blank Quick help
blank Maintenance news

Scheduled maintenance

Regular maintenance outages:
between 05.00 and 05.15 hrs CET (Monday to Sunday).

Other outages
Availability

2022.02.11

More...
blank News flashes

News Flashes

New version of the European Patent Register – SPC proceedings information in the Unitary Patent Register.

2024-07-24

More...
blank Related links

Release notes
European Patent Register Assistant
European Patent Register Resource Book
European Patent Register – pocket guide
FAQ - European Patent Register
Federated Register (Flyer)
Global Dossier (Flyer)
Register events
Deep link coverage
Federated Register content
The Patent Information Tour
Fair use charter

Extract from the Register of European Patents

EP About this file: EP2709975

EP2709975 - PRENYLATED HYDROXYSTILBENES [Right-click to bookmark this link]
StatusNo opposition filed within time limit
Status updated on  18.11.2022
Database last updated on 18.01.2025
FormerThe patent has been granted
Status updated on  10.12.2021
FormerGrant of patent is intended
Status updated on  27.07.2021
FormerExamination is in progress
Status updated on  25.06.2021
FormerGrant of patent is intended
Status updated on  28.02.2021
FormerExamination is in progress
Status updated on  23.03.2018
Most recent event   Tooltip06.09.2024Lapse of the patent in a contracting state
New state(s): MT		published on 09.10.2024  [2024/41]
Applicant(s)For all designated states
Kynan Duke IP, LLC
2307 Princess Ann Street
Greensboro, NC 27408 / US
[2021/40]
Former [2014/13]For all designated states
THE UNIVERSITY OF SYDNEY
Sydney, NSW 2006 / AU
Inventor(s)01 / DUKE, Colin Charles
19 Titania Street
Randwick, NSW 2031 / AU
02 / TRAN, Van Hoan
45 The Esplanade
Guilford, NSW 2161 / AU
03 / DUKE, Rujee Kyokajee
19 Titania Street
Randwick, NSW 2031 / AU
 [2014/13]
Representative(s)Mewburn Ellis LLP
Aurora Building
Counterslip
Bristol BS1 6BX / GB
[2022/02]
Former [2014/13]Oxley, Rachel Louise, et al
Mewburn Ellis LLP 33 Gutter Lane London
EC2V 8AS / GB
Application number, filing date12779889.004.05.2012
[2022/02]
WO2012AU00482
Priority number, dateAU2011090166304.05.2011         Original published format: AU 2011901663
[2014/13]
Filing languageEN
Procedural languageEN
PublicationType: A1 Application with search report
No.:WO2012149608
Date:08.11.2012
Language:EN
[2012/45]
Type: A1 Application with search report 
No.:EP2709975
Date:26.03.2014
Language:EN
The application published by WIPO in one of the EPO official languages on 08.11.2012 takes the place of the publication of the European patent application.
[2014/13]
Type: B1 Patent specification 
No.:EP2709975
Date:12.01.2022
Language:EN
[2022/02]
Search report(s)International search report - published on:AU08.11.2012
(Supplementary) European search report - dispatched on:EP19.11.2014
ClassificationIPC:C07C39/205, C07C39/215, A61P31/00, A61P35/02, A61K31/03
[2014/13]
CPC:
A61P17/00 (EP); C07C39/205 (KR); C07C43/23 (EP,CN,US);
C07C43/253 (US); A61K31/03 (KR); A61K31/05 (CN);
A61K31/09 (CN); A61P29/00 (EP); A61P31/00 (EP);
A61P31/04 (EP); A61P31/10 (EP); A61P35/00 (EP);
A61P35/02 (EP); A61P37/04 (EP); A61P37/06 (EP);
C07C37/055 (US); C07C39/21 (EP,CN,US); C07C39/215 (KR,US);
C07C41/01 (US); C07C67/293 (US); C07C67/297 (US) (-)
Designated contracting statesAL,   AT,   BE,   BG,   CH,   CY,   CZ,   DE,   DK,   EE,   ES,   FI,   FR,   GB,   GR,   HR,   HU,   IE,   IS,   IT,   LI,   LT,   LU,   LV,   MC,   MK,   MT,   NL,   NO,   PL,   PT,   RO,   RS,   SE,   SI,   SK,   SM,   TR [2014/13]
Extension statesBANot yet paid
MENot yet paid
TitleGerman:PRENYLIERTE HYDROXYSTILBENE[2014/13]
English:PRENYLATED HYDROXYSTILBENES[2014/13]
French:HYDROXYSTILBÈNES PRÉNYLÉS[2014/13]
Entry into regional phase29.11.2013National basic fee paid 
29.11.2013Search fee paid 
29.11.2013Designation fee(s) paid 
29.11.2013Examination fee paid 
Examination procedure27.02.2013Request for preliminary examination filed
International Preliminary Examining Authority: AU
29.11.2013Examination requested  [2014/13]
11.06.2015Amendment by applicant (claims and/or description)
26.03.2018Despatch of a communication from the examining division (Time limit: M04)
26.07.2018Reply to a communication from the examining division
23.10.2018Despatch of a communication from the examining division (Time limit: M04)
28.02.2019Reply to a communication from the examining division
06.07.2020Despatch of a communication from the examining division (Time limit: M04)
28.10.2020Reply to a communication from the examining division
01.03.2021Communication of intention to grant the patent
23.06.2021Disapproval of the communication of intention to grant the patent by the applicant or resumption of examination proceedings by the EPO
28.07.2021Communication of intention to grant the patent
02.12.2021Fee for grant paid
02.12.2021Fee for publishing/printing paid
02.12.2021Receipt of the translation of the claim(s)
Divisional application(s)The date of the Examining Division's first communication in respect of the earliest application for which a communication has been issued is  26.03.2018
Opposition(s)13.10.2022No opposition filed within time limit [2022/51]
Fees paidRenewal fee
26.05.2014Renewal fee patent year 03
21.05.2015Renewal fee patent year 04
30.03.2016Renewal fee patent year 05
25.05.2017Renewal fee patent year 06
25.05.2018Renewal fee patent year 07
08.05.2019Renewal fee patent year 08
31.03.2020Renewal fee patent year 09
17.05.2021Renewal fee patent year 10
Opt-out from the exclusive  Tooltip
competence of the Unified
Patent Court		 See the Register of the Unified Patent Court for opt-out data
Responsibility for the accuracy, completeness or quality of the data displayed under the link provided lies entirely with the Unified Patent Court.
Lapses during opposition  TooltipHU04.05.2012
AL12.01.2022
CY12.01.2022
CZ12.01.2022
EE12.01.2022
HR12.01.2022
LT12.01.2022
LV12.01.2022
MC12.01.2022
MK12.01.2022
MT12.01.2022
PL12.01.2022
RO12.01.2022
RS12.01.2022
SI12.01.2022
SK12.01.2022
SM12.01.2022
BG12.04.2022
LU04.05.2022
IS12.05.2022
[2024/41]
Former [2024/22]HU04.05.2012
AL12.01.2022
CY12.01.2022
CZ12.01.2022
EE12.01.2022
HR12.01.2022
LT12.01.2022
LV12.01.2022
MC12.01.2022
MK12.01.2022
PL12.01.2022
RO12.01.2022
RS12.01.2022
SI12.01.2022
SK12.01.2022
SM12.01.2022
BG12.04.2022
LU04.05.2022
IS12.05.2022
Former [2024/20]HU04.05.2012
AL12.01.2022
CY12.01.2022
CZ12.01.2022
EE12.01.2022
HR12.01.2022
LT12.01.2022
LV12.01.2022
MC12.01.2022
PL12.01.2022
RO12.01.2022
RS12.01.2022
SI12.01.2022
SK12.01.2022
SM12.01.2022
BG12.04.2022
LU04.05.2022
IS12.05.2022
Former [2024/18]HU04.05.2012
AL12.01.2022
CZ12.01.2022
EE12.01.2022
HR12.01.2022
LT12.01.2022
LV12.01.2022
MC12.01.2022
PL12.01.2022
RO12.01.2022
RS12.01.2022
SI12.01.2022
SK12.01.2022
SM12.01.2022
BG12.04.2022
LU04.05.2022
IS12.05.2022
Former [2023/10]AL12.01.2022
CZ12.01.2022
EE12.01.2022
HR12.01.2022
LT12.01.2022
LV12.01.2022
MC12.01.2022
PL12.01.2022
RO12.01.2022
RS12.01.2022
SI12.01.2022
SK12.01.2022
SM12.01.2022
BG12.04.2022
LU04.05.2022
IS12.05.2022
Former [2023/08]AL12.01.2022
CZ12.01.2022
EE12.01.2022
HR12.01.2022
LT12.01.2022
LV12.01.2022
MC12.01.2022
PL12.01.2022
RO12.01.2022
RS12.01.2022
SK12.01.2022
SM12.01.2022
BG12.04.2022
LU04.05.2022
IS12.05.2022
Former [2023/06]AL12.01.2022
CZ12.01.2022
EE12.01.2022
HR12.01.2022
LT12.01.2022
LV12.01.2022
MC12.01.2022
PL12.01.2022
RO12.01.2022
RS12.01.2022
SK12.01.2022
SM12.01.2022
BG12.04.2022
IS12.05.2022
Former [2023/01]AL12.01.2022
CZ12.01.2022
EE12.01.2022
HR12.01.2022
LT12.01.2022
LV12.01.2022
PL12.01.2022
RO12.01.2022
RS12.01.2022
SK12.01.2022
SM12.01.2022
BG12.04.2022
IS12.05.2022
Former [2022/49]CZ12.01.2022
EE12.01.2022
HR12.01.2022
LT12.01.2022
LV12.01.2022
PL12.01.2022
RO12.01.2022
RS12.01.2022
SK12.01.2022
SM12.01.2022
BG12.04.2022
IS12.05.2022
Former [2022/48]CZ12.01.2022
EE12.01.2022
HR12.01.2022
LT12.01.2022
LV12.01.2022
PL12.01.2022
RO12.01.2022
RS12.01.2022
SM12.01.2022
BG12.04.2022
IS12.05.2022
Former [2022/47]HR12.01.2022
LT12.01.2022
LV12.01.2022
PL12.01.2022
RO12.01.2022
RS12.01.2022
SM12.01.2022
BG12.04.2022
IS12.05.2022
Former [2022/42]HR12.01.2022
LT12.01.2022
LV12.01.2022
PL12.01.2022
RS12.01.2022
BG12.04.2022
IS12.05.2022
Former [2022/36]HR12.01.2022
LT12.01.2022
LV12.01.2022
PL12.01.2022
RS12.01.2022
BG12.04.2022
Former [2022/35]HR12.01.2022
LT12.01.2022
RS12.01.2022
BG12.04.2022
Former [2022/33]LT12.01.2022
Documents cited:Search[X]CN1566054  ;
 [X]WO03010121  (PACIFIC CORP [KR], et al) [X] 4,13 * page 9, line 11 - page 10, line 15; claims 1,5 *;
 [X]US2003125377  (KINGHORN ALAN DOUGLAS [US], et al) [X] 4 * Compound 6 in paragraph 35 and on p.8, bottom left-hand corner *;
 [X]  - CHENG-PO HUANG ET AL, "Arachidin-1, a Peanut Stilbenoid, Induces Programmed Cell Death in Human Leukemia HL-60 Cells", JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY, (20101208), vol. 58, no. 23, doi:10.1021/jf102993j, ISSN 0021-8561, pages 12123 - 12129, XP055149891 [X] 1,3 * Whole document in respect of compounds Ara-1 and Ara-3 *

DOI:   http://dx.doi.org/10.1021/jf102993j
 [X]  - REAXYS, Elsevier Properties SA, Database accession no. 7355532, XP002731930 [X] 4 * Reaxys Registry Nos. 7355532, 7355111 *
    [ ] - PHYTOCHEMISTRY, (1976), vol. 15, pages 2006 - 2008
 [X]  - BANKIM PATEL ET AL, "Inhibition of cyclo-oxygenase-2 expression in mouse macrophages by 4-(3-methyl-but-1-enyl)-3,5,3',4'-tetrahydroxystilbene, a resveratrol derivative from peanuts", PHYTOTHERAPY RESEARCH, (2005), vol. 19, no. 6, doi:10.1002/ptr.1698, ISSN 0951-418X, pages 552 - 555, XP055149972 [X] 1 * Whole document in view of compound BS2 *

DOI:   http://dx.doi.org/10.1002/ptr.1698
 [X]  - FUKAI T ET AL, "CYTOTOXIC ACTIVITY OF LOW MOLECULAR WEIGHT POLYPHENOLS AGAINST HUMAN ORAL TUMOR CELL LINES", ANTICANCER RESEARCH - INTERNATIONAL JOURNAL OF CANCER RESEARCH AND TREATMENT, INTERNATIONAL INSTITUTE OF ANTICANCER RESEARCH, GR, (2000), vol. 20, no. 4, ISSN 0250-7005, pages 2525 - 2536, XP001016407 [X] 1 * figure 1; table II; compounds 95,96 *
 [X]  - F. ORSINI ET AL, "Resveratrol Derivatives and Their Role as Potassium Channels Modulators", JOURNAL OF NATURAL PRODUCTS, (20040220), vol. 67, no. 3, doi:10.1021/np0303153, ISSN 0163-3864, pages 421 - 426, XP055149843 [X] 12 * Last paragraph on p.422; nmr data on compound 13 on p.424;; compound 13 *

DOI:   http://dx.doi.org/10.1021/np0303153
 [X]  - Genjiro Kusano ET AL, "The Japanese Society of Pharmacognosy NII-Electronic Library Service Studies on Index Compounds for HPLC Analysis of Glycyrthiza JZdvescens Growing in [thrkey", Natural Medicines, (2002), pages 29 - 135, URL: http://ci.nii.ac.jp/lognavi?name=nels&lang=en&type=pdf&id=ART0009809307, (20141030), XP055149856 [X] 12 * figure 2; compound 4 *
 [X]  - DATABASE WPI, 0, Derwent World Patents Index, vol. 2005, no. 75, Database accession no. 2005-726141, XP002731931 & CN1566054 A 20050119 (CHINESE ACAD MEDICAL SCI) [X] 1 * Compounds c and d in the table bridging pp.7/8 *
 [X]  - VICTOR S. SOBOLEV ET AL, "Biological Activity of Peanut ( Arachis hypogaea ) Phytoalexins and Selected Natural and Synthetic Stilbenoids", JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY, (20110211), vol. 59, no. 5, doi:10.1021/jf104742n, ISSN 0021-8561, pages 1673 - 1682, XP055149735 [X] 1 * Whole document in respect of Arachidins 1-3 *

DOI:   http://dx.doi.org/10.1021/jf104742n
 [X]  - BAMBANG DJOKO ET AL, "Characterization of Immunological Activities of Peanut Stilbenoids, Arachidin-1, Piceatannol, and Resveratrol on Lipopolysaccharide-Induced Inflammation of RAW 264.7 Macrophages", JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY, (20070223), vol. 55, no. 6, doi:10.1021/jf062741a, ISSN 0021-8561, pages 2376 - 2383, XP055149740 [X] 1 * Whole document in respect of Arachidin-1 in fig. 1 *

DOI:   http://dx.doi.org/10.1021/jf062741a
 [I]  - EHRMAN T M ET AL, "In silico search for multi-target anti-inflammatories in Chinese herbs and formulas", BIOORGANIC & MEDICINAL CHEMISTRY, PERGAMON, GB, vol. 18, no. 6, doi:10.1016/J.BMC.2010.01.070, ISSN 0968-0896, (20100315), pages 2204 - 2218, (20100208), XP026941352 [I] 1 * Gancaonin in fig. 5 *

DOI:   http://dx.doi.org/10.1016/j.bmc.2010.01.070
International search[X]JPH0717859  (TSUMURA & CO);
 [X]WO03009807  (GALILEO LAB INC [US]);
 [X]GB2411353  (UNIV HERTFORDSHIRE [GB]);
 [X]CN101070274  (UNIV FUDAN [CN]);
 [X]WO2009012910  (UNIV DEGLI STUDI MILANO [IT], et al);
 [X]  - SIRACUSA, L. ET AL., "Phytocomplexes from liquorice (Glycyrrhiza glabra L.) leaves- Chemical characterization and evaluation of their antioxidant, anti-genotoxic and antiinflammatory activity", FITOTERAPIA (2011), (20110131), vol. 82, no. 4, pages 546 - 556, XP028197880

DOI:   http://dx.doi.org/10.1016/j.fitote.2011.01.009
    [ ] - REGISTRY, STN, Database accession no. 525585-29-9
    [ ] - REGISTRY, Database accession no. 1352058-70-8
 [X]  - MUNIGUNTI, R. ET AL., "Screening of natural compounds for ligands to PfTrxR by ultrafiltration and LC-MS based binding assay", JOURNAL OF PHARMACEUTICAL AND BIOMEDICAL ANALYSIS (2011), (20110203), vol. 55, no. 2, pages 265 - 271, XP028172804

DOI:   http://dx.doi.org/10.1016/j.jpba.2011.01.033
    [ ] - REGISTRY, STN, Database accession no. 1083192-76-0
    [ ] - REGISTRY, STN, Database accession no. 1136618-10-4
 [X]  - ZHANG, WENJUN. ET AL., "QSAR study of cinnamylphenol derivatives as EBV-EA inhibitors", JISUANJI YU YINGYONG HUAXUE, (2009), vol. 26, no. 12, pages 1598 - 1602, XP008171027
    [ ] - REGISTRY, Database accession no. 945919-58-4, URL: STN
    [ ] - REGISTRY, Database accession no. 945919-59-5, URL: STN
    [ ] - REGISTRY, Database accession no. 945919-60-8
    [ ] - REGISTRY, Database accession no. 945919-61-9
 [X]  - REGISTRY, (20080615), Database accession no. 1028254-67-2, XP003030270
by applicantJPH0717859
 WO03009807
 WO03010121
 US2003125377
 CN1566054
 GB2411353
 WO2009012910
    - CHENG-PO HUANG et al., Journal of Agricultural and Food Chem., (20100000), vol. 58, pages 12123 - 12129
    - BANKIM PATEL et al., Phytotherapy Research, (20050000), vol. 19, pages 552 - 555
    - VICTORS. SOBOLEV et al., Journal of agricultural and food chemistry, (20110000), vol. 59, pages 1673 - 1682
    - SIRACUSA, L. et al., Fitoterapia, (20110000), vol. 82, pages 546 - 556
    - BAMBANG DJOKO et al., Journal of Agricultural and Food Chemistry, (20070000), vol. 55, pages 2376 - 2383
    - GENJIRO KUSANO et al., Natual Medicines, (20020000), pages 29 - 135
    - FUKAI T et al., Anticancer Research, (20000000), vol. 20, pages 2525 - 2536
    - DENMARK, E.; REGENS, C. S.; TETSUYA, K., J. of Am. Chem. Soc., (20070000), vol. 129, pages 2774 - 2276
    - ALI, I. A. I.; FATHALLA, W., Heteroatom Chemistry, (20060000), vol. 17, pages 280 - 288
    - KROHN, K.; THIEM, J., J. Chem. Soc., Perkin Trans., (19770000), vol. 1, pages 1186 - 1190
    - SOERME, P.; ARNOUX, P.; KAHL-KNUTSSON, B.; LEFFLER, H.; RINI, J. M.; NILSSON, U. J., J. Am. Chem. Soc., (20050000), vol. 127, pages 1737 - 1743
    - ANDRUS, M. B.; LIU, J.; MEREDITH, E. L.; NARTEY, E., Tetrahedron Lett., (20030000), vol. 44, pages 4819 - 4822
    - RAO, M. L. N.; AWASTHI, D. K.; BANERJEE, D., Tetrahedron Lett., (20100000), vol. 51, pages 1979 - 1981
    - YANG, P.-Y.; ZHOU, Y.-G., Tetrahedron Asymmetry, (20040000), vol. 15, pages 1145 - 1149
    - ROONEY, J. M., Journal of Macromolecular Science, Part A, (19860000), vol. 23, pages 823 - 829
    - BATSOMBOON, P.; PHAKHODEE, W.; RUCHIRAWAT, S.; PLOYPRADITH, P., J. Org. Chem., (20090000), vol. 74, pages 4009 - 4012
    - MICHAN, S.; SINCLAIR D., Biochem. J., (20070000), vol. 404, pages 1 - 13
    - YAMAMOTO H.; SCHOONJANS K.; AUWERX J., Mol. Endocrinol., (20070000), vol. 21, pages 1745 - 1755
The EPO accepts no responsibility for the accuracy of data originating from other authorities; in particular, it does not guarantee that it is complete, up to date or fit for specific purposes.