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Extract from the Register of European Patents

EP About this file: EP2665727

EP2665727 - BICYCLIC CARBOXAMIDE INHIBITORS OF KINASES [Right-click to bookmark this link]
StatusThe application is deemed to be withdrawn
Status updated on  07.08.2015
Database last updated on 11.09.2024
Most recent event   Tooltip07.08.2015Application deemed to be withdrawnpublished on 09.09.2015  [2015/37]
Applicant(s)For all designated states
Abbvie Inc.
1 North Waukegan Road
North Chicago, IL 60064 / US
[2013/48]
Inventor(s)01 / VASUDEVAN, Anil
105 13th Avenue
Union Grove WI 53182 / US
02 / PENNING, Thomas Dale
321 Highview
Elmhurst IL 60126 / US
03 / CHEN, Huanming
12 Amargosa
Irvine CA 92602 / US
04 / LIANG, Bo
4-1701, Building 1
Xiangshuwan 2nd Residential Square
Xiaoyingxi Street
Haidian District
Beijing 100085 / CN
05 / WANG, Shaohui
6-401, Building 13
Long Teng Yuan Er Qu
Chang Ping District
Beijing 102208 / CN
06 / WU, Fengchun
3-501, Building 9
Tianluyuan 1
Changping District
Beijing 100028 / CN
07 / SHEN, Yan
3-501, Building 9
Tianluyuan 1
Changping District
Beijing 100028 / CN
08 / LIU, Cuihua
3-401, Building 1
Longzeyuan East
Changping District
Beijing 100028 / CN
09 / ZOU, Zhenguang
8-1-602, Yard 6
Ximachang Road
Fengtai District
Beijing 100068 / CN
10 / PLIUSHCEV, Marina
337 Albert Dr.
Vernon Hills, IL 60062 / US
 [2013/48]
Representative(s)Modiano, Micaela Nadia, et al
Modiano & Partners (DE)
Thierschstrasse 11
80538 München / DE
[2013/48]
Application number, filing date12736701.920.01.2012
WO2012CN00103
Priority number, dateWO2011CN0010921.01.2011         Original published format: PCT/CN2011/000109
[2013/48]
Filing languageEN
Procedural languageEN
PublicationType: A1 Application with search report
No.:WO2012097684
Date:26.07.2012
Language:EN
[2012/30]
Type: A1 Application with search report 
No.:EP2665727
Date:27.11.2013
Language:EN
The application published by WIPO in one of the EPO official languages on 26.07.2012 takes the place of the publication of the European patent application.
[2013/48]
Search report(s)International search report - published on:CN26.07.2012
(Supplementary) European search report - dispatched on:EP16.05.2014
ClassificationIPC:C07D487/04, C07D471/04, A61K31/519, A61K31/4985, A61K31/4353, A61K31/5365, A61P35/00
[2013/48]
CPC:
C07D519/00 (EP,US); A61K31/4353 (EP,US); A61P35/00 (EP);
A61P35/02 (EP); A61P43/00 (EP); C07D471/04 (EP,US);
C07D487/04 (EP,US) (-)
Designated contracting statesAL,   AT,   BE,   BG,   CH,   CY,   CZ,   DE,   DK,   EE,   ES,   FI,   FR,   GB,   GR,   HR,   HU,   IE,   IS,   IT,   LI,   LT,   LU,   LV,   MC,   MK,   MT,   NL,   NO,   PL,   PT,   RO,   RS,   SE,   SI,   SK,   SM,   TR [2013/48]
TitleGerman:BICYCLISCHE CARBOXAMID-KINASE-HEMMER[2013/48]
English:BICYCLIC CARBOXAMIDE INHIBITORS OF KINASES[2013/48]
French:INHIBITEURS DE KINASES À BASE DE CARBOXAMIDES BICYCLIQUES[2013/48]
Entry into regional phase22.07.2013National basic fee paid 
22.07.2013Search fee paid 
22.07.2013Designation fee(s) paid 
22.07.2013Examination fee paid 
Examination procedure22.07.2013Examination requested  [2013/48]
03.03.2014Amendment by applicant (claims and/or description)
16.12.2014Application deemed to be withdrawn, date of legal effect  [2015/37]
06.03.2015Despatch of communication that the application is deemed to be withdrawn, reason: reply to the communication from the examining division not received in time  [2015/37]
Fees paidRenewal fee
08.01.2014Renewal fee patent year 03
Penalty fee
Additional fee for renewal fee
31.01.201504   M06   Not yet paid
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Responsibility for the accuracy, completeness or quality of the data displayed under the link provided lies entirely with the Unified Patent Court.
Documents cited:Search[A]  - ARDINI E ET AL, "Anaplastic Lymphoma Kinase: Role in specific tumours, and development of small molecule inhibitors for cancer therapy", CANCER LETTERS, NEW YORK, NY, US, vol. 299, no. 2, doi:10.1016/J.CANLET.2010.09.001, ISSN 0304-3835, (20101228), pages 81 - 94, (20101028), XP027451190 [A] 1-15 * compound - *

DOI:   http://dx.doi.org/10.1016/j.canlet.2010.09.001
 [A]  - COOPMAN P J P ET AL, "The Syk tyrosine kinase suppresses malignant growth of human breast cancer cells", NATURE, NATURE PUBLISHING GROUP, UNITED KINGDOM, (20000817), vol. 406, doi:10.1038/35021086, ISSN 0028-0836, pages 742 - 747, XP002168402 [A] 1-15 * the whole document *

DOI:   http://dx.doi.org/10.1038/35021086
International search[X]WO2009140128  (IRM LLC [US], et al);
 [X]WO2005009389  (EXELIXIS INC [US], et al);
 [X]WO2006087538  (ASTRAZENECA AB [SE], et al);
 [X]US2009099167  (BOLD GUIDO [CH], et al);
 [X]WO2006106326  (ASTRAZENECA AB [SE], et al);
 [X]WO2006087530  (ASTRAZENECA AB [SE], et al);
 [X]WO2009126514  (IRM LLC [US], et al);
 [X]WO2008144253  (IRM LLC [US], et al);
 [A]JP2004203748  (KISSEI PHARMACEUTICAL);
 [A]JP2004238296  (KISSEI PHARMACEUTICAL);
 [A]  - HIRABAYASHI, A. ET AL., "A novel Syk family kinase inhibitor: Design, synthesis, and structure-activity relationship of 1,2,4-triazolo[4,3-c]pyrimidine and 1,2,4-triazolo[1,5-c]pyrimidine derivatives", BIOORGANIC & MEDICINAL CHEMISTRY, (20080614), vol. 16, no. 15, pages 7347 - 7357, XP023610713

DOI:   http://dx.doi.org/10.1016/j.bmc.2008.06.017
 [A]  - HIRABAYASHI, A. ET AL., "Structure-activity relationship studies of 5-benzylaminoimidazo[1,2-c]pyrimidine-8-carboxamide derivatives as potent, highly selective ZAP-70 kinase inhibitors", BIOORGANIC & MEDICINAL CHEMISTRY, (20081105), vol. 17, no. 1, pages 284 - 294, XP025816121

DOI:   http://dx.doi.org/10.1016/j.bmc.2008.10.070
The EPO accepts no responsibility for the accuracy of data originating from other authorities; in particular, it does not guarantee that it is complete, up to date or fit for specific purposes.