EP2686324 - PIPERIDINE CARBOXAMIDE SPIROHYDANTOIN CGRP RECEPTOR ANTAGONISTS [Right-click to bookmark this link] | Status | No opposition filed within time limit Status updated on 11.11.2016 Database last updated on 31.08.2024 | Most recent event Tooltip | 12.10.2018 | Lapse of the patent in a contracting state New state(s): AL | published on 14.11.2018 [2018/46] | Applicant(s) | For all designated states Merck Sharp & Dohme Corp. 126 East Lincoln Avenue Rahway, NJ 07065-0907 / US | [2014/04] | Inventor(s) | 01 /
BELL, Ian, M. 770 Sumneytown Pike West Point, PA 19486 / US | 02 /
FRALEY, Mark, E. 770 Sumneytown Pike West Point, PA 19486 / US | 03 /
GALLICHO, Steven, N. 770 Sumneytown Pike West Point, PA 19486 / US | 04 /
MITCHELL, Helen, J. 770 Sumneytown Pike West Point, PA 19486 / US | 05 /
WANG, Chang 770 Sumneytown Pike West Point, PA 19486 / US | [2016/01] |
Former [2014/04] | 01 /
BELL, Ian, M. 770 Sumneytown Pike West Point, PA 19486 / US | ||
02 /
FRALEY, Mark, E. 770 Sumneytown Pike West Point, PA 19486 / US | |||
03 /
GALLICHO, Steven, N. 770 Sumneytown Pike West Point, PA 19486 / US | |||
04 /
MITCHELL, Helen, J. 770 Sumneytown Pike West Point, PA 19486 / US | |||
05 /
WANG, Chang 770 Sumneytown Pike West Point, PA 19486 / US | Representative(s) | Buchan, Gavin MacNicol Merck & Co., Inc. European Patent Department Hertford Road Hoddesdon, Hertfordshire EN11 9BU / GB | [2016/01] |
Former [2014/04] | Buchan, Gavin MacNicol Merck & Co., Inc. European Patent Department Hertford Road Hoddesdon, Hertfordshire EN11 9BU / GB | Application number, filing date | 12760168.0 | 14.03.2012 | [2016/01] | WO2012US28976 | Priority number, date | US201161453989P | 18.03.2011 Original published format: US 201161453989 P | [2014/04] | Filing language | EN | Procedural language | EN | Publication | Type: | A1 Application with search report | No.: | WO2012129014 | Date: | 27.09.2012 | Language: | EN | [2012/39] | Type: | A1 Application with search report | No.: | EP2686324 | Date: | 22.01.2014 | Language: | EN | The application published by WIPO in one of the EPO official languages on 27.09.2012 takes the place of the publication of the European patent application. | [2014/04] | Type: | B1 Patent specification | No.: | EP2686324 | Date: | 06.01.2016 | Language: | EN | [2016/01] | Search report(s) | International search report - published on: | US | 27.09.2012 | (Supplementary) European search report - dispatched on: | EP | 22.10.2014 | Classification | IPC: | C07D487/10, A61K31/445, A61P25/06, C07D401/12 | [2015/32] | CPC: |
C07D401/12 (EP,US);
A61K31/445 (EP,US);
A61P25/06 (EP);
A61P29/00 (EP);
A61P43/00 (EP)
|
Former IPC [2014/47] | C07D487/10, A61K31/445, A61P25/06 | ||
Former IPC [2014/04] | C07D487/10, A61K31/445 | Designated contracting states | AL, AT, BE, BG, CH, CY, CZ, DE, DK, EE, ES, FI, FR, GB, GR, HR, HU, IE, IS, IT, LI, LT, LU, LV, MC, MK, MT, NL, NO, PL, PT, RO, RS, SE, SI, SK, SM, TR [2014/04] | Extension states | BA | Not yet paid | ME | Not yet paid | Title | German: | PIPERIDINCARBOXAMID-SPIROHYDANTOIN-CGRP-REZEPTORANTAGONISTEN | [2014/04] | English: | PIPERIDINE CARBOXAMIDE SPIROHYDANTOIN CGRP RECEPTOR ANTAGONISTS | [2014/04] | French: | ANTAGONISTES SPIROHYDANTOÏNES DES RÉCEPTEURS CGRP DE TYPE CARBOXAMIDE DE PIPÉRIDINE | [2014/04] | Entry into regional phase | 18.10.2013 | National basic fee paid | 18.10.2013 | Search fee paid | 18.10.2013 | Designation fee(s) paid | 18.10.2013 | Examination fee paid | Examination procedure | 26.09.2013 | Amendment by applicant (claims and/or description) | 18.10.2013 | Examination requested [2014/04] | 09.07.2015 | Communication of intention to grant the patent | 29.10.2015 | Fee for grant paid | 29.10.2015 | Fee for publishing/printing paid | 29.10.2015 | Receipt of the translation of the claim(s) | Divisional application(s) | The date of the Examining Division's first communication in respect of the earliest application for which a communication has been issued is 09.07.2015 | Opposition(s) | 07.10.2016 | No opposition filed within time limit [2016/50] | Fees paid | Renewal fee | 10.03.2014 | Renewal fee patent year 03 | 06.03.2015 | Renewal fee patent year 04 |
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Responsibility for the accuracy, completeness or quality of the data displayed under the link provided lies entirely with the Unified Patent Court. | Lapses during opposition Tooltip | HU | 14.03.2012 | AL | 06.01.2016 | AT | 06.01.2016 | BE | 06.01.2016 | CY | 06.01.2016 | CZ | 06.01.2016 | DK | 06.01.2016 | EE | 06.01.2016 | ES | 06.01.2016 | FI | 06.01.2016 | HR | 06.01.2016 | IT | 06.01.2016 | LT | 06.01.2016 | LV | 06.01.2016 | MC | 06.01.2016 | MK | 06.01.2016 | NL | 06.01.2016 | PL | 06.01.2016 | RO | 06.01.2016 | RS | 06.01.2016 | SE | 06.01.2016 | SI | 06.01.2016 | SK | 06.01.2016 | SM | 06.01.2016 | TR | 06.01.2016 | IE | 14.03.2016 | LU | 14.03.2016 | CH | 31.03.2016 | LI | 31.03.2016 | MT | 31.03.2016 | BG | 06.04.2016 | NO | 06.04.2016 | GR | 07.04.2016 | IS | 06.05.2016 | PT | 06.05.2016 | [2018/46] |
Former [2018/31] | HU | 14.03.2012 | |
AT | 06.01.2016 | ||
BE | 06.01.2016 | ||
CY | 06.01.2016 | ||
CZ | 06.01.2016 | ||
DK | 06.01.2016 | ||
EE | 06.01.2016 | ||
ES | 06.01.2016 | ||
FI | 06.01.2016 | ||
HR | 06.01.2016 | ||
IT | 06.01.2016 | ||
LT | 06.01.2016 | ||
LV | 06.01.2016 | ||
MC | 06.01.2016 | ||
MK | 06.01.2016 | ||
NL | 06.01.2016 | ||
PL | 06.01.2016 | ||
RO | 06.01.2016 | ||
RS | 06.01.2016 | ||
SE | 06.01.2016 | ||
SI | 06.01.2016 | ||
SK | 06.01.2016 | ||
SM | 06.01.2016 | ||
TR | 06.01.2016 | ||
IE | 14.03.2016 | ||
LU | 14.03.2016 | ||
CH | 31.03.2016 | ||
LI | 31.03.2016 | ||
MT | 31.03.2016 | ||
BG | 06.04.2016 | ||
NO | 06.04.2016 | ||
GR | 07.04.2016 | ||
IS | 06.05.2016 | ||
PT | 06.05.2016 | ||
Former [2018/29] | HU | 14.03.2012 | |
AT | 06.01.2016 | ||
BE | 06.01.2016 | ||
CY | 06.01.2016 | ||
CZ | 06.01.2016 | ||
DK | 06.01.2016 | ||
EE | 06.01.2016 | ||
ES | 06.01.2016 | ||
FI | 06.01.2016 | ||
HR | 06.01.2016 | ||
IT | 06.01.2016 | ||
LT | 06.01.2016 | ||
LV | 06.01.2016 | ||
MC | 06.01.2016 | ||
MK | 06.01.2016 | ||
MT | 06.01.2016 | ||
NL | 06.01.2016 | ||
PL | 06.01.2016 | ||
RO | 06.01.2016 | ||
RS | 06.01.2016 | ||
SE | 06.01.2016 | ||
SI | 06.01.2016 | ||
SK | 06.01.2016 | ||
SM | 06.01.2016 | ||
TR | 06.01.2016 | ||
IE | 14.03.2016 | ||
LU | 14.03.2016 | ||
CH | 31.03.2016 | ||
LI | 31.03.2016 | ||
BG | 06.04.2016 | ||
NO | 06.04.2016 | ||
GR | 07.04.2016 | ||
IS | 06.05.2016 | ||
PT | 06.05.2016 | ||
Former [2018/28] | HU | 14.03.2012 | |
AT | 06.01.2016 | ||
BE | 06.01.2016 | ||
CY | 06.01.2016 | ||
CZ | 06.01.2016 | ||
DK | 06.01.2016 | ||
EE | 06.01.2016 | ||
ES | 06.01.2016 | ||
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HR | 06.01.2016 | ||
IT | 06.01.2016 | ||
LT | 06.01.2016 | ||
LV | 06.01.2016 | ||
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MK | 06.01.2016 | ||
MT | 06.01.2016 | ||
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PL | 06.01.2016 | ||
RO | 06.01.2016 | ||
RS | 06.01.2016 | ||
SE | 06.01.2016 | ||
SI | 06.01.2016 | ||
SK | 06.01.2016 | ||
SM | 06.01.2016 | ||
IE | 14.03.2016 | ||
LU | 14.03.2016 | ||
CH | 31.03.2016 | ||
LI | 31.03.2016 | ||
BG | 06.04.2016 | ||
NO | 06.04.2016 | ||
GR | 07.04.2016 | ||
IS | 06.05.2016 | ||
PT | 06.05.2016 | ||
Former [2017/47] | AT | 06.01.2016 | |
BE | 06.01.2016 | ||
CZ | 06.01.2016 | ||
DK | 06.01.2016 | ||
EE | 06.01.2016 | ||
ES | 06.01.2016 | ||
FI | 06.01.2016 | ||
HR | 06.01.2016 | ||
IT | 06.01.2016 | ||
LT | 06.01.2016 | ||
LV | 06.01.2016 | ||
MC | 06.01.2016 | ||
MT | 06.01.2016 | ||
NL | 06.01.2016 | ||
PL | 06.01.2016 | ||
RO | 06.01.2016 | ||
RS | 06.01.2016 | ||
SE | 06.01.2016 | ||
SI | 06.01.2016 | ||
SK | 06.01.2016 | ||
SM | 06.01.2016 | ||
IE | 14.03.2016 | ||
LU | 14.03.2016 | ||
CH | 31.03.2016 | ||
LI | 31.03.2016 | ||
BG | 06.04.2016 | ||
NO | 06.04.2016 | ||
GR | 07.04.2016 | ||
IS | 06.05.2016 | ||
PT | 06.05.2016 | ||
Former [2017/16] | AT | 06.01.2016 | |
BE | 06.01.2016 | ||
CZ | 06.01.2016 | ||
DK | 06.01.2016 | ||
EE | 06.01.2016 | ||
ES | 06.01.2016 | ||
FI | 06.01.2016 | ||
HR | 06.01.2016 | ||
IT | 06.01.2016 | ||
LT | 06.01.2016 | ||
LV | 06.01.2016 | ||
MC | 06.01.2016 | ||
NL | 06.01.2016 | ||
PL | 06.01.2016 | ||
RO | 06.01.2016 | ||
RS | 06.01.2016 | ||
SE | 06.01.2016 | ||
SI | 06.01.2016 | ||
SK | 06.01.2016 | ||
SM | 06.01.2016 | ||
IE | 14.03.2016 | ||
LU | 14.03.2016 | ||
CH | 31.03.2016 | ||
LI | 31.03.2016 | ||
BG | 06.04.2016 | ||
NO | 06.04.2016 | ||
GR | 07.04.2016 | ||
IS | 06.05.2016 | ||
PT | 06.05.2016 | ||
Former [2017/07] | AT | 06.01.2016 | |
BE | 06.01.2016 | ||
CZ | 06.01.2016 | ||
DK | 06.01.2016 | ||
EE | 06.01.2016 | ||
ES | 06.01.2016 | ||
FI | 06.01.2016 | ||
HR | 06.01.2016 | ||
IT | 06.01.2016 | ||
LT | 06.01.2016 | ||
LV | 06.01.2016 | ||
MC | 06.01.2016 | ||
NL | 06.01.2016 | ||
PL | 06.01.2016 | ||
RO | 06.01.2016 | ||
RS | 06.01.2016 | ||
SE | 06.01.2016 | ||
SK | 06.01.2016 | ||
SM | 06.01.2016 | ||
IE | 14.03.2016 | ||
LU | 14.03.2016 | ||
CH | 31.03.2016 | ||
LI | 31.03.2016 | ||
NO | 06.04.2016 | ||
GR | 07.04.2016 | ||
IS | 06.05.2016 | ||
PT | 06.05.2016 | ||
Former [2017/03] | AT | 06.01.2016 | |
BE | 06.01.2016 | ||
CZ | 06.01.2016 | ||
DK | 06.01.2016 | ||
EE | 06.01.2016 | ||
ES | 06.01.2016 | ||
FI | 06.01.2016 | ||
HR | 06.01.2016 | ||
IT | 06.01.2016 | ||
LT | 06.01.2016 | ||
LV | 06.01.2016 | ||
MC | 06.01.2016 | ||
NL | 06.01.2016 | ||
PL | 06.01.2016 | ||
RO | 06.01.2016 | ||
RS | 06.01.2016 | ||
SE | 06.01.2016 | ||
SK | 06.01.2016 | ||
SM | 06.01.2016 | ||
LU | 14.03.2016 | ||
NO | 06.04.2016 | ||
GR | 07.04.2016 | ||
IS | 06.05.2016 | ||
PT | 06.05.2016 | ||
Former [2016/50] | AT | 06.01.2016 | |
CZ | 06.01.2016 | ||
DK | 06.01.2016 | ||
EE | 06.01.2016 | ||
ES | 06.01.2016 | ||
FI | 06.01.2016 | ||
HR | 06.01.2016 | ||
IT | 06.01.2016 | ||
LT | 06.01.2016 | ||
LV | 06.01.2016 | ||
MC | 06.01.2016 | ||
NL | 06.01.2016 | ||
PL | 06.01.2016 | ||
RO | 06.01.2016 | ||
RS | 06.01.2016 | ||
SE | 06.01.2016 | ||
SK | 06.01.2016 | ||
SM | 06.01.2016 | ||
LU | 14.03.2016 | ||
BE | 31.03.2016 | ||
NO | 06.04.2016 | ||
GR | 07.04.2016 | ||
IS | 06.05.2016 | ||
PT | 06.05.2016 | ||
Former [2016/49] | AT | 06.01.2016 | |
DK | 06.01.2016 | ||
EE | 06.01.2016 | ||
ES | 06.01.2016 | ||
FI | 06.01.2016 | ||
HR | 06.01.2016 | ||
IT | 06.01.2016 | ||
LT | 06.01.2016 | ||
LV | 06.01.2016 | ||
MC | 06.01.2016 | ||
NL | 06.01.2016 | ||
PL | 06.01.2016 | ||
RS | 06.01.2016 | ||
SE | 06.01.2016 | ||
LU | 14.03.2016 | ||
BE | 31.03.2016 | ||
NO | 06.04.2016 | ||
GR | 07.04.2016 | ||
IS | 06.05.2016 | ||
PT | 06.05.2016 | ||
Former [2016/47] | AT | 06.01.2016 | |
DK | 06.01.2016 | ||
ES | 06.01.2016 | ||
FI | 06.01.2016 | ||
HR | 06.01.2016 | ||
IT | 06.01.2016 | ||
LT | 06.01.2016 | ||
LV | 06.01.2016 | ||
NL | 06.01.2016 | ||
PL | 06.01.2016 | ||
RS | 06.01.2016 | ||
SE | 06.01.2016 | ||
LU | 14.03.2016 | ||
BE | 31.03.2016 | ||
NO | 06.04.2016 | ||
GR | 07.04.2016 | ||
IS | 06.05.2016 | ||
PT | 06.05.2016 | ||
Former [2016/46] | AT | 06.01.2016 | |
DK | 06.01.2016 | ||
ES | 06.01.2016 | ||
FI | 06.01.2016 | ||
HR | 06.01.2016 | ||
IT | 06.01.2016 | ||
LT | 06.01.2016 | ||
LV | 06.01.2016 | ||
NL | 06.01.2016 | ||
PL | 06.01.2016 | ||
RS | 06.01.2016 | ||
SE | 06.01.2016 | ||
BE | 31.03.2016 | ||
NO | 06.04.2016 | ||
GR | 07.04.2016 | ||
IS | 06.05.2016 | ||
PT | 06.05.2016 | ||
Former [2016/39] | AT | 06.01.2016 | |
ES | 06.01.2016 | ||
FI | 06.01.2016 | ||
HR | 06.01.2016 | ||
IT | 06.01.2016 | ||
LT | 06.01.2016 | ||
LV | 06.01.2016 | ||
NL | 06.01.2016 | ||
PL | 06.01.2016 | ||
RS | 06.01.2016 | ||
SE | 06.01.2016 | ||
BE | 31.03.2016 | ||
NO | 06.04.2016 | ||
GR | 07.04.2016 | ||
IS | 06.05.2016 | ||
PT | 06.05.2016 | ||
Former [2016/38] | AT | 06.01.2016 | |
ES | 06.01.2016 | ||
FI | 06.01.2016 | ||
HR | 06.01.2016 | ||
IT | 06.01.2016 | ||
LT | 06.01.2016 | ||
NL | 06.01.2016 | ||
PL | 06.01.2016 | ||
BE | 31.03.2016 | ||
NO | 06.04.2016 | ||
GR | 07.04.2016 | ||
IS | 06.05.2016 | ||
PT | 06.05.2016 | ||
Former [2016/36] | AT | 06.01.2016 | |
ES | 06.01.2016 | ||
FI | 06.01.2016 | ||
HR | 06.01.2016 | ||
IT | 06.01.2016 | ||
LT | 06.01.2016 | ||
NL | 06.01.2016 | ||
PL | 06.01.2016 | ||
BE | 31.03.2016 | ||
NO | 06.04.2016 | ||
GR | 07.04.2016 | ||
Former [2016/35] | ES | 06.01.2016 | |
FI | 06.01.2016 | ||
HR | 06.01.2016 | ||
NL | 06.01.2016 | ||
NO | 06.04.2016 | ||
GR | 07.04.2016 | ||
Former [2016/30] | NL | 06.01.2016 | Documents cited: | Search | [E]WO2012064911 (MERCK SHARP & DOHME [US], et al) [E] 1-17* the whole document * | International search | [Y]WO2006029153 (MERCK & CO INC [US], et al); | [Y]WO2008073251 (MERCK & CO INC [US], et al); | [Y] - CONNER ET AL., "Diverse Functional Motifs within the Three Intracellular Loops of the CGRP1 Receptor", BIOCHEMISTRY, (2006), vol. 45, no. 43, pages 12976 - 12985, XP008135594 DOI: http://dx.doi.org/10.1021/bi0615801 |