Extract from the Register of European Patents

EP About this file: EP2655309

EP2655309 - METHODS AND COMPOSITIONS FOR TREATING LUNG CANCER [Right-click to bookmark this link]
StatusThe application is deemed to be withdrawn
Status updated on  20.05.2016
Database last updated on 11.04.2026
Most recent event   Tooltip20.05.2016Application deemed to be withdrawnpublished on 22.06.2016  [2016/25]
Applicant(s)For all designated states
Golden Biotechnology Corporation
101 Hudson Street Suite 2100
Jersey City NJ 07302 / US
[2013/44]
Inventor(s)01 / LIU, Sheng-yung
15f, No 27-6
Sec 2
Jhong-jheng E. Rd.
Danshuei
New Taipei City / TW
02 / HWANG, San-bao
15f, No 27-6
Sec 2
Jhong-jheng E. Rd.
Danshuel
New Taipei City / TW
03 / WEN, Wu-che
15f, No 27-6
Sec 2
Jhong-jheng E. Rd.
Danshuei
New Taipei City / TW
 [2013/44]
Representative(s)Shah, Punita, et al
HGF Limited
4th Floor, Merchant Exchange
17-19 Whitworth Street West
Manchester M1 5WG / GB
[N/P]
Former [2014/07]Shah, Punita, et al
Harrison Goddard Foote LLP
4th Floor, Merchant Exchange
17-19 Whitworth Street West
Manchester M1 5WG / GB
Former [2013/44]Harrison Goddard Foote LLP
4th Floor
Merchant Exchange
17-19 Whitworth Street West
Manchester M1 5WG / GB
Application number, filing date11827110.515.04.2011
WO2011US32785
Priority number, dateUS20111307030823.03.2011         Original published format: US201113070308
TW2020914585324.12.2010         Original published format: TW 099145853
TW2020913184420.09.2010         Original published format: TW 099131844
[2013/44]
Filing languageEN
Procedural languageEN
PublicationType: A1 Application with search report
No.:WO2012039793
Date:29.03.2012
Language:EN
[2012/13]
Type: A1 Application with search report 
No.:EP2655309
Date:30.10.2013
Language:EN
The application published by WIPO in one of the EPO official languages on 29.03.2012 takes the place of the publication of the European patent application.
[2013/44]
Search report(s)International search report - published on:KR29.03.2012
(Supplementary) European search report - dispatched on:EP04.08.2014
ClassificationIPC:C07C49/517, C07C323/22, A61K31/122, A61K31/10, A61P35/00
[2013/44]
CPC:
C07H15/10 (EP,US); A61K31/122 (KR); A61P11/00 (EP);
A61P35/00 (EP,KR); A61P43/00 (EP); C07C323/22 (KR);
C07C403/02 (EP,US); C07C403/08 (EP,US); C07C403/10 (EP,US);
C07C403/20 (EP,US); C07C49/517 (KR); C07C2601/16 (EP,US) (-)
Designated contracting statesAL,   AT,   BE,   BG,   CH,   CY,   CZ,   DE,   DK,   EE,   ES,   FI,   FR,   GB,   GR,   HR,   HU,   IE,   IS,   IT,   LI,   LT,   LU,   LV,   MC,   MK,   MT,   NL,   NO,   PL,   PT,   RO,   RS,   SE,   SI,   SK,   SM,   TR [2013/44]
TitleGerman:VERFAHREN UND ZUSAMMENSETZUNGEN ZUR BEHANDLUNG VON LUNGENKREBS[2013/44]
English:METHODS AND COMPOSITIONS FOR TREATING LUNG CANCER[2013/44]
French:PROCÉDÉS ET COMPOSITIONS POUR TRAITER LE CANCER DU POUMON[2013/44]
Entry into regional phase18.04.2013National basic fee paid 
18.04.2013Search fee paid 
18.04.2013Designation fee(s) paid 
18.04.2013Examination fee paid 
Examination procedure18.04.2013Examination requested  [2013/44]
19.02.2015Amendment by applicant (claims and/or description)
07.07.2015Despatch of a communication from the examining division (Time limit: M06)
19.01.2016Application deemed to be withdrawn, date of legal effect  [2016/25]
15.02.2016Despatch of communication that the application is deemed to be withdrawn, reason: reply to the communication from the examining division not received in time  [2016/25]
Divisional application(s)The date of the Examining Division's first communication in respect of the earliest application for which a communication has been issued is  07.07.2015
Fees paidRenewal fee
18.04.2013Renewal fee patent year 03
13.10.2014Renewal fee patent year 04
10.04.2015Renewal fee patent year 05
Penalty fee
Additional fee for renewal fee
30.04.201404   M06   Fee paid on   13.10.2014
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Documents cited:Search[XI] US7342137  (LIU SHENG-YUN et al.) [X] 15 * Antroquinonol, the preferred compound of the present application, for use in the treatment of cancer: see column 2, lines 29-65; column 3, lines 5-15; examples, and claims *[I] 1-14
 [Y] US2007116787  (YAO CHIH-JUNG et al.) [Y] 1-15 * Extracts of Antrodia camphorata for use in the treatment of cancer, including lung cancer: see paragraphs 5, 10, 6, and claims 1, 4 *
 [XP] EP2233463  (GOLDEN BIOTECHNOLOGY CORP et al.) [XP] 1-11,13-15 * Compounds falling under the ones defined in claim 1 and their use for the treatment of lung cancer. See page 4,line 40; example 3, paragraph 29 and claims *
 [XP] WO2009052711  (GOLDEN BIOTECHNOLOGY CORP et al.) * the whole document *
 [X]   HSIEH WAN-YU ET AL: "Abstract #3676: Antroquinonol inhibits tumorgenesis and metastasis in highly invasive non-small-cell lung cancer cells", 21 April 2009 (2009-04-21), XP002726800, Retrieved from the Internet [retrieved on 20140620] [X] 1-15 * Antroquinonol inhibits cancer cell growth, cancer cell migration and invasion and selectively reduces cell survival signaling in the highly invasive lung adenocarcinoma cells. On the basis of this finding it is proposed as an anti-cancer drug for NSCLC treatment. *
 [XP]   V. BHARATH KUMAR ET AL: "Antroquinonol inhibits NSCLC proliferation by altering PI3K/mTOR proteins and miRNA expression profiles", MUTATION RESEARCH/FUNDAMENTAL AND MOLECULAR MECHANISMS OF MUTAGENESIS, vol. 707, no. 1-2, 24 December 2010 (2010-12-24), pages 42 - 52, XP055124441, ISSN: 0027-5107, DOI: 10.1016/j.mrfmmm.2010.12.009 [XP] 1-15 * Antroquinonol inhibits proliferation of Non Small Cell Lung Cancer (NSCLC) by inducing apoptosis in the cancer cells and is proposed for the treatment of lung cancer: see abstract, results and discussion and see conclusions in page 50 right hand column last paragraph and page 51 left hand column *

DOI:   http://dx.doi.org/10.1016/j.mrfmmm.2010.12.009
 [Y]   WU HUNG ET AL: "Proteomic analysis of the effect of Antrodia camphorata extract on human lung cancer A549 cell.", PROTEOMICS FEB 2006, vol. 6, no. 3, February 2006 (2006-02-01), pages 826 - 835, XP002726069, ISSN: 1615-9853 [Y] 1-15 * The extracts of Antrodia camphorata effectively inhibit the proliferation of NSCLC cells by inducing apoptosis of cancer cells. Antrodia camphorata is defined as a "potent herbal medicine in cancer related cases": see abstract, discussion figures and see page 833 first paragraph of the section "discussion" *

DOI:   http://dx.doi.org/10.1002/pmic.200401341
 [Y]   CHAN YU-YI ET AL: "Apoptotic effects of a high performance liquid chromatography (HPLC) fraction of Antrodia camphorata mycelia are mediated by down-regulation of the expressions of four tumor-related genes in human non-small cell lung carcinoma A549 cell.", JOURNAL OF ETHNOPHARMACOLOGY 17 FEB 2010, vol. 127, no. 3, 17 February 2010 (2010-02-17), pages 652 - 661, XP002726070, ISSN: 1872-7573 [Y] 1-15 * The extracts of Antrodia camphorata effectively inhibit the proliferation of NSCLC cells by inducing apoptosis of cancer cells: see abstract, discussion and figures *

DOI:   http://dx.doi.org/10.1016/j.jep.2009.12.008
International search[X] CN101225066  (GOLDEN BIOLOG TECHNOLOGY CO LT et al.) [X]
 [X] GB2453808  (GOLDEN BIOTECHNOLOGY CORP et al.) [X]
 [X]   LEE, TZONG-HUEI ET AL.: "A New Cytotoxic Agent from Solid-State Fermented Mycelium of Antrodia camphorata", PLANTA MEDICA, vol. 73, no. 13, 2007, pages 1412 - 1415, XP002626076 [X]

DOI:   http://dx.doi.org/10.1055/s-2007-990232
 [X]   YANG, SIEN-SING ET AL.: "New Constituents with iNOS Inhibitory Activity from Mycelium of Antrodia camphorata", PLANTA MEDICA, vol. 75, no. 5, 2009, pages 512 - 516, XP002626075 [X]

DOI:   http://dx.doi.org/10.1055/S-0029-1185305
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