EP2749572 - NOVEL ANTI-DDR1 ANTIBODY HAVING ANTI-TUMOR ACTIVITY [Right-click to bookmark this link] | Status | The application is deemed to be withdrawn Status updated on 09.10.2020 Database last updated on 31.08.2024 | |
Former | Grant of patent is intended Status updated on 08.12.2019 | ||
Former | Examination is in progress Status updated on 11.11.2016 | Most recent event Tooltip | 09.10.2020 | Application deemed to be withdrawn | published on 11.11.2020 [2020/46] | Applicant(s) | For all designated states Chugai Seiyaku Kabushiki Kaisha 5-1, Ukima 5-chome Kita-ku Tokyo 115-8543 / JP | [2014/27] | Inventor(s) | 01 /
ONO, Mei c/o CHUGAI SEIYAKU KABUSHIKI KAISHA 200 Kajiwara Kamakura-shi Kanagawa 247-8530 / JP | 02 /
SANO, Yuji c/o CHUGAI SEIYAKU KABUSHIKI KAISHA 200 Kajiwara Kamakura-shi Kanagawa 247-8530 / JP | 03 /
SUZUKI, Tsukasa c/o CHUGAI SEIYAKU KABUSHIKI KAISHA 135 Komakado 1-chome Gotemba-shi Shizuoka 412-8513 / JP | [2014/27] | Representative(s) | Bösl, Raphael Konrad Patentanwälte Isenbruck Bösl Hörschler PartG mbB Eastsite One Seckenheimer Landstraße 4 68163 Mannheim / DE | [N/P] |
Former [2014/27] | Bösl, Raphael Konrad Isenbruck Bösl Hörschler LLP Patentanwälte Prinzregentenstrasse 68 81675 München / DE | Application number, filing date | 12826213.6 | 23.08.2012 | WO2012JP71332 | Priority number, date | JP20110181683 | 23.08.2011 Original published format: JP 2011181683 | [2014/27] | Filing language | JA | Procedural language | EN | Publication | Type: | A1 Application with search report | No.: | WO2013027802 | Date: | 28.02.2013 | Language: | JA | [2013/09] | Type: | A1 Application with search report | No.: | EP2749572 | Date: | 02.07.2014 | Language: | EN | [2014/27] | Search report(s) | International search report - published on: | JP | 28.02.2013 | (Supplementary) European search report - dispatched on: | EP | 26.02.2015 | Classification | IPC: | C07K16/30, A61K39/395, A61P35/00, C12N1/15, C12N1/19, C12N1/21, C12N5/10, C12N15/09, C12P21/08, C07K16/28, A61K47/18, C07K16/40, A61K39/00 | [2018/03] | CPC: |
C07K16/2851 (EP,US);
C07K16/40 (US);
A61K39/3955 (US);
A61P35/00 (EP);
C07K16/3023 (EP,US);
A61K2039/505 (EP,US);
|
Former IPC [2015/14] | C07K16/30, A61K39/395, A61P35/00, C12N1/15, C12N1/19, C12N1/21, C12N5/10, C12N15/09, C12P21/08, C07K16/28, A61K47/18, C07K16/40, A61K47/48, A61K39/00 | ||
Former IPC [2014/27] | C07K16/30, A61K39/395, A61P35/00, C12N1/15, C12N1/19, C12N1/21, C12N5/10, C12N15/09, C12P21/08 | Designated contracting states | AL, AT, BE, BG, CH, CY, CZ, DE, DK, EE, ES, FI, FR, GB, GR, HR, HU, IE, IS, IT, LI, LT, LU, LV, MC, MK, MT, NL, NO, PL, PT, RO, RS, SE, SI, SK, SM, TR [2014/27] | Title | German: | NEUER ANTI-DDR1-ANTIKÖRPER MIT ANTITUMORAKTIVITÄT | [2014/27] | English: | NOVEL ANTI-DDR1 ANTIBODY HAVING ANTI-TUMOR ACTIVITY | [2014/27] | French: | NOUVEL ANTICORPS ANTI-DDR1 AYANT UNE ACTIVITÉ ANTI-TUMORALE | [2014/27] | Biological material | This application mentions deposited biological material, check the file for details | Entry into regional phase | 21.03.2014 | Translation filed | 21.03.2014 | National basic fee paid | 21.03.2014 | Search fee paid | 21.03.2014 | Designation fee(s) paid | 21.03.2014 | Examination fee paid | Examination procedure | 21.03.2014 | Examination requested [2014/27] | 22.09.2015 | Amendment by applicant (claims and/or description) | 10.11.2016 | Despatch of a communication from the examining division (Time limit: M04) | 06.02.2017 | Reply to a communication from the examining division | 06.07.2017 | Despatch of a communication from the examining division (Time limit: M04) | 25.09.2017 | Reply to a communication from the examining division | 21.03.2018 | Despatch of a communication from the examining division (Time limit: M04) | 26.07.2018 | Reply to a communication from the examining division | 04.10.2018 | Despatch of a communication from the examining division (Time limit: M04) | 14.11.2018 | Reply to a communication from the examining division | 03.04.2019 | Despatch of a communication from the examining division (Time limit: M02) | 17.05.2019 | Reply to a communication from the examining division | 09.12.2019 | Communication of intention to grant the patent | 03.06.2020 | Application deemed to be withdrawn, date of legal effect [2020/46] | 25.06.2020 | Despatch of communication that the application is deemed to be withdrawn, reason: fee for grant / fee for printing not paid in time [2020/46] | Divisional application(s) | The date of the Examining Division's first communication in respect of the earliest application for which a communication has been issued is 10.11.2016 | Fees paid | Renewal fee | 25.08.2014 | Renewal fee patent year 03 | 20.08.2015 | Renewal fee patent year 04 | 22.08.2016 | Renewal fee patent year 05 | 22.08.2017 | Renewal fee patent year 06 | 28.08.2018 | Renewal fee patent year 07 | 26.08.2019 | Renewal fee patent year 08 | Penalty fee | Additional fee for renewal fee | 31.08.2020 | 09   M06   Not yet paid |
Opt-out from the exclusive Tooltip competence of the Unified Patent Court | See the Register of the Unified Patent Court for opt-out data | ||
Responsibility for the accuracy, completeness or quality of the data displayed under the link provided lies entirely with the Unified Patent Court. | Documents cited: | Search | [XDI]WO2010019702 (ONCOMED PHARM INC [US], et al) [XD] 1,4-14,16 * See § 0072, claims 1-66 *[I] 2,3,15 | International search | [X]JP2005521420 (AGY THERAPEUTICS, INC.); | [Y]WO2006098465 (TAKEDA PHARMACEUTICAL [JP], et al); | [Y]WO2010019702 (ONCOMED PHARM INC [US], et al); | [Y] - ABDULHUSSEIN R. ET AL., "Identification of Disulfide-linked Dimers of the Receptor Tyrosine Kinase DDR1", THE JOURNAL OF BIOLOGICAL CHEMISTRY, (2008), vol. 283, no. 18, pages 12026 - 12033, XP055145958 DOI: http://dx.doi.org/10.1074/jbc.M704592200 | [Y] - GUERROT D. ET AL., "Discoidin Domain Receptor 1 Is a Major Mediator of Inflammation and Fibrosis in Obstructive Nephropathy", THE AMERICAN JOURNAL OF PATHOLOGY, (201107), vol. 179, no. 1, pages 83 - 91, XP055145961 DOI: http://dx.doi.org/10.1016/j.ajpath.2011.03.023 | [XP] - CARAFOLI F. ET AL., "Structure of the Discoidin Domain Receptor 1 Extracellular Region Bound to an Inhibitory Fab Fragment Reveals Features Important for Signaling", STRUCTURE, (201204), vol. 20, pages 688 - 697, XP055090582 DOI: http://dx.doi.org/10.1016/j.str.2012.02.011 | by applicant | EP0239400 | JPH0159878B | EP0404097 | US5057313 | WO9201047 | WO9203918 | US5156840 | WO9220791 | WO9306213 | WO9311236 | WO9311161 | WO9312227 | WO9319172 | WO9402602 | WO9411523 | WO9425585 | WO9501438 | WO9502187 | WO9515388 | WO9602576 | WO9634096 | WO9633735 | WO2006098465 | WO2010001972 | WO2010019702 | - JOHNSON J.D. ET AL., PROC.NATL.ACAD.SCI.USA, (1993), vol. 90, pages 5677 - 81 | - SHINTANI Y ET AL., J. CELL BIOL., (2008), vol. 180, pages 1277 - 89 | - CURAT C.A. ET AL., J.BIOL.CHEM., (2001), vol. 276, pages 45952 - 58 | - ABDULHUSSEIN R. ET AL., J.BIOL.CHEM., (2008), vol. 283, pages 12026 - 12033 | - FRANCO C. ET AL., CIRC.RES., (2009), vol. 105, pages 1141 - 8 | - SHIMADA K. ET AL., CANCER SCI., (2008), vol. 99, pages 39 - 45 | - KIM H.G. ET AL., J.BIOL.CHEM., (2011), vol. 286, pages 17672 - 81 | - YANG S.H. ET AL., ONCOL.REP, (2010), vol. 24, pages 311 - 9 | - RAM R. ET AL., J.NEUROONCO1., (2006), vol. 76, pages 239 - 48 | - KIMMAN M.L. ET AL., BMC CANCER, (2007), vol. 7, pages 1 - 20 | - COLAS E. ET AL., INT.J.CANCER, (2011), page 129 | - HEINZELMANN-SCHWARZ VA. ET AL., CLIN.CANCER RES., (2004), vol. 10, pages 4427 - 36 | - RIKOVA K. ET AL., CELL, (2007), vol. 131, pages 1190 - 203 | - GU T.L. ET AL., PLOS ONE, (2011), vol. 6, page E15640 | - YAMANAKA R. ET AL., ONCOGENE, (2006), vol. 25, pages 5994 - 6002 | - HIDALGO-CARCEDO C. ET AL., NAT.CELL BIOL., (2011), vol. 13, pages 49 - 58 | - YANG, S. H. ET AL., ONCOL. REP., (2010), vol. 24, pages 311 - 319 | - VOGEL, W. ET AL., MOL. CELL, (1997), vol. 1, pages 13 - 23 | - L'HOTE, C. G M. ET AL., FASEB J, (2002), vol. 16, pages 234 - 6 | - RIKOVA, K. ET AL., CELL, (2007), vol. 131, pages 1190 - 203 | - SHINTANI, Y ET AL., J. CELL. BIOL., (2008), vol. 180, pages 1277 - 1289 | - GUERROT, D. ET AL., AM. J. PATHOL., (2011), vol. 179, pages 83 - 91 | - POETZ, O. ET AL., PROTEOMICS, (2005), vol. 5, pages 2402 - 11 | - VYAS, N. K. ET AL., BIOCHEMISTRY, (2004), vol. 41, pages 13575 - 86 | - CUNNINGHAM, B. C.; WELLS, J. A., SCIENCE, (1989), vol. 244, pages 1081 - 5 | - SMITH, G. P.; PETRENKO, V A., CHEM. REV., (1997), vol. 97, pages 391 - 410 | - HASHIMOTO-GOTOH, T. ET AL., GENE, (1995), vol. 152, pages 271 - 275 | - ZOLLER, M. J.; SMITH, M., METHODS ENZYMOL., (1983), vol. 100, pages 468 - 500 | - KRAMER, W. ET AL., NUCLEIC ACIDS RES., (1987), vol. 12, pages 9441 - 9456 | - KRAMER W; FRITZ H. J., METHODS ENZYMOL, (1987), vol. 154, pages 350 - 367 | - KUNKEL, T. A., PROC. NATL. ACAD. SCI. USA, (1985), vol. 82, pages 488 - 492 | - MARK, D. F. ET AL., PROC. NATL. ACAD. SCI. USA, (1984), vol. 81, pages 5662 - 5666 | - WANG, A. ET AL., SCIENCE, (1984), vol. 224, pages 1431 - 1433 | - SAMBROOK J. ET AL., Molecular Cloning, COLD SPRING HARBOR LAB.PRESS, (1989), pages 9.47 - 9.58 | - J.IMMUNOL., (1979), vol. 123, pages 1548 - 1550 | - CURRENT TOPICS IN MICROBIOLOGY AND IMMUNOLOGY, (1978), vol. 81, pages 1 - 7 | - KOHLER G; MILSTEIN C., EUR.J.IMMUNOL., (1976), vol. 6, pages 511 - 519 | - MARGULIES D.H. ET AL., CELL, (1976), vol. 8, pages 405 - 415 | - SHULMAN M. ET AL., NATURE, (1978), vol. 276, pages 269 - 270 | - DE ST.GROTH S.F. ET AL., J.IMMUNOL.METHODS, (1980), vol. 35, pages 1 - 21 | - TROWBRIDGE I.S.J., EXP.MED., (1978), vol. 148, pages 313 - 323 | - GALFRE G ET AL., NATURE, (1979), vol. 277, pages 131 - 133 | - KOHLER G; MILSTEIN C., METHODS ENZYMOL., (1981), vol. 73, pages 3 - 46 | - VANDAMME, A.M. ET AL., EUR. J. BIOCHEM., (1990), vol. 192, pages 767 - 775 | - CHIRGWIN, J.M. ET AL., BIOCHEMISTRY, (1979), vol. 18, pages 5294 - 5299 | - CHOMCZYNSKI, P. ET AL., ANAL. BIOCHEM., (1987), vol. 162, pages 156 - 159 | - FROHMAN, M.A. ET AL., PROC. NATL ACAD. SCI. U. S. A., (1988), vol. 85, pages 8998 - 9002 | - BELYAVSKY, A. ET AL., NUCLEIC ACIDS RES., (1989), vol. 17, pages 2919 - 2932 | - J. MOL. BIOL., (1991), vol. 222, pages 581 - 597 | - NATURE, (1979), vol. 277, page 108 | - MIZUSHIMA ET AL., NUCLEIC ACIDS RES., (1990), vol. 18, page 5322 | - NATURE, (1989), vol. 341, pages 544 - 546 | - FASEB J, (1992), vol. 6, pages 2422 - 2427 | - BETTER ET AL., SCIENCE, (1988), vol. 240, pages 1041 - 1043 | - LEI, S. P ET AL., J. BACTERIOL., (1987), vol. 169, page 4379 | - EBERT, K. M. ET AL., BIO/TECHNOLOGY, (1994), vol. 12, pages 699 - 702 | - SUSUMU ET AL., NATURE, (1985), vol. 315, pages 592 - 4 | - MA ET AL., EUR. J. IMMUNOL., (1994), vol. 24, pages 131 - 8 | - SATO, K. ET AL., CANCER RES., (1993), vol. 53, pages 851 - 856 | - CO M.S. ET AL., J.IMMUNOL., (1994), vol. 152, pages 2968 - 2976 | - BETTER M.; HORWITZ A.H., METHODS IN ENZYMOLOGY, (1989), vol. 178, pages 476 - 496 | - PLUCKTHUN A.; SKERRA A., METHODS IN ENZYMOLOGY, (1989), vol. 178, pages 497 - 515 | - LAMOYI E., METHODS IN ENZYMOLOGY, (1986), vol. 121, pages 652 - 663 | - ROUSSEAUX J. ET AL., METHODS IN ENZYMOLOGY, (1986), vol. 121, pages 663 - 669 | - BIRD R.E.; WALKER B.W., TRENDS BIOTECHNOL., (1991), vol. 9, pages 132 - 137 | - HUSTON, J. S. ET AL., PROC. NATL ACAD. SCI. U. S. A., (1988), vol. 85, pages 5879 - 5883 | - HOLLIGER, P. ET AL., PROC. NATL. ACAD. SCI. USA, (1993), vol. 90, pages 6444 - 6448 | - HUDSON, P. J.; KORTT, A. A., J. IMMUNOL. METHODS, (1999), vol. 231, pages 177 - 189 | - PROTEIN ENGINEERING, (1996), vol. 9, pages 299 - 305 | - MOL. CELL. BIOL., (1988), vol. 8, pages 466 - 472 | - Remington's Pharmaceutical Science, MARK PUBLISHING COMPANY | - PACE C.N. ET AL., PROTEIN SCI., (1995), vol. 4, pages 2411 - 2423 | - LARRICK, J. W. ET AL., BIOCHEM. BIOPHYS. RES. COMMUN, (1989), vol. 160, pages 1250 - 1256 | - JONES, S. T.; BENDIG, M. M., BIOTECHNOLOGY, (1991), vol. 9, page 579 |