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Extract from the Register of European Patents

EP About this file: EP2718486

EP2718486 - METHODS AND COMPOSITIONS OF PREDICTING ACTIVITY OF RETINOID X RECEPTOR MODULATOR [Right-click to bookmark this link]
StatusThe application has been refused
Status updated on  26.01.2018
Database last updated on 03.10.2024
Most recent event   Tooltip26.01.2018Refusal of applicationpublished on 28.02.2018  [2018/09]
Applicant(s)For all designated states
Denovo Biopharma (Hangzhou) Ltd. Co.
452 6th Avenue, Building 2
Room A1405-A1412
Hangzhou Economic and
Technological Development Zone
Hangzhou, Zhejiang 310018 / CN
[2014/16]
Inventor(s)01 / LUO, Wen
5003 Ruette De Mer
San Diego, CA 92130 / US
 [2014/16]
Representative(s)Witte, Weller & Partner Patentanwälte mbB
Postfach 10 54 62
70047 Stuttgart / DE
[N/P]
Former [2014/16]Witte, Weller & Partner Patentanwälte mbB
Königstrasse 5
70173 Stuttgart / DE
Application number, filing date12797326.107.06.2012
WO2012US41379
Priority number, dateUS201161494773P08.06.2011         Original published format: US 201161494773 P
[2014/16]
Filing languageEN
Procedural languageEN
PublicationType: A2 Application without search report
No.:WO2012170704
Date:13.12.2012
Language:EN
[2012/50]
Type: A2 Application without search report 
No.:EP2718486
Date:16.04.2014
Language:EN
The application published by WIPO in one of the EPO official languages on 13.12.2012 takes the place of the publication of the European patent application.
[2014/16]
Search report(s)International search report - published on:RU31.01.2013
(Supplementary) European search report - dispatched on:EP03.12.2014
ClassificationIPC:C40B40/06, C12N15/12, C12Q1/68, G01N33/50
[2014/16]
CPC:
C12Q1/6886 (EP,US); A61P25/00 (EP); A61P25/28 (EP);
A61P3/00 (EP); A61P3/10 (EP); A61P35/00 (EP);
A61P43/00 (EP); C07K14/70567 (EP,US); G16C20/30 (EP,US);
G16H50/20 (EP,US); C12Q2600/106 (EP,US); C12Q2600/136 (US);
C12Q2600/156 (EP,US); C12Q2600/178 (US); C40B30/04 (US);
G01N2500/00 (EP,US); G01N2800/52 (EP,US) (-)
Designated contracting statesAL,   AT,   BE,   BG,   CH,   CY,   CZ,   DE,   DK,   EE,   ES,   FI,   FR,   GB,   GR,   HR,   HU,   IE,   IS,   IT,   LI,   LT,   LU,   LV,   MC,   MK,   MT,   NL,   NO,   PL,   PT,   RO,   RS,   SE,   SI,   SK,   SM,   TR [2014/16]
TitleGerman:VERFAHREN UND ZUSAMMENSETZUNGEN ZUR VORHERSAGE DER AKTIVITÄT DES RETINOID-X-REZEPTOR-MODULATORS[2014/16]
English:METHODS AND COMPOSITIONS OF PREDICTING ACTIVITY OF RETINOID X RECEPTOR MODULATOR[2014/16]
French:PROCÉDÉS ET COMPOSITIONS POUR LA PRÉDICTION DE L'ACTIVITÉ D'UN MODULATEUR DU RÉCEPTEUR X DES RÉTINOÏDES[2014/16]
Entry into regional phase11.12.2013National basic fee paid 
11.12.2013Search fee paid 
11.12.2013Designation fee(s) paid 
11.12.2013Examination fee paid 
Examination procedure11.12.2013Examination requested  [2014/16]
25.06.2015Amendment by applicant (claims and/or description)
18.12.2015Despatch of a communication from the examining division (Time limit: M06)
24.06.2016Reply to a communication from the examining division
27.09.2017Cancellation of oral proceeding that was planned for 04.10.2017
04.10.2017Date of oral proceedings (cancelled)
10.10.2017Despatch of communication that the application is refused, reason: substantive examination [2018/09]
20.10.2017Application refused, date of legal effect [2018/09]
Divisional application(s)The date of the Examining Division's first communication in respect of the earliest application for which a communication has been issued is  18.12.2015
Fees paidRenewal fee
12.06.2014Renewal fee patent year 03
10.06.2015Renewal fee patent year 04
10.06.2016Renewal fee patent year 05
16.06.2017Renewal fee patent year 06
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Documents cited:Search[XI]  - KOJIMA T ET AL, "Determination of genomic breakpoints in an epileptic patient using genotyping array", BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS, ACADEMIC PRESS INC. ORLANDO, FL, US, vol. 341, no. 3, doi:10.1016/J.BBRC.2006.01.032, ISSN 0006-291X, (20060317), pages 792 - 796, (20060317), XP024923853 [X] 1-7,9 * page 792, right col.; abstract; * [I] 8,9

DOI:   http://dx.doi.org/10.1016/j.bbrc.2006.01.032
 [XI]  - J L MCCLAY ET AL, "Genome-wide pharmacogenomic analysis of response to treatment with antipsychotics", MOLECULAR PSYCHIATRY, (20090901), vol. 16, no. 1, doi:10.1038/mp.2009.89, ISSN 1359-4184, pages 76 - 85, XP055153055 [X] 10,14 * abstract * * page 78, left; * [I] 11,12,15

DOI:   http://dx.doi.org/10.1038/mp.2009.89
 [A]  - HAN J-Y ET AL, "Associations of ABCB1, ABCC2, and ABCG2 polymorphisms with irinotecan-pharmacokinetics and clinical outcome in patients with advanced non-small cell lung cancer", CANCER, AMERICAN CANCER SOCIETY, PHILADELPHIA, PA, US, vol. 110, no. 1, doi:10.1002/CNCR.22760, ISSN 0008-543X, (20070701), pages 138 - 147, (20070529), XP002688160 [A] 1-15 * the whole document *

DOI:   http://dx.doi.org/10.1002/cncr.22760
 [A]  - SHU-ZHEN WEI ET AL, "Predictive value of ERCC1 and XPD polymorphism in patients with advanced non-small cell lung cancer receiving platinum-based chemotherapy: a systematic review and meta-analysis", MEDICAL ONCOLOGY, (20100209), vol. 28, no. 1, doi:10.1007/s12032-010-9443-1, ISSN 1357-0560, pages 315 - 321, XP055153000 [A] 1-15 * the whole document *

DOI:   http://dx.doi.org/10.1007/s12032-010-9443-1
 [XP]  - LUO WEN ET AL, "Identification of polymorphisms associated with hypertriglyceridemia and prolonged survival induced by bexarotene in treating non-small cell lung cancer", ANTICANCER RESEARCH GREECE,, (20111201), vol. 31, no. 6, ISSN 1791-7530, pages 2303 - 2311, XP009159180 [XP] 1-15 * the whole document *
International search[X]WO2011056688  (CARIS LIFE SCIENCES INC [US], et al);
 [Y]US2008280955  (MCCAMISH MARK A [US]);
 [A]  - ARDLIE K.G. ET AL., "Patterns of linkage disequilibrium in the human genome.", NATURE REVIEWS GENETICS, (2002), vol. 3, no. 4, pages 299 - 309, XP055137661

DOI:   http://dx.doi.org/10.1038/nrg777
Examination   - Affymetrix, "SNPs on the Affymetrix 500K array", (20060101), URL: www, (20161209), XP055327577
The EPO accepts no responsibility for the accuracy of data originating from other authorities; in particular, it does not guarantee that it is complete, up to date or fit for specific purposes.