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EP About this file: EP2717865

EP2717865 - METHODS AND COMPOSITIONS FOR TREATING BRAIN CANCER [Right-click to bookmark this link]
Status	The application is deemed to be withdrawn Status updated on 29.04.2016 Database last updated on 03.10.2024
Most recent event Tooltip	29.04.2016	Application deemed to be withdrawn	published on 01.06.2016 [2016/22]
Applicant(s)	For all designated states Golden Biotechnology Corporation 15F, No.27-6, Sec.2 Jhong-Jheng E.Rd. Danshuei New Taipei City / TW
	[2014/16]
Inventor(s)	01 / LIU, Sheng-Yung 15F, No. 27-6 Sec. 2 Jhong-Jheng E. Rd. Danshuei New Taipei City / TW
	02 / HWANG, San-Bao 15F, No. 27-6 Sec. 2 Jhong-Jheng E. Rd. Danshuei NewTaipei City / TW
	03 / WEN, Wu-Che 15F, No. 27-6 Sec. 2 Jhong-Jheng E. Rd. Danshuei New Taipei City / TW
	[2014/16]
Representative(s)	HGF 4th Floor Merchant Exchange 17-19 Whitworth Street West Manchester M1 5WG / GB
	[N/P]
Former [2014/16]	Harrison Goddard Foote LLP 4th Floor Merchant Exchange 17-19 Whitworth Street West Manchester M1 5WG / GB
Application number, filing date	12797582.9	07.06.2012
	WO2012US41401
Priority number, date	US201161495875P	10.06.2011 Original published format: US 201161495875 P
	[2014/16]
Filing language	EN
Procedural language	EN
Publication	Type:	A2 Application without search report
	No.:	WO2012170720
	Date:	13.12.2012
	Language:	EN
	[2012/50]
	Type:	A2 Application without search report
	No.:	EP2717865
	Date:	16.04.2014
	Language:	EN
	The application published by WIPO in one of the EPO official languages on 13.12.2012 takes the place of the publication of the European patent application.
	[2014/16]
Search report(s)	International search report - published on:	KR	11.04.2013
	(Supplementary) European search report - dispatched on:	EP	10.10.2014
Classification	IPC:	C07C49/517, C07C323/22, A61K31/122, A61K31/10, A61P35/00	[2014/45]
	CPC:	A61K31/122 (EP,KR,US); A61K31/12 (KR); A61K31/19 (US); A61P25/28 (EP); A61P35/00 (EP)
	Former IPC [2014/16]	A61K31/122, A61K31/12, A61P35/00
Designated contracting states	AL, AT, BE, BG, CH, CY, CZ, DE, DK, EE, ES, FI, FR, GB, GR, HR, HU, IE, IS, IT, LI, LT, LU, LV, MC, MK, MT, NL, NO, PL, PT, RO, RS, SE, SI, SK, SM, TR [2014/16]
Title	German:	VERFAHREN UND ZUSAMMENSETZUNGEN ZUR BEHANDLUNG VON HIRNKREBS	[2014/16]
	English:	METHODS AND COMPOSITIONS FOR TREATING BRAIN CANCER	[2014/16]
	French:	MÉTHODES ET COMPOSITIONS POUR LE TRAITEMENT DU CANCER DU CERVEAU	[2014/16]
Entry into regional phase	09.01.2014	National basic fee paid
	09.01.2014	Search fee paid
	09.01.2014	Designation fee(s) paid
	09.01.2014	Examination fee paid
Examination procedure	09.01.2014	Examination requested [2014/16]
	28.04.2015	Amendment by applicant (claims and/or description)
	05.01.2016	Application deemed to be withdrawn, date of legal effect [2016/22]
	27.01.2016	Despatch of communication that the application is deemed to be withdrawn, reason: renewal fee not paid in time [2016/22]
Fees paid	Renewal fee
	20.06.2014	Renewal fee patent year 03
	Penalty fee
	Additional fee for renewal fee
	30.06.2015	04 M06 Not yet paid
Opt-out from the exclusive Tooltip competence of the Unified Patent Court	See the Register of the Unified Patent Court for opt-out data
	Responsibility for the accuracy, completeness or quality of the data displayed under the link provided lies entirely with the Unified Patent Court.
Documents cited:	Search	[Y]US2008260695 (LU KUNG-MING [TW]) [Y] 1-15 * Extracts of Anthrodia Camphorata for the treatment of cancers of different types, including brain cancer and neuroblastoma: see paragraph 7 last line, paragraph 26, claims and examples *;
		[Y]US2007116787 (YAO CHIH-JUNG [TW], et al) [Y] 1-15 * Extracts of Anthrodia Camphorata for the treatment of brain cancer: see claims 1, 10 and paragraphs 27-28 *;
		[Y]US7342137 (LIU SHENG-YUN [TW], et al) [Y] 1-15 * Antroquinonol, the preferred compound of the present application, for use in the treatment of different cancers, including breast, hepatic and prosate cancers: see column 2, lines 29-65; column 3, lines 5-15; examples, and claims *;
		[Y] - Hsieh Wan-Yu et al, "Abstract #3676: Antroquinonol inhibits tumorgenesis and metastasis in highly invasive non-small-cell lung cancer cells", (20090421), 100th AACR Annual Meeting- Apr 18-22, 2009; Denver, CO, URL: http://www.aacrmeetingabstracts.org/cgi/content/meeting_abstract/2009/2_Annual_Meeting/3676?maxtoshow=&hits=10&RESULTFORMAT=&fulltext=Antrodia&andorexactfulltext=and&searchid=1&FIRSTINDEX=0&sortspec=relevance&resourcetype=HWCIT, (20140620), XP002726800 [Y] 1-15 * Antroquinonol inhibits cancer cell growth, cancer cell migration and invasion and selectively reduces cell survival signaling in the highly invasive lung adenocarcinoma cells. On the basis of this finding it is proposed as an anti-cancer drug for NSCLC treatment. *
		[Y] - WATERHOUSE RIKKI N, "Determination of lipophilicity and its use as a predictor of blood-brain barrier penetration of molecular imaging agents.", MOLECULAR IMAGING AND BIOLOGY : MIB : THE OFFICIAL PUBLICATION OF THE ACADEMY OF MOLECULAR IMAGING 2003 NOV-DEC, (200311), vol. 5, no. 6, ISSN 1536-1632, pages 376 - 389, XP002730385 [Y] 1-15 * Predicting the ability of molecules to cross the blood brain barrier * DOI: http://dx.doi.org/10.1016/j.mibio.2003.09.014
		[Y] - RANGEL-ORDÓÑEZ LAURA ET AL, "Plasma levels and distribution of flavonoids in rat brain after single and repeated doses of standardized Ginkgo biloba extract EGb 761(R).", PLANTA MEDICA OCT 2010, (201010), vol. 76, no. 15, ISSN 1439-0221, pages 1683 - 1690, XP002730386 [Y] 1-15 * Flavonoids from extracts of Ginko Biloba pass the Blood Brain Barrier * DOI: http://dx.doi.org/10.1055/s-0030-1249962
	International search	[A]US2011123562 (CHIANG BEEN-HUANG [TW], et al);
		[A]US2011059123 (LIU SHENG-YUN [TW], et al);
		[A]US2011059122 (LIU SHENG-YUN [TW], et al);
		[A]US2011060059 (LIU SHENG-YUN [TW], et al);
		[A]US2011060058 (LIU SHENG-YUN [TW], et al);
		[A]US2011060057 (LIU SHENG-YUN [TW], et al);
		[A]US2011060056 (LIU SHENG-YUN [TW], et al);
		[A]US2011009494 (LIU SHENG-YUN [TW], et al);
		[A]US2011009495 (LIU SHENG-YUN [TW], et al);
		[A] - V. BHARATH KUMAR ET AL., "Antroquinonol inhibits NSCLC proliferation by alte ring PI3K/mTOR proteins and miRNA expression profiles.", MUTATION RESEARCH., (20110210), vol. 707, no. 1-2, pages 42 - 52, XP028134828 DOI: http://dx.doi.org/10.1016/j.mrfmmm.2010.12.009

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