blank Quick help
blank Maintenance news

Scheduled maintenance

Regular maintenance outages:
between 05.00 and 05.15 hrs CET (Monday to Sunday).

Other outages
Availability
Register Forum

2022.02.11

More...
blank News flashes

News flashes

New version of the European Patent Register - SPC information for Unitary Patents.

2024-03-06

More...
blank Related links

Release notes
European Patent Register Assistant
European Patent Register Resource Book
European Patent Register – pocket guide
FAQ - European Patent Register
FAQ - Register Alert
Federated Register (Flyer)
Global Dossier (Flyer)
Register events
Deep link coverage
Federated Register content
The Patent Information Tour
Fair use charter

Extract from the Register of European Patents

EP About this file: EP2586445

EP2586445 - Methods of facilitating cell survival using neurotrophin mimetics [Right-click to bookmark this link]
StatusThe application is deemed to be withdrawn
Status updated on  09.10.2020
Database last updated on 03.06.2024
FormerGrant of patent is intended
Status updated on  04.12.2019
FormerExamination is in progress
Status updated on  23.02.2018
Most recent event   Tooltip09.10.2020Application deemed to be withdrawnpublished on 11.11.2020  [2020/46]
Applicant(s)For all designated states
UNIVERSITY OF NORTH CAROLINA AT CHAPEL HILL
308 Bynum Hall
Chapel Hill, NC 27599-4105 / US
For all designated states
U.S. Government represented by the Department of Veterans Affairs
Office of the General Counsel 810 Vermont Avenue, NW
Washington, DC 20420 / US
[2013/18]
Inventor(s)01 / Longo, Frank, M.
Dept. of Neurology Stanford University
300 Pasteur Drive Room H3160
Standford, CA 94305 / US
02 / Massa, Stephen, M.
120 Newton Drive
Burlingame, CA 94010 / US
[N/P]
Former [2013/18]01 / Longo, Frank, M.
Dept. of Neurology Stanford University
300 Pasteur Drive Room H3160
Standford, CA California 94305 / US
02 / Massa, Stephen, M.
120 Newton Drive
Burlingame, CA California 94010 / US
Representative(s)Isarpatent
Patent- und Rechtsanwälte Barth
Charles Hassa Peckmann & Partner mbB
Friedrichstrasse 31
80801 München / DE
[N/P]
Former [2013/18]Isarpatent
Patent- und Rechtsanwälte
Friedrichstrasse 31
80801 München / DE
Application number, filing date12191674.603.04.2006
[2013/18]
Priority number, dateUS20050671785P15.04.2005         Original published format: US 671785 P
[2013/18]
Filing languageEN
Procedural languageEN
PublicationType: A1 Application with search report 
No.:EP2586445
Date:01.05.2013
Language:EN
[2013/18]
Search report(s)(Supplementary) European search report - dispatched on:EP02.04.2013
ClassificationIPC:A61K31/522, A61P25/00, A61P25/08, A61P25/16, A61P25/28
[2013/18]
CPC:
A61K31/519 (EP,US); A61K31/155 (EP,US); A61K31/445 (EP,US);
A61K31/496 (EP,US); A61K31/497 (EP,US); A61K31/522 (EP,US);
A61K31/537 (EP,US); A61P17/14 (EP); A61P21/02 (EP);
A61P25/00 (EP); A61P25/02 (EP); A61P25/08 (EP);
A61P25/14 (EP); A61P25/16 (EP); A61P25/28 (EP);
A61P3/10 (EP); A61P43/00 (EP); A61P9/00 (EP);
A61P9/10 (EP); C07K16/2878 (EP,US); C07K2317/76 (EP,US) (-)
Designated contracting statesAT,   BE,   BG,   CH,   CY,   CZ,   DE,   DK,   EE,   ES,   FI,   FR,   GB,   GR,   HU,   IE,   IS,   IT,   LI,   LT,   LU,   LV,   MC,   NL,   PL,   PT,   RO,   SE,   SI,   SK,   TR [2013/18]
Extension statesALNot yet paid
BANot yet paid
HRNot yet paid
MKNot yet paid
YUNot yet paid
TitleGerman:Verfahren zur Ermöglichung des Überlebens von Nervenzellen mit Neurotrophin-Mimetika[2013/18]
English:Methods of facilitating cell survival using neurotrophin mimetics[2013/18]
French:Procédés permettant de faciliter la survie de cellules à l'aide de mimétiques de neurotrophine[2013/18]
Examination procedure31.10.2013Amendment by applicant (claims and/or description)
31.10.2013Examination requested  [2013/50]
18.03.2014Despatch of a communication from the examining division (Time limit: M06)
15.09.2014Reply to a communication from the examining division
08.01.2016Despatch of a communication from the examining division (Time limit: M06)
05.07.2016Reply to a communication from the examining division
12.02.2018Despatch of a communication from the examining division (Time limit: M04)
20.06.2018Reply to a communication from the examining division
05.12.2019Communication of intention to grant the patent
03.06.2020Application deemed to be withdrawn, date of legal effect  [2020/46]
26.06.2020Despatch of communication that the application is deemed to be withdrawn, reason: fee for grant / fee for printing not paid in time  [2020/46]
Parent application(s)   TooltipEP06758242.9  / EP1871420
Fees paidRenewal fee
14.02.2013Renewal fee patent year 03
14.02.2013Renewal fee patent year 04
14.02.2013Renewal fee patent year 05
14.02.2013Renewal fee patent year 06
14.02.2013Renewal fee patent year 07
30.04.2013Renewal fee patent year 08
30.04.2014Renewal fee patent year 09
30.04.2015Renewal fee patent year 10
29.04.2016Renewal fee patent year 11
28.04.2017Renewal fee patent year 12
30.04.2018Renewal fee patent year 13
30.04.2019Renewal fee patent year 14
Penalty fee
Additional fee for renewal fee
30.04.202015   M06   Not yet paid
Opt-out from the exclusive  Tooltip
competence of the Unified
Patent Court		 See the Register of the Unified Patent Court for opt-out data
Responsibility for the accuracy, completeness or quality of the data displayed under the link provided lies entirely with the Unified Patent Court.
Documents cited:Search[X]WO8910744  (NAFTCHI N ERIC [US]) [X] 1,2,5-9 * the whole document * * pages 3,9,15 *;
 [X]WO03040096  (ELAN PHARM INC [US], et al) [X] 1,2,5-9 * the whole document * * page 301; compound 1409 *;
 [X]WO03006423  (ELAN PHARM INC [US], et al) [X] 1,2,5-9 * abstract * * pages 22-30 * * page 92; compound 52 *;
 [A]US2002051988  (GILCHREST BARBARA A [US], et al) [A] 1 * abstract *
 [XP]  - S. M. MASSA, "Small, Nonpeptide p75NTR Ligands Induce Survival Signaling and Inhibit proNGF-Induced Death", JOURNAL OF NEUROSCIENCE, (20060517), vol. 26, no. 20, doi:10.1523/JNEUROSCI.3547-05.2006, ISSN 0270-6474, pages 5288 - 5300, XP055057505 [XP] 1-9 * the whole document *

DOI:   http://dx.doi.org/10.1523/JNEUROSCI.3547-05.2006
by applicant   - FAHNESTOCK, M.; MICHALSKI, B.; XU, B.; COUQHLIN, M.D., MOL CELL NEUROSCI, (2001), vol. 18, pages 210 - 220
    - HARRINATON, A.W. ET AL., PROC NATL ACAD SCI USA, (2004), vol. 101, pages 6226 - 6230
    - NYKIAER, A. ET AL., NATURE, (2004), vol. 427, pages 843 - 848
    - MAMIDIPUDI, V.; LI, X.; WOOTEN, M.W., J BIOL CHEM, (2002), vol. 277, pages 28010 - 28018
    - ROUX, P.P.; BHAKAR, A.L.; KENNEDY, T.E.; BARKER, P.A., J BIOL CHEM, (2001), vol. 276, pages 23097 - 23104
    - SALEHI, A.H. ET AL., NEURON, (2000), vol. 27, pages 279 - 288
    - PODULSO, J.F.; CURRAN, G.L., BRAIN RES MOL BRAIN RES, (1996), vol. 36, pages 280 - 286
    - SALTZMAN, W.M.; MAK, M.W.; MAHONEY, M.J.; DUENAS, E.T.; CLELAND, J.L., PHARM RES, (1999), vol. 16, pages 232 - 240
    - PARTRIDQE, W.M., ADV EXP MED BIO, (2002), vol. 513, pages 397 - 430
    - WANQ, J.J.; RABIZADEH, S.; TASINATO, A.; SPERANDIO, S.; YE, X.; GREEN, M.; ASSA-MUNT, N.; SPENCER, D.; BREDESEN, D.E., J NEUROSCI RES, (2000), vol. 60, pages 587 - 593
    - MALIARTCHOUK, S.; DEBEIR, T.; BEQLOVA, N.; CUELLO, A.C.; GEHRINQ, K; SARAGOVI, H. U., J BIOL CHEM, (2000), vol. 275, pages 9946 - 9956
    - LONQO, F.M.; MANTHORPE, M.; XIE, Y.M.; VARON, S., J NEUROSCI RES, (1997), vol. 48, pages 1 - 17
    - HE, X.L.; GARCIA, K.C., SCIENCE, (2004), vol. 304, pages 870 - 875
    - FREIREICH ET AL., CANCER CHEMOTHER REP., (1966), vol. 50, pages 219 - 244
    - ZHOU, HOLTZMAN, D.M.; WEINER, R.I.; MOBLEY, W.C., PROC NATL ACAD SCI USA, (1994), vol. 91, page 3824
    - HUBER, L.J.; CHAO, M.V., DEV BIO, (1995), vol. 167, pages 227 - 238
    - BEATTIE, M.S. ET AL., NEURON, (2002), vol. 36, pages 375 - 386
    - YANQ, T. ET AL., J NEUROSCI, (2003), vol. 23, pages 3353 - 3363
    - LEE, K.F. ET AL., CELL, (1992), vol. 69, pages 737 - 749
    - LONQO F.M.; MANTHORPE, M.; XIE, Y.M.; VARON, S., J NEUROSCI RES, (1997), vol. 48, pages 1 - 17
    - ZHOU, J.; VALLETTA, J.S.; GRIMES, M.L.; MOBLEY, W.C., J NEUROCHEM, (1995), vol. 65, pages 1146 - 1156
    - LONQO, F.M. ET AL., J NEUROSCI RES, (1999), vol. 55, pages 230 - 237
    - HUANG, C.S. ET AL., J BIOL CHEM, (1999), vol. 274, pages 36707 - 36714
    - YOON ET AL., J NEUROSCI, (1998), vol. 18, pages 3273 - 3281
    - HARRINQTON, A.W.; KIM, J.Y.; YOON, S.O., J NEUROSCI, (2002), vol. 22, pages 156 - 166
    - BRANN, A.B. ET AL., J NEUROSCI, (1999), vol. 19, pages 8199 - 8206
    - BUI, N.T. ET AL., J NEUROCHEM, (2002), vol. 81, pages 594 - 605
    - LIPINSKI, C.A., J PHARM TOXICOL METHODS, (2000), vol. 44, pages 235 - 249
    - FU, X.C.; CHEN, C.X.; LIANQ, W.Q.; YU, Q.S., ACTA PHARMACOL SIN, (2001), vol. 22, pages 663 - 668
    - CLARK, D.E., J PHARM SCI, (2002), vol. 88, pages 815 - 821
    - NEUBIQ, R.R.; SPEDDINQ, M; KENAKIN, T.; CHRISTOPOULOS, A., PHARMACOL REV, (2003), vol. 55, pages 597 - 606
    - LACHYANKAR, M.B. ET AL., J NEUROSCI RES, (2003), vol. 71, pages 157 - 172
    - MAMIDIPUDI. V.; LI, X.; WOOTEN, M.W., J BIOL CHEM, (2002), vol. 277, pages 28010 - 28018
    - CARTER, B.D. ET AL., SCIENCE, (1996), vol. 272, pages 542 - 545
    - GENTRY, J.J.; CASACCIA-BONNEFIL, P.; CARTER, B.D., J BIOL CHEM, (2000), vol. 275, pages 7558 - 7565
    - FOEHR, E.D. ET AL., J NEUROSCI RES, (2003), vol. 73, pages 7556 - 7563
    - LAD, S.P.; NEET, K.E., J NEUROSCI RES, (2003), vol. 73, pages 614 - 626
    - SAKURAI, H.; CHIBA, H.; MIYOSHI, H.; SUQITA, T.; TORIUMI, W., J BIOL CHEM, (1999), vol. 274, pages 30353 - 30356
    - LIN, Y.Z.; YAO, S.Y.; VEACH, R.A.; TORQERSON, T.R.; HAWIQER, J., J BIOL CHEM, (1995), vol. 270, pages 14255 - 14258
    - ZHANQ, Y. ET AL., J NEUROSCI, (2003), vol. 23, pages 7385 - 7394
    - LEE, R.; KERMANI, P; TENQ, K.K.; HEMPSTEAD, B.L., SCIENCE, (2001), vol. 294, pages 1945 - 1948
    - CASACCIA-BONNEFIL, P.; CARTER, B.D.; DOBROWSKY, R.T.; CHAO, M.V., NATURE, (1996), vol. 386, pages 716 - 719
    - YOON, S.O.; CASACCIA-BONNEFIL, P.; CARTER, B.; CHAO, M.V., J NEUROSCI, (1998), vol. 18, pages 3273 - 3281
    - NYKIAER, A.; WILLNOW, T.E.; PETERSEN, C.M., CURR OPIN NEUROBIOL, (2005), vol. 15, pages 49 - 57
    - MICHAELIS, M.L. ET AL., J PHARM EXP THER, (2006), vol. 312, pages 659 - 668
    - YANKNER, B.A. ET AL., PNAS, (1990), vol. 87, pages 9020 - 9023
    - WALSH, G.S.; KROL, K.M.; KAWAIA, M.D., J NEUROSCI, (1999), vol. 19, pages 258 - 273
    - APPEL, S. H., ANN NEUROL, (1981), vol. 10, page 499
    - CARTER, B.D. ET AL., SCIENCE, (2002), vol. 272, pages 542 - 545
    - FAHNESTOCK, M.; MICHALSKI, B.; XU, B.; COUGHLIN, M.D., MOL CELL NEUROSCI, (2001), vol. 18, pages 210 - 220
    - FU, X.C.; CHEN, C.X.; LIANG, W.Q.; YU, Q.S., ACTA PHARMACOL SIN, (2001), vol. 22, pages 663 - 668
    - HARRINGTON, A.W. ET AL., PROC NATL ACAD SCI USA, (2004), vol. 101, pages 6226 - 6230
    - HARRINGTON, A.W; KIM, J.Y.; YOON, S.O., J NEUROSCI, (2002), vol. 22, pages 156 - 166
    - HUANG, C.S. ET AL., J BIOL CHEM, (1994), vol. 274, pages 36707 - 36714
    - LEE, R.; KERMANI, P.; TENG, K.K.; HEMPSTEAD, B.L., SCIENCE, (2001), vol. 294, pages 1945 - 1948
    - LIN, Y.Z.; YAO, S.Y.; VEACH, R.A.; TORGERSON, T.R.; HAWIGER, J., J BIOL CHEM, (1995), vol. 270, pages 14255 - 14258
    - LONGO, F.M. ET AL., J NEUROSCI RES, (1999), vol. 55, pages 230 - 237
    - LONGO, F.M.; MANTHORPE, M.; XIE, Y.M.; VARON, S., J NEUROSCI RES, (1997), vol. 48, pages 1 - 17
    - MALIARTCHOUK, S.; DEBEIR, T.; BEGLOVA, N.; CUELLO, A.C.; GEHRING, K; SARAGOVI, H. U., J BIOL CHEM, (2000), vol. 275, pages 9946 - 9956
    - MICHAELIS, M.L.; ANSAR, S.; CHEN, Y.; REIFF, E.R.; SEYB, K.I.; HIMES, R.H.; AUDUS, K.L.; GEORG, G.I., J PHARM EXP THER, (2006), vol. 312, pages 659 - 668
    - NEUBIG, R.R.; SPEDDING, M; KENAKIN, T.; CHRISTOPOULOS, A., PHARMACOL REV, (2003), vol. 55, pages 597 - 606
    - NYKJAER, A. ET AL., NATURE, (2004), vol. 427, pages 843 - 848
    - NYKJAER, A.; WILLNOW, T.E.; PETERSEN, C.M., CURR OPIN NEUROBIOL, (2005), vol. 15, pages 49 - 57
    - PARTRIDGE, W.M., ADV EXP MED BIO, (2002), vol. 513, pages 397 - 430
    - Remington: The Science and Practice of Pharmacy, LIPPINCOTT, WILLIAMS & WILKINS
    - SAKURAI, H.; CHIBA, H.; MIYOSHI, H.; SUGITA, T.; TORIUMI, W., J BIOL CHEM, (1999), vol. 274, pages 30353 - 30356
    - WALSH, G.S.; KROL, K.M.; KAWAJA, M.D., J NEUROSCI, (1999), vol. 19, pages 258 - 273
    - WANG, J.J.; RABIZADEH, S.; TASINATO, A.; SPERANDIO, S.; YE, X.; GREEN, M.; ASSA-MUNT, N.; SPENCER, D.; BREDESEN, D.E., J NEUROSCI RES, (2000), vol. 60, pages 587 - 593
    - YANG, T. ET AL., J NEUROSCI, (2003), vol. 23, pages 3353 - 3363
    - YANKNER, B.A.; CACERES, A.; DUFFY, L.K., PNAS, (1990), vol. 87, pages 9020 - 9023
    - ZHANG, Y. ET AL., J NEUROSCI, (2003), vol. 23, pages 7385 - 7394
    - ZHOU, J.; HOLTZMAN, D.M.; WEINER, R.I.; MOBLEY, W.C., PROC NATL ACAD SCI USA, (1994), vol. 91, page 3824
The EPO accepts no responsibility for the accuracy of data originating from other authorities; in particular, it does not guarantee that it is complete, up to date or fit for specific purposes.