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Extract from the Register of European Patents

EP About this file: EP2683385

EP2683385 - 2,4 SUBSTITUTED PYRIMIDINEDIAMINES FOR USE IN DISCOID LUPUS [Right-click to bookmark this link]
Former [2014/03]2,4 SUBSTITUTED PYRIMIDINEDIAMINES FOR USE IN DISCOID LUPUS
[2018/04]
StatusNo opposition filed within time limit
Status updated on  12.04.2019
Database last updated on 11.09.2024
FormerThe patent has been granted
Status updated on  04.05.2018
FormerGrant of patent is intended
Status updated on  28.01.2018
FormerExamination is in progress
Status updated on  21.12.2016
Most recent event   Tooltip12.04.2019No opposition filed within time limitpublished on 15.05.2019  [2019/20]
Applicant(s)For all designated states
Rigel Pharmaceuticals, Inc.
1180 Veterans Boulevard
South San Francisco, CA 94080 / US
[2014/03]
Inventor(s)01 / MAGILAVY, Daniel
1933 Laguna Street
San Francisco, CA 94115 / US
02 / PINE, Polly
786 Partridge Ave.
Menlo Park, CA 94025 / US
 [2014/03]
Representative(s)J A Kemp LLP
80 Turnmill Street
London EC1M 5QU / GB
[N/P]
Former [2018/23]J A Kemp
14 South Square
Gray's Inn
London WC1R 5JJ / GB
Former [2014/03]Sexton, Jane Helen
J A Kemp
14 South Square
Gray's Inn
London WC1R 5JJ / GB
Application number, filing date12711500.409.03.2012
[2018/23]
WO2012US28429
Priority number, dateUS201161451531P10.03.2011         Original published format: US 201161451531 P
[2014/03]
Filing languageEN
Procedural languageEN
PublicationType: A1 Application with search report
No.:WO2012122452
Date:13.09.2012
Language:EN
[2012/37]
Type: A1 Application with search report 
No.:EP2683385
Date:15.01.2014
Language:EN
The application published by WIPO in one of the EPO official languages on 13.09.2012 takes the place of the publication of the European patent application.
[2014/03]
Type: B1 Patent specification 
No.:EP2683385
Date:06.06.2018
Language:EN
[2018/23]
Search report(s)International search report - published on:EP13.09.2012
ClassificationIPC:A61K31/505, A61P17/00
[2018/04]
CPC:
C07D239/48 (EP,US); A61K31/505 (EP,KR,US); A61K31/506 (KR);
A61K45/06 (EP,US); A61K9/0014 (EP,US); A61P17/00 (EP);
A61P19/04 (EP); A61P37/02 (EP) (-)
C-Set:
A61K31/505, A61K2300/00 (EP,US)
Former IPC [2014/03]A61K31/506, A61P17/00
Designated contracting statesAL,   AT,   BE,   BG,   CH,   CY,   CZ,   DE,   DK,   EE,   ES,   FI,   FR,   GB,   GR,   HR,   HU,   IE,   IS,   IT,   LI,   LT,   LU,   LV,   MC,   MK,   MT,   NL,   NO,   PL,   PT,   RO,   RS,   SE,   SI,   SK,   SM,   TR [2014/03]
Extension statesBANot yet paid
MENot yet paid
TitleGerman:2,4 SUBSTITUTIERTE PYRIMIDINEDIAMINE ZUR VERWENDUNG BEI DISCOIDEM LUPUS[2018/04]
English:2,4 SUBSTITUTED PYRIMIDINEDIAMINES FOR USE IN DISCOID LUPUS[2018/04]
French:PYRIMIDINEDIAMINES 2,4 SUBSTITUTIÉS POUR L'UTILISATION DANS LUPUS CHRONIQUE[2018/04]
Former [2014/03]2,4-SUBSTITUIERTE PYRIMIDINDIAMINE ZUR VERWENDUNG BEI DISKOIDEM LUPUS
Former [2014/03]2,4 SUBSTITUTED PYRIMIDINEDIAMINES FOR USE IN DISCOID LUPUS
Former [2014/03]PYRIMIDINEDIAMINES 2,4-SUBSTITUÉES POUR APPLICATION AU TRAITEMENT DU LUPUS DISCOÏDE
Entry into regional phase07.10.2013National basic fee paid 
07.10.2013Designation fee(s) paid 
07.10.2013Examination fee paid 
Examination procedure07.10.2013Examination requested  [2014/03]
28.04.2014Amendment by applicant (claims and/or description)
17.06.2016Despatch of a communication from the examining division (Time limit: M06)
19.12.2016Reply to a communication from the examining division
29.01.2018Communication of intention to grant the patent
25.04.2018Fee for grant paid
25.04.2018Fee for publishing/printing paid
25.04.2018Receipt of the translation of the claim(s)
Divisional application(s)The date of the Examining Division's first communication in respect of the earliest application for which a communication has been issued is  17.06.2016
Opposition(s)07.03.2019No opposition filed within time limit [2019/20]
Fees paidRenewal fee
27.03.2014Renewal fee patent year 03
27.03.2015Renewal fee patent year 04
31.03.2016Renewal fee patent year 05
27.03.2017Renewal fee patent year 06
27.03.2018Renewal fee patent year 07
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See the Register of the Unified Patent Court for opt-out data
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Cited inInternational search[X]US7491732  (LI HUI [US], et al) [X] 1-8 * claims 1,4 * * column 104, lines 9-25 * * column 113, lines 8, 48, 45 * * column 115, line 48 * * examples 41-44 *;
 [XI]  - CHANG B Y ET AL, "JAK3 inhibition significantly attenuates psoriasiform skin inflammation in CD18 mutant PL/J mice", JOURNAL OF IMMUNOLOGY 20090801 AMERICAN ASSOCIATION OF IMMUNOLOGISTS USA LNKD- DOI:10.4049/JIMMUNOL.0804063, (20090801), vol. 183, no. 3, ISSN 0022-1767, pages 2183 - 2192, XP055025639 [X] 13-15 * abstract * * page 2183, columns r-h, paragraph 2 * * page 2184, columns l-h, paragraph 1 and 2 * * "Results"; page 2185, columns l-h, paragraph l - page 2191, columns l-h, paragraph 1; figures 1-6; tables I-III * * Materials and Methods; page 2184, columns l-h; figures 3A-3E * * "Discussion"; page 2191, columns l-h, paragraph 2 - page 2192, columns l-h, paragraph 1 * [I] 1-12,16-25

DOI:   http://dx.doi.org/10.4049/jimmunol.0804063
Examination   - Paolo Fabbri ET AL, "Cutaneous lupus erythematosus Scientific editor: Prof Benvenuto Giannotti", (20040101), URL: https://www.orpha.net/data/patho/GB/uk-Cutaneous-lupus-erythematosus.pdf, (20160609), XP055279452
by applicantUS4256108
 US4166452
 US4265874
 US7491732
 US2007203161
 US296006
 US6010715
 US5591767
 US5008110
 US5683712
 US5948433
 US5965154
    - ROTHFIELD ET AL., CLINICS IN DERMATOLOGY, (2006), vol. 24, pages 348 - 362
    - "General Principles", FINGL; WOODBURY, Goodman and Gilman's 1he Pharmaceutical Basis of therapeutics, PERGAMON PRESS, pages 1 - 46
    - REMINGTON, The Science and Practice of Pharmacy(21" edition), (2006), pages 872 - 882
    - GHOREISHI; DUTZ, LUPUS, (2010), vol. 19, pages 1029 - 1035
    - FURUKAWA; YOSHIMASU, AUTOIMMUNITY REVIEWS, (2005), vol. 4, pages 345 - 350
    - GUIDUCCI ET AL., JOURNAL OF EXPERIMENTAL MEDICINE, (2010), vol. 207, pages 2931 - 2942
    - A Fonnulary of Cosmetic Preparations (Vol. 2)--Creams, Lotions and Milks, MICELLE PRESS, (1993), vol. 2
    - "oils and gels", ANTHONY L. L. HUNTING, A Fonnulary of Cosmetic Preparations, pages 5 - 14
    - "bases and emulsions", ANTHONY L. L. HUNTING, A Fonnulary of Cosmetic Preparations, pages 15 - 98
    - "ll-purpose products", ANTHONY L. L. HUNTING, A Fonnulary of Cosmetic Preparations, pages 101 - 120
    - "cleansing masks, creams, lotions", ANTHONY L. L. HUNTING, A Fonnulary of Cosmetic Preparations, pages 121 - 184
    - "foundation, vanishing and day creams", ANTHONY L. L. HUNTING, A Fonnulary of Cosmetic Preparations, pages 185 - 208
    - "emollients", ANTHONY L. L. HUNTING, A Fonnulary of Cosmetic Preparations, pages 209 - 254
    - "facial treatment products", ANTHONY L. L. HUNTING, A Fonnulary of Cosmetic Preparations, pages 297 - 324
    - "hand products", ANTHONY L. L. HUNTING, A Fonnulary of Cosmetic Preparations, pages 325 - 380
    - "body and skin creams and lotions", ANTHONY L. L. HUNTING, A Fonnulary of Cosmetic Preparations, pages 381 - 460
    - "baby products", ANTHONY L. L. HUNTING, A Fonnulary of Cosmetic Preparations, pages 461 - 484
The EPO accepts no responsibility for the accuracy of data originating from other authorities; in particular, it does not guarantee that it is complete, up to date or fit for specific purposes.