blank Quick help
blank Maintenance news

Scheduled maintenance

Regular maintenance outages:
between 05.00 and 05.15 hrs CET (Monday to Sunday).

Other outages
Availability

2022.02.11

More...
blank News flashes

News Flashes

New version of the European Patent Register – SPC proceedings information in the Unitary Patent Register.

2024-07-24

More...
blank Related links

Extract from the Register of European Patents

EP About this file: EP2761026

EP2761026 - CONTINUOUS EXTENSION AND DEBLOCKING IN REACTIONS FOR NUCLEIC ACID SYNTHESIS AND SEQUENCING [Right-click to bookmark this link]
StatusThe application has been refused
Status updated on  01.12.2017
Database last updated on 18.11.2024
Most recent event   Tooltip01.12.2017Refusal of applicationpublished on 03.01.2018  [2018/01]
Applicant(s)For all designated states
Illumina, Inc.
5200 Illumina Way
San Diego, CA 92122 / US
[2014/32]
Inventor(s)01 / MEULEMAN, Wouter
c/o Illumina, Inc.
Legal Department
9885 Towne Centre Drive
San Diego, CA 92121-1975 / US
02 / CRESSINA, Elena
c/o Illumina, Inc.
Legal Department
9885 Towne Centre Drive
San Diego, CA 92121-1975 / US
03 / SMITH, Geoffrey Paul
c/o Illumina, Inc.
Legal Department
9885 Towne Centre Drive
San Diego, CA 92121-1975 / US
04 / JACKSON, Rosamond
c/o Illumina, Inc.
Legal Department
9885 Towne Centre Drive
San Diego, CA 92121-1975 / US
05 / LIU, Ziaohai
c/o Illumina, Inc.
Legal Department
9885 Towne Centre Drive
San Diego, CA 92121-1975 / US
 [2014/32]
Representative(s)Cooley (UK) LLP
22 Bishopsgate
London EC2N 4BQ / GB
[N/P]
Former [2014/32]Heare, Tanya, et al
Venner Shipley LLP
200 Aldersgate
London EC1A 4HD / GB
Application number, filing date12777938.728.09.2012
WO2012GB52406
Priority number, dateUS201161540714P29.09.2011         Original published format: US 201161540714 P
[2014/32]
Filing languageEN
Procedural languageEN
PublicationType: A1 Application with search report
No.:WO2013045939
Date:04.04.2013
Language:EN
[2013/14]
Type: A1 Application with search report 
No.:EP2761026
Date:06.08.2014
Language:EN
The application published by WIPO in one of the EPO official languages on 04.04.2013 takes the place of the publication of the European patent application.
[2014/32]
Search report(s)International search report - published on:EP04.04.2013
ClassificationIPC:C12Q1/68
[2014/32]
CPC:
C12Q1/6874 (EP,US)
C-Set:
C12Q1/6874, C12Q2521/101, C12Q2523/107, C12Q2525/101, C12Q2525/186, C12Q2565/1015 (EP,US)
Designated contracting statesAL,   AT,   BE,   BG,   CH,   CY,   CZ,   DE,   DK,   EE,   ES,   FI,   FR,   GB,   GR,   HR,   HU,   IE,   IS,   IT,   LI,   LT,   LU,   LV,   MC,   MK,   MT,   NL,   NO,   PL,   PT,   RO,   RS,   SE,   SI,   SK,   SM,   TR [2014/32]
TitleGerman:STETIGE AUSDEHNUNG UND ENTBLOCKIERUNG IN REAKTIONEN ZUR NUKLEINSÄURESYNTHESE UND -SEQUENZIERUNG[2014/32]
English:CONTINUOUS EXTENSION AND DEBLOCKING IN REACTIONS FOR NUCLEIC ACID SYNTHESIS AND SEQUENCING[2014/32]
French:ALLONGEMENT CONTINU ET DÉBLOCAGE DANS DES RÉACTIONS DE SYNTHÈSE ET DE SÉQUENÇAGE D'ACIDES NUCLÉIQUES[2014/32]
Entry into regional phase23.04.2014National basic fee paid 
23.04.2014Designation fee(s) paid 
23.04.2014Examination fee paid 
Examination procedure23.04.2014Examination requested  [2014/32]
02.12.2014Amendment by applicant (claims and/or description)
20.02.2015Despatch of a communication from the examining division (Time limit: M04)
13.04.2015Reply to a communication from the examining division
29.01.2016Despatch of a communication from the examining division (Time limit: M04)
08.06.2016Reply to a communication from the examining division
07.07.2017Cancellation of oral proceeding that was planned for 10.07.2017
10.07.2017Date of oral proceedings (cancelled)
16.08.2017Despatch of communication that the application is refused, reason: substantive examination [2018/01]
26.08.2017Application refused, date of legal effect [2018/01]
Divisional application(s)EP17180245.7  / EP3293272
The date of the Examining Division's first communication in respect of the earliest application for which a communication has been issued is  20.02.2015
Fees paidRenewal fee
29.10.2014Renewal fee patent year 03
11.09.2015Renewal fee patent year 04
13.09.2016Renewal fee patent year 05
12.09.2017Renewal fee patent year 06
Penalty fee
Additional fee for renewal fee
30.09.201403   M06   Fee paid on   29.10.2014
Opt-out from the exclusive  Tooltip
competence of the Unified
Patent Court
See the Register of the Unified Patent Court for opt-out data
Responsibility for the accuracy, completeness or quality of the data displayed under the link provided lies entirely with the Unified Patent Court.
Cited inInternational search[I]  - METZKER MICHAEL L, "APPLICATIONS OF NEXT-GENERATION SEQUENCING Sequencing technologies - the next generation", NATURE REVIEWS GENETICS, NATURE PUBLISHING GROUP, GB, (20100101), vol. 11, no. 1, doi:10.1038/NRG2626, ISSN 1471-0056, pages 31 - 46, XP002659622 [I] 1-29 * the whole document *

DOI:   http://dx.doi.org/10.1038/NRG2626
 [I]  - METZKER M L ET AL, "ELECTROPHORETICALLY UNIFORM FLUORESCENT DYES FOR AUTOMATED DNA SEQUENCING", SCIENCE, AMERICAN ASSOCIATION FOR THE ADVANCEMENT OF SCIENCE, WASHINGTON, DC; US, (19960308), vol. 271, no. 5254, doi:10.1126/SCIENCE.271.5254.1420, ISSN 0036-8075, pages 1420 - 1422, XP001181374 [I] 4-29 * Box 1; Fig. 2 *

DOI:   http://dx.doi.org/10.1126/science.271.5254.1420
 [I]  - CARL W FULLER ET AL, "The challenges of sequencing by synthesis", NATURE BIOTECHNOLOGY, (20091101), vol. 27, no. 11, doi:10.1038/nbt.1585, ISSN 1087-0156, pages 1013 - 1023, XP055013694 [I] 4-29 * the whole document *

DOI:   http://dx.doi.org/10.1038/nbt.1585
 [I]  - J. GUO ET AL, "Four-color DNA sequencing with 3'-O-modified nucleotide reversible terminators and chemically cleavable fluorescent dideoxynucleotides", PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES, (20080101), vol. 105, no. 27, doi:10.1073/pnas.0804023105, ISSN 0027-8424, pages 9145 - 9150, XP055013741 [I] 4-29 * the whole document *

DOI:   http://dx.doi.org/10.1073/pnas.0804023105
ExaminationWO2004018497
    - BENTLEY DAVID R ET AL, "Accurate whole human genome sequencing using reversible terminator chemistry", NATURE, NATURE PUBLISHING GROUP, UNITED KINGDOM, (20081106), vol. 456, no. 7218, doi:10.1038/NATURE07517, ISSN 0028-0836, pages 53 - 59, XP002558230

DOI:   http://dx.doi.org/10.1038/nature07517
    - J. Guo ET AL, "Four-color DNA sequencing with 3'-O-modified nucleotide reversible terminators and chemically cleavable fluorescent dideoxynucleotides", Proceedings of the National Academy of Sciences, (20080101), vol. 105, no. 27, doi:10.1073/pnas.0804023105, ISSN 0027-8424, pages 9145 - 9150, XP055013741

DOI:   http://dx.doi.org/10.1073/pnas.0804023105
    - TURCATTI G ET AL, "A new class of cleavable fluorescent nucleotides: synthesis and optimization as reversible terminators for DNA sequencing by synthesis", NUCLEIC ACIDS RESEARCH, OXFORD UNIVERSITY PRESS, GB, vol. 36, no. 4, doi:10.1093/NAR/GKN021, ISSN 0305-1048, (20080301), pages E25 - 1, (20080207), XP002631196

DOI:   http://dx.doi.org/10.1093/NAR/GKN021
by applicantWO9106678
 US5641658
 WO9859066
 US6090592
 US6172218
 US6232465
 US6306597
 US6664079
 US6737236
 WO2005010145
 US2005042648
 US2005079510
 US2005130173
 WO2005065814
 US2005244870
 US6969488
 US7057026
 US2006240439
 WO2007010251
 US2007099208
 US2007128624
 US7259258
 WO2007123744
 US7329860
 US2008037008
 US7375234
 US7414116
 US7427678
 US7427673
 US2009026082
 US2009127589
 US7541444
 US2010092957
 US2010111768
 US2010137143
 US2010173303
 US2010279882
 US2010282617
 US2011059865
    - METH. ENZYMOL., (1998), vol. 291, pages 307 - 347
    - HAUGLAND, Molecular Probes Handbook
    - The Synthegen catalog, HOUSTON, TX
    - FERSHT, A. R., Enzyme Structure and Mechanism, W. H. FREEMAN & CO., (1985), page 350
    - BORDO ET AL., JMOL BIOL, (1991), vol. 217, pages 721 - 729
    - HAYES ET AL., PROC NATL ACAD SCI, USA, (2002), vol. 99, pages 15926 - 15931
    - DRESSMAN ET AL., PROC. NATL. ACAD. SCI. USA, (2003), vol. 100, pages 8817 - 8822
    - MITRA; CHURCH, NUCLEIC ACIDS RES., (1999), vol. 27, page E34
    - ADESSI, C. ET AL., NUCLEIC ACIDS RES., (2000), vol. 28, page E87
    - FEDURCO ET AL., NUCLEIC ACIDS RES., (2006), vol. 34, page E22
    - GIRAUD ET AL., BIOMEDICAL OPTICS EXPRESS, (2010), vol. 1, pages 1302 - 1308
    - STOPPA ET AL., IEEE EUROPEAN SOLID-STATE DEVICE CONFERENCE (ESSCIRC, (2009), pages 204 - 207
The EPO accepts no responsibility for the accuracy of data originating from other authorities; in particular, it does not guarantee that it is complete, up to date or fit for specific purposes.