EP2474556 - APCDD1 inhibitors for treating, diagnosing or detecting cancer [Right-click to bookmark this link] | Status | The application is deemed to be withdrawn Status updated on 17.10.2014 Database last updated on 09.09.2024 | Most recent event Tooltip | 17.10.2014 | Application deemed to be withdrawn | published on 19.11.2014 [2014/47] | Applicant(s) | For all designated states Novartis AG Lichtstrasse 35 4056 Basel / CH | [2012/28] | Inventor(s) | 01 /
Janatpour, Mary J. P.O. Box 8097 Emeryville, CA 94602-8097 / US | 02 /
Fanidi, Abdallah 4560 Horton Street Emeryville, CA 94608-2916 / US | 03 /
Shen, Shanling P.O. Box 8097 Emeryville, CA 94602-8097 / US | 04 /
Yu, Karen P.O. Box 8097 Emeryville, CA 94602-8097 / US | [2013/21] |
Former [2012/28] | 01 /
JANATPOUR, Mary J. P.O. Box 8097 Emeryville, CA California 94602-8097 / US | ||
02 /
FANIDI, Abdallah 4560 Horton Street Emeryville, 94608-2916 / US | |||
03 /
SHEN, Shanling P.O. Box 8097 Emeryville, CA California 94602-8097 / US | |||
04 /
YU, Karen P.O. Box 8097 Emeryville, CA California 94602-8097 / US | Representative(s) | Marshall, Cameron John Carpmaels & Ransford LLP One Southampton Row London WC1B 5HA / GB | [N/P] |
Former [2012/28] | Marshall, Cameron John Carpmaels & Ransford One Southampton Row London WC1B 5HA / GB | Application number, filing date | 12163296.2 | 14.03.2008 | [2012/28] | Priority number, date | US20070894806P | 14.03.2007 Original published format: US 894806 P | [2012/28] | Filing language | EN | Procedural language | EN | Publication | Type: | A2 Application without search report | No.: | EP2474556 | Date: | 11.07.2012 | Language: | EN | [2012/28] | Type: | A3 Search report | No.: | EP2474556 | Date: | 17.10.2012 | Language: | EN | [2012/42] | Type: | A8 Corrected patent application | No.: | EP2474556 | Date: | 22.05.2013 | [2013/21] | Search report(s) | (Supplementary) European search report - dispatched on: | EP | 19.09.2012 | Classification | IPC: | C07K14/47, C07K16/30, C12N15/13, A61K39/395 | [2012/28] | CPC: |
A61P35/00 (EP);
A61P35/04 (EP);
C07K14/4748 (EP,US);
C07K16/3046 (EP,US);
C12N15/113 (EP,US);
C07K2317/34 (EP,US);
C12N2310/14 (EP,US)
(-)
| Designated contracting states | AT, BE, BG, CH, CY, CZ, DE, DK, EE, ES, FI, FR, GB, GR, HR, HU, IE, IS, IT, LI, LT, LU, LV, MC, MT, NL, NO, PL, PT, RO, SE, SI, SK, TR [2012/28] | Extension states | AL | Not yet paid | BA | Not yet paid | MK | Not yet paid | RS | Not yet paid | Title | German: | APCDD1-Inhibitoren zur Behandlung, Diagnose und Erkennung von Krebs | [2012/28] | English: | APCDD1 inhibitors for treating, diagnosing or detecting cancer | [2012/28] | French: | Inhibiteurs APCDD1 pour traiter, diagnostiquer ou détecter le cancer | [2012/28] | Examination procedure | 15.04.2013 | Amendment by applicant (claims and/or description) | 15.04.2013 | Examination requested [2013/22] | 22.11.2013 | Despatch of a communication from the examining division (Time limit: M06) | 03.06.2014 | Application deemed to be withdrawn, date of legal effect [2014/47] | 01.07.2014 | Despatch of communication that the application is deemed to be withdrawn, reason: reply to the communication from the examining division not received in time [2014/47] | Parent application(s) Tooltip | EP08743904.8 / EP2125898 | Divisional application(s) | The date of the Examining Division's first communication in respect of the earliest application for which a communication has been issued (EP20080743904) is 26.03.2010 | Fees paid | Renewal fee | 05.04.2012 | Renewal fee patent year 03 | 05.04.2012 | Renewal fee patent year 04 | 05.04.2012 | Renewal fee patent year 05 | 11.03.2013 | Renewal fee patent year 06 | 13.03.2014 | Renewal fee patent year 07 |
Opt-out from the exclusive Tooltip competence of the Unified Patent Court | See the Register of the Unified Patent Court for opt-out data | ||
Responsibility for the accuracy, completeness or quality of the data displayed under the link provided lies entirely with the Unified Patent Court. | Documents cited: | Search | [Y]US2003148410 (BERGER ALLISON [US], et al) [Y] 1-12 * paragraphs [0013] - [0024] - [0059] , [0112] , [0131] , [0143] , [0277] , [0304] * * table 1 *; | [Y]WO03104276 (ONCOTHERAPY SCIENCE INC [JP], et al) [Y] 1-12 * page 32, line 27 - page 33, line 34 * * page 34, lines 1-4 * * examples 26,27 * * claims 1-33 *; | [Y] - TAKAHASHI MEIKO ET AL, "Isolation of a novel human gene, APCDD1, as a direct target of the beta-catenin/T-cell factor 4 complex with probable involvement in colorectal carcinogenesis", CANCER RESEARCH, (20021015), vol. 62, no. 20, ISSN 0008-5472, pages 5651 - 5656, XP002503180 [Y] 1-12 * see the whole document * | by applicant | US4816567 | US5500362 | US5821337 | US5530101 | US5585089 | US2004175756 | US2005053973 | US2005048512 | US2006008844 | WO9835036 | WO0044895 | WO0136646 | WO9932619 | WO0129058 | US5545807 | US5545806 | US5569825 | US5625126 | US5633425 | US5661016 | WO9208495 | WO9114438 | WO8912624 | US5314995 | EP0396387 | US6075181 | US6091001 | US6114598 | US5545403 | US5545405 | US5998144 | WO9824893 | WO9110741 | WO9630498 | WO9402602 | US5939598 | US5766886 | WO9633735 | WO03041600 | US2003133939 | US2003118592 | US4275149 | US4737456 | WO02098883 | WO2004103272 | US5714586 | US5712374 | US5264586 | US5773001 | WO9321232 | WO9411026 | WO03026577 | WO02088172 | WO8101145 | WO8807378 | US4975278 | US4766106 | US4179337 | US4495285 | US4609546 | US5637677 | US2003028071 | US2003032995 | US4675187 | - TAKAHASHI ET AL., CANCER RESEARCH, (2002), vol. 62, pages 5651 - 5656 | - S. COLOWICK AND N. KAPLAN, Methods In Enzymology, ACADEMIC PRESS, INC. | - D.M. WEIR AND C.C. BLACKWELL,, Handbook of Experimental Immunology, BLACKWELL SCIENTIFIC PUBLICATIONS, (1986), vol. I-IV | - HOSHINO ET AL., INT. J. CANCER, (1986), vol. 38, page 369 | - CAMPANA ET AL., J. IMMUNOL. METH., (1988), vol. 107, page 79 | - CHADLEE, D. N., J. BIOL. CHEM, (1995), vol. 270, pages 20098 - 105 | - CHEN, J., ONCOGENE, (1996), vol. 13, pages 1395 - 403 | - JEOUNG, J., J. BIOL. CHEM., (1995), vol. 270, pages 18367 - 73 | - VOYTIK-HARBIN S L ET AL., IN VITRO CELL DEV BIOL ANIM, (1998), vol. 34, pages 239 - 46 | - GRAY J W ET AL., INT J RADIAT BIOL RELAT STUD PHYS CHEM MED, (1986), vol. 49, pages 237 - 55 | - KOHLER ET AL., NATURE, (1975), vol. 256, page 495 | - CLACKSON ET AL., NATURE, (1991), vol. 352, pages 624 - 628 | - MARKS, J. MOL. BIOL., (1991), vol. 222, pages 581 - 597 | - MORRISON ET AL., PROC. NATL. ACAD. SCI. USA, (1984), vol. 81, pages 6851 - 6855 | - ZAPATA ET AL., PROTEIN ENG., (1995), vol. 8, no. 10, pages 1057 - 1062 | - RAVETCH; KINET, ANNU. REV. IMMUNOL., (1991), vol. 9, page 464 | - CLYNES ET AL., USA, (1998), vol. 95, pages 652 - 656 | - DARON, ANNU. REV. IMMUNOL., (1997), vol. 15, pages 203 - 234 | - RAVETCH; KINET, ANNU. REV. IMMUNOL, (1991), vol. 9, pages 457 - 92 | - CAPEL ET AL., IMMUNOMETHODS, (1994), vol. 4, pages 25 - 34 | - DE HAAS ET AL., J. LAB. CLIN. MED., (1995), vol. 126, pages 330 - 41 | - GUYER ET AL., J. IMMUNOL., (1976), vol. 117, page 587 | - KIM ET AL., J. IMMUNOL., (1994), vol. 24, page 249 | - GAZZANO-SANTORO ET AL., J. MIMUNOL. METHODS, (1996), vol. 202, page 163 | - CHOTHIA ET AL., J. MOL. BIOL., (1987), vol. 196, pages 901 - 917 | - SMITH; WATERMAN, ADV. APPL. MATH., (1981), vol. 2, pages 482 - 489 | - MARKS ET AL., BIO/TECHNOLOGY, (1992), vol. 10, pages 779 - 783 | - LONBERG ET AL., NATURE, (1994), vol. 368, pages 856 - 859 | - MORRISON, NATURE, (1994), vol. 368, pages 812 - 13 | - FISHWILD ET AL., NATURE BIOTECHNOLOGY, (1996), vol. 14, pages 845 - 51 | - NEUBERGER, NATURE BIOTECHNOLOGY, (1996), vol. 14, page 826 | - LONBERG; HUSZAR, INTERN. REV. IMMUNOL., (1995), vol. 13, pages 65 - 93 | - JONES ET AL., NATURE, (1986), vol. 321, pages 522 - 525 | - MORRISON ET AL., PROC. NATL. ACAD. SCI, (1984), vol. 81, pages 6851 - 6855 | - MORRISON; OI, ADV. IMMUNOL., (1988), vol. 44, pages 65 - 92 | - VERHOEYER ET AL., SCIENCE, (1988), vol. 239, pages 1534 - 1536 | - PADLAN, MOLEC. IMMUN., (1991), vol. 28, pages 489 - 498 | - PADLAN, MOLEC. IMMUNOL., (1994), vol. 31, no. 3, pages 169 - 217 | - KETTLEBOROUGH, C.A. ET AL., PROTEIN ENG., (1991), vol. 4, no. 7, pages 773 - 83 | - MCCAFFERTY ET AL., NATURE, (1990), vol. 348, pages 552 - 554 | - MARKS ET AL., J. MOL. BIOL., (1991), vol. 222, pages 581 - 597 | - KOHLER ET AL., NATURE, (1975), vol. 256, pages 495 - 496 | - IMMUNOL., vol. 147, page 8 | - BANCHEREAU ET AL., CLIN. IMMUNOL. SPECTRUM, (1991), vol. 3, page 8 | - BANCHEREAU ET AL., SCIENCE, (1991), vol. 251, page 70 | - HOOGENBOOM; WINTER, J. MOL. BIOL., (1991), vol. 227, page 381 | - MARKS ET AL., J. MOL. BIOL., (1991), vol. 222, page 581 | - COLE ET AL., Monoclonal Antibodies and Cancer Therapy, ALAN R. LISS, (1985), page 77 | - BOERNER ET AL., J. IMMUNOL., (1991), vol. 147, no. 1, page 86 95 | - MARKS ET AL., BIO/TECHNOLOGY, (1992), vol. 10, page 779 783 | - MORRISON, NATURE, (1994), vol. 368, page 812 13 | - LONBERG; HUSZAR, INTERN. REV. IMMUNOL., (1995), vol. 13, page 65 93 | - FANG ET AL., NAT. BIOTECHNOL., (2005), vol. 23, pages 584 - 590 | - KYTE, J.; DOLITTLE, R.F., J. MOL. BIOL., (1982), vol. 157, pages 105 - 132 | - HOPP, T.P.; WOODS, K.R., PROC. NATL. ACAD. SCI. USA, (1981), vol. 78, pages 3824 - 3828 | - HOPP, T.J.; WOODS, K.R., MOL. IMMUNOL., (1983), vol. 20, pages 483 - 489 | - HOPP, TJ., J. IMMUNOL. METHODS, (1986), vol. 88, pages 1 - 18 | - JAMESON, B.A.; WOLF, H., COMPUT. APPL. BIOSCI., (1988), vol. 4, pages 181 - 186 | - EMINI, E.A.; SCHLIEF, W.A.; COLONNO, R.J.; WIMMER, E., VIROLOGY, (1985), vol. 140, pages 13 - 20 | - K. HOFINANN; W. STOFFEL, "TMbase - A database of membrane spanning proteins segments", BIOL. CHEM. HOPPE-SEYLER, (1993), vol. 374, page 166 | - A. KROGH; B. LARSSON; G. VON HEIJNE; E. L. L. SONNHAMMER, "Predicting transmembrane protein topology with a hidden Markov model: Application to complete genomes", JOURNAL OF MOLECULAR BIOLOGY, (200101), vol. 305, no. 3, doi:doi:10.1006/jmbi.2000.4315, pages 567 - 580, XP004469188 DOI: http://dx.doi.org/10.1006/jmbi.2000.4315 | - BEDNSTEN ET AL., J MOL BIOL., (20040716), vol. 340, no. 4, pages 783 - 95 | - SCATCHARD, ANN. NY ACAD. SCI., (1949), vol. 51, pages 660 - 672 | - GETZOFF ET AL., ADV. IN IMMUNOL., (1988), vol. 43, pages 1 - 98 | - BENJAMIN ET AL., ANN. REV. IMMUNOL., (1984), vol. 2, pages 67 - 101 | - COLIGEN ET AL.,, Current Protocols in Immunology, WILEY-INTERSCIENCE, (1991), vol. 1, 2 | - J. LANGONE & H. VAN VUNAKIS, Enzyme Immunoassay, in Methods in Enzym., ACADEMIC PRESS, (1981), vol. 73, pages 147 - 166 | - CHARI ET AL., CANCER RESEARCH, (1992), vol. 52, pages 127 - 131 | - PAYNE, CANCER CELL, (2003), vol. 3, pages 207 - 212 | - HINMAN ET AL., CANCER RESEARCH, (1993), vol. 53, pages 3336 - 3342 | - LODE ET AL., CANCER RESEARCH, (1998), vol. 58, pages 2925 - 2928 | - DECY ET AL., FASEB JOURNAL, (2004), vol. 18, no. 3, pages 565 - 567 | - DATTA ET AL., ANN N.Y. ACAD. SCI, (2003), vol. 1002, pages 105 - 111 | - VITETTA ET AL., SCIENCE, (1987), vol. 238, page 1098 | - MASSEY, NATURE, (1987), vol. 328, pages 457 - 458 | - NEUBERGER ET AL., NATURE, (1984), vol. 312, pages 604 - 608 | - GAZZANO-SANTORO ET AL., J. IMMUNOL. METHODS, (1997), vol. 202, pages 163 - 171 | - KARJALAINEN; MANTYJARVI, ACTA PATHOL MICROBIOL SCAND [C, (198110), vol. 89, no. 5, pages 315 - 9 | - YAGLE ET AL., J NUCL MED., (200504), vol. 46, no. 4, pages 658 - 66 | - WILMAN, "Prodrugs in Cancer Chemotherapy", BIOCHEMICAL SOCIETY TRANSACTIONS, (1986), vol. 14, pages 375 - 382 | - "Prodrugs: A Chemical Approach to Targeted Drug Delivery", STELLA ET AL., Directed Drug Delivery, HUMANA PRESS, (1985), pages 247 - 267 |