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Extract from the Register of European Patents

EP About this file: EP2655365

EP2655365 - 2-CARBOXAMIDE-4-PIPERAZINYL-BENZOFURAN DERIVATIVE [Right-click to bookmark this link]
StatusNo opposition filed within time limit
Status updated on  21.10.2016
Database last updated on 31.08.2024
Most recent event   Tooltip12.10.2018Lapse of the patent in a contracting state
New state(s): AL		published on 14.11.2018  [2018/46]
Applicant(s)For all designated states
Acturum Life Science AB
P.O. Box 808
169 28 Solna / SE
[2015/20]
Former [2013/44]For all designated states
AstraZeneca AB
151 85 Södertälje / SE
Inventor(s)01 / GYBÄCK, Helena
c/o AstraZeneca RIntellectual Property
AstraZeneca R&D Alderley
Alderley Park
Macclesfield, Cheshire SK10 4TG / GB
02 / MALMSTRÖM, Jonas
c/o AstraZeneca RIntellectual Property
AstraZeneca R&D Alderley
Alderley Park
Macclesfield, Cheshire SK10 4TG / GB
03 / TERP, Elgaard, Gitte
c/o AstraZeneca RIntellectual Property
AstraZeneca R&D Alderley
Alderley Park
Macclesfield, Cheshire SK10 4TG / GB
 [2013/44]
Representative(s)Neelissen-Subnel, Marianne
Swea IP Law AB
Forskargatan 20G
151 36 Södertälje / SE
[N/P]
Former [2015/51]Neelissen-Subnel, Marianne
Swea IP Law AB
Box 44
151 21 Södertälje / SE
Former [2014/33]Neelissen-Subnel, Marianne
NELLPAT
P.O.Box 138
683 23 Hagfors / SE
Former [2014/17]Neelissen-Subnel, Marianne, et al
Swea IP Law AB
Kopparbergsvägen 6
722 13 Västerås / SE
Former [2013/44]Verboom, Renzo Christiaan
Zacco Sweden AB
P.O. Box 5581
114 85 Stockholm / SE
Application number, filing date11850834.019.12.2011
[2015/51]
WO2011SE51535
Priority number, dateUS201061424944P20.12.2010         Original published format: US 201061424944 P
[2013/44]
Filing languageEN
Procedural languageEN
PublicationType: A1 Application with search report
No.:WO2012087229
Date:28.06.2012
Language:EN
[2012/26]
Type: A1 Application with search report 
No.:EP2655365
Date:30.10.2013
Language:EN
The application published by WIPO in one of the EPO official languages on 28.06.2012 takes the place of the publication of the European patent application.
[2013/44]
Type: B1 Patent specification 
No.:EP2655365
Date:16.12.2015
Language:EN
[2015/51]
Search report(s)International search report - published on:SE28.06.2012
(Supplementary) European search report - dispatched on:EP10.07.2014
ClassificationIPC:C07D405/12, A61K31/4709, A61P25/00, A61P25/24, A61P25/28, C07D215/227, C07D307/85
[2014/33]
CPC:
C07D405/12 (EP,US); C07D405/14 (KR); A61K31/497 (KR);
A61P21/00 (EP); A61P21/02 (EP); A61P21/04 (EP);
A61P25/00 (EP); A61P25/02 (EP); A61P25/14 (EP);
A61P25/16 (EP); A61P25/18 (EP); A61P25/24 (EP);
A61P25/28 (EP); A61P43/00 (EP); C07D215/227 (EP,US);
C07D307/85 (EP,US) (-)
Former IPC [2013/44]C07D405/12, A61K31/4709, A61P25/00, A61P25/24, A61P25/28
Designated contracting statesAL,   AT,   BE,   BG,   CH,   CY,   CZ,   DE,   DK,   EE,   ES,   FI,   FR,   GB,   GR,   HR,   HU,   IE,   IS,   IT,   LI,   LT,   LU,   LV,   MC,   MK,   MT,   NL,   NO,   PL,   PT,   RO,   RS,   SE,   SI,   SK,   SM,   TR [2013/44]
Extension statesBANot yet paid
MENot yet paid
TitleGerman:2-CARBOXAMID-4-PIPERAZINYL-BENZOFURAN-DERIVAT[2013/44]
English:2-CARBOXAMIDE-4-PIPERAZINYL-BENZOFURAN DERIVATIVE[2013/44]
French:DÉRIVÉ DE 2-CARBOXAMIDE-4-PIPÉRAZINYL-BENZOFURANE[2013/44]
Entry into regional phase12.06.2013National basic fee paid 
12.06.2013Search fee paid 
12.06.2013Designation fee(s) paid 
12.06.2013Examination fee paid 
Examination procedure12.06.2013Examination requested  [2013/44]
26.03.2015Despatch of communication that the application is deemed to be withdrawn, reason: reply to the Extended European Search Report/Written Opinion of the International Searching Authority/International Preliminary Examination Report/Supplementary international search report not received in time
01.04.2015Amendment by applicant (claims and/or description)
09.07.2015Communication of intention to grant the patent
20.10.2015Fee for grant paid
20.10.2015Fee for publishing/printing paid
22.10.2015Receipt of the translation of the claim(s)
Divisional application(s)The date of the Examining Division's first communication in respect of the earliest application for which a communication has been issued is  09.07.2015
Opposition(s)19.09.2016No opposition filed within time limit [2016/47]
Request for further processing for:The application is deemed to be withdrawn due to failure to reply to the Extended European Search Report/Written Opinion of the International Searching Authority/International Preliminary Examination Report/Supplementary international search report/Supplementary European search report
01.04.2015Request for further processing filed
01.04.2015Full payment received (date of receipt of payment)
Request granted
17.04.2015Decision despatched
Fees paidRenewal fee
12.12.2013Renewal fee patent year 03
30.12.2014Renewal fee patent year 04
Opt-out from the exclusive  Tooltip
competence of the Unified
Patent Court		 See the Register of the Unified Patent Court for opt-out data
Responsibility for the accuracy, completeness or quality of the data displayed under the link provided lies entirely with the Unified Patent Court.
Lapses during opposition  TooltipHU19.12.2011
AL16.12.2015
AT16.12.2015
BE16.12.2015
BG16.12.2015
CY16.12.2015
CZ16.12.2015
DK16.12.2015
EE16.12.2015
ES16.12.2015
FI16.12.2015
HR16.12.2015
LT16.12.2015
LV16.12.2015
MC16.12.2015
MK16.12.2015
MT16.12.2015
NL16.12.2015
PL16.12.2015
RO16.12.2015
RS16.12.2015
SI16.12.2015
SK16.12.2015
SM16.12.2015
TR16.12.2015
IE19.12.2015
LU19.12.2015
NO16.03.2016
GR17.03.2016
IS16.04.2016
PT18.04.2016
[2018/46]
Former [2018/45]HU19.12.2011
AT16.12.2015
BE16.12.2015
BG16.12.2015
CY16.12.2015
CZ16.12.2015
DK16.12.2015
EE16.12.2015
ES16.12.2015
FI16.12.2015
HR16.12.2015
LT16.12.2015
LV16.12.2015
MC16.12.2015
MK16.12.2015
MT16.12.2015
NL16.12.2015
PL16.12.2015
RO16.12.2015
RS16.12.2015
SI16.12.2015
SK16.12.2015
SM16.12.2015
TR16.12.2015
IE19.12.2015
LU19.12.2015
NO16.03.2016
GR17.03.2016
IS16.04.2016
PT18.04.2016
Former [2018/31]HU19.12.2011
AT16.12.2015
BE16.12.2015
BG16.12.2015
CY16.12.2015
CZ16.12.2015
DK16.12.2015
EE16.12.2015
ES16.12.2015
FI16.12.2015
HR16.12.2015
LT16.12.2015
LV16.12.2015
MC16.12.2015
MK16.12.2015
MT16.12.2015
NL16.12.2015
PL16.12.2015
RO16.12.2015
RS16.12.2015
SI16.12.2015
SK16.12.2015
SM16.12.2015
IE19.12.2015
LU19.12.2015
NO16.03.2016
GR17.03.2016
IS16.04.2016
PT18.04.2016
Former [2018/02]HU19.12.2011
AT16.12.2015
BE16.12.2015
BG16.12.2015
CY16.12.2015
CZ16.12.2015
DK16.12.2015
EE16.12.2015
ES16.12.2015
FI16.12.2015
HR16.12.2015
LT16.12.2015
LV16.12.2015
MC16.12.2015
MT16.12.2015
NL16.12.2015
PL16.12.2015
RO16.12.2015
RS16.12.2015
SI16.12.2015
SK16.12.2015
SM16.12.2015
IE19.12.2015
LU19.12.2015
NO16.03.2016
GR17.03.2016
IS16.04.2016
PT18.04.2016
Former [2017/39]HU19.12.2011
AT16.12.2015
BE16.12.2015
BG16.12.2015
CY16.12.2015
CZ16.12.2015
DK16.12.2015
EE16.12.2015
ES16.12.2015
FI16.12.2015
HR16.12.2015
LT16.12.2015
LV16.12.2015
MC16.12.2015
MT16.12.2015
NL16.12.2015
PL16.12.2015
RO16.12.2015
RS16.12.2015
SI16.12.2015
SK16.12.2015
SM16.12.2015
IE19.12.2015
NO16.03.2016
GR17.03.2016
IS16.04.2016
PT18.04.2016
Former [2017/16]AT16.12.2015
BE16.12.2015
CZ16.12.2015
DK16.12.2015
EE16.12.2015
ES16.12.2015
FI16.12.2015
HR16.12.2015
LT16.12.2015
LV16.12.2015
MC16.12.2015
NL16.12.2015
PL16.12.2015
RO16.12.2015
RS16.12.2015
SI16.12.2015
SK16.12.2015
SM16.12.2015
IE19.12.2015
NO16.03.2016
GR17.03.2016
IS16.04.2016
PT18.04.2016
Former [2017/03]AT16.12.2015
BE16.12.2015
CZ16.12.2015
DK16.12.2015
EE16.12.2015
ES16.12.2015
FI16.12.2015
HR16.12.2015
LT16.12.2015
LV16.12.2015
MC16.12.2015
NL16.12.2015
PL16.12.2015
RO16.12.2015
RS16.12.2015
SK16.12.2015
SM16.12.2015
IE19.12.2015
NO16.03.2016
GR17.03.2016
IS16.04.2016
PT18.04.2016
Former [2016/49]AT16.12.2015
CZ16.12.2015
DK16.12.2015
EE16.12.2015
ES16.12.2015
FI16.12.2015
HR16.12.2015
LT16.12.2015
LV16.12.2015
MC16.12.2015
NL16.12.2015
PL16.12.2015
RO16.12.2015
RS16.12.2015
SK16.12.2015
SM16.12.2015
IE19.12.2015
BE31.12.2015
NO16.03.2016
GR17.03.2016
IS16.04.2016
PT18.04.2016
Former [2016/46]AT16.12.2015
CZ16.12.2015
DK16.12.2015
EE16.12.2015
ES16.12.2015
FI16.12.2015
HR16.12.2015
LT16.12.2015
LV16.12.2015
MC16.12.2015
NL16.12.2015
RO16.12.2015
RS16.12.2015
SK16.12.2015
SM16.12.2015
IE19.12.2015
BE31.12.2015
NO16.03.2016
GR17.03.2016
IS16.04.2016
PT18.04.2016
Former [2016/45]AT16.12.2015
CZ16.12.2015
EE16.12.2015
ES16.12.2015
FI16.12.2015
HR16.12.2015
LT16.12.2015
LV16.12.2015
MC16.12.2015
NL16.12.2015
RO16.12.2015
RS16.12.2015
SK16.12.2015
SM16.12.2015
IE19.12.2015
BE31.12.2015
NO16.03.2016
GR17.03.2016
IS16.04.2016
PT18.04.2016
Former [2016/42]AT16.12.2015
CZ16.12.2015
EE16.12.2015
ES16.12.2015
FI16.12.2015
HR16.12.2015
LT16.12.2015
LV16.12.2015
MC16.12.2015
NL16.12.2015
RO16.12.2015
RS16.12.2015
SK16.12.2015
SM16.12.2015
BE31.12.2015
NO16.03.2016
GR17.03.2016
IS16.04.2016
PT18.04.2016
Former [2016/38]AT16.12.2015
CZ16.12.2015
EE16.12.2015
ES16.12.2015
FI16.12.2015
HR16.12.2015
LT16.12.2015
LV16.12.2015
NL16.12.2015
RO16.12.2015
RS16.12.2015
SK16.12.2015
SM16.12.2015
BE31.12.2015
NO16.03.2016
GR17.03.2016
IS16.04.2016
PT18.04.2016
Former [2016/36]AT16.12.2015
CZ16.12.2015
EE16.12.2015
ES16.12.2015
FI16.12.2015
HR16.12.2015
LT16.12.2015
LV16.12.2015
NL16.12.2015
RO16.12.2015
RS16.12.2015
SK16.12.2015
BE31.12.2015
NO16.03.2016
GR17.03.2016
Former [2016/35]CZ16.12.2015
ES16.12.2015
FI16.12.2015
HR16.12.2015
LT16.12.2015
LV16.12.2015
NL16.12.2015
RS16.12.2015
BE31.12.2015
NO16.03.2016
GR17.03.2016
Former [2016/34]CZ16.12.2015
FI16.12.2015
HR16.12.2015
LT16.12.2015
LV16.12.2015
NL16.12.2015
RS16.12.2015
BE31.12.2015
NO16.03.2016
GR17.03.2016
Former [2016/26]FI16.12.2015
HR16.12.2015
LT16.12.2015
LV16.12.2015
NL16.12.2015
RS16.12.2015
BE31.12.2015
NO16.03.2016
GR17.03.2016
Former [2016/25]FI16.12.2015
HR16.12.2015
LT16.12.2015
LV16.12.2015
RS16.12.2015
BE31.12.2015
NO16.03.2016
GR17.03.2016
Former [2016/24]FI16.12.2015
HR16.12.2015
LT16.12.2015
RS16.12.2015
BE31.12.2015
NO16.03.2016
GR17.03.2016
Former [2016/23]HR16.12.2015
LT16.12.2015
RS16.12.2015
NO16.03.2016
Former [2016/21]LT16.12.2015
NO16.03.2016
Former [2016/20]LT16.12.2015
Documents cited:Search[IA]US2006160824  (HEINRICH TIMO [DE], et al) [I] 8,9 * page 4, paragraph 81 - page 5, paragraph 82 * * claims 1-14 * [A] 1-7,10,11;
 [IA]WO2008037681  (GLAXO GROUP LTD [GB], et al) [I] 10,11 * claims 1-25 * * page 14, line 7 - line 31 * [A] 1-9;
 [IA]  - BROMIDGE S M ET AL, "5-{2-[4-(2-Methyl-5-quinolinyl)-1-piperazinyl]ethyl}-2(1H)-quinolinones and 3,4-dihydro-2(1H)-quinolinones: Dual-acting 5-HT1 receptor antagonists and serotonin reuptake inhibitors. Part 3", BIOORGANIC & MEDICINAL CHEMISTRY LETTERS, PERGAMON, AMSTERDAM, NL, vol. 20, no. 23, doi:10.1016/J.BMCL.2010.09.085, ISSN 0960-894X, (20101201), pages 7092 - 7096, (20100927), XP027459364 [I] 10,11 * abstract * * page 7055; table 2; compound 11 * [A] 1-9

DOI:   http://dx.doi.org/10.1016/j.bmcl.2010.09.085
 [IA]  - HEINRICH T ET AL, "Synthesis and Structure-Activity Relationship in a Class of Indolebutylpiperazines as Dual 5-HT1A Receptor Agonists and Serotonin Reuptake Inhibitors", JOURNAL OF MEDICINAL CHEMISTRY, AMERICAN CHEMICAL SOCIETY, US, (20040101), vol. 47, no. 19, doi:10.1021/JM040793Q, ISSN 0022-2623, pages 4684 - 4692, XP002388367 [I] 8,9 * abstract * * table 2; compounds 28-29 * [A] 1-7,10,11

DOI:   http://dx.doi.org/10.1021/jm040793q
International search[A]US4782061  (KRUSE CORNELIS G [NL], et al);
 [A]WO0216354  (MERCK PATENT GMBH [DE], et al);
 [A]WO9406789  (MERRELL DOW PHARMA [US])
by applicant   - BARNES; SHARP, NEUROPHARMACOLOGY, (1999), vol. 38, pages 1083 - 1152
The EPO accepts no responsibility for the accuracy of data originating from other authorities; in particular, it does not guarantee that it is complete, up to date or fit for specific purposes.