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Extract from the Register of European Patents

EP About this file: EP2540296

EP2540296 - Arminothiazole derivatives as human stearoyl-coa desaturase inhibitors [Right-click to bookmark this link]
StatusThe application is deemed to be withdrawn
Status updated on  09.01.2015
Database last updated on 30.07.2024
Most recent event   Tooltip09.01.2015Application deemed to be withdrawnpublished on 11.02.2015  [2015/07]
Applicant(s)For all designated states
Xenon Pharmaceuticals Inc.
3650 Gilmore Way
Burnaby, BC V5G 4W8 / CA
[2013/01]
Inventor(s)01 / Fu, Jian-Min
3170 Quintette Crescent
Coquitlam, BC V3E 3B6 / CA
02 / Hou, Duanjie
Nr. 46-7088
17th Avenue
Burnaby BC V3N 1K5 / CA
03 / Rajender, Kamboj
5809 Sperling Avenue
Burnaby BC V5E 2T6 / CA
04 / Vishnumurthy, Kodumuru
13 Jutith Lane
Waltham MA 02452 / US
05 / Prokovskaia, Natalia
100-845 Mcbride Blvd
New Westminster BC V3L 2C2 / CA
06 / Raina, Vandna
PH3, 2763 Chandlery Place
Vancouver BC V5S 4V4 / CA
07 / Sun, Shaoyi
Nr. 5-1200 Brunette Avenue
Coquitlam BC V3K 1G3 / CA
08 / Sviridov, Serguei
1904-5885 Olive Avenue
Burnaby BC V5H 4N8 / CA
09 / Zhang, Zaihui
4038 MacDonald Street
Vancouver BC V6L 2N9 / CA
 [2013/02]
Representative(s)Grünecker Patent- und Rechtsanwälte PartG mbB
Leopoldstraße 4
80802 München / DE
[N/P]
Former [2013/01]Grünecker, Kinkeldey, Stockmair & Schwanhäusser
Leopoldstrasse 4
80802 München / DE
Application number, filing date12005821.905.06.2006
[2013/01]
Priority number, dateUS20050687133P03.06.2005         Original published format: US 687133 P
[2013/01]
Filing languageEN
Procedural languageEN
PublicationType: A1 Application with search report 
No.:EP2540296
Date:02.01.2013
Language:EN
[2013/01]
Search report(s)(Supplementary) European search report - dispatched on:EP05.12.2012
ClassificationIPC:A61K31/426, A61K31/427, A61K31/4439, A61P3/00, A61P9/12, A61P17/06, A61P17/10, A61P19/06, C07D277/82, C07D417/12
[2013/01]
CPC:
A61K31/426 (EP,US); C07D277/587 (US); A61K31/427 (EP,US);
A61K31/4439 (EP,US); A61K31/5377 (US); A61K31/616 (US);
A61K38/26 (US); A61K38/28 (US); A61K45/06 (US);
A61P1/16 (EP); A61P17/00 (EP); A61P17/02 (EP);
A61P17/06 (EP); A61P17/08 (EP); A61P17/10 (EP);
A61P19/06 (EP); A61P3/00 (EP); A61P3/04 (EP);
A61P3/06 (EP); A61P3/10 (EP); A61P35/00 (EP);
A61P43/00 (EP); A61P7/02 (EP); A61P9/10 (EP);
A61P9/12 (EP); C07D277/56 (EP,US); C07D417/06 (US);
C07D417/12 (EP,US) (-)
Designated contracting statesAT,   BE,   BG,   CH,   CY,   CZ,   DE,   DK,   EE,   ES,   FI,   FR,   GB,   GR,   HU,   IE,   IS,   IT,   LI,   LT,   LU,   LV,   MC,   NL,   PL,   PT,   RO,   SE,   SI,   SK,   TR [2013/01]
TitleGerman:Arminothiazolderivate als menschliche Stearoyl-Coa-Desaturase-Hemmer[2013/01]
English:Arminothiazole derivatives as human stearoyl-coa desaturase inhibitors[2013/01]
French:Dérivés d'arminothiazole utilisés comme inhibiteurs de la stéaroyl-coa désaturase humaine[2013/01]
Examination procedure01.07.2013Examination requested  [2013/33]
18.10.2013Amendment by applicant (claims and/or description)
29.04.2014Despatch of a communication from the examining division (Time limit: M04)
10.09.2014Application deemed to be withdrawn, date of legal effect  [2015/07]
07.10.2014Despatch of communication that the application is deemed to be withdrawn, reason: reply to the communication from the examining division not received in time  [2015/07]
Parent application(s)   TooltipEP06784578.4  / EP2029138
Divisional application(s)The date of the Examining Division's first communication in respect of the earliest application for which a communication has been issued (EP20060784578) is  13.08.2010
Request for further processing for:The application is deemed to be withdrawn due to failure to reply to the Extended European Search Report/Written Opinion of the International Searching Authority/International Preliminary Examination Report/Supplementary international search report/Supplementary European search report
18.10.2013Request for further processing filed
18.10.2013Full payment received (date of receipt of payment)
Request granted
04.11.2013Decision despatched
Fees paidRenewal fee
10.08.2012Renewal fee patent year 03
10.08.2012Renewal fee patent year 04
10.08.2012Renewal fee patent year 05
10.08.2012Renewal fee patent year 06
10.08.2012Renewal fee patent year 07
27.06.2013Renewal fee patent year 08
Penalty fee
Additional fee for renewal fee
30.06.201409   M06   Not yet paid
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Documents cited:Search[AD]WO2005011655  (XENON PHARMACEUTICALS INC [CA], et al) [AD] 1-15* Page 144, lines 16-17,; page 1, line 3 - line 8 *;
 [X]  - WITYAK, JOHN ET AL, "Discovery and initial SAR of 2-amino-5-carboxamidothiazoles as inhibitors of the Src-family kinase p56Lck", BIOORGANIC & MEDICINAL CHEMISTRY LETTERS , 13(22), 4007-4010 CODEN: BMCLE8; ISSN: 0960-894X, (2003), XP002402709 [X] 7,13,14 * the whole document *

DOI:   http://dx.doi.org/10.1016/j.bmcl.2003.08.054
 [X]  - OHKUBO, MITSURU ET AL, "Studies on cerebral protective agents. VIII. Synthesis of 2-aminothiazoles and 2-thiazolecarboxamides with anti-anoxic activity", CAPLUS, CHEMICAL ABSTRACTS SERVICE, COLUMBUS, OHIO, US, Database accession no. 1995:902192, URL: STN, XP002402712 [X] 7,13,14 * the whole document *
 [X]  - SINGH, S. N. ET AL, "New local anesthetics", CA, CHEMICAL ABSTRACTS SERVICE, COLUMBUS, OHIO, US, Database accession no. 1972:564589, URL: STN, XP002402713 [X] 7,13,14 * the whole document *
by applicantWO0162954
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 WO2005011657
 WO2005011656
 WO2005011655
 WO2005011654
 WO2005011653
 WO2006014168
 WO2006034338
 WO2006034446
 WO2006034441
 WO2006034440
 WO2006034341
 WO2006034315
 WO2006034312
 WO2006034279
    - JEFFCOAT, R. ET AL., EUR. J. BIOCHEM., (1979), vol. 101, no. 2, pages 439 - 445
    - DE ANTUENO, R. ET AL., LIPIDS, (1993), vol. 28, no. 4, pages 285 - 290
    - ATTIE, A.D. ET AL., "Relationship between stearoyl-CoA desaturase activity and plasma triglycerides in human and mouse hypertriglyceridemia", J. LIPID RES., (2002), vol. 43, no. 11, pages 1899 - 907
    - COHEN, P. ET AL., "Role for stearoyl-CoA desaturase-1 in leptin mediated weight loss", SCIENCE, (2002), vol. 297, no. 5579, pages 240 - 3
    - NTAMBI, J. M. ET AL., "Loss of stearoyl-CoA desaturase-1 function protects mice against adiposity", PROC. NATL. ACAD. SCL U.S.A., (2002), vol. 99, no. 7, pages 11482 - 6
    - BUNDGARD, H., Design of Prodrugs, ELSEVIER, (1985), pages 7 - 9,21-24
    - HIGUCHI, T. ET AL., Pro-drugs as Novel Delivery Systems, vol. 14
    - GHIBAUDI, L. ET AL., OBES. RES., (2002), vol. 10, pages 956 - 963
    - GRUNDY, S., CARDIOL. REV., (2006), vol. 13, no. 6, pages 322 - 327
    - SHANKLIN J.; SUMMERVILLE C., PROC. NATT. ACAD. SCI. USA, (1991), vol. 88, pages 2510 - 2514
    - REMINGTON'S PHARMACEUTICAL SCIENCES, MACK PUB. CO.
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