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Extract from the Register of European Patents

EP About this file: EP2737064

EP2737064 - METHOD FOR SCREENING INDUCED PLURIPOTENT STEM CELLS [Right-click to bookmark this link]
StatusNo opposition filed within time limit
Status updated on  12.10.2018
Database last updated on 18.01.2025
FormerThe patent has been granted
Status updated on  03.11.2017
FormerGrant of patent is intended
Status updated on  25.06.2017
Most recent event   Tooltip17.07.2020Lapse of the patent in a contracting state
New state(s): AL
published on 19.08.2020  [2020/34]
Applicant(s)For all designated states
Kyoto University
36-1, Yoshida-honmachi Sakyo-ku
Kyoto-shi, Kyoto 606-8501 / JP
[2014/23]
Inventor(s)01 / YAMANAKA, Shinya
c/o Center for iPS Cell Research and Application
Kyoto University
53 Kawahara-cho
Shogoin, Sakyo-ku
Kyoto-shi Kyoto 606-8507 / JP
02 / TAKAHASHI, Kazutoshi
c/o Center for iPS Cell Research and Application
Kyoto University
53 Kawahara-cho
Shogoin, Sakyo-ku
Kyoto-shi Kyoto 606-8507 / JP
03 / KOYANAGI, Michiyo
c/o Center for iPS Cell Research and Application
Kyoto University
53 Kawahara-cho
Shogoin, Sakyo-ku
Kyoto-shi Kyoto 606-8507 / JP
04 / OHNUKI, Mari
c/o Center for iPS Cell Research and Application
Kyoto University
53 Kawahara-cho
Shogoin, Sakyo-ku
Kyoto-shi Kyoto 606-8507 / JP
 [2014/23]
Representative(s)D Young & Co LLP
3 Noble Street
London EC2V 7BQ / GB
[N/P]
Former [2017/49]D Young & Co LLP
120 Holborn
London EC1N 2DY / GB
Former [2014/23]Dempster, Robert Charles
D Young & Co LLP 120 Holborn
London EC1N 2DY / GB
Application number, filing date12818307.625.07.2012
[2017/49]
WO2012JP04747
Priority number, dateUS201161511156P25.07.2011         Original published format: US 201161511156 P
[2014/23]
Filing languageEN
Procedural languageEN
PublicationType: A1 Application with search report
No.:WO2013014929
Date:31.01.2013
Language:EN
[2013/05]
Type: A1 Application with search report 
No.:EP2737064
Date:04.06.2014
Language:EN
The application published by WIPO in one of the EPO official languages on 31.01.2013 takes the place of the publication of the European patent application.
[2014/23]
Type: B1 Patent specification 
No.:EP2737064
Date:06.12.2017
Language:EN
[2017/49]
Search report(s)International search report - published on:JP31.01.2013
(Supplementary) European search report - dispatched on:EP10.07.2015
ClassificationIPC:C12N15/09, C12N5/10, C12Q1/02, C12Q1/68, G01N33/50, G01N33/53
[2014/23]
CPC:
C12Q1/6881 (EP,US); C12Q1/6888 (KR,US); G01N33/5023 (EP,US);
G01N33/5073 (EP,US); C12Q2600/158 (EP,US)
Designated contracting statesAL,   AT,   BE,   BG,   CH,   CY,   CZ,   DE,   DK,   EE,   ES,   FI,   FR,   GB,   GR,   HR,   HU,   IE,   IS,   IT,   LI,   LT,   LU,   LV,   MC,   MK,   MT,   NL,   NO,   PL,   PT,   RO,   RS,   SE,   SI,   SK,   SM,   TR [2014/23]
Extension statesBANot yet paid
MENot yet paid
TitleGerman:VERFAHREN ZUM SCREENING INDUZIERTER PLURIPOTENTER STAMMZELLEN[2014/23]
English:METHOD FOR SCREENING INDUCED PLURIPOTENT STEM CELLS[2014/23]
French:PROCÉDÉ POUR LE CRIBLAGE DE CELLULES SOUCHES PLURIPOTENTES INDUITES[2014/23]
Entry into regional phase24.02.2014National basic fee paid 
24.02.2014Search fee paid 
24.02.2014Designation fee(s) paid 
24.02.2014Examination fee paid 
Examination procedure24.02.2014Examination requested  [2014/23]
08.01.2016Amendment by applicant (claims and/or description)
22.04.2016Despatch of a communication from the examining division (Time limit: M04)
08.08.2016Reply to a communication from the examining division
26.06.2017Communication of intention to grant the patent
26.10.2017Fee for grant paid
26.10.2017Fee for publishing/printing paid
26.10.2017Receipt of the translation of the claim(s)
Divisional application(s)EP17198984.1  / EP3305899
EP19182668.4  / EP3608423
The date of the Examining Division's first communication in respect of the earliest application for which a communication has been issued is  22.04.2016
Opposition(s)07.09.2018No opposition filed within time limit [2018/46]
Fees paidRenewal fee
16.07.2014Renewal fee patent year 03
16.07.2015Renewal fee patent year 04
18.07.2016Renewal fee patent year 05
17.07.2017Renewal fee patent year 06
Opt-out from the exclusive  Tooltip
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Patent Court
See the Register of the Unified Patent Court for opt-out data
Responsibility for the accuracy, completeness or quality of the data displayed under the link provided lies entirely with the Unified Patent Court.
Lapses during opposition  TooltipHU25.07.2012
AL06.12.2017
AT06.12.2017
CY06.12.2017
CZ06.12.2017
DK06.12.2017
EE06.12.2017
ES06.12.2017
FI06.12.2017
HR06.12.2017
IT06.12.2017
LT06.12.2017
LV06.12.2017
MC06.12.2017
MK06.12.2017
NL06.12.2017
PL06.12.2017
PT06.12.2017
RO06.12.2017
RS06.12.2017
SE06.12.2017
SI06.12.2017
SK06.12.2017
SM06.12.2017
TR06.12.2017
BG06.03.2018
NO06.03.2018
GR07.03.2018
IS06.04.2018
IE25.07.2018
LU25.07.2018
MT25.07.2018
BE31.07.2018
CH31.07.2018
LI31.07.2018
[2020/33]
Former [2020/32]HU25.07.2012
AT06.12.2017
CY06.12.2017
CZ06.12.2017
DK06.12.2017
EE06.12.2017
ES06.12.2017
FI06.12.2017
HR06.12.2017
IT06.12.2017
LT06.12.2017
LV06.12.2017
MC06.12.2017
MK06.12.2017
NL06.12.2017
PL06.12.2017
PT06.12.2017
RO06.12.2017
RS06.12.2017
SE06.12.2017
SI06.12.2017
SK06.12.2017
SM06.12.2017
TR06.12.2017
BG06.03.2018
NO06.03.2018
GR07.03.2018
IS06.04.2018
IE25.07.2018
LU25.07.2018
MT25.07.2018
BE31.07.2018
CH31.07.2018
LI31.07.2018
Former [2020/31]HU25.07.2012
AT06.12.2017
CY06.12.2017
CZ06.12.2017
DK06.12.2017
EE06.12.2017
ES06.12.2017
FI06.12.2017
HR06.12.2017
IT06.12.2017
LT06.12.2017
LV06.12.2017
MC06.12.2017
MK06.12.2017
NL06.12.2017
PL06.12.2017
PT06.12.2017
RO06.12.2017
RS06.12.2017
SE06.12.2017
SI06.12.2017
SK06.12.2017
SM06.12.2017
TR06.12.2017
BG06.03.2018
NO06.03.2018
GR07.03.2018
IE25.07.2018
LU25.07.2018
MT25.07.2018
BE31.07.2018
CH31.07.2018
LI31.07.2018
Former [2020/28]HU25.07.2012
AT06.12.2017
CZ06.12.2017
DK06.12.2017
EE06.12.2017
ES06.12.2017
FI06.12.2017
HR06.12.2017
IT06.12.2017
LT06.12.2017
LV06.12.2017
MC06.12.2017
NL06.12.2017
PL06.12.2017
PT06.12.2017
RO06.12.2017
RS06.12.2017
SE06.12.2017
SI06.12.2017
SK06.12.2017
SM06.12.2017
TR06.12.2017
BG06.03.2018
NO06.03.2018
GR07.03.2018
IE25.07.2018
LU25.07.2018
MT25.07.2018
BE31.07.2018
CH31.07.2018
LI31.07.2018
Former [2020/16]AT06.12.2017
CZ06.12.2017
DK06.12.2017
EE06.12.2017
ES06.12.2017
FI06.12.2017
HR06.12.2017
IT06.12.2017
LT06.12.2017
LV06.12.2017
MC06.12.2017
NL06.12.2017
PL06.12.2017
RO06.12.2017
RS06.12.2017
SE06.12.2017
SI06.12.2017
SK06.12.2017
SM06.12.2017
TR06.12.2017
BG06.03.2018
NO06.03.2018
GR07.03.2018
IE25.07.2018
LU25.07.2018
MT25.07.2018
BE31.07.2018
CH31.07.2018
LI31.07.2018
Former [2020/08]AT06.12.2017
CZ06.12.2017
DK06.12.2017
EE06.12.2017
ES06.12.2017
FI06.12.2017
HR06.12.2017
IT06.12.2017
LT06.12.2017
LV06.12.2017
MC06.12.2017
NL06.12.2017
PL06.12.2017
RO06.12.2017
RS06.12.2017
SE06.12.2017
SI06.12.2017
SK06.12.2017
SM06.12.2017
BG06.03.2018
NO06.03.2018
GR07.03.2018
IE25.07.2018
LU25.07.2018
MT25.07.2018
BE31.07.2018
CH31.07.2018
LI31.07.2018
Former [2019/24]AT06.12.2017
CZ06.12.2017
DK06.12.2017
EE06.12.2017
ES06.12.2017
FI06.12.2017
HR06.12.2017
IT06.12.2017
LT06.12.2017
LV06.12.2017
MC06.12.2017
NL06.12.2017
PL06.12.2017
RO06.12.2017
RS06.12.2017
SE06.12.2017
SI06.12.2017
SK06.12.2017
SM06.12.2017
BG06.03.2018
NO06.03.2018
GR07.03.2018
IE25.07.2018
LU25.07.2018
BE31.07.2018
CH31.07.2018
LI31.07.2018
Former [2019/21]AT06.12.2017
CZ06.12.2017
DK06.12.2017
EE06.12.2017
ES06.12.2017
FI06.12.2017
HR06.12.2017
IT06.12.2017
LT06.12.2017
LV06.12.2017
MC06.12.2017
NL06.12.2017
PL06.12.2017
RO06.12.2017
RS06.12.2017
SE06.12.2017
SI06.12.2017
SK06.12.2017
SM06.12.2017
BG06.03.2018
NO06.03.2018
GR07.03.2018
IE25.07.2018
LU25.07.2018
CH31.07.2018
LI31.07.2018
Former [2019/19]AT06.12.2017
CZ06.12.2017
DK06.12.2017
EE06.12.2017
ES06.12.2017
FI06.12.2017
HR06.12.2017
IT06.12.2017
LT06.12.2017
LV06.12.2017
MC06.12.2017
NL06.12.2017
PL06.12.2017
RO06.12.2017
RS06.12.2017
SE06.12.2017
SI06.12.2017
SK06.12.2017
SM06.12.2017
BG06.03.2018
NO06.03.2018
GR07.03.2018
IE25.07.2018
LU25.07.2018
Former [2019/17]AT06.12.2017
CZ06.12.2017
DK06.12.2017
EE06.12.2017
ES06.12.2017
FI06.12.2017
HR06.12.2017
IT06.12.2017
LT06.12.2017
LV06.12.2017
MC06.12.2017
NL06.12.2017
PL06.12.2017
RO06.12.2017
RS06.12.2017
SE06.12.2017
SI06.12.2017
SK06.12.2017
SM06.12.2017
BG06.03.2018
NO06.03.2018
GR07.03.2018
LU25.07.2018
Former [2019/15]AT06.12.2017
CZ06.12.2017
DK06.12.2017
EE06.12.2017
ES06.12.2017
FI06.12.2017
HR06.12.2017
IT06.12.2017
LT06.12.2017
LV06.12.2017
MC06.12.2017
NL06.12.2017
PL06.12.2017
RO06.12.2017
RS06.12.2017
SE06.12.2017
SI06.12.2017
SK06.12.2017
SM06.12.2017
BG06.03.2018
NO06.03.2018
GR07.03.2018
Former [2018/52]AT06.12.2017
CZ06.12.2017
DK06.12.2017
EE06.12.2017
ES06.12.2017
FI06.12.2017
HR06.12.2017
IT06.12.2017
LT06.12.2017
LV06.12.2017
NL06.12.2017
PL06.12.2017
RO06.12.2017
RS06.12.2017
SE06.12.2017
SI06.12.2017
SK06.12.2017
SM06.12.2017
BG06.03.2018
NO06.03.2018
GR07.03.2018
Former [2018/51]AT06.12.2017
CZ06.12.2017
DK06.12.2017
EE06.12.2017
ES06.12.2017
FI06.12.2017
HR06.12.2017
IT06.12.2017
LT06.12.2017
LV06.12.2017
NL06.12.2017
PL06.12.2017
RO06.12.2017
RS06.12.2017
SE06.12.2017
SK06.12.2017
SM06.12.2017
BG06.03.2018
NO06.03.2018
GR07.03.2018
Former [2018/40]AT06.12.2017
CZ06.12.2017
EE06.12.2017
ES06.12.2017
FI06.12.2017
HR06.12.2017
IT06.12.2017
LT06.12.2017
LV06.12.2017
NL06.12.2017
PL06.12.2017
RO06.12.2017
RS06.12.2017
SE06.12.2017
SK06.12.2017
SM06.12.2017
BG06.03.2018
NO06.03.2018
GR07.03.2018
Former [2018/39]AT06.12.2017
CZ06.12.2017
EE06.12.2017
ES06.12.2017
FI06.12.2017
HR06.12.2017
IT06.12.2017
LT06.12.2017
LV06.12.2017
NL06.12.2017
PL06.12.2017
RS06.12.2017
SE06.12.2017
SK06.12.2017
SM06.12.2017
BG06.03.2018
NO06.03.2018
GR07.03.2018
Former [2018/38]AT06.12.2017
CZ06.12.2017
EE06.12.2017
ES06.12.2017
FI06.12.2017
HR06.12.2017
LT06.12.2017
LV06.12.2017
NL06.12.2017
PL06.12.2017
RS06.12.2017
SE06.12.2017
SK06.12.2017
SM06.12.2017
BG06.03.2018
NO06.03.2018
GR07.03.2018
Former [2018/37]CZ06.12.2017
EE06.12.2017
ES06.12.2017
FI06.12.2017
HR06.12.2017
LT06.12.2017
LV06.12.2017
NL06.12.2017
PL06.12.2017
RS06.12.2017
SE06.12.2017
SK06.12.2017
SM06.12.2017
BG06.03.2018
NO06.03.2018
GR07.03.2018
Former [2018/34]ES06.12.2017
FI06.12.2017
HR06.12.2017
LT06.12.2017
LV06.12.2017
NL06.12.2017
RS06.12.2017
SE06.12.2017
BG06.03.2018
NO06.03.2018
GR07.03.2018
Former [2018/24]ES06.12.2017
FI06.12.2017
HR06.12.2017
LT06.12.2017
LV06.12.2017
RS06.12.2017
SE06.12.2017
BG06.03.2018
NO06.03.2018
GR07.03.2018
Former [2018/23]ES06.12.2017
FI06.12.2017
HR06.12.2017
LT06.12.2017
RS06.12.2017
SE06.12.2017
NO06.03.2018
GR07.03.2018
Former [2018/22]ES06.12.2017
FI06.12.2017
LT06.12.2017
NO06.03.2018
Documents cited:Search[X]RU2340896  (NEGOSUDARSTVENNOE NI SKOE UCHR [RU]) [X] 6,7,9 * the whole document, in particular abstract *;
 [A]JP2010172225  (NATL INST RADIOLOGICAL SCIENCE) [A] 1-3,5-9 * the whole document, in particular claims 1, 3, 11 *;
 [A]WO2010137348  (UNIV KEIO [JP], et al) [A] 1-3,5-9 * the whole document, in particular abstract; paragraphs [0027], [0035]; claims 1, 3, 9, 11 *;
 [A]  - HYESOO KIM ET AL, "miR-371-3 Expression Predicts Neural Differentiation Propensity in Human Pluripotent Stem Cells", CELL STEM CELL, ELSEVIER, CELL PRESS, AMSTERDAM, NL, vol. 8, no. 6, doi:10.1016/J.STEM.2011.04.002, ISSN 1934-5909, (20110316), pages 695 - 706, (20110415), XP028386711 [A] 1-3,5-9 * the whole document, in particular title; abstract; paragraph spanning pages 695 and 696; page 704, column 2, concluding paragraph *

DOI:   http://dx.doi.org/10.1016/j.stem.2011.04.002
 [A]  - CHRISTOPH BOCK ET AL, "Reference Maps of Human ES and iPS Cell Variation Enable High-Throughput Characterization of Pluripotent Cell Lines", CELL, CELL PRESS, US, vol. 144, no. 3, doi:10.1016/J.CELL.2010.12.032, ISSN 0092-8674, (20101217), pages 439 - 452, (20110104), XP028203109 [A] 1-3,5-9 * the whole document, in particular abstract *

DOI:   http://dx.doi.org/10.1016/j.cell.2010.12.032
 [X]  - David Weiss, "The Agilent Gene Expression Platform: LINC-ing To The Future with Increased Density", (20101118), pages 1 - 16, URL: http://www.chem.agilent.com/Library/slidepresentation/Public/The%20Agilent%20Gene%20Expression%20Platform_111810.pdf, (20150304), XP055173756 [X] 6,7,9 * the whole document, in particular last page: "SurePrint G3 Human GE 8x60K kit" *
 [I]  - KOWALSKI P E ET AL, "Intergenic Splicing between a HERV-H Endogenous Retrovirus and Two Adjacent Human Genes", GENOMICS, ACADEMIC PRESS, SAN DIEGO, US, (19990501), vol. 57, no. 3, doi:10.1006/GENO.1999.5787, ISSN 0888-7543, pages 371 - 379, XP004444907 [I] 8 * the whole document, in particular abstract *

DOI:   http://dx.doi.org/10.1006/geno.1999.5787
 [T]  - M. KOYANAGI-AOI ET AL, "Differentiation-defective phenotypes revealed by large-scale analyses of human pluripotent stem cells", PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES, (20131120), vol. 110, no. 51, doi:10.1073/pnas.1319061110, ISSN 0027-8424, pages 20569 - 20574, XP055173687 [T] * the whole document *

DOI:   http://dx.doi.org/10.1073/pnas.1319061110
International search[X]WO2011087154  (UNIV KYOTO [JP], et al);
by applicantWO2007069666
 WO2008118820
 WO2010013845
 JP2010172225
 WO2010131747
 WO2010137348
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