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Extract from the Register of European Patents

EP About this file: EP2737074

EP2737074 - Process for producing L-carnitine from beta-lactones employing lipases [Right-click to bookmark this link]
Former [2014/23]PROCESS FOR PRODUCING L-CARNITINE FROM BETA-LACTONES EMPLOYING LIPASES
[2015/51]
StatusNo opposition filed within time limit
Status updated on  07.04.2017
Database last updated on 05.10.2024
Most recent event   Tooltip12.10.2018Lapse of the patent in a contracting state
New state(s): AL		published on 14.11.2018  [2018/46]
Applicant(s)For all designated states
Lonza Ltd
Lonzastrasse
3930 Visp / CH
[2014/23]
Inventor(s)01 / AVI, Manuela
Schützenstrasse 5
6330 Kufstein / AT
02 / KLEGRAF, Ellen
Apollostrasse 8
CH-3902 Brig-Glis / CH
 [2014/42]
Former [2014/23]01 / AVI, Manuela
Jesuitenweg 168
CH-3902 Brig-Glis / CH
02 / KLEGRAF, Ellen
Apollostrasse 8
CH-3902 Brig-Glis / CH
Representative(s)Riegler, Norbert Hermann
Lonza Ltd.
Patent Department
Münchensteinerstrasse 38
4052 Basel / CH
[2016/22]
Former [2014/23]Riegler, Norbert Hermann
Lonza Ltd. Patent Department Münchensteinerstrasse 38
4052 Basel / CH
Application number, filing date12738462.625.07.2012
[2016/22]
WO2012EP64575
Priority number, dateEP2011000616327.07.2011         Original published format: EP 11006163
US201161512032P27.07.2011         Original published format: US 201161512032 P
[2014/23]
Filing languageEN
Procedural languageEN
PublicationType: A1 Application with search report
No.:WO2013014179
Date:31.01.2013
Language:EN
[2013/05]
Type: A1 Application with search report 
No.:EP2737074
Date:04.06.2014
Language:EN
The application published by WIPO in one of the EPO official languages on 31.01.2013 takes the place of the publication of the European patent application.
[2014/23]
Type: B1 Patent specification 
No.:EP2737074
Date:01.06.2016
Language:EN
[2016/22]
Search report(s)International search report - published on:EP31.01.2013
ClassificationIPC:C12P13/00, C12P7/42, C12P7/62, C12P41/00
[2014/23]
CPC:
C12P13/007 (EP,US); C12P41/005 (EP,US); C12P7/42 (EP,US);
C12P7/62 (EP,US)
Designated contracting statesAL,   AT,   BE,   BG,   CH,   CY,   CZ,   DE,   DK,   EE,   ES,   FI,   FR,   GB,   GR,   HR,   HU,   IE,   IS,   IT,   LI,   LT,   LU,   LV,   MC,   MK,   MT,   NL,   NO,   PL,   PT,   RO,   RS,   SE,   SI,   SK,   SM,   TR [2014/23]
Extension statesBANot yet paid
MENot yet paid
TitleGerman:Verfahren zur Herstellung von L-Carnitin aus beta-Lactonen unter Verwendung von Lipasen[2015/51]
English:Process for producing L-carnitine from beta-lactones employing lipases[2015/51]
French:Procédé de préparation de L-carnitine à partir de beta-lactones en utilisant des lipases[2015/51]
Former [2014/23]VERFAHREN ZUR HERSTELLUNG VON L-CARNITIN AUS BETA-LACTONEN UNTER VERWENDUNG VON LIPASEN
Former [2014/23]PROCESS FOR PRODUCING L-CARNITINE FROM BETA-LACTONES EMPLOYING LIPASES
Former [2014/23]PROCÉDÉ POUR PRODUIRE DE LA L-CARNITINE À PARTIR DE BÊTA-LACTONES EN UTILISANT DES LIPASES
Entry into regional phase27.02.2014National basic fee paid 
27.02.2014Designation fee(s) paid 
27.02.2014Examination fee paid 
Examination procedure12.02.2013Request for preliminary examination filed
International Preliminary Examining Authority: EP
27.02.2014Examination requested  [2014/23]
11.09.2014Amendment by applicant (claims and/or description)
18.02.2015Despatch of a communication from the examining division (Time limit: M06)
06.08.2015Reply to a communication from the examining division
27.11.2015Communication of intention to grant the patent
30.03.2016Disapproval of the communication of intention to grant the patent by the applicant or resumption of examination proceedings by the EPO
04.04.2016Fee for grant paid
04.04.2016Fee for publishing/printing paid
25.04.2016Information about intention to grant a patent
25.04.2016Receipt of the translation of the claim(s)
Divisional application(s)The date of the Examining Division's first communication in respect of the earliest application for which a communication has been issued is  18.02.2015
Opposition(s)02.03.2017No opposition filed within time limit [2017/19]
Fees paidRenewal fee
31.07.2014Renewal fee patent year 03
31.07.2015Renewal fee patent year 04
Opt-out from the exclusive  Tooltip
competence of the Unified
Patent Court		 See the Register of the Unified Patent Court for opt-out data
Responsibility for the accuracy, completeness or quality of the data displayed under the link provided lies entirely with the Unified Patent Court.
Lapses during opposition  TooltipHU25.07.2012
AL01.06.2016
AT01.06.2016
BE01.06.2016
BG01.06.2016
CY01.06.2016
CZ01.06.2016
DK01.06.2016
EE01.06.2016
ES01.06.2016
FI01.06.2016
HR01.06.2016
IT01.06.2016
LT01.06.2016
LV01.06.2016
MC01.06.2016
MK01.06.2016
NL01.06.2016
PL01.06.2016
RO01.06.2016
RS01.06.2016
SE01.06.2016
SI01.06.2016
SK01.06.2016
SM01.06.2016
TR01.06.2016
IE25.07.2016
LU25.07.2016
MT31.07.2016
NO01.09.2016
GR02.09.2016
IS01.10.2016
PT03.10.2016
[2018/46]
Former [2018/45]HU25.07.2012
AT01.06.2016
BE01.06.2016
BG01.06.2016
CY01.06.2016
CZ01.06.2016
DK01.06.2016
EE01.06.2016
ES01.06.2016
FI01.06.2016
HR01.06.2016
IT01.06.2016
LT01.06.2016
LV01.06.2016
MC01.06.2016
MK01.06.2016
NL01.06.2016
PL01.06.2016
RO01.06.2016
RS01.06.2016
SE01.06.2016
SI01.06.2016
SK01.06.2016
SM01.06.2016
TR01.06.2016
IE25.07.2016
LU25.07.2016
MT31.07.2016
NO01.09.2016
GR02.09.2016
IS01.10.2016
PT03.10.2016
Former [2018/38]HU25.07.2012
AT01.06.2016
BE01.06.2016
BG01.06.2016
CY01.06.2016
CZ01.06.2016
DK01.06.2016
EE01.06.2016
ES01.06.2016
FI01.06.2016
HR01.06.2016
IT01.06.2016
LT01.06.2016
LV01.06.2016
MC01.06.2016
MK01.06.2016
NL01.06.2016
PL01.06.2016
RO01.06.2016
RS01.06.2016
SE01.06.2016
SI01.06.2016
SK01.06.2016
SM01.06.2016
IE25.07.2016
LU25.07.2016
MT31.07.2016
NO01.09.2016
GR02.09.2016
IS01.10.2016
PT03.10.2016
Former [2018/31]HU25.07.2012
AT01.06.2016
BE01.06.2016
CY01.06.2016
CZ01.06.2016
DK01.06.2016
EE01.06.2016
ES01.06.2016
FI01.06.2016
HR01.06.2016
IT01.06.2016
LT01.06.2016
LV01.06.2016
MC01.06.2016
MK01.06.2016
NL01.06.2016
PL01.06.2016
RO01.06.2016
RS01.06.2016
SE01.06.2016
SI01.06.2016
SK01.06.2016
SM01.06.2016
IE25.07.2016
LU25.07.2016
MT31.07.2016
NO01.09.2016
GR02.09.2016
IS01.10.2016
PT03.10.2016
Former [2018/28]HU25.07.2012
AT01.06.2016
BE01.06.2016
CY01.06.2016
CZ01.06.2016
DK01.06.2016
EE01.06.2016
ES01.06.2016
FI01.06.2016
HR01.06.2016
IT01.06.2016
LT01.06.2016
LV01.06.2016
MC01.06.2016
MK01.06.2016
NL01.06.2016
PL01.06.2016
RO01.06.2016
RS01.06.2016
SE01.06.2016
SI01.06.2016
SK01.06.2016
SM01.06.2016
IE25.07.2016
LU25.07.2016
NO01.09.2016
GR02.09.2016
IS01.10.2016
PT03.10.2016
Former [2017/37]AT01.06.2016
BE01.06.2016
CZ01.06.2016
DK01.06.2016
EE01.06.2016
ES01.06.2016
FI01.06.2016
HR01.06.2016
IT01.06.2016
LT01.06.2016
LV01.06.2016
MC01.06.2016
NL01.06.2016
PL01.06.2016
RO01.06.2016
RS01.06.2016
SE01.06.2016
SI01.06.2016
SK01.06.2016
SM01.06.2016
IE25.07.2016
LU25.07.2016
NO01.09.2016
GR02.09.2016
IS01.10.2016
PT03.10.2016
Former [2017/17]AT01.06.2016
BE01.06.2016
CZ01.06.2016
EE01.06.2016
ES01.06.2016
FI01.06.2016
HR01.06.2016
IT01.06.2016
LT01.06.2016
LV01.06.2016
MC01.06.2016
NL01.06.2016
PL01.06.2016
RO01.06.2016
RS01.06.2016
SE01.06.2016
SK01.06.2016
SM01.06.2016
NO01.09.2016
GR02.09.2016
IS01.10.2016
PT03.10.2016
Former [2017/11]AT01.06.2016
BE01.06.2016
CZ01.06.2016
EE01.06.2016
ES01.06.2016
FI01.06.2016
HR01.06.2016
IT01.06.2016
LT01.06.2016
LV01.06.2016
NL01.06.2016
PL01.06.2016
RO01.06.2016
RS01.06.2016
SE01.06.2016
SK01.06.2016
SM01.06.2016
NO01.09.2016
GR02.09.2016
IS01.10.2016
PT03.10.2016
Former [2017/10]BE01.06.2016
CZ01.06.2016
EE01.06.2016
ES01.06.2016
FI01.06.2016
HR01.06.2016
IT01.06.2016
LT01.06.2016
LV01.06.2016
NL01.06.2016
PL01.06.2016
RO01.06.2016
RS01.06.2016
SE01.06.2016
SK01.06.2016
NO01.09.2016
GR02.09.2016
IS01.10.2016
Former [2017/09]CZ01.06.2016
EE01.06.2016
ES01.06.2016
FI01.06.2016
HR01.06.2016
IT01.06.2016
LT01.06.2016
LV01.06.2016
NL01.06.2016
RO01.06.2016
RS01.06.2016
SE01.06.2016
BE31.07.2016
NO01.09.2016
GR02.09.2016
Former [2017/03]ES01.06.2016
FI01.06.2016
HR01.06.2016
LT01.06.2016
LV01.06.2016
NL01.06.2016
RS01.06.2016
SE01.06.2016
BE31.07.2016
NO01.09.2016
GR02.09.2016
Former [2016/52]ES01.06.2016
FI01.06.2016
HR01.06.2016
LT01.06.2016
LV01.06.2016
NL01.06.2016
RS01.06.2016
SE01.06.2016
NO01.09.2016
GR02.09.2016
Former [2016/51]ES01.06.2016
FI01.06.2016
HR01.06.2016
LT01.06.2016
LV01.06.2016
RS01.06.2016
NO01.09.2016
GR02.09.2016
Former [2016/50]ES01.06.2016
FI01.06.2016
HR01.06.2016
LT01.06.2016
LV01.06.2016
RS01.06.2016
NO01.09.2016
Former [2016/49]FI01.06.2016
LT01.06.2016
NO01.09.2016
Former [2016/46]LT01.06.2016
NO01.09.2016
Cited inInternational search[IDA]CH680588  (LONZA AG) [ID] 1-14 * page 2, line 14 - line 21 * * page 2, line 23 - line 46 * * page 4; claim 3 * [A] 15;
 KR20090022032  [ ] (KOREA RES INST CHEM TECH [KR]);
 [A]WO2009062731  (LONZA AG [CH], et al) [A] 1-15 * page 2, line 4 - line 14 * * page 3 - page 5; examples 1-5 *;
 [XA]  - LEE, H. ET AL., "Method for preparing optically active alkyl 3-hydroxybutanoate derivative", CAPLUS, CHEMICAL ABSTRACTS SERVICE, (2009), Database accession no. 2009:278677, XP002666098 [X] 15 * the whole document * [A] 1-14
 [A]  - SONG, C.E. ET AL., "New Method for the Preparation of (R)-Carnitine", TETRAHEDRON ASYMMETRY, (199505), vol. 6, no. 5, pages 1063 - 1066, XP004048201 [A] 1-15 * abstract * * page 1063, line 10 - page 1064, line 26 * * scheme: 1 *

DOI:   http://dx.doi.org/10.1016/0957-4166(95)00125-9
 [A]  - "Burkholderia cepacia triacylglycerol lipase sequence, SEQ ID 177", Geneseq, (20090108), Database accession no. AUR75024, XP002682343 [A] 1-15 * the whole document *
 [A]  - "Candida antarctica lipase B protein SEQ ID:1", Geneseq, (20100114), Database accession no. AXW34320, XP002682344 [A] 1-15 * the whole document *
by applicantUS5473104
 CH680588
 US2006046286
 US2007213524
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    - JOERGENSEN ET AL., J. BACTERIOL., (1991), vol. 173, pages 559 - 567
    - DALAL ET AL., J. BIOTECHNOL. APPL. BIOCHEM., (2008), vol. 51, pages 23 - 31
    - YANG ET AL., J. MOL. CATAL., B ENZYM., (2007), vol. 45, pages 91 - 96
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    - TETRAHEDRON LETTERS, (2007), vol. 48, no. 10, pages 1749 - 1752
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