-
EP2491993
European procedure
Extract from the Register of European Patents
EP About this file: EP2491993
| EP2491993 - Methods for separating compounds [Right-click to bookmark this link] | Status | Patent revoked Status updated on 28.10.2022 Database last updated on 18.11.2024 | |
| Former | The patent has been granted Status updated on 31.08.2018 | ||
| Former | Grant of patent is intended Status updated on 17.04.2018 | ||
| Former | Examination is in progress Status updated on 15.11.2016 | Most recent event Tooltip | 28.10.2022 | Revocation of patent | published on 30.11.2022 [2022/48] | Applicant(s) | For all designated states Waters Technologies Corporation 34 Maple Street Milford, MA 01757 / US | [2018/40] |
| Former [2012/35] | For all designated states Waters Technologies Corporation 34 Maple Street Milford, MA 01757 / US | Inventor(s) | 01 /
Gilar, Martin 38 Palomino Drive Franklin, Massachussets 02038 / US | 02 /
Neue, Uwe D. 20 Donny Lee Lane Ashland, Massassuchets 01721 / US | [2012/35] | Representative(s) | Forresters IP LLP Skygarden Erika-Mann-Straße 11 80636 München / DE | [N/P] |
| Former [2018/40] | Harding, Andrew Philip, et al Forresters IP LLP Skygarden Erika-Mann-Strasse 11 80636 München / DE | ||
| Former [2012/35] | Müller, Christian Stefan Gerd, et al Dr. Volker Vossius Patent- und Rechtsanwaltskanzlei Geibelstrasse 6 81679 München / DE | Application number, filing date | 12004053.0 | 20.01.2006 | [2012/35] | Priority number, date | US20050645810P | 20.01.2005 Original published format: US 645810 P | US20050655840P | 23.02.2005 Original published format: US 655840 P | US20050686268P | 31.05.2005 Original published format: US 686268 P | [2012/35] | Filing language | EN | Procedural language | EN | Publication | Type: | A1 Application with search report | No.: | EP2491993 | Date: | 29.08.2012 | Language: | EN | [2012/35] | Type: | B1 Patent specification | No.: | EP2491993 | Date: | 03.10.2018 | Language: | EN | [2018/40] | Search report(s) | (Supplementary) European search report - dispatched on: | EP | 17.07.2012 | Classification | IPC: | B01D15/18, B01D15/32 | [2018/15] | CPC: |
B01D15/325 (EP,US);
B01D15/1878 (EP,US);
B01D15/305 (EP);
G01N30/02 (EP,US);
G01N30/461 (EP,US);
G01N30/463 (EP,US)
| C-Set: |
B01D15/305, B01D15/305 (EP);
B01D15/325, B01D15/325 (EP);
G01N30/02, B01D15/3861 (EP,US);
G01N30/461, B01D15/325, B01D15/325 (US,EP); |
| Former IPC [2012/35] | B01D15/08 | Designated contracting states | DE, FR, GB [2018/40] |
| Former [2012/35] | DE, FR, GB | Title | German: | Verfahren zur Trennung von Verbindungen | [2012/35] | English: | Methods for separating compounds | [2012/35] | French: | Procédés de séparation de composés | [2012/35] | Examination procedure | 28.02.2013 | Amendment by applicant (claims and/or description) | 28.02.2013 | Examination requested [2013/15] | 25.02.2014 | Despatch of a communication from the examining division (Time limit: M04) | 01.07.2014 | Reply to a communication from the examining division | 12.03.2015 | Despatch of a communication from the examining division (Time limit: M06) | 01.09.2015 | Reply to a communication from the examining division | 11.07.2016 | Despatch of a communication from the examining division (Time limit: M04) | 24.10.2016 | Observations by third parties | 14.11.2016 | Reply to a communication from the examining division | 08.02.2017 | Despatch of a communication from the examining division (Time limit: M04) | 16.06.2017 | Reply to a communication from the examining division | 23.08.2017 | Despatch of a communication from the examining division (Time limit: M04) | 27.12.2017 | Reply to a communication from the examining division | 18.04.2018 | Communication of intention to grant the patent | 24.08.2018 | Fee for grant paid | 24.08.2018 | Fee for publishing/printing paid | 24.08.2018 | Receipt of the translation of the claim(s) | Parent application(s) Tooltip | EP06718965.4 / EP1871503 | Divisional application(s) | EP15168031.1 / EP2937126 | EP21162750.0 / EP3885018 | The date of the Examining Division's first communication in respect of the earliest application for which a communication has been issued (EP20060718965) is 31.05.2010 | Opposition(s) | Opponent(s) | 01
02.07.2019
ADMISSIBLE Agilent Technologies, Inc. -a Delaware Corporation- 5301 Stevens Creek Blvd. Santa Clara CA 95051 / US Opponent's representative Dilg, Haeusler, Schindelmann Patentanwaltsgesellschaft mbH Leonrodstraße 58 80636 München / DE | [N/P] |
| Former [2019/32] | |||
| Opponent(s) | 01
02.07.2019
ADMISSIBLE Agilent Technologies, Inc. -a Delaware Corporation- 5301 Stevens Creek Blvd. Santa Clara CA 95051 / US Opponent's representative Dilg, Haeusler, Schindelmann Patentanwaltsgesellschaft mbH Leonrodstrasse 58 80636 München / DE | 17.07.2019 | Invitation to proprietor to file observations on the notice of opposition | 27.11.2019 | Reply of patent proprietor to notice(s) of opposition | 19.08.2020 | Cancellation of oral proceeding that was planned for 15.10.2020 | 15.10.2020 | Date of oral proceedings | 15.03.2021 | Date of oral proceedings | 08.04.2021 | Despatch of minutes of oral proceedings | 08.04.2021 | Despatch of communication that the patent will be revoked | 21.10.2022 | Legal effect of revocation of patent [2022/48] | Appeal following opposition | 07.06.2021 | Appeal received No. T0751/21 | 07.06.2021 | Payment of appeal fee | 28.07.2021 | Statement of grounds filed | 21.10.2022 | Result of appeal procedure: appeal of the proprietor withdrawn | Fees paid | Renewal fee | 24.05.2012 | Renewal fee patent year 03 | 24.05.2012 | Renewal fee patent year 04 | 24.05.2012 | Renewal fee patent year 05 | 24.05.2012 | Renewal fee patent year 06 | 24.05.2012 | Renewal fee patent year 07 | 25.01.2013 | Renewal fee patent year 08 | 27.01.2014 | Renewal fee patent year 09 | 27.01.2015 | Renewal fee patent year 10 | 27.01.2016 | Renewal fee patent year 11 | 27.01.2017 | Renewal fee patent year 12 | 29.01.2018 | Renewal fee patent year 13 |
| Opt-out from the exclusive Tooltip competence of the Unified Patent Court | See the Register of the Unified Patent Court for opt-out data | ||
| Responsibility for the accuracy, completeness or quality of the data displayed under the link provided lies entirely with the Unified Patent Court. | Lapses during opposition Tooltip | FR | 31.01.2019 | [2019/49] | Documents cited: | Search | [A]US5398539 (GORDON GARY B [US], et al) [A] 1-25 * the whole document *; | [X]US6802967 (MASUDA JUNICHI [US], et al) [X] 1,2,24 * example .; claim - *; | [X] - WAGNER K ET AL, "AN AUTOMATED ON-LINE MULTIDIMENSIONAL HPLC SYSTEM FOR PROTEIN AND PEPTIDE MAPPING WITH INTEGRATED SAMPLE PREPARATION", ANALYTICAL CHEMISTRY, AMERICAN CHEMICAL SOCIETY, US, (20020215), vol. 74, no. 4, ISSN 0003-2700, pages 809 - 820, XP001115830 [X] 1,2,22,24,25 * Paragraph "Experimental section";; figure 1 * DOI: http://dx.doi.org/10.1021/ac010627f | [X] - VENKATRAMANI C J ET AL, "AN AUTOMATED ORTHOGONAL TWO-DIMENSIONAL LIQUID CHROMATOGRAPH", ANALYTICAL CHEMISTRY, AMERICAN CHEMICAL SOCIETY, US, (20030715), vol. 75, no. 14, ISSN 0003-2700, pages 3484 - 3494, XP001176027 [X] 25 * Paragraph "Experimental Section";; figure 1 * DOI: http://dx.doi.org/10.1021/ac030075w | [X] - M.A.STREGE & AL., "Mixed-mode anion-cation exchange/hydrophilic interaction liquid chromatography-electrospray mass spectrometry as an alternative to reversed phase for small molecule drug discovery", ANALYTICAL CHEMISTRY, (20001001), vol. 72, no. 19, doi:10.1021/ac000338b, pages 4629 - 4633, XP002566414 [X] 25 * Paragraph "Experimental section" * DOI: http://dx.doi.org/10.1021/AC000338B | [A] - PATRICK J. SLONECKER ET AL, "Informational Orthogonality of Two-Dimensional Chromatographic Separations", ANALYTICAL CHEMISTRY, (19960101), vol. 68, no. 4, doi:10.1021/ac950852v, ISSN 0003-2700, pages 682 - 689, XP055032200 [A] 1-25 * abstract * DOI: http://dx.doi.org/10.1021/ac950852v | [X] - OPITECK G J ET AL, "COMPREHENSIVE TWO-DIMENSIONAL HIGH-PERFORMANCE LIQUID CHROMATOGRAPHY FOR THE ISOLATION OF OVEREXPRESSED PROTEINS AND PROTEOME MAPPING", ANALYTICAL BIOCHEMISTRY, ACADEMIC PRESS INC, NEW YORK, (19980501), vol. 258, no. 2, doi:10.1006/ABIO.1998.2588, ISSN 0003-2697, pages 349 - 361, XP000960771 [X] 1,2,22,24 * abstract * DOI: http://dx.doi.org/10.1006/abio.1998.2588 | Examination | - MARTIN GILAR ET AL, "Two-Dimensional Separation of Peptides Using RP-RP-HPLC System with Different pH in First and Second Separation Dimensions", JOURNAL OF SEPARATION SCIENCE, WILEY, DE, (20050901), vol. 28, no. 24, doi:10.1002/JSSC.200500116, ISSN 1615-9306, pages 1694 - 1703, XP008144253 DOI: http://dx.doi.org/10.1002/jssc.200500116 | by applicant | US6730228 | - TRANCHIDA, PQ ET AL., J. CHROMATOGR A., (2004), vol. 1054, no. 1-2, pages 3 - 16 | - GILAR, M.; OLIVOVA, P.; DALY, A. E.; GEBLER, J. C., ANAL. CHEM., (2005), vol. 77, pages 6426 - 6434 | - GILAR, M.; OLIVOVA, P.; DALY, A. E.; GEBLER, J., C. F SEP. SCI., (2005), vol. 28, pages 1694 - 1703 | - K.D. WYNDHAM ET AL., ANAL. CHEM, (2003), vol. 75, pages 6781 - 6788 | other | - WAGNER K. ET AL, "An Automated On-Line Multidimensional HPLC System for Protein and Peptide Mapping with Integrated Sample Preparation", Analytical Chemistry, vol. 74, no. 4, (20020215), pages 809 - 820, XP001115830 DOI: http://dx.doi.org/10.1021/ac010627f | - OPITECK et al., "Comprehensive Two-Dimensional High-Performance Liquid Chromatography for the Isolation of Overexpressed Proteins and Proteome Mapping", Analytical Biochemistry, (19980500), vol. 258, pages 349 - 361, XP000960771 DOI: http://dx.doi.org/10.1006/abio.1998.2588 | - DOLAN, "A Guide to HPLC and LC-MS Buffer Selection", ACE HPLC Columns, (20060705), XP055318419 | - CHUANG et al., "Chromatographic methods for product-profile analysis and isolation of oligosaccharides produced by heparinase-catalyzed depolymerization of heparin", J. Chromatogr. A, (20011012), vol. 932, no. 1-2, pages 65 - 74, XP004308398 DOI: http://dx.doi.org/10.1016/S0021-9673(01)01241-9 | - WAGNER et al., "Protein mapping by two-dimensional high performance liquid chromatography", J. Chromatogr. A, (20001006), vol. 893, no. 2, pages 293 - 305, XP004212037 DOI: http://dx.doi.org/10.1016/S0021-9673(00)00736-6 | - KOHNE et al., "Coupling of a microbore column with a column packed with non-porous particles for fast comprehensive two-dimensional high-performance liquid chromatography", J. Chromatogr. A, (19990611), vol. 845, no. 1-2, pages 463 - 469, XP027232085 | Opposition | US5658739 | WO0250531 | US2004124128 | US6802967 | - Paul Rainville et al., "The influence of pH on elution order of tryptic peptides on reversed-phase columns: A unique approach to multidimensional liquid chromatograpic separations for proteomics", Waters Corporation, ASMS, Orlando, Florida, (20020000), URL: http://www.waters.com/webassets/cms/library/docs/wa20271.pdf, XP055550807 | - PAUL RAINVILLE et al., "The Influence of pH on Elution Order of Tryptic Peptides on Reversed-Phase Columns: A Unique Approach to Multidimensional Liquid Chromatography Separations for Proteomics", ASMS, (20020000), page 1, XP055550807 | - MORITZ et al., "High-Speed Chromatographic Separation of Proteins and Peptides for High Sensitivity Microsequence Analysis", Methods in Protein Structure Analysis, New York, (19950000), pages 27 - 38, XP055620083 DOI: http://dx.doi.org/10.1007/978-1-4899-1031-8_3 | - VAN GYSEGHEM et al., "Determining orthogonal chromatographic systems prior to the development of methods to characzterise impurities in drug substances", J. Chromatogr. A, (20030000), vol. 988, doi:doi:10.1016/S0021-9673(02)02012-5, pages 77 - 93, XP004405865 DOI: http://dx.doi.org/10.1016/S0021-9673(02)02012-5 | - GUO et al., "Prediction of Peptide Retention Times in Reversed-Phase High- Performance Liquid Chromatography", Journal of Chromatography, (19860000), vol. 359, doi:doi:10.1016/0021-9673(86)80102-9, pages 499 - 517, XP009032750 DOI: http://dx.doi.org/10.1016/0021-9673(86)80102-9 | - PALIWAL et al., "Rapid Separations of Proteins by Liquid Chromatography", Methods in Enzymology, (19960000), vol. 270, pages 133 - 151, XP055620091 DOI: http://dx.doi.org/10.1016/S0076-6879(96)70008-3 | - WAGNER et al., "An Automated On-Line Multidimensional HPLC System for Protein and Peptide Mapping with Integrated Sample Preparation", Anal. Chem., (20020000), vol. 74, doi:doi:10.1021/ac010627f, pages 809 - 820, XP001115830 DOI: http://dx.doi.org/10.1021/ac010627f | - OPITECK et al., "Comprehensive Two-Dimensional High-Performance Liquid Chromatography for the Isolation of Overexpressed Proteins and Proteome Mapping", Analytical Biochemistry, (19980000), vol. 258, doi:doi:10.1006/abio.1998.2588, pages 349 - 361, XP000960771 DOI: http://dx.doi.org/10.1006/abio.1998.2588 | - DOLAN, "A Guide to HPLC and LC-MS Buffer Selection", ACE HPLC Columns, pages 1 - 20 | - LINDNER et al., "Application of hydrophilic-interaction liquid chromatography to the separation of phosphorylated H1 histones", J. Chromatogr. A, (19970000), vol. 782, doi:doi:10.1016/S0021-9673(97)00468-8, pages 55 - 62, XP004096293 DOI: http://dx.doi.org/10.1016/S0021-9673(97)00468-8 | - GILAR et al., "Orthogonality of Separation in Two-Dimensional Liquid Chromatography", Anal. Chem, (20050000), vol. 77, pages 6426 - 6434, XP055620103 DOI: http://dx.doi.org/10.1021/ac050923i | - GILAR et al., "Two-dimensional separation of peptides using RP-RP-HPLC- system with different pH in first and second separation dimensions", J. Sep. Sci., (20050000), vol. 28, doi:doi:10.1002/jssc.200500116, pages 1694 - 1703, XP008144253 DOI: http://dx.doi.org/10.1002/jssc.200500116 |