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Extract from the Register of European Patents

EP About this file: EP2632949

EP2632949 - CLOSTRIDIUM DIFFICILE-SPECIFIC ANTIBODIES AND USES THEREOF [Right-click to bookmark this link]
StatusNo opposition filed within time limit
Status updated on  20.07.2018
Database last updated on 30.10.2024
FormerThe patent has been granted
Status updated on  11.08.2017
FormerGrant of patent is intended
Status updated on  04.08.2017
FormerExamination is in progress
Status updated on  19.07.2017
FormerGrant of patent is intended
Status updated on  07.03.2017
Most recent event   Tooltip17.07.2020Lapse of the patent in a contracting state
New state(s): AL		published on 19.08.2020  [2020/34]
Applicant(s)For all designated states
National Research Council of Canada
1200 Montreal Road
Ottawa, Ontario K1A 0R6 / CA
[2013/36]
Inventor(s)01 / HUSSACK, Greg
211 Ivy Crescent, Unit 5
Ottawa Ontario K1M 1X9 / CA
02 / ARBABI-GHAHROUDI, Mehdi
2242 Des Grands Champs
Ottawa Ontario K1W 1K1 / CA
03 / MACKENZIE, Roger
2195 Hamelin Crescent
Ottawa Ontario K1J 6K9 / CA
04 / TANHA, Jamshid
2162 Valin Street
Orleans Ontario K4A 4T2 / CA
 [2013/36]
Representative(s)Fleuchaus, Andrea, et al
Fleuchaus & Gallo Partnerschaft mbB
Patent- und Rechsanwälte
Steinerstraße 15/Haus A
81369 München / DE
[N/P]
Former [2017/37]Fleuchaus, Andrea, et al
Fleuchaus & Gallo Partnerschaft mbB
Patent- und Rechtsanwälte
Steinerstrasse 15/A
81369 München / DE
Former [2013/36]Fleuchaus, Andrea, et al
Fleuchaus & Gallo Partnerschaft
Patent- und Rechtsanwälte
Steinerstrasse 15/A
81369 München / DE
Application number, filing date11835397.825.10.2011
[2017/37]
WO2011CA01201
Priority number, dateUS20100406254P25.10.2010         Original published format: US 406254 P
[2013/36]
Filing languageEN
Procedural languageEN
PublicationType: A1 Application with search report
No.:WO2012055030
Date:03.05.2012
Language:EN
[2012/18]
Type: A1 Application with search report 
No.:EP2632949
Date:04.09.2013
Language:EN
The application published by WIPO in one of the EPO official languages on 03.05.2012 takes the place of the publication of the European patent application.
[2013/36]
Type: B1 Patent specification 
No.:EP2632949
Date:13.09.2017
Language:EN
[2017/37]
Search report(s)International search report - published on:CA03.05.2012
(Supplementary) European search report - dispatched on:EP22.06.2015
ClassificationIPC:C07K16/12, A61K39/395, G01N33/569
[2017/11]
CPC:
C07K16/1282 (EP,US); A61P31/04 (EP); G01N33/56911 (EP,US);
C07K2317/22 (EP,US); C07K2317/35 (EP,US); C07K2317/569 (EP,US);
C07K2317/76 (EP,US); C07K2317/92 (EP,US); C07K2317/94 (EP,US);
G01N2333/33 (EP,US) (-)
Former IPC [2013/36]C07K16/12, A61K39/395, A61K47/48, A61P31/04, C07K14/33, C07K17/00, C12N15/13, G01N33/53
Designated contracting statesAL,   AT,   BE,   BG,   CH,   CY,   CZ,   DE,   DK,   EE,   ES,   FI,   FR,   GB,   GR,   HR,   HU,   IE,   IS,   IT,   LI,   LT,   LU,   LV,   MC,   MK,   MT,   NL,   NO,   PL,   PT,   RO,   RS,   SE,   SI,   SK,   SM,   TR [2013/36]
Extension statesBANot yet paid
MENot yet paid
TitleGerman:CLOSTRIDIUM-DIFFICILE-SPEZIFISCHE ANTIKÖRPER UND VERWENDUNGEN DAVON[2013/36]
English:CLOSTRIDIUM DIFFICILE-SPECIFIC ANTIBODIES AND USES THEREOF[2013/36]
French:ANTICORPS SPÉCIFIQUES DE CLOSTRIDIUM DIFFICILE ET LEURS APPLICATIONS[2013/36]
Entry into regional phase27.05.2013National basic fee paid 
27.05.2013Search fee paid 
27.05.2013Designation fee(s) paid 
27.05.2013Examination fee paid 
Examination procedure27.05.2013Examination requested  [2013/36]
11.01.2016Amendment by applicant (claims and/or description)
20.06.2016Despatch of a communication from the examining division (Time limit: M04)
24.10.2016Reply to a communication from the examining division
08.03.2017Communication of intention to grant the patent
11.07.2017Disapproval of the communication of intention to grant the patent by the applicant or resumption of examination proceedings by the EPO
11.07.2017Fee for grant paid
11.07.2017Fee for publishing/printing paid
04.08.2017Information about intention to grant a patent
04.08.2017Receipt of the translation of the claim(s)
Divisional application(s)The date of the Examining Division's first communication in respect of the earliest application for which a communication has been issued is  20.06.2016
Opposition(s)14.06.2018No opposition filed within time limit [2018/34]
Fees paidRenewal fee
29.10.2013Renewal fee patent year 03
23.10.2014Renewal fee patent year 04
27.10.2015Renewal fee patent year 05
25.10.2016Renewal fee patent year 06
Opt-out from the exclusive  Tooltip
competence of the Unified
Patent Court		 See the Register of the Unified Patent Court for opt-out data
Responsibility for the accuracy, completeness or quality of the data displayed under the link provided lies entirely with the Unified Patent Court.
Lapses during opposition  TooltipHU25.10.2011
AL13.09.2017
AT13.09.2017
CY13.09.2017
CZ13.09.2017
DK13.09.2017
EE13.09.2017
ES13.09.2017
FI13.09.2017
HR13.09.2017
IT13.09.2017
LT13.09.2017
LV13.09.2017
MC13.09.2017
MK13.09.2017
NL13.09.2017
PL13.09.2017
PT13.09.2017
RO13.09.2017
RS13.09.2017
SE13.09.2017
SI13.09.2017
SK13.09.2017
SM13.09.2017
TR13.09.2017
IE25.10.2017
LU25.10.2017
MT25.10.2017
BE31.10.2017
CH31.10.2017
LI31.10.2017
BG13.12.2017
NO13.12.2017
GR14.12.2017
IS13.01.2018
[2020/34]
Former [2020/27]HU25.10.2011
AT13.09.2017
CY13.09.2017
CZ13.09.2017
DK13.09.2017
EE13.09.2017
ES13.09.2017
FI13.09.2017
HR13.09.2017
IT13.09.2017
LT13.09.2017
LV13.09.2017
MC13.09.2017
MK13.09.2017
NL13.09.2017
PL13.09.2017
PT13.09.2017
RO13.09.2017
RS13.09.2017
SE13.09.2017
SI13.09.2017
SK13.09.2017
SM13.09.2017
TR13.09.2017
IE25.10.2017
LU25.10.2017
MT25.10.2017
BE31.10.2017
CH31.10.2017
LI31.10.2017
BG13.12.2017
NO13.12.2017
GR14.12.2017
IS13.01.2018
Former [2020/16]HU25.10.2011
AT13.09.2017
CY13.09.2017
CZ13.09.2017
DK13.09.2017
EE13.09.2017
ES13.09.2017
FI13.09.2017
HR13.09.2017
IT13.09.2017
LT13.09.2017
LV13.09.2017
MC13.09.2017
MK13.09.2017
NL13.09.2017
PL13.09.2017
RO13.09.2017
RS13.09.2017
SE13.09.2017
SI13.09.2017
SK13.09.2017
SM13.09.2017
TR13.09.2017
IE25.10.2017
LU25.10.2017
MT25.10.2017
BE31.10.2017
CH31.10.2017
LI31.10.2017
BG13.12.2017
NO13.12.2017
GR14.12.2017
IS13.01.2018
Former [2019/51]HU25.10.2011
AT13.09.2017
CY13.09.2017
CZ13.09.2017
DK13.09.2017
EE13.09.2017
ES13.09.2017
FI13.09.2017
HR13.09.2017
IT13.09.2017
LT13.09.2017
LV13.09.2017
MC13.09.2017
MK13.09.2017
NL13.09.2017
PL13.09.2017
RO13.09.2017
RS13.09.2017
SE13.09.2017
SI13.09.2017
SK13.09.2017
SM13.09.2017
IE25.10.2017
LU25.10.2017
MT25.10.2017
BE31.10.2017
CH31.10.2017
LI31.10.2017
BG13.12.2017
NO13.12.2017
GR14.12.2017
IS13.01.2018
Former [2019/46]HU25.10.2011
AT13.09.2017
CY13.09.2017
CZ13.09.2017
DK13.09.2017
EE13.09.2017
ES13.09.2017
FI13.09.2017
HR13.09.2017
IT13.09.2017
LT13.09.2017
LV13.09.2017
MC13.09.2017
NL13.09.2017
PL13.09.2017
RO13.09.2017
RS13.09.2017
SE13.09.2017
SI13.09.2017
SK13.09.2017
SM13.09.2017
IE25.10.2017
LU25.10.2017
MT25.10.2017
BE31.10.2017
CH31.10.2017
LI31.10.2017
BG13.12.2017
NO13.12.2017
GR14.12.2017
IS13.01.2018
Former [2019/35]HU25.10.2011
AT13.09.2017
CZ13.09.2017
DK13.09.2017
EE13.09.2017
ES13.09.2017
FI13.09.2017
HR13.09.2017
IT13.09.2017
LT13.09.2017
LV13.09.2017
MC13.09.2017
NL13.09.2017
PL13.09.2017
RO13.09.2017
RS13.09.2017
SE13.09.2017
SI13.09.2017
SK13.09.2017
SM13.09.2017
IE25.10.2017
LU25.10.2017
MT25.10.2017
BE31.10.2017
CH31.10.2017
LI31.10.2017
BG13.12.2017
NO13.12.2017
GR14.12.2017
IS13.01.2018
Former [2019/31]HU25.10.2011
AT13.09.2017
CZ13.09.2017
DK13.09.2017
EE13.09.2017
FI13.09.2017
HR13.09.2017
IT13.09.2017
LT13.09.2017
LV13.09.2017
MC13.09.2017
NL13.09.2017
PL13.09.2017
RO13.09.2017
RS13.09.2017
SE13.09.2017
SI13.09.2017
SK13.09.2017
SM13.09.2017
IE25.10.2017
LU25.10.2017
MT25.10.2017
BE31.10.2017
CH31.10.2017
LI31.10.2017
BG13.12.2017
NO13.12.2017
GR14.12.2017
IS13.01.2018
Former [2018/52]AT13.09.2017
CZ13.09.2017
DK13.09.2017
EE13.09.2017
FI13.09.2017
HR13.09.2017
IT13.09.2017
LT13.09.2017
LV13.09.2017
MC13.09.2017
NL13.09.2017
PL13.09.2017
RO13.09.2017
RS13.09.2017
SE13.09.2017
SI13.09.2017
SK13.09.2017
SM13.09.2017
IE25.10.2017
LU25.10.2017
MT25.10.2017
BE31.10.2017
CH31.10.2017
LI31.10.2017
BG13.12.2017
NO13.12.2017
GR14.12.2017
IS13.01.2018
Former [2018/45]AT13.09.2017
CZ13.09.2017
DK13.09.2017
EE13.09.2017
FI13.09.2017
HR13.09.2017
IT13.09.2017
LT13.09.2017
LV13.09.2017
MC13.09.2017
NL13.09.2017
PL13.09.2017
RO13.09.2017
RS13.09.2017
SE13.09.2017
SK13.09.2017
SM13.09.2017
IE25.10.2017
LU25.10.2017
MT25.10.2017
BE31.10.2017
CH31.10.2017
LI31.10.2017
BG13.12.2017
NO13.12.2017
GR14.12.2017
IS13.01.2018
Former [2018/43]AT13.09.2017
CZ13.09.2017
DK13.09.2017
EE13.09.2017
FI13.09.2017
HR13.09.2017
IT13.09.2017
LT13.09.2017
LV13.09.2017
MC13.09.2017
NL13.09.2017
PL13.09.2017
RO13.09.2017
RS13.09.2017
SE13.09.2017
SK13.09.2017
SM13.09.2017
LU25.10.2017
MT25.10.2017
BE31.10.2017
CH31.10.2017
LI31.10.2017
BG13.12.2017
NO13.12.2017
GR14.12.2017
IS13.01.2018
Former [2018/36]AT13.09.2017
CZ13.09.2017
DK13.09.2017
EE13.09.2017
FI13.09.2017
HR13.09.2017
IT13.09.2017
LT13.09.2017
LV13.09.2017
MC13.09.2017
NL13.09.2017
PL13.09.2017
RO13.09.2017
RS13.09.2017
SE13.09.2017
SK13.09.2017
SM13.09.2017
LU25.10.2017
BE31.10.2017
CH31.10.2017
LI31.10.2017
BG13.12.2017
NO13.12.2017
GR14.12.2017
IS13.01.2018
Former [2018/35]AT13.09.2017
CZ13.09.2017
DK13.09.2017
EE13.09.2017
FI13.09.2017
HR13.09.2017
IT13.09.2017
LT13.09.2017
LV13.09.2017
MC13.09.2017
NL13.09.2017
PL13.09.2017
RO13.09.2017
RS13.09.2017
SE13.09.2017
SK13.09.2017
SM13.09.2017
LU25.10.2017
CH31.10.2017
LI31.10.2017
BG13.12.2017
NO13.12.2017
GR14.12.2017
IS13.01.2018
Former [2018/33]AT13.09.2017
CZ13.09.2017
DK13.09.2017
EE13.09.2017
FI13.09.2017
HR13.09.2017
IT13.09.2017
LT13.09.2017
LV13.09.2017
MC13.09.2017
NL13.09.2017
PL13.09.2017
RO13.09.2017
RS13.09.2017
SE13.09.2017
SK13.09.2017
SM13.09.2017
CH31.10.2017
LI31.10.2017
BG13.12.2017
NO13.12.2017
GR14.12.2017
IS13.01.2018
Former [2018/24]AT13.09.2017
CZ13.09.2017
EE13.09.2017
FI13.09.2017
HR13.09.2017
IT13.09.2017
LT13.09.2017
LV13.09.2017
NL13.09.2017
PL13.09.2017
RO13.09.2017
RS13.09.2017
SE13.09.2017
SK13.09.2017
SM13.09.2017
BG13.12.2017
NO13.12.2017
GR14.12.2017
IS13.01.2018
Former [2018/23]AT13.09.2017
CZ13.09.2017
EE13.09.2017
FI13.09.2017
HR13.09.2017
LT13.09.2017
LV13.09.2017
NL13.09.2017
PL13.09.2017
RO13.09.2017
RS13.09.2017
SE13.09.2017
SK13.09.2017
BG13.12.2017
NO13.12.2017
GR14.12.2017
IS13.01.2018
Former [2018/21]CZ13.09.2017
FI13.09.2017
HR13.09.2017
LT13.09.2017
LV13.09.2017
NL13.09.2017
RS13.09.2017
SE13.09.2017
BG13.12.2017
NO13.12.2017
GR14.12.2017
Former [2018/15]FI13.09.2017
HR13.09.2017
LT13.09.2017
LV13.09.2017
NL13.09.2017
RS13.09.2017
SE13.09.2017
BG13.12.2017
NO13.12.2017
GR14.12.2017
Former [2018/12]FI13.09.2017
HR13.09.2017
LT13.09.2017
LV13.09.2017
RS13.09.2017
SE13.09.2017
BG13.12.2017
NO13.12.2017
GR14.12.2017
Former [2018/11]FI13.09.2017
HR13.09.2017
LT13.09.2017
RS13.09.2017
SE13.09.2017
BG13.12.2017
NO13.12.2017
GR14.12.2017
Former [2018/09]FI13.09.2017
LT13.09.2017
SE13.09.2017
NO13.12.2017
Former [2018/08]FI13.09.2017
LT13.09.2017
NO13.12.2017
Former [2018/07]LT13.09.2017
NO13.12.2017
Documents cited:Search[YA]WO2006099747  (CA NAT RESEARCH COUNCIL [CA], et al) [Y] 4-17 * page 1, line 10 - page 2, line 29 * [A] 1-3;
 [YA]  - BABCOCK GREGORY J ET AL, "Human monoclonal antibodies directed against toxins A and B prevent Clostridium difficile-induced mortality in hamsters", INFECTION AND IMMUNITY, AMERICAN SOCIETY FOR MICROBIOLOGY, US, (20061101), vol. 74, no. 11, doi:10.1128/IAI.00982-06, ISSN 0019-9567, pages 6339 - 6347, XP009109025 [Y] 4-17 * abstract * * RESULTS: 'Isolation of human monoclonal antibodies directed against Clostridium difficile toxins A and B', 'Antitoxin HuMAbs protect hamsters from mortality associated with C. difficile disease' * * DISCUSSION * [A] 1-3

DOI:   http://dx.doi.org/10.1128/IAI.00982-06
International search[A]  - HUSSACK G. ET AL., "Toxin-specific antibodies for the treatment of Clostridium difficile: current status and future perspectives", TOXINS, (2010), vol. 2, no. 5, pages 998 - 1018, XP002692188

DOI:   http://dx.doi.org/10.3390/toxins2050998
 [A]  - BABCOCK G.J. ET AL., "Human monoclonal antibodies directed against toxins A and B prevent Clostridium difficile-induced mortality in hamsters", INFECTION AND IMMUNITY, (200611), vol. 74, no. 11, pages 6339 - 6347, XP009109025

DOI:   http://dx.doi.org/10.1128/IAI.00982-06
 [XP]  - HUSSACK G. ET AL., "Neutralization of Clostridium difficile toxin A with single- domain antibodies targeting the cell receptor binding domain", JOURNAL OF BIOLOGICAL CHEMISTRY, (20110107), vol. 286, no. 11, pages 8961 - 8976, XP002692187

DOI:   http://dx.doi.org/10.1074/jbc.M110.198754
Examination   - GREG HUSSACK AND JAMSHID TANHA, "Toxin-Specific Antibodies for the Treatment of Clostridium difficile: Current Status and Future Perspectives", TOXINS, MOLECULAR DIVERSITY PRESERVATION INTERNATIONAL (MDPI) AG, CH, vol. 2, no. 5, doi:10.3390/TOXINS2050998, ISSN 2072-6651, (20100501), pages 998 - 1018, (20100507), XP002686777

DOI:   http://dx.doi.org/10.3390/toxins2050998
by applicantUS6180370
 US5693761
 US6054297
 US5859205
 EP0626390
 US5869619
 US5766886
 US5821123
 EP0519596
 WO9504069
 WO2004076670
 WO03046560
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