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Extract from the Register of European Patents

EP About this file: EP2574930

EP2574930 - Method and biomarker for evaluating metastasis, and siRNA compound for inhibiting metastasis [Right-click to bookmark this link]
StatusThe application has been withdrawn
Status updated on  07.04.2017
Database last updated on 20.09.2024
FormerExamination is in progress
Status updated on  13.01.2017
Most recent event   Tooltip07.04.2017Withdrawal of applicationpublished on 10.05.2017  [2017/19]
Applicant(s)For all designated states
National Cheng Kung University
No. 1, University Road
Tainan City 701 / TW
[2013/14]
Inventor(s)01 / Liao, Pao-Chi
No. 1 University Road
Tainan City 701 / TW
02 / Cheng, Hung-Chi
8F.-2, No.245, Shengxue Road
Yongkang Dist.
Tainan City 710 / TW
03 / Chang, Ying-Hwa
7F., No.108, Sec. 1
Jinshan S. Rd.
Taipei City 100 / TW
04 / Lee, Shu-Hui
No.9, Aly. 23, Ln.
105, Zhongzheng Rd.
Hutatan Township
Changhua County 503 / TW
 [2013/14]
Representative(s)Rigby, Barbara Nicole
Dehns
St Bride's House
10 Salisbury Square
London EC4Y 8JD / GB
[N/P]
Former [2013/14]Leathley, Anna Elisabeth
Dehns St Bride's House 10 Salisbury Square London
EC4Y 8JD / GB
Application number, filing date12182622.631.08.2012
[2013/14]
Priority number, dateUS201161530003P01.09.2011         Original published format: US 201161530003 P
[2013/14]
Filing languageEN
Procedural languageEN
PublicationType: A1 Application with search report 
No.:EP2574930
Date:03.04.2013
Language:EN
[2013/14]
Search report(s)(Supplementary) European search report - dispatched on:EP01.03.2013
ClassificationIPC:G01N33/574
[2013/14]
CPC:
G01N33/574 (EP,US); G01N33/6893 (US); A61P35/00 (EP);
C12N15/113 (EP,US); G01N33/57423 (EP,US); G01N33/57484 (EP,US);
C12N2310/14 (EP,US) (-)
Designated contracting statesAL,   AT,   BE,   BG,   CH,   CY,   CZ,   DE,   DK,   EE,   ES,   FI,   FR,   GB,   GR,   HR,   HU,   IE,   IS,   IT,   LI,   LT,   LU,   LV,   MC,   MK,   MT,   NL,   NO,   PL,   PT,   RO,   RS,   SE,   SI,   SK,   SM,   TR [2013/14]
Extension statesBANot yet paid
MENot yet paid
TitleGerman:Verfahren und Biomarker zur Beurteilung von Metastasen, und siRNA-Verbindung zum Inhibieren von Metastasen[2013/14]
English:Method and biomarker for evaluating metastasis, and siRNA compound for inhibiting metastasis[2013/14]
French:Procédé et biomarqueur pour évaluer des métastases et composé d'ARNsi pour l'inhibition des métastases[2013/14]
Examination procedure25.09.2013Amendment by applicant (claims and/or description)
25.09.2013Examination requested  [2013/45]
12.01.2017Despatch of a communication from the examining division (Time limit: M04)
31.03.2017Application withdrawn by applicant  [2017/19]
Divisional application(s)The date of the Examining Division's first communication in respect of the earliest application for which a communication has been issued is  12.01.2017
Fees paidRenewal fee
19.08.2014Renewal fee patent year 03
18.08.2015Renewal fee patent year 04
19.08.2016Renewal fee patent year 05
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Responsibility for the accuracy, completeness or quality of the data displayed under the link provided lies entirely with the Unified Patent Court.
Documents cited:Search[XY]WO2005061725  (MOUNT SINAI HOSPITAL CORP [CA], et al) [X] 1-12 * page 5, line 21 - line 37; table 1 * [Y] 13-15;
 [Y]EP1752536  (RNAI CO LTD [JP]) [Y] 13-15 * claims 1, 26, 31 *;
    [ ] - "Human alpha-1-antitrypsin precursor DNA.", Geneseq, (20061214), Database accession no. AEL42107, URL: EBI [ ] * sequence . *
 [XI]  - NEJJARI MIMOUN ET AL, "Inhibition of proprotein convertases enhances cell migration and metastases development of human colon carcinoma cells in a rat model", AMERICAN JOURNAL OF PATHOLOGY, (200406), vol. 164, no. 6, ISSN 0002-9440, pages 1925 - 1933, XP002691382 [X] 9-12 * abstract * * page 1925, column r, paragraph l * * page 1928, column r, paragraph 2 - page 1929, column l, paragraph 2 * * page 1931, paragraph l * [I] 13-15

DOI:   http://dx.doi.org/10.1016/S0002-9440(10)63753-4
 [XI]  - B. FAYARD ET AL, "The Serine Protease Inhibitor Protease Nexin-1 Controls Mammary Cancer Metastasis through LRP-1-Mediated MMP-9 Expression", CANCER RESEARCH, (20090715), vol. 69, no. 14, doi:10.1158/0008-5472.CAN-08-4573, ISSN 0008-5472, pages 5690 - 5698, XP055051936 [X] 9-12 * abstract * [I] 13-15

DOI:   http://dx.doi.org/10.1158/0008-5472.CAN-08-4573
 [XI]  - NAGAHARA A ET AL, "SERPINE2 is a possible candidate promotor for lymph node metastasis in testicular cancer", BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS, ACADEMIC PRESS INC. ORLANDO, FL, US, vol. 391, no. 4, doi:10.1016/J.BBRC.2009.12.105, ISSN 0006-291X, (20100122), pages 1641 - 1646, (20100121), XP026863420 [X] 9-12 * abstract * [I] 13-15

DOI:   http://dx.doi.org/10.1016/j.bbrc.2009.12.105
 [XI]  - ARCHANA THAKUR ET AL, "Gene expression profiles in primary pancreatic tumors and metastatic lesions of Ela-c-myc transgenic mice", MOLECULAR CANCER, (20080101), vol. 7, no. 1, doi:10.1186/1476-4598-7-11, ISSN 1476-4598, page 11, XP055051937 [X] 9-12 * abstract * [I] 13-15

DOI:   http://dx.doi.org/10.1186/1476-4598-7-11
 [XI]  - PIERRE MICHAEL ET AL, "Meta-analysis of archived DNA microarrays identifies genes regulated by hypoxia and involved in a metastatic phenotype in cancer cells", BMC CANCER, BIOMED CENTRAL, LONDON, GB, (20100430), vol. 10, no. 1, doi:10.1186/1471-2407-10-176, ISSN 1471-2407, page 176, XP021075015 [X] 9-12 * abstract * [I] 13-15

DOI:   http://dx.doi.org/10.1186/1471-2407-10-176
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