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Extract from the Register of European Patents

EP About this file: EP2714740

EP2714740 - NEUTRALIZING PROLACTIN RECEPTOR ANTIBODY MAT3 AND ITS THERAPEUTIC USE [Right-click to bookmark this link]
StatusNo opposition filed within time limit
Status updated on  03.02.2017
Database last updated on 11.09.2024
Most recent event   Tooltip03.02.2017No opposition filed within time limitpublished on 08.03.2017  [2017/10]
Applicant(s)For all designated states
Bayer Intellectual Property GmbH
Alfred-Nobel-Strasse 10
40789 Monheim / DE
[2014/15]
Inventor(s)01 / FREIBERG, Christoph
Lipkenskothen 10
42113 Wuppertal / DE
02 / OTTO, Christiane
Jägerstrasse 2
42117 Wuppertal / DE
03 / LINDEN, Lars
Bruchstr. 72
40235 Düsseldorf / DE
04 / HARRENGA, Axel
Sadowastr. 17
42115 Wuppertal / DE
05 / TRAUTWEIN, Mark
Narzissenweg 4
42489 Wülfrath / DE
06 / GREVEN, Simone
Am Schneckenacker 45
41541 Dormagen / DE
07 / WILMEN, Andreas
Arndtstr. 5
50676 Köln / DE
 [2014/15]
Representative(s)BIP Patents
c/o Bayer Intellectual Property GmbH
Alfred-Nobel-Straße 50
40789 Monheim am Rhein / DE
[N/P]
Former [2016/13]BIP Patents
c/o Bayer Intellectual Property GmbH
Alfred-Nobel-Straße 10
40789 Monheim am Rhein / DE
Former [2014/15]BIP Patents
c/o Bayer Intellectual Property GmbH
Creative Campus Monheim
Alfred-Nobel-Straße 10
40789 Monheim / DE
Application number, filing date12729030.231.05.2012
[2016/13]
WO2012EP60078
Priority number, dateEP2011016864403.06.2011         Original published format: EP 11168644
[2014/15]
Filing languageEN
Procedural languageEN
PublicationType: A1 Application with search report
No.:WO2012163932
Date:06.12.2012
Language:EN
[2012/49]
Type: A1 Application with search report 
No.:EP2714740
Date:09.04.2014
Language:EN
The application published by WIPO in one of the EPO official languages on 06.12.2012 takes the place of the publication of the European patent application.
[2014/15]
Type: B1 Patent specification 
No.:EP2714740
Date:30.03.2016
Language:EN
[2016/13]
Search report(s)International search report - published on:EP06.12.2012
ClassificationIPC:C07K16/28, A61K39/395, A61P5/00
[2014/15]
CPC:
C07K16/2869 (EP,US); C07K16/28 (KR); A61K39/395 (KR);
A61K39/3955 (US); A61K45/06 (US); A61P13/08 (EP);
A61P15/00 (EP); A61P15/18 (EP); A61P17/14 (EP);
A61P35/00 (EP); A61P5/00 (EP); A61P5/08 (EP);
C07K16/3015 (US); A61K2039/505 (EP,US); C07K2317/21 (EP,US);
C07K2317/33 (EP,US); C07K2317/34 (EP,US); C07K2317/565 (US);
C07K2317/73 (EP,US); C07K2317/76 (US); C07K2317/92 (EP,US) (-)
Designated contracting statesAL,   AT,   BE,   BG,   CH,   CY,   CZ,   DE,   DK,   EE,   ES,   FI,   FR,   GB,   GR,   HR,   HU,   IE,   IS,   IT,   LI,   LT,   LU,   LV,   MC,   MK,   MT,   NL,   NO,   PL,   PT,   RO,   RS,   SE,   SI,   SK,   SM,   TR [2014/15]
Extension statesBA03.01.2014
ME03.01.2014
TitleGerman:NEUTRALISIERENDER PROLACTINREZEPTOR-ANTIKÖRPER MAT3 UND SEINE THERAPEUTISCHE VERWENDUNG[2014/15]
English:NEUTRALIZING PROLACTIN RECEPTOR ANTIBODY MAT3 AND ITS THERAPEUTIC USE[2014/15]
French:ANTICORPS NEUTRALISANT LE RÉCEPTEUR DE LA PROLACTINE MAT3 ET USAGE THÉRAPEUTIQUE ASSOCIÉ[2014/15]
Entry into regional phase03.01.2014National basic fee paid 
03.01.2014Designation fee(s) paid 
03.01.2014Examination fee paid 
Examination procedure03.01.2014Examination requested  [2014/15]
24.07.2014Amendment by applicant (claims and/or description)
08.10.2014Despatch of a communication from the examining division (Time limit: M06)
24.03.2015Reply to a communication from the examining division
16.04.2015Despatch of a communication from the examining division (Time limit: M04)
20.07.2015Reply to a communication from the examining division
26.10.2015Communication of intention to grant the patent
21.01.2016Fee for grant paid
21.01.2016Fee for publishing/printing paid
21.01.2016Receipt of the translation of the claim(s)
Divisional application(s)The date of the Examining Division's first communication in respect of the earliest application for which a communication has been issued is  08.10.2014
Opposition(s)03.01.2017No opposition filed within time limit [2017/10]
Fees paidRenewal fee
16.05.2014Renewal fee patent year 03
12.05.2015Renewal fee patent year 04
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Patent Court
See the Register of the Unified Patent Court for opt-out data
Responsibility for the accuracy, completeness or quality of the data displayed under the link provided lies entirely with the Unified Patent Court.
Lapses during opposition  TooltipSM30.03.2016
[2016/50]
Cited inInternational search[AD]US2007269438  (ELENBAAS BRIAN [US], et al) [AD] 1-26 * example - *;
 [AD]WO2008022295  (NOVARTIS AG [CH], et al) [AD] 1-26 * example - *;
 [AD]  - J. SISSOM ET AL., "Anti-growth action on mouse mammary and prostate glands of a monoclonal antibody to prolactin receptor.", AMERICAN JOURNAL OF PATHOLOGY, U.S.A., (198812), vol. 133, no. 3, pages 589 - 595, XP008068076 [AD] 1-26 * abstract *
 [A]  - J. SISSOM-DEMORE ET AL., "A monoclonal antibody to prolactin receptor inhibits proliferation of breast cancer cells.", THE FASEB JOURNAL, U.S.A., (19960606), vol. 10, no. 6, page A1389, XP008113243 [A] 1-26 * abstract 2244 *
by applicantUS4399216
 US4510245
 US4634665
 US4657760
 US4816567
 US4968615
 US5168062
 US5179017
 US5206344
 US5225212
 US5766886
 US6300064
 WO03004989
 WO03008583
 US6989250
 WO2006110585
 US2007269438
 WO2008022295
    - BIOESSAYS, (2006), vol. 28, pages 1051 - 1055
    - ENDOCRINE REVIEWS, (1998), vol. 19, pages 225 - 268
    - ANNU. REV. PHYSIOL., (2002), vol. 64, pages 47 - 67
    - NATURE CLINICAL PRACTICE ENDOCRINOLOGY AND METABOLISM, (2006), vol. 2, no. 10, pages 571 - 581
    - BREAST CANCER RES. TREAT., (1989), vol. 14, pages 289 - 29
    - LUPUS, (1998), vol. 7, pages 414 - 419
    - AM J PATHOL, (1988), vol. 133, pages 589 - 595
    - ACTA OBSTET GYNECOL SCAND, (2002), vol. 81, pages 5 - 10
    - RETTER; ALTHAUS HH; MUNCH R; MULLER W, "VBASE2, an integrative V gene database", NUCLEIC ACIDS RES., (20050101), page 33
    - S6DERLIND ET AL., NATURE BIOTECHNOLOGY, (2000), vol. 18, pages 852 - 856
    - ROETHLISBERGER, D. ET AL., J. MOL. BIOL., (2005), vol. 347, pages 773 - 789
    - VIRNEKAS, B.; GE, L.; P ÜCKTHUN, A.; SCHNEIDER, K.C.; WELLNHOFER, G.; MORONEY S.E., "Trinucleotide phosphoramidites: ideal reagents for the synthesis of mixed oligonucleotides for random mutagenesis", NUCL. ACIDS RES., (1994), vol. 22, page 5600
    - KHORANA ET AL., J. MOL. BIOL., (1971), vol. 72, pages 209 - 217
    - URLAUB; CHASIN, PROC. NATL. ACAD. SCI. USA, (1980), vol. 77, pages 4216 - 4220
    - R. J. KAUFMAN; P. A. SHARP, MOL. BIOL., (1982), vol. 159, pages 601 - 621
    - OBSTET. GYNECOL. CLIN. NORTH. AM., (1997), vol. 24, pages 235 - 238
    - HUM. REPROD., (2002), vol. 17, no. 19, pages 2715 - 2724
    - OBSTET. GYNECOL., (1984), vol. 64, pages 151 - 154
    - FERTIL. STERIL., (1998), vol. 69, pages 1042 - 1047
    - BRITISH JOURNAL OF PHARMACOLOGY, (2006), vol. 149, pages 133 - 135
    - LIFE SCIENCES, (1992), vol. 51, pages 1119 - 1125
    - EPIDEMIOL REV, (1997), vol. 19, pages 310 - 327
    - J MAMMARY GLAND BIOL NEOPLASIA, (2005), vol. 10, pages 325 - 335
    - ZENTRALBL GYNäKOL, (1997), vol. 119, pages 54 - 58
    - AM J OBSTET GYNECOL, (1986), vol. 154, pages 161 - 179
    - AM J OBSTET, (1986), vol. 154, pages 161 - 179
    - CLIN ENDOCRINOL, (1985), vol. 23, pages 699 - 704
    - PROC NATL ACAD SCI, (2008), vol. 105, pages 14533 - 14538
    - METHODS IN MAMMARY GLAND BIOLOGY AND BREAST CANCER RESEARCH, (2000), pages 101 - 107
    - GENES DEV, (1997), vol. 11, pages 167 - 178
    - HUMAN REPROD, (2004), vol. 19, pages 1911 - 1916
    - HUMAN REPROD., (2003), vol. 18, pages 2672 - 2677
    - FRONTIERS, NEUROENDOCRINOLOGY, (2001), vol. 22, pages 140 - 145
    - ENDOCRINOLOGY, (1978), vol. 102, pages 1657 - 1661
    - J. CLIN. INVEST., (1997), vol. 99, page 618
    - ENDOCRINOLOGY, (1997), vol. 138, page 4410
    - ENDOCRINOLOGY, (2003), vol. 144, page 2269
    - JAMA, (2002), vol. 233, pages 321 - 333
    - CLEVELAND CLINIC JOURNAL OF MEDICINE, (2009), vol. 76, pages 361 - 367
    - BRITISH JOURNAL OF DERMATOLOGY, (2008), vol. 159, pages 300 - 305
    - AKTUELLE DERMATOLOGIE, (2005), vol. 31, pages 109 - 116
    - J CLIN ENDOCRINOL METAB, (1998), vol. 83, pages 667 - 674
    - INT. J. CANCER, (1993), vol. 55, no. 5, pages 712 - 721
    - CANCER LETT, (2006), vol. 243, pages 160 - 169
    - EUR J SURG ONCOL, (1994), vol. 20, pages 118 - 121
    - J CLIN INVEST, (1997), vol. 100, pages 2744 - 2751
    - PAUL KELLY, PROC NATL ACAD SCI U S A., (2008), vol. 105, no. 38, pages 14533 - 14538
    - SCATCHARD ET AL., ANN N.Y. ACAD. SCL, (1949), vol. 51, page 660
    - LABRIJN ET AL., CURRENT OPINION IN IMMUNOLOGY, (2008), vol. 20, pages 479 - 485
    - SAZINSKY ET AL., PROC. NAT. ACAD. SCI., (2008), vol. 105, no. 51, page 20169
    - SIMMONS ET AL., J. OF IMMUNOLOGICAL METHODS, (2002), vol. 263, pages 133 - 147
    - HEZAREH ET AL., J. OF VIROLOGY, (2001), vol. 75, no. 24, pages 12161 - 12168
    - SCHUURMAN, J. ET AL., IMMUNOLOGY, (1999), vol. 97, pages 693 - 698
    - ALLEN ET, BIOCHEMISTRY, (2009), vol. 48, no. 17, pages 3755 - 3766
    - AN ET AL., MABS, (2009), vol. 1, no. 6
    - KOHLER ET AL., NATURE, (1975), vol. 256, page 495
    - JOHNSON; WU, NUCLEIC ACIDS RES., (2000), vol. 28, pages 214 - 218
    - CHOTHIA ET AL., J. MOL.BIOL., (1987), vol. 196, pages 901 - 917
    - ZAPATA ET AL., PROTEIN ENG., (1995), vol. 8, no. 10, pages 1057 - 1062
    - PLUCKTHUN, The Pharmacology of Monoclonal Antibodies, SPRINGER-VERLAG, (1994), vol. 113, pages 269 - 315
    - CARLSSON; S6DERLIND, EXP. REV. MOL. DIAGN., (2001), vol. 1, no. 1, pages 102 - 108
    - S6DERLIN ET AL., NAT. BIOTECH., (2000), vol. 18, pages 852 - 856
    - KNAPPIK ET AL., J. MOL. BIOL., (2000), vol. 296, page 57
    - KREBS ET AL., J. IMMUNOL. METHODS., (2001), vol. 254, page 67
    - REMINGTON'S PHARMACEUTICAL SCIENCES, MACK PUB. CO., (1990), pages 484 - 528
    - Remington's Pharmaceutical Sciences, MAACK PUBLISHING CO
    - RIVA ET AL., CLIN. CANCER RES., (1999), vol. 5, pages 3275S - 3280S
    - WONG ET AL., CLIN. CANCER RES., (2000), vol. 6, pages 3855 - 3863
    - WAGNER ET AL., J. NUCLEAR MED., (2002), vol. 43, pages 267 - 272
    - ENDOCRINOLGY, (2008), vol. 149, no. 8, pages 3952 - 3959
    - LABORATORY ANIMAL SCIENCE, (1998), vol. 48, pages 64 - 68
    - ENDOCRINOLOGY, (2009), vol. 149, no. 8, pages 3952 - 3959
    - MARKS ET AL., METHODS MOL BIOL., (2004), vol. 248, pages 161 - 76
    - METHODS MOL BIOL., (2004), vol. 248, pages 161 - 76
    - BMC BIOTECHNOLOGY, (2007), vol. 7, page 65
    - TIMMERMAN ET AL., J. MOL. RECOGNIT., (2007), vol. 20, pages 283 - 99
    - PEPSCAN THERAPEUTICS
    - SLOOTSTRA ET AL., MOLECULAR DIVERSITY, (1996), vol. 1, pages 87 - 96
    - "Expressing complex relationships in two dimensions", Interpreting Multivariate Data, JOHN WILEY & SONS, pages 83 - 118
    - Human Antibody Capture Kit, GE HEALTHCARE BIACORE, INC.
The EPO accepts no responsibility for the accuracy of data originating from other authorities; in particular, it does not guarantee that it is complete, up to date or fit for specific purposes.