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Extract from the Register of European Patents

EP About this file: EP2726592

EP2726592 - STABILIZED SUBTILISIN COMPOSITION [Right-click to bookmark this link]
StatusOpposition rejected
Status updated on  25.06.2021
Database last updated on 09.04.2026
FormerThe patent has been granted
Status updated on  02.01.2018
Most recent event   Tooltip25.06.2021Opposition rejectedpublished on 28.07.2021  [2021/30]
Applicant(s)For all designated states
Novozymes A/S
Krogshoejvej 36
2880 Bagsvaerd / DK
[2014/19]
Inventor(s)01 / MIKKELSEN, Lise, Munch
Lysbrovej 34
DK-2610 Roedovre / DK
02 / PONZINI, Francesco
Foscolo 36
I-20094 Corsico (MI) / IT
03 / BISACCIA, Roberto
via Monasterolo 3
I-24039 Sotto il Monte Giovanni XXIII (BG) / IT
04 / CANEVOTTI, Renato
via Adda 13
I-20863 Concorezzo (MB) / IT
 [2014/19]
Representative(s)Potter Clarkson
Chapel Quarter
Mount Street
Nottingham NG1 6HQ / GB
[N/P]
Application number, filing date12733657.629.06.2012
WO2012EP62760
Priority number, dateEP2011017235701.07.2011         Original published format: EP 11172357
[2014/19]
Filing languageEN
Procedural languageEN
PublicationType: A1 Application with search report
No.:WO2013004636
Date:10.01.2013
Language:EN
[2013/02]
Type: A1 Application with search report 
No.:EP2726592
Date:07.05.2014
Language:EN
The application published by WIPO in one of the EPO official languages on 10.01.2013 takes the place of the publication of the European patent application.
[2014/19]
Type: B1 Patent specification 
No.:EP2726592
Date:01.04.2015
Language:EN
[2015/14]
Search report(s)International search report - published on:EP10.01.2013
ClassificationIPC:C11D3/386, C07K5/06, C07K5/08
[2014/19]
CPC:
C11D3/38663 (EP,CN,RU,US); C11D3/38618 (CN,RU,US); C07K5/06026 (EP,CN,RU,US);
C07K5/06043 (EP,CN,RU,US); C07K5/06052 (EP,CN,RU,US); C07K5/06078 (EP,CN,RU,US);
C07K5/06095 (EP,CN,RU,US); C07K5/0808 (EP,CN,RU,US); C07K5/0812 (EP,CN,RU,US);
Y02P20/55 (EP,US) (-)
Designated contracting statesAL,   AT,   BE,   BG,   CH,   CY,   CZ,   DE,   DK,   EE,   ES,   FI,   FR,   GB,   GR,   HR,   HU,   IE,   IS,   IT,   LI,   LT,   LU,   LV,   MC,   MK,   MT,   NL,   NO,   PL,   PT,   RO,   RS,   SE,   SI,   SK,   SM,   TR [2014/19]
Extension statesBANot yet paid
MENot yet paid
TitleGerman:STABILISIERTE SUBTILISINZUSAMMENSETZUNG[2014/19]
English:STABILIZED SUBTILISIN COMPOSITION[2014/19]
French:COMPOSITION DE SUBTILISINE STABILISÉE[2014/19]
Entry into regional phase03.02.2014National basic fee paid 
03.02.2014Designation fee(s) paid 
03.02.2014Examination fee paid 
Examination procedure03.02.2014Examination requested  [2014/19]
03.11.2014Communication of intention to grant the patent
17.02.2015Fee for grant paid
17.02.2015Fee for publishing/printing paid
17.02.2015Receipt of the translation of the claim(s)
Divisional application(s)The date of the Examining Division's first communication in respect of the earliest application for which a communication has been issued is  03.11.2014
Opposition(s)Opponent(s)01  18.12.2015  20.01.2016  ADMISSIBLE
BASF SE
Carl-Bosch-Strasse 38
67056 Ludwigshafen / DE
Opponent's representative
BASF IP Association
BASF SE
G-FLP-C006
67056 Ludwigshafen / DE
 [N/P]
Former [2016/15]
Opponent(s)01  18.12.2015  20.01.2016  ADMISSIBLE
BASF SE
Carl-Bosch-Strasse 38
67056 Ludwigshafen / DE
Opponent's representative
BASF IP Association
BASF SE
ZRX-C6
67056 Ludwigshafen / DE
Former [2016/08]
Opponent(s)01  18.12.2015  20.01.2016  ADMISSIBLE
BASF SE
Carl-Bosch-Strasse 38
67056 Ludwigshafen / DE
Opponent's representative
Sendrowski, Heiko
BASF SE
Global Intellectual Property
GVX/B - C6
Carl-Bosch-Strasse 38
67056 Ludwigshafen / DE
Former [2016/06]
Opponent(s)01  18.12.2015   
BASF SE
Carl-Bosch-Strasse 38
67056 Ludwigshafen / DE
11.02.2016Invitation to proprietor to file observations on the notice of opposition
12.08.2016Reply of patent proprietor to notice(s) of opposition
11.12.2017Date of oral proceedings
03.01.2018Despatch of minutes of oral proceedings
03.01.2018Date of despatch of rejection of opposition
11.05.2021Legal effect of rejection of opposition [2021/30]
Appeal following opposition22.02.2018Appeal received No.  T0539/18
04.05.2018Statement of grounds filed
11.05.2021Result of appeal procedure: appeal of the opponent was rejected
21.06.2021Despatch of the decision of the Board of Appeal
11.05.2021Date of oral proceedings
Fees paidRenewal fee
30.06.2014Renewal fee patent year 03
Opt-out from the exclusive  Tooltip
competence of the Unified
Patent Court		 See the Register of the Unified Patent Court for opt-out data
Responsibility for the accuracy, completeness or quality of the data displayed under the link provided lies entirely with the Unified Patent Court.
Lapses during opposition  TooltipHU29.06.2012
AL01.04.2015
AT01.04.2015
BG01.04.2015
CY01.04.2015
CZ01.04.2015
EE01.04.2015
HR01.04.2015
LT01.04.2015
LV01.04.2015
MC01.04.2015
MK01.04.2015
MT01.04.2015
PL01.04.2015
RO01.04.2015
RS01.04.2015
SE01.04.2015
SI01.04.2015
SK01.04.2015
SM01.04.2015
IE29.06.2015
LU29.06.2015
CH30.06.2015
LI30.06.2015
NO01.07.2015
GR02.07.2015
IS01.08.2015
PT03.08.2015
[2018/46]
Former [2018/31]HU29.06.2012
AT01.04.2015
BG01.04.2015
CY01.04.2015
CZ01.04.2015
EE01.04.2015
HR01.04.2015
LT01.04.2015
LV01.04.2015
MC01.04.2015
MK01.04.2015
MT01.04.2015
PL01.04.2015
RO01.04.2015
RS01.04.2015
SE01.04.2015
SI01.04.2015
SK01.04.2015
SM01.04.2015
IE29.06.2015
LU29.06.2015
CH30.06.2015
LI30.06.2015
NO01.07.2015
GR02.07.2015
IS01.08.2015
PT03.08.2015
Former [2017/39]HU29.06.2012
AT01.04.2015
BG01.04.2015
CY01.04.2015
CZ01.04.2015
EE01.04.2015
HR01.04.2015
LT01.04.2015
LV01.04.2015
MC01.04.2015
MT01.04.2015
PL01.04.2015
RO01.04.2015
RS01.04.2015
SE01.04.2015
SI01.04.2015
SK01.04.2015
SM01.04.2015
IE29.06.2015
LU29.06.2015
CH30.06.2015
LI30.06.2015
NO01.07.2015
GR02.07.2015
IS01.08.2015
PT03.08.2015
Former [2017/03]AT01.04.2015
CZ01.04.2015
EE01.04.2015
HR01.04.2015
LT01.04.2015
LV01.04.2015
MC01.04.2015
MT01.04.2015
PL01.04.2015
RO01.04.2015
RS01.04.2015
SI01.04.2015
SK01.04.2015
IE29.06.2015
LU29.06.2015
CH30.06.2015
LI30.06.2015
NO01.07.2015
GR02.07.2015
IS01.08.2015
PT03.08.2015
Former [2016/24]AT01.04.2015
CZ01.04.2015
EE01.04.2015
HR01.04.2015
LT01.04.2015
LV01.04.2015
MC01.04.2015
PL01.04.2015
RO01.04.2015
RS01.04.2015
SI01.04.2015
SK01.04.2015
IE29.06.2015
LU29.06.2015
CH30.06.2015
LI30.06.2015
NO01.07.2015
GR02.07.2015
IS01.08.2015
PT03.08.2015
Former [2016/22]AT01.04.2015
CZ01.04.2015
EE01.04.2015
HR01.04.2015
LT01.04.2015
LV01.04.2015
MC01.04.2015
PL01.04.2015
RO01.04.2015
RS01.04.2015
SK01.04.2015
IE29.06.2015
LU29.06.2015
CH30.06.2015
LI30.06.2015
NO01.07.2015
GR02.07.2015
IS01.08.2015
PT03.08.2015
Former [2016/20]AT01.04.2015
CZ01.04.2015
EE01.04.2015
HR01.04.2015
LT01.04.2015
LV01.04.2015
MC01.04.2015
PL01.04.2015
RO01.04.2015
RS01.04.2015
SK01.04.2015
IE29.06.2015
LU29.06.2015
NO01.07.2015
GR02.07.2015
IS01.08.2015
PT03.08.2015
Former [2016/10]AT01.04.2015
CZ01.04.2015
EE01.04.2015
HR01.04.2015
LT01.04.2015
LV01.04.2015
MC01.04.2015
PL01.04.2015
RO01.04.2015
RS01.04.2015
SK01.04.2015
LU29.06.2015
NO01.07.2015
GR02.07.2015
IS01.08.2015
PT03.08.2015
Former [2016/09]AT01.04.2015
CZ01.04.2015
EE01.04.2015
HR01.04.2015
LT01.04.2015
LV01.04.2015
MC01.04.2015
RS01.04.2015
NO01.07.2015
GR02.07.2015
IS01.08.2015
PT03.08.2015
Former [2015/51]AT01.04.2015
CZ01.04.2015
HR01.04.2015
LT01.04.2015
LV01.04.2015
RS01.04.2015
NO01.07.2015
GR02.07.2015
IS01.08.2015
PT03.08.2015
Former [2015/50]CZ01.04.2015
HR01.04.2015
LT01.04.2015
LV01.04.2015
RS01.04.2015
NO01.07.2015
GR02.07.2015
IS01.08.2015
PT03.08.2015
Former [2015/49]CZ01.04.2015
HR01.04.2015
LT01.04.2015
LV01.04.2015
RS01.04.2015
NO01.07.2015
GR02.07.2015
PT03.08.2015
Cited inby applicantWO9813458
 WO9404651
 WO9813460
 WO9525791
 WO2009118375
 WO2011036153
 WO9847523
 US6500802
 US5436229
 US4703036
 US4478745
 US5578574
 WO9813459
 WO9813461
 WO9813462
 WO2007141736
 WO2007145963
 WO2010055052
 WO8906279
 WO9318140
 WO9820115
 WO0144452
 WO0158275
 WO0158276
 WO03006602
 WO2004099401
 WO9219729
 WO9820116
 WO9834946
 WO2011036263
 EP0258068
 EP0305216
 WO9613580
 EP0218272
 EP0331376
 GB1372034
 WO9506720
 WO9627002
 WO9612012
 JPS6474992
 WO9116422
 WO9205249
 WO9401541
 EP0407225
 EP0260105
 WO9535381
 WO9600292
 WO9530744
 WO9425578
 WO9514783
 WO9522615
 WO9704079
 WO9707202
 WO0060063
 WO2007087508
 WO2009109500
 GB1296839
 WO9402597
 WO9418314
 WO9623873
 WO9743424
 US6124127
 WO9927083
 WO9927084
 WO0206442
 WO02092741
 WO03095638
 WO9964619
 US4435307
 US5648263
 US5691178
 US5776757
 WO8909259
 EP0495257
 EP0531372
 WO9611262
 WO9629397
 WO9808940
 WO9407998
 EP0531315
 US5457046
 US5686593
 US5763254
 WO9524471
 WO9812307
 WO9901544
 US2009011970
 WO02102955
 US4765916
 US4972017
 US5453216
 US6727215
 WO9817767
 EP0624154
   WHITE; HANDLER; SMITH: "Principles of Biochemistry", 1973, MCGRAW-HILL BOOK COMPANY, pages: 271 - 272
   SIEZEN ET AL., PROTEIN ENGNG., vol. 4, 1991, pages 719 - 737
   SIEZEN ET AL., PROTEIN SCIENCE, vol. 6, 1997, pages 501 - 523
   DARTOIS ET AL., BIOCHEMICA ET BIOPHYSICA ACTA, vol. 1131, 1993, pages 253 - 360
   MARCH: "J. Advanced Organic Chemistry", 1992, WILEY-INTERSCIENCE, pages: 895
   J. AM. CHEM. SOC., vol. 100, 1978, pages 1228
   J. PEPT. SCI., vol. 13, 2007, pages 1 - 15
   SYNTHESIS, 1983, pages 676
   ORG. SYNTH., CO//., vol. 7, pages 361
OppositionWO2011036153
 WO2009118375
 WO2010003934
 WO03083030
 WO9429428
 EP0583534
   BRAYER ET AL.: "crystallographic and kinetic investigations of the covalent coplex formed by a specific tetrapeptide aldehyde and the serine protease from Streptomyces griseus", PROC. NATL. ACAD. SCI. USA, vol. 76, no. 1, January 1979 (1979-01-01), pages 96 - 100, XP055260351
   KIM ET AL.: "Broad spectrum antivirals against 3c or 3c-like proteases of picornaviruses, noroviruses and coronaviruses", JOURNAL OF VIROLOGY, vol. 86, no. 21, 2012, pages 11754 - 11762, XP055188379

DOI:   http://dx.doi.org/10.1128/JVI.01348-12
   GREEN ET AL.: "the PH independent equilibrium constants and rate constants for formation of the bisulfite addition compound of isobutyraldehyde in water", J. ORG. CHEM., vol. 39, no. 26, 1974, pages 3896 - 3901, XP055260369
   KOKESH ET AL.: "a re-examination of the equilibrium addition of bisulfite and sulphite ions to benzaldehyde", J. ORG. CHEM., vol. 40, no. 11, 1975, pages 1632 - 1636, XP055260372
   EXPERIMENTAL REPORT, pages 1 - 3, XP055260375
The EPO accepts no responsibility for the accuracy of data originating from other authorities; in particular, it does not guarantee that it is complete, up to date or fit for specific purposes.