blank Quick help
blank Maintenance news

Scheduled maintenance

Regular maintenance outages:
between 05.00 and 05.15 hrs CET (Monday to Sunday).

Other outages
Availability

2022.02.11

More...
blank News flashes

News Flashes

New version of the European Patent Register – SPC proceedings information in the Unitary Patent Register.

2024-07-24

More...
blank Related links

Release notes
European Patent Register Assistant
European Patent Register Resource Book
European Patent Register – pocket guide
FAQ - European Patent Register
Federated Register (Flyer)
Global Dossier (Flyer)
Register events
Deep link coverage
Federated Register content
The Patent Information Tour
Fair use charter

Extract from the Register of European Patents

EP About this file: EP2764082

EP2764082 - SRM/MRM ASSAY FOR THE EPHRIN TYPE-A RECEPTOR 2 PROTEIN [Right-click to bookmark this link]
StatusNo opposition filed within time limit
Status updated on  29.03.2019
Database last updated on 18.11.2024
FormerThe patent has been granted
Status updated on  20.04.2018
FormerGrant of patent is intended
Status updated on  04.12.2017
FormerExamination is in progress
Status updated on  17.11.2017
FormerGrant of patent is intended
Status updated on  27.06.2017
FormerExamination is in progress
Status updated on  02.12.2016
Most recent event   Tooltip10.07.2020Lapse of the patent in a contracting state
New state(s): IS		published on 12.08.2020  [2020/33]
Applicant(s)For all designated states
Expression Pathology, Inc.
9600 Medical Center Drive, Suite 300
Rockville, MD 20850 / US
[2018/21]
Former [2016/03]For all designated states
Expression Pathology, Inc.
9600 Medical Center Drive Suite 300
Rockville MD 20850 / US
Former [2014/33]For all designated states
Expression Pathology, Inc.
9620 Medical Center Drive
Suite 100
Rockville, MD 20850 / US
Inventor(s)01 / KRIZMAN, David, B.
24305 Welsh Road
Gaithersburg, MD 20882 / US
02 / HEMBROUGH, Todd
24336 Newberry Road
Gaithersburg, MD 20882 / US
03 / THYPARAMBIL, Sheeno
3730 Singleton Terrace
Frederick, MD 21704 / US
04 / LIAO, Wei-Liao
1112 Shannon Place
Herndon, VA 20170 / US
 [2014/33]
Representative(s)Bohmann, Armin K.
Bohmann
Anwaltssozietät
Nymphenburger Straße 1
80335 München / DE
[2018/21]
Former [2014/33]Bohmann, Armin K.
bohmann Anwaltssozietät Nymphenburger Strasse 1
80335 München / DE
Application number, filing date12838494.804.10.2012
[2018/21]
WO2012US58815
Priority number, dateUS201161543106P04.10.2011         Original published format: US 201161543106 P
[2014/33]
Filing languageEN
Procedural languageEN
PublicationType: A1 Application with search report
No.:WO2013052710
Date:11.04.2013
Language:EN
[2013/15]
Type: A1 Application with search report 
No.:EP2764082
Date:13.08.2014
Language:EN
The application published by WIPO in one of the EPO official languages on 11.04.2013 takes the place of the publication of the European patent application.
[2014/33]
Type: B1 Patent specification 
No.:EP2764082
Date:23.05.2018
Language:EN
[2018/21]
Search report(s)International search report - published on:US11.04.2013
(Supplementary) European search report - dispatched on:EP13.04.2015
ClassificationIPC:G01N33/574, G01N33/68
[2017/28]
CPC:
G01N33/57492 (EP,US); C12Q1/485 (US); A61P35/00 (EP);
G01N2560/00 (US); G01N2800/56 (EP,US)
Former IPC [2015/20]C12M1/34, G01N33/68
Former IPC [2014/33]C12M1/34
Designated contracting statesAL,   AT,   BE,   BG,   CH,   CY,   CZ,   DE,   DK,   EE,   ES,   FI,   FR,   GB,   GR,   HR,   HU,   IE,   IS,   IT,   LI,   LT,   LU,   LV,   MC,   MK,   MT,   NL,   NO,   PL,   PT,   RO,   RS,   SE,   SI,   SK,   SM,   TR [2014/33]
Extension statesBANot yet paid
MENot yet paid
TitleGerman:SRM/MRM-TEST FÜR DAS EPHRIN-TYP-A-REZEPTOR-2-PROTEIN[2014/33]
English:SRM/MRM ASSAY FOR THE EPHRIN TYPE-A RECEPTOR 2 PROTEIN[2014/33]
French:DOSAGE SRM/MRM DE LA PROTÉINE RÉCEPTEUR 2 DE L'ÉPHRINE DE TYPE A[2014/33]
Entry into regional phase02.05.2014National basic fee paid 
02.05.2014Search fee paid 
02.05.2014Designation fee(s) paid 
02.05.2014Examination fee paid 
Examination procedure02.05.2014Amendment by applicant (claims and/or description)
02.05.2014Examination requested  [2014/33]
22.12.2015Despatch of communication that the application is deemed to be withdrawn, reason: reply to the Extended European Search Report/Written Opinion of the International Searching Authority/International Preliminary Examination Report/Supplementary international search report not received in time
02.12.2016Despatch of a communication from the examining division (Time limit: M04)
12.04.2017Reply to a communication from the examining division
28.06.2017Communication of intention to grant the patent
08.11.2017Disapproval of the communication of intention to grant the patent by the applicant or resumption of examination proceedings by the EPO
05.12.2017Communication of intention to grant the patent
09.04.2018Fee for grant paid
09.04.2018Fee for publishing/printing paid
09.04.2018Receipt of the translation of the claim(s)
Divisional application(s)The date of the Examining Division's first communication in respect of the earliest application for which a communication has been issued is  02.12.2016
Opposition(s)26.02.2019No opposition filed within time limit [2019/18]
Request for further processing for:The application is deemed to be withdrawn due to failure to reply to the Extended European Search Report/Written Opinion of the International Searching Authority/International Preliminary Examination Report/Supplementary international search report/Supplementary European search report
01.03.2016Request for further processing filed
01.03.2016Full payment received (date of receipt of payment)
Request granted
16.03.2016Decision despatched
Fees paidRenewal fee
14.10.2014Renewal fee patent year 03
12.10.2015Renewal fee patent year 04
21.10.2016Renewal fee patent year 05
25.10.2017Renewal fee patent year 06
Opt-out from the exclusive  Tooltip
competence of the Unified
Patent Court		 See the Register of the Unified Patent Court for opt-out data
Responsibility for the accuracy, completeness or quality of the data displayed under the link provided lies entirely with the Unified Patent Court.
Lapses during opposition  TooltipHU04.10.2012
AL23.05.2018
AT23.05.2018
CY23.05.2018
CZ23.05.2018
DK23.05.2018
EE23.05.2018
FI23.05.2018
HR23.05.2018
IT23.05.2018
LT23.05.2018
LV23.05.2018
MC23.05.2018
MK23.05.2018
NL23.05.2018
PL23.05.2018
PT23.05.2018
RO23.05.2018
RS23.05.2018
SE23.05.2018
SI23.05.2018
SK23.05.2018
SM23.05.2018
TR23.05.2018
BG23.08.2018
NO23.08.2018
GR24.08.2018
IS23.09.2018
LU04.10.2018
MT04.10.2018
BE31.10.2018
[2020/32]
Former [2020/31]HU04.10.2012
AL23.05.2018
AT23.05.2018
CY23.05.2018
CZ23.05.2018
DK23.05.2018
EE23.05.2018
FI23.05.2018
HR23.05.2018
IT23.05.2018
LT23.05.2018
LV23.05.2018
MC23.05.2018
MK23.05.2018
NL23.05.2018
PL23.05.2018
PT23.05.2018
RO23.05.2018
RS23.05.2018
SE23.05.2018
SI23.05.2018
SK23.05.2018
SM23.05.2018
TR23.05.2018
BG23.08.2018
NO23.08.2018
GR24.08.2018
LU04.10.2018
MT04.10.2018
BE31.10.2018
Former [2020/30]HU04.10.2012
AL23.05.2018
AT23.05.2018
CZ23.05.2018
DK23.05.2018
EE23.05.2018
FI23.05.2018
HR23.05.2018
IT23.05.2018
LT23.05.2018
LV23.05.2018
MC23.05.2018
NL23.05.2018
PL23.05.2018
PT23.05.2018
RO23.05.2018
RS23.05.2018
SE23.05.2018
SI23.05.2018
SK23.05.2018
SM23.05.2018
TR23.05.2018
BG23.08.2018
NO23.08.2018
GR24.08.2018
LU04.10.2018
MT04.10.2018
BE31.10.2018
Former [2020/28]AL23.05.2018
AT23.05.2018
CZ23.05.2018
DK23.05.2018
EE23.05.2018
FI23.05.2018
HR23.05.2018
IT23.05.2018
LT23.05.2018
LV23.05.2018
MC23.05.2018
NL23.05.2018
PL23.05.2018
PT23.05.2018
RO23.05.2018
RS23.05.2018
SE23.05.2018
SI23.05.2018
SK23.05.2018
SM23.05.2018
TR23.05.2018
BG23.08.2018
NO23.08.2018
GR24.08.2018
LU04.10.2018
MT04.10.2018
BE31.10.2018
Former [2020/16]AL23.05.2018
AT23.05.2018
CZ23.05.2018
DK23.05.2018
EE23.05.2018
FI23.05.2018
HR23.05.2018
IT23.05.2018
LT23.05.2018
LV23.05.2018
MC23.05.2018
NL23.05.2018
PL23.05.2018
RO23.05.2018
RS23.05.2018
SE23.05.2018
SI23.05.2018
SK23.05.2018
SM23.05.2018
TR23.05.2018
BG23.08.2018
NO23.08.2018
GR24.08.2018
LU04.10.2018
MT04.10.2018
BE31.10.2018
Former [2020/08]AL23.05.2018
AT23.05.2018
CZ23.05.2018
DK23.05.2018
EE23.05.2018
FI23.05.2018
HR23.05.2018
IT23.05.2018
LT23.05.2018
LV23.05.2018
MC23.05.2018
NL23.05.2018
PL23.05.2018
RO23.05.2018
RS23.05.2018
SE23.05.2018
SI23.05.2018
SK23.05.2018
SM23.05.2018
BG23.08.2018
NO23.08.2018
GR24.08.2018
LU04.10.2018
MT04.10.2018
BE31.10.2018
Former [2019/51]AL23.05.2018
AT23.05.2018
CZ23.05.2018
DK23.05.2018
EE23.05.2018
FI23.05.2018
HR23.05.2018
IT23.05.2018
LT23.05.2018
LV23.05.2018
MC23.05.2018
NL23.05.2018
PL23.05.2018
RO23.05.2018
RS23.05.2018
SE23.05.2018
SI23.05.2018
SK23.05.2018
SM23.05.2018
BG23.08.2018
NO23.08.2018
GR24.08.2018
LU04.10.2018
BE31.10.2018
Former [2019/38]AT23.05.2018
CZ23.05.2018
DK23.05.2018
EE23.05.2018
FI23.05.2018
HR23.05.2018
IT23.05.2018
LT23.05.2018
LV23.05.2018
MC23.05.2018
NL23.05.2018
PL23.05.2018
RO23.05.2018
RS23.05.2018
SE23.05.2018
SI23.05.2018
SK23.05.2018
SM23.05.2018
BG23.08.2018
NO23.08.2018
GR24.08.2018
LU04.10.2018
BE31.10.2018
Former [2019/30]AT23.05.2018
CZ23.05.2018
DK23.05.2018
EE23.05.2018
FI23.05.2018
HR23.05.2018
IT23.05.2018
LT23.05.2018
LV23.05.2018
MC23.05.2018
NL23.05.2018
PL23.05.2018
RO23.05.2018
RS23.05.2018
SE23.05.2018
SI23.05.2018
SK23.05.2018
SM23.05.2018
BG23.08.2018
NO23.08.2018
GR24.08.2018
LU04.10.2018
Former [2019/28]AT23.05.2018
CZ23.05.2018
DK23.05.2018
EE23.05.2018
FI23.05.2018
HR23.05.2018
IT23.05.2018
LT23.05.2018
LV23.05.2018
MC23.05.2018
NL23.05.2018
PL23.05.2018
RO23.05.2018
RS23.05.2018
SE23.05.2018
SI23.05.2018
SK23.05.2018
SM23.05.2018
BG23.08.2018
NO23.08.2018
GR24.08.2018
Former [2019/26]AT23.05.2018
CZ23.05.2018
DK23.05.2018
EE23.05.2018
FI23.05.2018
HR23.05.2018
IT23.05.2018
LT23.05.2018
LV23.05.2018
NL23.05.2018
PL23.05.2018
RO23.05.2018
RS23.05.2018
SE23.05.2018
SI23.05.2018
SK23.05.2018
SM23.05.2018
BG23.08.2018
NO23.08.2018
GR24.08.2018
Former [2019/11]AT23.05.2018
CZ23.05.2018
DK23.05.2018
EE23.05.2018
FI23.05.2018
HR23.05.2018
IT23.05.2018
LT23.05.2018
LV23.05.2018
NL23.05.2018
PL23.05.2018
RO23.05.2018
RS23.05.2018
SE23.05.2018
SK23.05.2018
SM23.05.2018
BG23.08.2018
NO23.08.2018
GR24.08.2018
Former [2019/10]AT23.05.2018
CZ23.05.2018
DK23.05.2018
EE23.05.2018
FI23.05.2018
HR23.05.2018
LT23.05.2018
LV23.05.2018
NL23.05.2018
PL23.05.2018
RO23.05.2018
RS23.05.2018
SE23.05.2018
SK23.05.2018
BG23.08.2018
NO23.08.2018
GR24.08.2018
Former [2019/09]DK23.05.2018
EE23.05.2018
FI23.05.2018
HR23.05.2018
LT23.05.2018
LV23.05.2018
NL23.05.2018
RS23.05.2018
SE23.05.2018
BG23.08.2018
NO23.08.2018
GR24.08.2018
Former [2019/08]DK23.05.2018
FI23.05.2018
HR23.05.2018
LT23.05.2018
LV23.05.2018
NL23.05.2018
RS23.05.2018
SE23.05.2018
BG23.08.2018
NO23.08.2018
GR24.08.2018
Former [2018/52]FI23.05.2018
HR23.05.2018
LT23.05.2018
LV23.05.2018
NL23.05.2018
RS23.05.2018
SE23.05.2018
BG23.08.2018
NO23.08.2018
GR24.08.2018
Former [2018/51]FI23.05.2018
HR23.05.2018
LT23.05.2018
LV23.05.2018
RS23.05.2018
SE23.05.2018
BG23.08.2018
NO23.08.2018
Former [2018/50]FI23.05.2018
HR23.05.2018
LT23.05.2018
SE23.05.2018
BG23.08.2018
NO23.08.2018
Former [2018/49]FI23.05.2018
LT23.05.2018
SE23.05.2018
BG23.08.2018
NO23.08.2018
Former [2018/47]FI23.05.2018
LT23.05.2018
NO23.08.2018
Documents cited:Search[X]WO2006134056  (CELLZOME AG [DE], et al) [X] 1-16 * abstract * * page 64; table 9 *;
 [X]  - DEEPA BALASUBRAMANIAM ET AL, "Use of selected reaction monitoring data for label-free quantification of protein modification stoichiometry", PROTEOMICS, DE, (20101102), vol. 10, no. 23, doi:10.1002/pmic.201000232, ISSN 1615-9853, pages 4301 - 4305, XP055180615 [X] 1-16 * abstract * * page 64; table 1 *

DOI:   http://dx.doi.org/10.1002/pmic.201000232
 [X]  - DEEPA BALASUBRAMANIAM ET AL, "Specificity of HCPTP variants toward EphA2 tyrosines by quantitative selected reaction monitoring", PROTEIN SCIENCE, US, (20110523), vol. 20, no. 7, doi:10.1002/pro.646, ISSN 0961-8368, pages 1172 - 1181, XP055180614 [X] 1-16 * abstract *

DOI:   http://dx.doi.org/10.1002/pro.646
International search[Y]US2005049176  (KIENER PETER A [US], et al);
 [Y]US2006121539  (DEBINSKI WALDEMAR [US], et al);
 [A]US2009215098  (CUTILLAS PEDRO RODRIGUEZ [GB], et al);
 [A]US2009226913  (POPE ROBERT M [US], et al);
 [X]US2010098628  (ROHLFF CHRISTIAN [GB], et al);
 [AP]US2011281279  (HAMER PETER [US], et al);
 [A]  - WISSING ET AL., "Proteomics Analysis of Protein Kinases by Target Class-selective Prefractionation and Tandem Mass Spectrometry", MOLECULAR & CELLULAR PROTEOMICS, (2007), vol. 6, no. 3, pages 537 - 547, XP055149300

DOI:   http://dx.doi.org/10.1074/mcp.T600062-MCP200
 [A]  - "Applied Biosystems iTRAQ(tm) Reagents -Amine-Modifying Labeling Reagents for Multiplexed Relative and Absolute Protein Quantification Chemistry Reference Guide.", APPLIED BIOSYSTEMS., (2004), URL: http://proteomics.wayne.edu/pdf/itraq.pdf, XP055148890
 [Y]  - "soluble EPHA2 variant 1 [Homo sapiens]", GENBANK, (20080723), Database accession no. ACF47642, XP003033723
by applicantUS2010098628
 EP1891446
The EPO accepts no responsibility for the accuracy of data originating from other authorities; in particular, it does not guarantee that it is complete, up to date or fit for specific purposes.