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Extract from the Register of European Patents

EP About this file: EP2782993

EP2782993 - METHOD OF IN VITRO FERTILIZATION WITH DELAY OF EMBRYO TRANSFER AND USE OF PERIPHERAL BLOOD MONONUCLEAR CELLS [Right-click to bookmark this link]
StatusExamination is in progress
Status updated on  12.01.2017
Database last updated on 20.07.2024
Most recent event   Tooltip15.11.2023New entry: Renewal fee paid 
Applicant(s)For all designated states
Mezadata Medical IP Holding LLP
111 Buck Road
Unit 550 Suite 1
Huntington Valley, Pennsylvania 19006 / US
[2014/40]
Inventor(s)01 / FESKOV, Alexander
15 Yelizarova Street
Kharkov 61002 / UA
02 / FESKOVA, Irina
15 Yelizarova Street
Kharkov 61002 / UA
03 / ZHYLKOVA, Ievgeniia
20 Frunze Street
Unit 8
Kharkov 61002 / UA
04 / ZHILKOV, Stanislav
301 Byberry Road
Unit D15
Philadelphia Pennsylvania 19116 / US
 [2014/40]
Representative(s)Marks & Clerk LLP
15 Fetter Lane
London EC4A 1BW / GB
[N/P]
Former [2014/40]Hally, Anna-Louise
FRKelly
27 Clyde Road
Dublin 4 / IE
Application number, filing date12851029.421.11.2012
WO2012US66258
Priority number, dateUS201161629651P23.11.2011         Original published format: US 201161629651 P
US20121365525718.10.2012         Original published format: US201213655257
[2014/40]
Filing languageEN
Procedural languageEN
PublicationType: A1 Application with search report
No.:WO2013078312
Date:30.05.2013
Language:EN
[2013/22]
Type: A1 Application with search report 
No.:EP2782993
Date:01.10.2014
Language:EN
The application published by WIPO in one of the EPO official languages on 30.05.2013 takes the place of the publication of the European patent application.
[2014/40]
Search report(s)International search report - published on:US30.05.2013
(Supplementary) European search report - dispatched on:EP18.03.2015
ClassificationIPC:C12N5/078, A61D19/04, A61K35/14, A61B17/435
[2015/16]
CPC:
A61D19/04 (EP,IL,US); A61B17/435 (IL,US); A61D19/00 (EP,IL,US);
A61K35/14 (EP,IL,US); A61K39/461 (EP,IL); A61K39/46431 (EP,IL);
A61P13/00 (EP,IL); A61P15/00 (EP,IL); C12N5/0634 (EP,IL,US);
A61K2035/124 (EP,IL,US); A61K2239/38 (EP,IL); C12N2501/31 (EP,IL,US) (-)
Former IPC [2014/40]C12N5/00
Designated contracting statesAL,   AT,   BE,   BG,   CH,   CY,   CZ,   DE,   DK,   EE,   ES,   FI,   FR,   GB,   GR,   HR,   HU,   IE,   IS,   IT,   LI,   LT,   LU,   LV,   MC,   MK,   MT,   NL,   NO,   PL,   PT,   RO,   RS,   SE,   SI,   SK,   SM,   TR [2014/40]
Extension statesBA23.06.2014
ME23.06.2014
TitleGerman:VERFAHREN ZUR IN-VITRO-FERTILISATION MIT VERZÖGERUNG VON EMBRYONENTRANSFER UND VERWENDUNG VON PERIPHEREN MONONUKLEAREN BLUTZELLEN[2014/40]
English:METHOD OF IN VITRO FERTILIZATION WITH DELAY OF EMBRYO TRANSFER AND USE OF PERIPHERAL BLOOD MONONUCLEAR CELLS[2014/40]
French:METHODE DE FECONDATION IN VITRO AVEC DELAI DU TRANSFERT D'EMBRYON ET UTILISATION DE CELLULES MONONUCLEAIRES DU SANG PERIFERIQUE[2014/40]
Entry into regional phase23.06.2014National basic fee paid 
23.06.2014Search fee paid 
23.06.2014Designation fee(s) paid 
23.06.2014Examination fee paid 
Examination procedure23.06.2014Examination requested  [2014/40]
16.10.2015Amendment by applicant (claims and/or description)
10.06.2016Despatch of a communication from the examining division (Time limit: M06)
17.03.2017Reply to a communication from the examining division
01.08.2017Despatch of a communication from the examining division (Time limit: M06)
24.05.2018Reply to a communication from the examining division
30.10.2018Despatch of a communication from the examining division (Time limit: M06)
06.08.2019Reply to a communication from the examining division
12.05.2020Despatch of a communication from the examining division (Time limit: M06)
15.12.2020Despatch of communication that the application is deemed to be withdrawn, reason: reply to the communication from the examining division not received in time
25.02.2021Reply to a communication from the examining division
21.03.2022Despatch of a communication from the examining division (Time limit: M04)
12.05.2022Reply to a communication from the examining division
08.05.2023Despatch of a communication from the examining division (Time limit: M06)
27.10.2023Reply to a communication from the examining division
Divisional application(s)The date of the Examining Division's first communication in respect of the earliest application for which a communication has been issued is  10.06.2016
Request for further processing for:The application is deemed to be withdrawn due to failure to reply to the examination report
25.02.2021Request for further processing filed
25.02.2021Full payment received (date of receipt of payment)
Request granted
08.03.2021Decision despatched
The application is deemed to be withdrawn due to failure to reply to the examination report
06.08.2019Request for further processing filed
06.08.2019Full payment received (date of receipt of payment)
Request granted
16.08.2019Decision despatched
The application is deemed to be withdrawn due to failure to reply to the examination report
24.05.2018Request for further processing filed
24.05.2018Full payment received (date of receipt of payment)
Request granted
05.06.2018Decision despatched
The application is deemed to be withdrawn due to failure to reply to the examination report
17.03.2017Request for further processing filed
17.03.2017Full payment received (date of receipt of payment)
Request granted
31.03.2017Decision despatched
Fees paidRenewal fee
26.11.2014Renewal fee patent year 03
26.05.2016Renewal fee patent year 04
29.11.2016Renewal fee patent year 05
25.05.2018Renewal fee patent year 06
31.05.2019Renewal fee patent year 07
27.11.2019Renewal fee patent year 08
13.11.2020Renewal fee patent year 09
21.10.2021Renewal fee patent year 10
14.11.2022Renewal fee patent year 11
15.11.2023Renewal fee patent year 12
Penalty fee
Additional fee for renewal fee
30.11.201504   M06   Fee paid on   26.05.2016
30.11.201706   M06   Fee paid on   25.05.2018
30.11.201807   M06   Fee paid on   31.05.2019
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Responsibility for the accuracy, completeness or quality of the data displayed under the link provided lies entirely with the Unified Patent Court.
Documents cited:Search[A]US2005118563  (SHER GEOFFREY [US], et al) [A] 1-15* claims 1-55 *;
 [I]  - S. YOSHIOKA ET AL, "Intrauterine administration of autologous peripheral blood mononuclear cells promotes implantation rates in patients with repeated failure of IVF-embryo transfer", HUMAN REPRODUCTION, (20061201), vol. 21, no. 12, doi:10.1093/humrep/del312, ISSN 0268-1161, pages 3290 - 3294, XP055070108 [I] 1-15 * abstract * * Preparation and intauterine administration of PBMC; page 3291 *

DOI:   http://dx.doi.org/10.1093/humrep/del312
 [I]  - OSAMU OKITSU ET AL, "Intrauterine administration of autologous peripheral blood mononuclear cells increases clinical pregnancy rates in frozen/thawed embryo transfer cycles of patients with repeated implantation failure", JOURNAL OF REPRODUCTIVE IMMUNOLOGY, ELSEVIER SCIENCE IRELAND LTD, IE, vol. 92, no. 1, doi:10.1016/J.JRI.2011.07.001, ISSN 0165-0378, (20110729), pages 82 - 87, (20110824), XP028119151 [I] 1-15 * abstract * * paragraph 2.4; page 84 *

DOI:   http://dx.doi.org/10.1016/j.jri.2011.07.001
 [I]  - IDETA A ET AL, "Administration of peripheral blood mononuclear cells into the uterine horn to improve pregnancy rate following bovine embryo transfer", ANIMAL REPRODUCTION SCIENCE, ELSEVIER SCIENCE PUBLISHERS, AMSTERDAM, NL, vol. 117, no. 1-2, doi:10.1016/J.ANIREPROSCI.2009.04.004, ISSN 0378-4320, (20100101), pages 18 - 23, (20090503), XP026745918 [I] 1-15 * abstract * * paragraph 2.3; page 19 *

DOI:   http://dx.doi.org/10.1016/j.anireprosci.2009.04.004
 [I]  - H. FUJIWARA, "Do circulating blood cells contribute to maternal tissue remodeling and embryo-maternal cross-talk around the implantation period?", MOLECULAR HUMAN REPRODUCTION, (20090403), vol. 15, no. 6, doi:10.1093/molehr/gap027, ISSN 1360-9947, pages 335 - 343, XP055172772 [I] 1-15 * abstract * * page 338, column left *

DOI:   http://dx.doi.org/10.1093/molehr/gap027
 [I]  - L Janský ET AL, "Dynamics of cytokine production in human peripheral blood mononuclear cells stimulated by LPS or infected by Borrelia", Physiological research / Academia Scientiarum Bohemoslovaca, Czech Republic, (20030101), pages 593 - 598, URL: http://www.ncbi.nlm.nih.gov/pubmed/14535835, (20150302), XP055135489 [I] 1-4,6 * Methods; page 594 *
 [I]  - KEISUKE SATO ET AL, "Impact of culture medium on the expansion of T cells for immunotherapy", CYTOTHERAPY, (20090101), vol. 11, no. 7, doi:10.3109/14653240903219114, ISSN 1465-3249, pages 936 - 946, XP055172784 [I] 1-4,6 * abstract * * page 917 * * table 1 *

DOI:   http://dx.doi.org/10.3109/14653240903219114
International search[Y]US2005118563  (SHER GEOFFREY [US], et al);
 [A]US2006015961  (TILLY JONATHAN L [US], et al);
 [X]  - YOSHIOKA ET AL., "Intrauterine administration of autologous peripheral blood mononuclear cells promotes implantation rates in patients with repeated failure of IVF-embryo transfer.", HUMAN REPRODUCTION, vol. 21, no. 12, pages 3290 - 3294, XP055070108

DOI:   http://dx.doi.org/10.1093/humrep/del312
by applicantUS4315908
 US4725579
 US5418159
 WO9905255
 US6605468
 US6838235
 EP1581637
 WO2005121322
 EP1765987
 US7781207
 US7795018
 US7819796
 US8163508
 US8183214
    - YOSHIOKA et al., Human Reproduction, (20061200), vol. 21, no. 12, pages 3290 - 3294
    - OKITSU et al., Journal of Reproductive Immunology, (20110000), vol. 92, no. 1, pages 82 - 87
    - IDETA et al., Animal Reproduction Science, (20100102), vol. 117, pages 18 - 23
    - FUJIWARA, Molecular Human Reproduction, (20090400), vol. 15, no. 6, pages 335 - 343
 WO1998US15124
 US20040777149
 US20040829081
 US20100587406
The EPO accepts no responsibility for the accuracy of data originating from other authorities; in particular, it does not guarantee that it is complete, up to date or fit for specific purposes.