EP2753324 - LIPOPHILIC DOPAMINE DERIVATIVES AND THEIR USE [Right-click to bookmark this link] | Status | No opposition filed within time limit Status updated on 26.10.2018 Database last updated on 31.08.2024 | |
Former | The patent has been granted Status updated on 17.11.2017 | ||
Former | Grant of patent is intended Status updated on 09.07.2017 | ||
Former | Examination is in progress Status updated on 14.12.2016 | Most recent event Tooltip | 17.07.2020 | Lapse of the patent in a contracting state New state(s): AL | published on 19.08.2020 [2020/34] | Applicant(s) | For all designated states Novaliq GmbH Im Neuenheimer Feld 515 69120 Heidelberg / DE | [2014/29] | Inventor(s) | 01 /
GÜNTHER, Bernhard Schriesheimerstrasse 19 69221 Dossenheim / DE | 02 /
THEISINGER, Bastian Zur Waldau 23 68239 Mannheim / DE | 03 /
THEISINGER, Sonja Zur Waldau 23 68239 Mannheim / DE | [2014/29] | Representative(s) | Cremer, Karsten Pharma Patents International AG Leonhardsgraben 52 4051 Basel / CH | [N/P] |
Former [2014/29] | Cremer, Karsten Pharma Concepts GmbH Almstadtstr. 7 10119 Berlin / DE | Application number, filing date | 12750390.2 | 24.08.2012 | [2017/51] | WO2012EP66504 | Priority number, date | EP20110180167 | 06.09.2011 Original published format: EP 11180167 | [2014/29] | Filing language | EN | Procedural language | EN | Publication | Type: | A1 Application with search report | No.: | WO2013034457 | Date: | 14.03.2013 | Language: | EN | [2013/11] | Type: | A1 Application with search report | No.: | EP2753324 | Date: | 16.07.2014 | Language: | EN | The application published by WIPO in one of the EPO official languages on 14.03.2013 takes the place of the publication of the European patent application. | [2014/29] | Type: | B1 Patent specification | No.: | EP2753324 | Date: | 20.12.2017 | Language: | EN | [2017/51] | Search report(s) | International search report - published on: | EP | 14.03.2013 | Classification | IPC: | A61K31/222, C07C233/22, A61P9/10, A01N1/02, C07C233/33 | [2014/29] | CPC: |
C07C233/18 (EP,US);
C07C235/84 (US);
A01N1/0226 (EP,US);
A61P13/02 (EP);
A61P13/12 (EP);
A61P25/00 (EP);
A61P37/06 (EP);
A61P9/10 (EP);
A61P9/14 (EP);
C07C231/12 (US)
(-)
| Designated contracting states | AL, AT, BE, BG, CH, CY, CZ, DE, DK, EE, ES, FI, FR, GB, GR, HR, HU, IE, IS, IT, LI, LT, LU, LV, MC, MK, MT, NL, NO, PL, PT, RO, RS, SE, SI, SK, SM, TR [2014/29] | Extension states | BA | Not yet paid | ME | Not yet paid | Title | German: | LIPOPHILE DOPAMINDERIVATE UND IHRE VERWENDUNG | [2014/29] | English: | LIPOPHILIC DOPAMINE DERIVATIVES AND THEIR USE | [2014/29] | French: | DÉRIVÉS DE LA DOPAMINE LIPOPHILE ET LEUR UTILISATION | [2017/27] |
Former [2014/29] | DÉRIVÉS DE DOPAMINE LIPOPHILES ET LEUR UTILISATION | Entry into regional phase | 07.04.2014 | National basic fee paid | 07.04.2014 | Designation fee(s) paid | 07.04.2014 | Examination fee paid | Examination procedure | 07.04.2014 | Examination requested [2014/29] | 17.10.2014 | Amendment by applicant (claims and/or description) | 09.03.2016 | Despatch of a communication from the examining division (Time limit: M04) | 18.07.2016 | Reply to a communication from the examining division | 05.12.2016 | Despatch of a communication from the examining division (Time limit: M02) | 25.01.2017 | Reply to a communication from the examining division | 10.07.2017 | Communication of intention to grant the patent | 10.11.2017 | Fee for grant paid | 10.11.2017 | Fee for publishing/printing paid | 10.11.2017 | Receipt of the translation of the claim(s) | Divisional application(s) | The date of the Examining Division's first communication in respect of the earliest application for which a communication has been issued is 09.03.2016 | Opposition(s) | 21.09.2018 | No opposition filed within time limit [2018/48] | Fees paid | Renewal fee | 01.09.2014 | Renewal fee patent year 03 | 31.08.2015 | Renewal fee patent year 04 | 31.08.2016 | Renewal fee patent year 05 | 31.08.2017 | Renewal fee patent year 06 |
Opt-out from the exclusive Tooltip competence of the Unified Patent Court | See the Register of the Unified Patent Court for opt-out data | ||
Responsibility for the accuracy, completeness or quality of the data displayed under the link provided lies entirely with the Unified Patent Court. | Lapses during opposition Tooltip | HU | 24.08.2012 | AL | 20.12.2017 | AT | 20.12.2017 | CY | 20.12.2017 | CZ | 20.12.2017 | DK | 20.12.2017 | EE | 20.12.2017 | ES | 20.12.2017 | FI | 20.12.2017 | HR | 20.12.2017 | IT | 20.12.2017 | LT | 20.12.2017 | LV | 20.12.2017 | MC | 20.12.2017 | MK | 20.12.2017 | NL | 20.12.2017 | PL | 20.12.2017 | PT | 20.12.2017 | RO | 20.12.2017 | RS | 20.12.2017 | SE | 20.12.2017 | SI | 20.12.2017 | SK | 20.12.2017 | SM | 20.12.2017 | TR | 20.12.2017 | BG | 20.03.2018 | NO | 20.03.2018 | GR | 21.03.2018 | IS | 20.04.2018 | IE | 24.08.2018 | LU | 24.08.2018 | MT | 24.08.2018 | BE | 31.08.2018 | CH | 31.08.2018 | LI | 31.08.2018 | [2020/34] |
Former [2020/31] | HU | 24.08.2012 | |
AT | 20.12.2017 | ||
CY | 20.12.2017 | ||
CZ | 20.12.2017 | ||
DK | 20.12.2017 | ||
EE | 20.12.2017 | ||
ES | 20.12.2017 | ||
FI | 20.12.2017 | ||
HR | 20.12.2017 | ||
IT | 20.12.2017 | ||
LT | 20.12.2017 | ||
LV | 20.12.2017 | ||
MC | 20.12.2017 | ||
MK | 20.12.2017 | ||
NL | 20.12.2017 | ||
PL | 20.12.2017 | ||
PT | 20.12.2017 | ||
RO | 20.12.2017 | ||
RS | 20.12.2017 | ||
SE | 20.12.2017 | ||
SI | 20.12.2017 | ||
SK | 20.12.2017 | ||
SM | 20.12.2017 | ||
TR | 20.12.2017 | ||
BG | 20.03.2018 | ||
NO | 20.03.2018 | ||
GR | 21.03.2018 | ||
IS | 20.04.2018 | ||
IE | 24.08.2018 | ||
LU | 24.08.2018 | ||
MT | 24.08.2018 | ||
BE | 31.08.2018 | ||
CH | 31.08.2018 | ||
LI | 31.08.2018 | ||
Former [2020/30] | HU | 24.08.2012 | |
AT | 20.12.2017 | ||
CY | 20.12.2017 | ||
CZ | 20.12.2017 | ||
DK | 20.12.2017 | ||
EE | 20.12.2017 | ||
ES | 20.12.2017 | ||
FI | 20.12.2017 | ||
HR | 20.12.2017 | ||
IT | 20.12.2017 | ||
LT | 20.12.2017 | ||
LV | 20.12.2017 | ||
MC | 20.12.2017 | ||
NL | 20.12.2017 | ||
PL | 20.12.2017 | ||
PT | 20.12.2017 | ||
RO | 20.12.2017 | ||
RS | 20.12.2017 | ||
SE | 20.12.2017 | ||
SI | 20.12.2017 | ||
SK | 20.12.2017 | ||
SM | 20.12.2017 | ||
TR | 20.12.2017 | ||
BG | 20.03.2018 | ||
NO | 20.03.2018 | ||
GR | 21.03.2018 | ||
IS | 20.04.2018 | ||
IE | 24.08.2018 | ||
LU | 24.08.2018 | ||
MT | 24.08.2018 | ||
BE | 31.08.2018 | ||
CH | 31.08.2018 | ||
LI | 31.08.2018 | ||
Former [2020/28] | HU | 24.08.2012 | |
AT | 20.12.2017 | ||
CY | 20.12.2017 | ||
CZ | 20.12.2017 | ||
DK | 20.12.2017 | ||
EE | 20.12.2017 | ||
ES | 20.12.2017 | ||
FI | 20.12.2017 | ||
HR | 20.12.2017 | ||
IT | 20.12.2017 | ||
LT | 20.12.2017 | ||
LV | 20.12.2017 | ||
MC | 20.12.2017 | ||
NL | 20.12.2017 | ||
PL | 20.12.2017 | ||
PT | 20.12.2017 | ||
RO | 20.12.2017 | ||
RS | 20.12.2017 | ||
SE | 20.12.2017 | ||
SI | 20.12.2017 | ||
SK | 20.12.2017 | ||
SM | 20.12.2017 | ||
TR | 20.12.2017 | ||
BG | 20.03.2018 | ||
NO | 20.03.2018 | ||
GR | 21.03.2018 | ||
IS | 20.04.2018 | ||
LU | 24.08.2018 | ||
MT | 24.08.2018 | ||
BE | 31.08.2018 | ||
CH | 31.08.2018 | ||
LI | 31.08.2018 | ||
Former [2020/16] | AT | 20.12.2017 | |
CY | 20.12.2017 | ||
CZ | 20.12.2017 | ||
DK | 20.12.2017 | ||
EE | 20.12.2017 | ||
ES | 20.12.2017 | ||
FI | 20.12.2017 | ||
HR | 20.12.2017 | ||
IT | 20.12.2017 | ||
LT | 20.12.2017 | ||
LV | 20.12.2017 | ||
MC | 20.12.2017 | ||
NL | 20.12.2017 | ||
PL | 20.12.2017 | ||
RO | 20.12.2017 | ||
RS | 20.12.2017 | ||
SE | 20.12.2017 | ||
SI | 20.12.2017 | ||
SK | 20.12.2017 | ||
SM | 20.12.2017 | ||
TR | 20.12.2017 | ||
BG | 20.03.2018 | ||
NO | 20.03.2018 | ||
GR | 21.03.2018 | ||
IS | 20.04.2018 | ||
LU | 24.08.2018 | ||
MT | 24.08.2018 | ||
BE | 31.08.2018 | ||
CH | 31.08.2018 | ||
LI | 31.08.2018 | ||
Former [2020/08] | AT | 20.12.2017 | |
CY | 20.12.2017 | ||
CZ | 20.12.2017 | ||
DK | 20.12.2017 | ||
EE | 20.12.2017 | ||
ES | 20.12.2017 | ||
FI | 20.12.2017 | ||
HR | 20.12.2017 | ||
IT | 20.12.2017 | ||
LT | 20.12.2017 | ||
LV | 20.12.2017 | ||
MC | 20.12.2017 | ||
NL | 20.12.2017 | ||
PL | 20.12.2017 | ||
RO | 20.12.2017 | ||
RS | 20.12.2017 | ||
SE | 20.12.2017 | ||
SI | 20.12.2017 | ||
SK | 20.12.2017 | ||
SM | 20.12.2017 | ||
BG | 20.03.2018 | ||
NO | 20.03.2018 | ||
GR | 21.03.2018 | ||
IS | 20.04.2018 | ||
LU | 24.08.2018 | ||
MT | 24.08.2018 | ||
BE | 31.08.2018 | ||
CH | 31.08.2018 | ||
LI | 31.08.2018 | ||
Former [2019/38] | AT | 20.12.2017 | |
CY | 20.12.2017 | ||
CZ | 20.12.2017 | ||
DK | 20.12.2017 | ||
EE | 20.12.2017 | ||
ES | 20.12.2017 | ||
FI | 20.12.2017 | ||
HR | 20.12.2017 | ||
IT | 20.12.2017 | ||
LT | 20.12.2017 | ||
LV | 20.12.2017 | ||
MC | 20.12.2017 | ||
NL | 20.12.2017 | ||
PL | 20.12.2017 | ||
RO | 20.12.2017 | ||
RS | 20.12.2017 | ||
SE | 20.12.2017 | ||
SI | 20.12.2017 | ||
SK | 20.12.2017 | ||
SM | 20.12.2017 | ||
BG | 20.03.2018 | ||
NO | 20.03.2018 | ||
GR | 21.03.2018 | ||
IS | 20.04.2018 | ||
LU | 24.08.2018 | ||
BE | 31.08.2018 | ||
CH | 31.08.2018 | ||
LI | 31.08.2018 | ||
Former [2019/21] | AT | 20.12.2017 | |
CY | 20.12.2017 | ||
CZ | 20.12.2017 | ||
DK | 20.12.2017 | ||
EE | 20.12.2017 | ||
ES | 20.12.2017 | ||
FI | 20.12.2017 | ||
HR | 20.12.2017 | ||
IT | 20.12.2017 | ||
LT | 20.12.2017 | ||
LV | 20.12.2017 | ||
MC | 20.12.2017 | ||
NL | 20.12.2017 | ||
PL | 20.12.2017 | ||
RO | 20.12.2017 | ||
RS | 20.12.2017 | ||
SE | 20.12.2017 | ||
SI | 20.12.2017 | ||
SK | 20.12.2017 | ||
SM | 20.12.2017 | ||
BG | 20.03.2018 | ||
NO | 20.03.2018 | ||
GR | 21.03.2018 | ||
IS | 20.04.2018 | ||
LU | 24.08.2018 | ||
CH | 31.08.2018 | ||
LI | 31.08.2018 | ||
Former [2019/15] | AT | 20.12.2017 | |
CY | 20.12.2017 | ||
CZ | 20.12.2017 | ||
DK | 20.12.2017 | ||
EE | 20.12.2017 | ||
ES | 20.12.2017 | ||
FI | 20.12.2017 | ||
HR | 20.12.2017 | ||
IT | 20.12.2017 | ||
LT | 20.12.2017 | ||
LV | 20.12.2017 | ||
MC | 20.12.2017 | ||
NL | 20.12.2017 | ||
PL | 20.12.2017 | ||
RO | 20.12.2017 | ||
RS | 20.12.2017 | ||
SE | 20.12.2017 | ||
SI | 20.12.2017 | ||
SK | 20.12.2017 | ||
SM | 20.12.2017 | ||
BG | 20.03.2018 | ||
NO | 20.03.2018 | ||
GR | 21.03.2018 | ||
IS | 20.04.2018 | ||
Former [2019/13] | AT | 20.12.2017 | |
CY | 20.12.2017 | ||
CZ | 20.12.2017 | ||
DK | 20.12.2017 | ||
EE | 20.12.2017 | ||
ES | 20.12.2017 | ||
FI | 20.12.2017 | ||
HR | 20.12.2017 | ||
IT | 20.12.2017 | ||
LT | 20.12.2017 | ||
LV | 20.12.2017 | ||
NL | 20.12.2017 | ||
PL | 20.12.2017 | ||
RO | 20.12.2017 | ||
RS | 20.12.2017 | ||
SE | 20.12.2017 | ||
SI | 20.12.2017 | ||
SK | 20.12.2017 | ||
SM | 20.12.2017 | ||
BG | 20.03.2018 | ||
NO | 20.03.2018 | ||
GR | 21.03.2018 | ||
IS | 20.04.2018 | ||
Former [2018/51] | AT | 20.12.2017 | |
CY | 20.12.2017 | ||
CZ | 20.12.2017 | ||
DK | 20.12.2017 | ||
EE | 20.12.2017 | ||
ES | 20.12.2017 | ||
FI | 20.12.2017 | ||
HR | 20.12.2017 | ||
IT | 20.12.2017 | ||
LT | 20.12.2017 | ||
LV | 20.12.2017 | ||
NL | 20.12.2017 | ||
PL | 20.12.2017 | ||
RO | 20.12.2017 | ||
RS | 20.12.2017 | ||
SE | 20.12.2017 | ||
SK | 20.12.2017 | ||
SM | 20.12.2017 | ||
BG | 20.03.2018 | ||
NO | 20.03.2018 | ||
GR | 21.03.2018 | ||
IS | 20.04.2018 | ||
Former [2018/40] | AT | 20.12.2017 | |
CY | 20.12.2017 | ||
CZ | 20.12.2017 | ||
EE | 20.12.2017 | ||
ES | 20.12.2017 | ||
FI | 20.12.2017 | ||
HR | 20.12.2017 | ||
IT | 20.12.2017 | ||
LT | 20.12.2017 | ||
LV | 20.12.2017 | ||
NL | 20.12.2017 | ||
PL | 20.12.2017 | ||
RO | 20.12.2017 | ||
RS | 20.12.2017 | ||
SE | 20.12.2017 | ||
SK | 20.12.2017 | ||
SM | 20.12.2017 | ||
BG | 20.03.2018 | ||
NO | 20.03.2018 | ||
GR | 21.03.2018 | ||
IS | 20.04.2018 | ||
Former [2018/39] | AT | 20.12.2017 | |
CY | 20.12.2017 | ||
CZ | 20.12.2017 | ||
EE | 20.12.2017 | ||
ES | 20.12.2017 | ||
FI | 20.12.2017 | ||
HR | 20.12.2017 | ||
IT | 20.12.2017 | ||
LT | 20.12.2017 | ||
LV | 20.12.2017 | ||
NL | 20.12.2017 | ||
PL | 20.12.2017 | ||
RS | 20.12.2017 | ||
SE | 20.12.2017 | ||
SK | 20.12.2017 | ||
SM | 20.12.2017 | ||
BG | 20.03.2018 | ||
NO | 20.03.2018 | ||
GR | 21.03.2018 | ||
IS | 20.04.2018 | ||
Former [2018/38] | AT | 20.12.2017 | |
CY | 20.12.2017 | ||
CZ | 20.12.2017 | ||
EE | 20.12.2017 | ||
ES | 20.12.2017 | ||
FI | 20.12.2017 | ||
HR | 20.12.2017 | ||
LT | 20.12.2017 | ||
LV | 20.12.2017 | ||
NL | 20.12.2017 | ||
PL | 20.12.2017 | ||
RS | 20.12.2017 | ||
SE | 20.12.2017 | ||
SK | 20.12.2017 | ||
SM | 20.12.2017 | ||
BG | 20.03.2018 | ||
NO | 20.03.2018 | ||
GR | 21.03.2018 | ||
IS | 20.04.2018 | ||
Former [2018/37] | CY | 20.12.2017 | |
CZ | 20.12.2017 | ||
EE | 20.12.2017 | ||
ES | 20.12.2017 | ||
FI | 20.12.2017 | ||
HR | 20.12.2017 | ||
LT | 20.12.2017 | ||
LV | 20.12.2017 | ||
NL | 20.12.2017 | ||
PL | 20.12.2017 | ||
RS | 20.12.2017 | ||
SE | 20.12.2017 | ||
SK | 20.12.2017 | ||
SM | 20.12.2017 | ||
BG | 20.03.2018 | ||
NO | 20.03.2018 | ||
GR | 21.03.2018 | ||
Former [2018/34] | FI | 20.12.2017 | |
HR | 20.12.2017 | ||
LT | 20.12.2017 | ||
LV | 20.12.2017 | ||
NL | 20.12.2017 | ||
RS | 20.12.2017 | ||
SE | 20.12.2017 | ||
BG | 20.03.2018 | ||
NO | 20.03.2018 | ||
GR | 21.03.2018 | ||
Former [2018/24] | FI | 20.12.2017 | |
HR | 20.12.2017 | ||
LT | 20.12.2017 | ||
LV | 20.12.2017 | ||
RS | 20.12.2017 | ||
SE | 20.12.2017 | ||
BG | 20.03.2018 | ||
NO | 20.03.2018 | ||
GR | 21.03.2018 | ||
Former [2018/23] | FI | 20.12.2017 | |
HR | 20.12.2017 | ||
LT | 20.12.2017 | ||
RS | 20.12.2017 | ||
SE | 20.12.2017 | ||
NO | 20.03.2018 | ||
GR | 21.03.2018 | ||
Former [2018/22] | FI | 20.12.2017 | |
LT | 20.12.2017 | ||
NO | 20.03.2018 | Cited in | International search | [X]EP0333522 (MITSUI TOATSU CHEMICALS [JP]) [X] 1-4,13-15 * claim - ** examples 83,85,89 *; | [I]WO2009015752 (LOESEL RALF [DE], et al) [I] 1-15 * page 9; example - * | Examination | WO2010129954 | - TSAGOGIORGAS C ET AL, "N-Octanoyl-Dopamine Reduces Inflammation and Compared To Dopamine Improves Renal Function in Acute Renal Failure", TRANSPLANTATION, WILLIAMS AND WILKINS, GB, (20100816), vol. 90, no. 2 supplement, doi:10.1097/00007890-201007272-00073, ISSN 0041-1337, page 37, XP002608348 DOI: http://dx.doi.org/10.1097/00007890-201007272-00073 | by applicant | WO2009015752 | - LOSEL RM ET AL., "N-octanoyl dopamine, a non-haemodynamic dopamine derivative, for cell protection during hypothermic organ preservation", PLOS ONE., (20100316), vol. 5, no. 3, doi:doi:10.1371/journal.pone.0009713, page E9713, XP002608347 DOI: http://dx.doi.org/10.1371/journal.pone.0009713 | - SCHNUELLE P ET AL., "Effects of donor pre-treatment with dopamine on graft function after kidney transplantation: a randomized controlled trial", JAMA, (20090909), vol. 302, no. 10, pages 1067 - 75 | - SCHNETZE U ET AL., J. CRYOBIOL., (2006), vol. 53, no. 3, page 375 | - TSAGOGIORGAS C ET AL., TRANSPLANTATION, (2010), vol. 90, page 37 | - TSAGOGIORGAS, C. ET AL., TRANSPLANTATION, (2010), vol. 90, page 37 | - GREFFRATH, W. ET AL., ACTA PHYSIOLOGICA, (2011), vol. 201, no. 682, page 108 | - H. STRICKER, Physikalische Pharmazie, 3rd Edition,, page 440 | - S. VEMURI ET AL., "Preparation and characterization of liposomes as therapeutic delivery systems: a review", PHARM ACTA HELV., (1995), vol. 70, no. 2, doi:doi:10.1016/0031-6865(95)00010-7, pages 95 - 111, XP002357174 DOI: http://dx.doi.org/10.1016/0031-6865(95)00010-7 | WO2011EP64074 |