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Extract from the Register of European Patents

EP About this file: EP2559756

EP2559756 - Single pluripotent stem cell culture [Right-click to bookmark this link]
StatusNo opposition filed within time limit
Status updated on  23.10.2020
Database last updated on 30.10.2024
FormerThe patent has been granted
Status updated on  15.11.2019
FormerGrant of patent is intended
Status updated on  04.06.2019
FormerExamination is in progress
Status updated on  30.11.2016
Most recent event   Tooltip24.06.2022Lapse of the patent in a contracting state
New state(s): CY, HU, MT
published on 27.07.2022  [2022/30]
Applicant(s)For all designated states
Janssen Biotech, Inc.
800/850 Ridgeview Drive
Horsham, PA 19044 / US
[2019/47]
Former [2013/08]For all designated states
Lifescan, Inc.
1000 Gibraltar Drive
Milpitas, CA 94066 / US
Inventor(s)01 / Nelson, Shelley
199 Grandview Road
Skillman, NJ 08558 / US
 [2013/08]
Representative(s)Vossius & Partner Patentanwälte Rechtsanwälte mbB
Siebertstrasse 3
81675 München / DE
[2019/51]
Former [2013/08]Bullett, Rachel Margaret, et al
Carpmaels & Ransford One Southampton Row London
WC1B 5HA / GB
Application number, filing date12176076.330.06.2008
[2013/08]
Priority number, dateUS20070947444P01.07.2007         Original published format: US 947444 P
[2013/08]
Filing languageEN
Procedural languageEN
PublicationType: A1 Application with search report 
No.:EP2559756
Date:20.02.2013
Language:EN
[2013/08]
Type: B1 Patent specification 
No.:EP2559756
Date:18.12.2019
Language:EN
[2019/51]
Search report(s)(Supplementary) European search report - dispatched on:EP18.01.2013
ClassificationIPC:C12N5/0735
[2013/08]
CPC:
C12N5/0606 (EP,KR); C12N5/0676 (KR); C12N2509/00 (EP,KR);
C12N2533/90 (EP,KR)
Designated contracting statesAT,   BE,   BG,   CH,   CY,   CZ,   DE,   DK,   EE,   ES,   FI,   FR,   GB,   GR,   HR,   HU,   IE,   IS,   IT,   LI,   LT,   LU,   LV,   MC,   MT,   NL,   NO,   PL,   PT,   RO,   SE,   SI,   SK,   TR [2019/51]
Former [2013/08]AT,  BE,  BG,  CH,  CY,  CZ,  DE,  DK,  EE,  ES,  FI,  FR,  GB,  GR,  HR,  HU,  IE,  IS,  IT,  LI,  LT,  LU,  LV,  MC,  MT,  NL,  NO,  PL,  PT,  RO,  SE,  SI,  SK,  TR 
TitleGerman:Kultur einzelner pluripotenter Stammzellen[2019/51]
English:Single pluripotent stem cell culture[2013/08]
French:Culture de cellules souches pluripotentes uniques[2013/08]
Former [2013/08]Einfach pluripotente Stammzellenkultur
Examination procedure20.08.2013Examination requested  [2013/39]
26.09.2013Despatch of communication that the application is deemed to be withdrawn, reason: reply to the Extended European Search Report/Written Opinion of the International Searching Authority/International Preliminary Examination Report/Supplementary international search report not received in time
04.12.2013Amendment by applicant (claims and/or description)
27.02.2014Despatch of a communication from the examining division (Time limit: M06)
10.09.2014Reply to a communication from the examining division
24.03.2015Despatch of a communication from the examining division (Time limit: M04)
03.08.2015Reply to a communication from the examining division
21.07.2016Despatch of a communication from the examining division (Time limit: M04)
29.11.2016Reply to a communication from the examining division
23.01.2017Despatch of a communication from the examining division (Time limit: M04)
02.06.2017Reply to a communication from the examining division
18.01.2018Despatch of a communication from the examining division (Time limit: M06)
30.07.2018Reply to a communication from the examining division
05.06.2019Communication of intention to grant the patent
15.10.2019Fee for grant paid
15.10.2019Fee for publishing/printing paid
15.10.2019Receipt of the translation of the claim(s)
Parent application(s)   TooltipEP08772255.9  / EP2173862
Divisional application(s)The date of the Examining Division's first communication in respect of the earliest application for which a communication has been issued (EP20080772255) is  13.07.2010
Opposition(s)21.09.2020No opposition filed within time limit [2020/48]
Request for further processing for:The application is deemed to be withdrawn due to failure to reply to the examination report
10.09.2014Request for further processing filed
10.09.2014Full payment received (date of receipt of payment)
Request granted
18.09.2014Decision despatched
The application is deemed to be withdrawn due to failure to reply to the Extended European Search Report/Written Opinion of the International Searching Authority/International Preliminary Examination Report/Supplementary international search report/Supplementary European search report
04.12.2013Request for further processing filed
04.12.2013Full payment received (date of receipt of payment)
Request granted
18.12.2013Decision despatched
Fees paidRenewal fee
22.08.2012Renewal fee patent year 03
22.08.2012Renewal fee patent year 04
22.08.2012Renewal fee patent year 05
10.06.2013Renewal fee patent year 06
31.03.2014Renewal fee patent year 07
10.06.2015Renewal fee patent year 08
10.06.2016Renewal fee patent year 09
16.06.2017Renewal fee patent year 10
12.06.2018Renewal fee patent year 11
27.06.2019Renewal fee patent year 12
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See the Register of the Unified Patent Court for opt-out data
Responsibility for the accuracy, completeness or quality of the data displayed under the link provided lies entirely with the Unified Patent Court.
Lapses during opposition  TooltipHU30.06.2008
AT18.12.2019
CY18.12.2019
CZ18.12.2019
DK18.12.2019
EE18.12.2019
ES18.12.2019
FI18.12.2019
HR18.12.2019
IT18.12.2019
LT18.12.2019
LV18.12.2019
MC18.12.2019
MT18.12.2019
NL18.12.2019
PL18.12.2019
RO18.12.2019
SE18.12.2019
SI18.12.2019
SK18.12.2019
TR18.12.2019
BG18.03.2020
NO18.03.2020
GR19.03.2020
IS18.04.2020
PT13.05.2020
IE30.06.2020
LU30.06.2020
[2022/27]
Former [2022/26]AT18.12.2019
CZ18.12.2019
DK18.12.2019
EE18.12.2019
ES18.12.2019
FI18.12.2019
HR18.12.2019
IT18.12.2019
LT18.12.2019
LV18.12.2019
MC18.12.2019
NL18.12.2019
PL18.12.2019
RO18.12.2019
SE18.12.2019
SI18.12.2019
SK18.12.2019
TR18.12.2019
BG18.03.2020
NO18.03.2020
GR19.03.2020
IS18.04.2020
PT13.05.2020
IE30.06.2020
LU30.06.2020
Former [2021/20]AT18.12.2019
CZ18.12.2019
DK18.12.2019
EE18.12.2019
ES18.12.2019
FI18.12.2019
HR18.12.2019
IT18.12.2019
LT18.12.2019
LV18.12.2019
MC18.12.2019
NL18.12.2019
PL18.12.2019
RO18.12.2019
SE18.12.2019
SI18.12.2019
SK18.12.2019
BG18.03.2020
NO18.03.2020
GR19.03.2020
IS18.04.2020
PT13.05.2020
IE30.06.2020
LU30.06.2020
Former [2021/15]AT18.12.2019
CZ18.12.2019
DK18.12.2019
EE18.12.2019
ES18.12.2019
FI18.12.2019
HR18.12.2019
IT18.12.2019
LT18.12.2019
LV18.12.2019
MC18.12.2019
NL18.12.2019
PL18.12.2019
RO18.12.2019
SE18.12.2019
SI18.12.2019
SK18.12.2019
BG18.03.2020
NO18.03.2020
GR19.03.2020
IS18.04.2020
PT13.05.2020
LU30.06.2020
Former [2021/10]AT18.12.2019
CZ18.12.2019
DK18.12.2019
EE18.12.2019
ES18.12.2019
FI18.12.2019
HR18.12.2019
IT18.12.2019
LT18.12.2019
LV18.12.2019
MC18.12.2019
NL18.12.2019
PL18.12.2019
RO18.12.2019
SE18.12.2019
SI18.12.2019
SK18.12.2019
BG18.03.2020
NO18.03.2020
GR19.03.2020
IS18.04.2020
PT13.05.2020
Former [2020/51]AT18.12.2019
CZ18.12.2019
DK18.12.2019
EE18.12.2019
ES18.12.2019
FI18.12.2019
HR18.12.2019
LT18.12.2019
LV18.12.2019
NL18.12.2019
RO18.12.2019
SE18.12.2019
SI18.12.2019
SK18.12.2019
BG18.03.2020
NO18.03.2020
GR19.03.2020
IS18.04.2020
PT13.05.2020
Former [2020/47]CZ18.12.2019
DK18.12.2019
EE18.12.2019
ES18.12.2019
FI18.12.2019
HR18.12.2019
LT18.12.2019
LV18.12.2019
NL18.12.2019
RO18.12.2019
SE18.12.2019
SK18.12.2019
BG18.03.2020
NO18.03.2020
GR19.03.2020
IS18.04.2020
PT13.05.2020
Former [2020/40]CZ18.12.2019
EE18.12.2019
FI18.12.2019
HR18.12.2019
LT18.12.2019
LV18.12.2019
NL18.12.2019
RO18.12.2019
SE18.12.2019
SK18.12.2019
BG18.03.2020
NO18.03.2020
GR19.03.2020
IS18.04.2020
PT13.05.2020
Former [2020/37]CZ18.12.2019
EE18.12.2019
FI18.12.2019
HR18.12.2019
LT18.12.2019
LV18.12.2019
NL18.12.2019
RO18.12.2019
SE18.12.2019
SK18.12.2019
BG18.03.2020
NO18.03.2020
GR19.03.2020
PT13.05.2020
Former [2020/36]CZ18.12.2019
EE18.12.2019
FI18.12.2019
HR18.12.2019
LT18.12.2019
LV18.12.2019
NL18.12.2019
RO18.12.2019
SE18.12.2019
BG18.03.2020
NO18.03.2020
GR19.03.2020
PT13.05.2020
Former [2020/35]CZ18.12.2019
FI18.12.2019
HR18.12.2019
LT18.12.2019
LV18.12.2019
NL18.12.2019
RO18.12.2019
SE18.12.2019
BG18.03.2020
NO18.03.2020
GR19.03.2020
Former [2020/33]FI18.12.2019
HR18.12.2019
LT18.12.2019
LV18.12.2019
NL18.12.2019
SE18.12.2019
BG18.03.2020
NO18.03.2020
GR19.03.2020
Former [2020/25]FI18.12.2019
HR18.12.2019
LT18.12.2019
LV18.12.2019
SE18.12.2019
BG18.03.2020
NO18.03.2020
GR19.03.2020
Former [2020/23]FI18.12.2019
LT18.12.2019
LV18.12.2019
SE18.12.2019
BG18.03.2020
NO18.03.2020
GR19.03.2020
Former [2020/22]FI18.12.2019
LT18.12.2019
SE18.12.2019
BG18.03.2020
NO18.03.2020
Former [2020/21]NO18.03.2020
Documents cited:Search[XP]WO2007139929  (BURNHAM INST MEDICAL RESEARCH [US], et al) [XP] 1-7,10,12-15 * example 1 * * page 17, line 9 - line 16 * * page 18, line 8 - page 19, line 9 *;
 [XP]EP1873237  (MILLIPORE CORP [US]) [XP] 2,3,5-10,14 * paragraph [0040] - paragraph [0042] *;
 [XY]  - KLIMANSKAYA ININA ET AL, "Human embryonic stem cells derived without feeder cells", LANCET (NORTH AMERICAN EDITION), (200505), vol. 365, no. 9471, ISSN 0140-6736, pages 1636 - 1641, XP009076953 [X] 1-7,10,14,15 * page 365, column R - page 367, column L * [Y] 8,9

DOI:   http://dx.doi.org/10.1016/S0140-6736(05)66473-2
 [XY]  - ELLESTROM C ET AL, "Facilitated expansion of human embryonic stem cells by single-cell enzymaticdissociation", STEM CELLS, ALPHAMED PRESS, DAYTON, OH, US, (20070322), vol. 25, no. 7, ISSN 1066-5099, pages 1690 - 1696, XP008081910 [X] 2-7,14,15 * page 1691, column L * [Y] 8,9

DOI:   http://dx.doi.org/10.1634/stemcells.2006-0607
 [X]  - XU CHUNHUI ET AL, "Feeder-free growth of undifferentiated human embryonic stem cells", NATURE BIOTECHNOLOGY, NATURE PUBLISHING GROUP, NEW YORK, NY, US, (20011001), vol. 19, no. 10, ISSN 1087-0156, pages 971 - 974, XP002282070 [X] 1-4,10-15 * page 972, column R - page 973, column R *

DOI:   http://dx.doi.org/10.1038/nbt1001-971
 [X]  - PANCHISION DAVID M ET AL, "Optimized flow cytometric analysis of central nervous system tissue reveals novel functional relationships among cells expressing CD133, CD15, and CD24", STEM CELLS (MIAMISBURG), (200706), vol. 25, no. 6, ISSN 1066-5099, pages 1560 - 1570, XP002496165 [X] 2-6,8-10,12,14 * the whole document *

DOI:   http://dx.doi.org/10.1634/stemcells.2006-0260
 [X]  - SHACKLETON M ET AL, "Generation of a functional mammary gland from a single stem cell", NATURE: INTERNATIONAL WEEKLY JOURNAL OF SCIENCE, NATURE PUBLISHING GROUP, UNITED KINGDOM, (20060105), vol. 439, no. 7072, doi:10.1038/NATURE04372, ISSN 0028-0836, pages 84 - 88, XP002567665 [X] 1,2,5-7,15 * the whole document *

DOI:   http://dx.doi.org/10.1038/nature04372
 [XP]  - BRAAM STEFAN R ET AL, "Improved genetic manipulation of human embryonic stem cells.", NATURE METHODS MAY 2008, (200805), vol. 5, no. 5, ISSN 1548-7105, pages 389 - 392, XP009105761 [XP] 1-6,10-15 * the whole document *

DOI:   http://dx.doi.org/10.1038/NMETH.1200
 [Y]  - "Preserve the stability of your stem cells", (2006), INTERNET CITATION, URL: http://invitrogen.com./etc/medialib/en/filelibrary/pdf.Par.96037.File.dat/F-066598%20TrypLE%20Flyer.pdf, (20080913), XP002496166 [Y] 8,9 * the whole document *
ExaminationWO2006020919
by applicantWO2005014799
 US6642048
 US2002072117
 US2005148070
 US2005233446
 US6800480
 US2005244962
 WO2005065354
 WO2005086845
 US2005158852
 US5843780
 US2007010011
 WO2007030870
 US6458589
 US5770417
 US6022743
 US5567612
 US5759830
 US6626950
 US6534084
 US6306424
 US6365149
 US6599323
 US6656488
 US2004062753
 US4557264
 US6333029
 US6509369
 US6793945
 US6331298
 US2004220393
 US2004209901
 US2004171623
    - REUBINOFF ET AL., NATURE BIOTECHNOLOGY, (2000), vol. 18, pages 399 - 404
    - THOMPSON ET AL., SCIENCE, (19981106), vol. 282, no. 5391, pages 1145 - 1147
    - RICHARDS, STEM CELLS, (2003), vol. 21, pages 546 - 556
    - WANG ET AL., STEM CELLS, (2005), vol. 23, pages 1221 - 1227
    - XU ET AL., STEM CELLS, (2004), vol. 22, pages 972 - 980
    - STOJKOVIC ET AL., STEM CELLS, (2005), vol. 23, pages 306 - 314
    - MIYAMOTO ET AL., STEM CELLS, (2004), vol. 22, pages 433 - 440
    - AMIT ET AL., BIOL. REPROD, (2003), vol. 68, pages 2150 - 2156
    - INZUNZA ET AL., STEM CELLS, (2005), vol. 23, pages 544 - 549
    - LEVENSTEIN ET AL., STEM CELLS, (2006), vol. 24, pages 568 - 574
    - STEM CELLS AND DEVELOPMENT, (2007), vol. 16, no. 1, pages 109 - 118
    - SIDHU, KS ET AL., STEM CELLS DEV., (200602), vol. 15, no. 1, pages 61 - 9
    - DRAPER JS ET AL., "karytypic changes involving the gain of chromosome 17q in three independent human embryonic stem cell lines on five independent occasions", NAT BIOTECHNOL., (20031207), vol. 22, no. 1, pages 53 - 4
    - NAT BIOTECHNOL., (200404), vol. 22, no. 4, pages 381 - 2
    - NAT BIOTECHNOL., (200501), vol. 23, no. 1, pages 19 - 20
    - BIOTECHNOLOGY AND APPLIED BIOCHEMISTRY, (2007), vol. 47, no. 1, pages 33 - 37
    - STEM CELLS, (20060824), vol. 24, no. 12, pages 2649 - 60
    - SCIENCE, (1998), vol. 282, page 1145
    - CURR. TOP. DEV. BIOL., (1998), vol. 38, page 133
    - PROC. NATL. ACAD. SCI. U.S.A., (1995), vol. 92, page 7844
    - D'AMOUR, NATURE BIOTECHNOLOGY, (2005), vol. 23, pages 1534 - 1541
    - SHINOZAKI ET AL., DEVELOPMENT, (2004), vol. 131, pages 1651 - 1662
    - MCLEAN, STEM CELLS, (2007), vol. 25, pages 29 - 38
    - D'AMOUR, NATURE BIOTECHNOLOGY, (2006), vol. 24, pages 1392 - 1401
    - NATURE BIOTECHNOLOGY, (2006), vol. 24, pages 1392 - 1401
    - BAETGE, EE ET AL., NATURE BIOTECHNOLOGY, (2006), vol. 24, no. 11, pages 1392 - 1401
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