES13.04.2016
FI13.04.2016
HR13.04.2016
IT13.04.2016
LT13.04.2016
LV13.04.2016
NL13.04.2016
PL13.04.2016
RS13.04.2016
SE13.04.2016
NO13.07.2016
GR14.07.2016
PT16.08.2016
Former [2017/03]AT13.04.2016
BE13.04.2016
ES13.04.2016
FI13.04.2016
HR13.04.2016
IT13.04.2016
LT13.04.2016
LV13.04.2016
NL13.04.2016
PL13.04.2016
RS13.04.2016
SE13.04.2016
NO13.07.2016
GR14.07.2016
PT16.08.2016
Former [2016/52]AT13.04.2016
ES13.04.2016
FI13.04.2016
HR13.04.2016
LT13.04.2016
LV13.04.2016
NL13.04.2016
PL13.04.2016
RS13.04.2016
SE13.04.2016
NO13.07.2016
GR14.07.2016
PT16.08.2016
Former [2016/51]AT13.04.2016
ES13.04.2016
FI13.04.2016
HR13.04.2016
LT13.04.2016
LV13.04.2016
NL13.04.2016
PL13.04.2016
RS13.04.2016
NO13.07.2016
GR14.07.2016
PT16.08.2016
Former [2016/50]AT13.04.2016
ES13.04.2016
FI13.04.2016
HR13.04.2016
LT13.04.2016
LV13.04.2016
NL13.04.2016
PL13.04.2016
RS13.04.2016
NO13.07.2016
Former [2016/49]FI13.04.2016
LT13.04.2016
NL13.04.2016
PL13.04.2016
NO13.07.2016
Former [2016/46]LT13.04.2016
NO13.07.2016
Documents cited:Search[A]WO2010065957  (TUFTS COLLEGE [US], et al) [A] 11-14 * chapter "System for Drug Discovery and Development" starting on page 31 * * paragraph bridging pages 18 and 19 *
 [XI]  - T. SHIMIZU, "Polysurgery of cell sheet grafts overcomes diffusion limits to produce thick, vascularized myocardial tissues", THE FASEB JOURNAL, (20060101), vol. 20, doi:10.1096/fj.05-4715fje, ISSN 0892-6638, pages 708 - 710, XP055082845 [X] 1,3-10 * figure 3 * * the whole document * [I] 2

DOI:   http://dx.doi.org/10.1096/fj.05-4715fje
International search[Y]JP2009531067  (NORTIS, INC.);
 [A]WO0208387  (OKANO TERUO [JP], et al)
 [X]  - SHIMIZU T. ET AL., "Polysurgery of cell sheet grafts overcomes diffusion limits to produce thick, vascularized myocardial tissues", FASEB J., (20060126), vol. 20, no. 6, pages 708 - 710, XP055082845

DOI:   http://dx.doi.org/10.1096/fj.05-4715fje
 [Y]  - SHINSUKE NOGUCHI ET AL., "Fabrication of 3-dimensional tissue using human cells", DAI 22 KAI PROCEEDINGS OF THE BIOENGINEERING CONFERENCE ANNUAL MEETING OF BE D/JSME, (201001), page 24
 [Y]  - KO SUGIBAYASHI ET AL., "Seibunkaisei Hydrogel Sonyu ni yoru Sekisoka Saibo Sheet eno Kanku Kozo no Sakusei", DAI 31 KAI THE ANNUAL MEETING OF THE JAPANESE SOCIETY FOR BIOMATERIALS, (2009), page 236
 [Y]  - SEKIYA S. ET AL., "Bioengineered cardiac cell sheet grafts have intrinsic angiogenic potential", BIOCHEM.BIOPHYS.RES.COMMUN., (2006), vol. 341, pages 573 - 582, XP024923910

DOI:   http://dx.doi.org/10.1016/j.bbrc.2005.12.217
 [A]  - SHIMIZU, T. ET AL., "Fabrication of pulsatilie cardiac tissue grafts using a novel 3-dimensional cell sheet manipulation technique and temperature -responsive cell culture surfaces", CIRCULATION RES., (2002), vol. 90, pages E40 - E48, XP002285777

DOI:   http://dx.doi.org/10.1161/hh0302.105722
by applicantJPH02211865
 JPH05192138
 WO0208387
    - FASEB. J., (2006), vol. 20, no. 6, pages 708 - 710
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