Deutsch English Français

Contact

EP2787990

European procedure

Quick help

Maintenance news

Scheduled maintenance

Regular maintenance outages:
between 05.00 and 05.15 hrs CET (Monday to Sunday).

Other outages
Availability

2022.02.11

More...

News flashes

News Flashes

New version of the European Patent Register – SPC proceedings information in the Unitary Patent Register.

2024-07-24

More...

Extract from the Register of European Patents

EP About this file: EP2787990

EP2787990 - TREATMENT OF AMYLOIDOSIS BY COMPOUNDS THAT REGULATE RETROMER STABILIZATION [Right-click to bookmark this link]
Status	The application is deemed to be withdrawn Status updated on 07.07.2017 Database last updated on 18.11.2024
Former	Examination is in progress Status updated on 02.11.2016
Most recent event Tooltip	07.07.2017	Application deemed to be withdrawn	published on 09.08.2017 [2017/32]
Applicant(s)	For all designated states Brandeis University 415 South Street, MS 115 Waltham, MA 02454 / US
	For all designated states The Trustees Of Columbia University In The City Of New York 535 West 116th Street 412 Low Memorial Library New York, NY 10027 / US
	[N/P]
Former [2014/42]	For all designated states Brandeis University 415 South Street Ms 115 Waltham MA 02454 / US
	For all designated states The Trustees Of Columbia University In The City Of New York 535 West 116th Street 412 Low Memorial Library New York, NY 10027 / US
Inventor(s)	01 / RINGE, Dagmar 983 Memorial Drive Cambridge, MA 02138 / US
	02 / PETSKO, Gregory, A. 8 Jason Road Belmont, MA 02478 / US
	03 / SMALL, Scott A., M.D. 32 Cooper Road Millerton, NY 12546 / US
	04 / MECOZZI, Vincent 604 Tremont Street, No. 4 Boston, Massachusetts 02118 / US
	[2014/42]
Representative(s)	Tostmann, Holger Carl Wallinger Ricker Schlotter Tostmann Patent- und Rechtsanwälte Partnerschaft mbB Zweibrückenstrasse 5-7 80331 München / DE
	[N/P]
Former [2014/42]	Tostmann, Holger Carl Wallinger Ricker Schlotter Tostmann Patent- und Rechtsanwälte Zweibrückenstrasse 5-7 80331 München / DE
Application number, filing date	12854791.6	04.12.2012
	WO2012US67704
Priority number, date	US201161567023P	05.12.2011 Original published format: US 201161567023 P
	[2014/42]
Filing language	EN
Procedural language	EN
Publication	Type:	A1 Application with search report
	No.:	WO2013085877
	Date:	13.06.2013
	Language:	EN
	[2013/24]
	Type:	A1 Application with search report
	No.:	EP2787990
	Date:	15.10.2014
	Language:	EN
	The application published by WIPO in one of the EPO official languages on 13.06.2013 takes the place of the publication of the European patent application.
	[2014/42]
Search report(s)	International search report - published on:	US	13.06.2013
	(Supplementary) European search report - dispatched on:	EP	03.08.2015
Classification	IPC:	A61K31/38, A61K31/195, A61K31/155	[2014/42]
	CPC:	C07D333/18 (EP,US); A61K31/155 (EP,US); A61K31/195 (EP,US); A61K31/38 (EP,US); A61K31/381 (EP,US); A61P25/28 (EP); (+) C07D333/24 (EP,US); C07K14/47 (US) (-)
Designated contracting states	AL, AT, BE, BG, CH, CY, CZ, DE, DK, EE, ES, FI, FR, GB, GR, HR, HU, IE, IS, IT, LI, LT, LU, LV, MC, MK, MT, NL, NO, PL, PT, RO, RS, SE, SI, SK, SM, TR [2014/42]
Title	German:	BEHANDLUNG VON AMYLOIDOSE DURCH VERBINDUNGEN ZUR REGULIERUNG DER RETROMERSTABILISIERUNG	[2014/42]
	English:	TREATMENT OF AMYLOIDOSIS BY COMPOUNDS THAT REGULATE RETROMER STABILIZATION	[2014/42]
	French:	TRAITEMENT DE L'AMYLOÏDOSE AU MOYEN DE COMPOSÉS QUI RÉGULENT LA STABILISATION DE RÉTROMÈRES	[2014/42]
Entry into regional phase	25.06.2014	National basic fee paid
	25.06.2014	Search fee paid
	25.06.2014	Designation fee(s) paid
	25.06.2014	Examination fee paid
Examination procedure	25.06.2014	Examination requested [2014/42]
	29.02.2016	Amendment by applicant (claims and/or description)
	24.10.2016	Despatch of a communication from the examining division (Time limit: M04)
	04.03.2017	Application deemed to be withdrawn, date of legal effect [2017/32]
	31.03.2017	Despatch of communication that the application is deemed to be withdrawn, reason: reply to the communication from the examining division not received in time [2017/32]
Divisional application(s)	The date of the Examining Division's first communication in respect of the earliest application for which a communication has been issued is 24.10.2016
Fees paid	Renewal fee
	29.12.2014	Renewal fee patent year 03
	28.12.2015	Renewal fee patent year 04
	Penalty fee
	Additional fee for renewal fee
	31.12.2016	05 M06 Not yet paid
Opt-out from the exclusive Tooltip competence of the Unified Patent Court	See the Register of the Unified Patent Court for opt-out data
	Responsibility for the accuracy, completeness or quality of the data displayed under the link provided lies entirely with the Unified Patent Court.
Documents cited:	Search	[X]WO2008151288 (XENON PHARMACEUTICALS INC [CA], et al) [X] 1,5-7,9-14 * page 40 * * page 76; example - *;
		[A]US2008214482 (SMALL SCOTT [US], et al) [A] 1-14 * paragraphs [0010] , [0052]; claim - *
		[X] - SUZANNE J. NORWOOD ET AL, "Assembly and Solution Structure of the Core Retromer Protein Complex", TRAFFIC, (20101015), vol. 12, no. 1, doi:10.1111/j.1600-0854.2010.01124.x, ISSN 1398-9219, pages 56 - 71, XP055203031 [X] 2,3 * page 67, column l * DOI: http://dx.doi.org/10.1111/j.1600-0854.2010.01124.x
	International search	[X]US2010240713 (CADIEUX JEAN-JACQUES [CA], et al);
		[A]WO2005046585 (UNIV COLUMBIA [US]);
		[Y] - ZHENG W. ET AL., "Divalent metal transporter 1 is involved in amyloid precursor protein processing and Abeta generation", FASEB J., (200912), vol. 23, pages 4207 - 4217, XP055073393 DOI: http://dx.doi.org/10.1096/fj.09-135749
		[Y] - MEADOWCROFT M. D., "Magnetic Resonance Imaging and Histological Anaylysis of beta-Amyloid Plaques In Human Alzheimer's Disease And APP/PS1 Transgenic Mice", PHD DISSERTATION, (2009), pages I - XX, 1 - 321, URL: etda.libraries.psu.edu, (20130327), XP055076119
		[A] - TABUCHI M. ET AL., "Retromer-mediated direct sorting is required for proper endosomal recycling of the mammalian iron transporter DMT1", J CELL SCI., (2010), vol. 123, pages 756 - 766, XP055076123 DOI: http://dx.doi.org/10.1242/jcs.060574
		[A] - MCGOUGH I.J. ET AL., "Recent Advances in Retromer Biology", TRAFFIC, (201105), vol. 12, pages 963 - 971, XP055076126 DOI: http://dx.doi.org/10.1111/j.1600-0854.2011.01201.x
		[A] - HIERRO A. ET AL., "Functional architecture of the retromer cargo-recognition complex", NATURE, (2007), vol. 449, no. 7165, pages 1063 - 1067, XP055076131 DOI: http://dx.doi.org/10.1038/nature06216
		[A] - ZIMPRICH A. ET AL., "A mutation in VPS35, encoding a subunit of the retromer complex, causes late-onset Parkinson disease", AM J HUM GENET., (20110715), vol. 89, pages 168 - 175, XP028239045 DOI: http://dx.doi.org/10.1016/j.ajhg.2011.06.008
		[A] - LI WAN ET AL., "beta-Amyloid peptide increases levels of iron content and oxidative stress in human cell and Caenorhabditis elegans models of Alzheimer disease", FREE RADIC BIOL MED., (201101), vol. 50, no. 1, pages 122 - 129, XP027576844
		[A] - KENCHE V.B. ET AL., "Alzheimer's disease & metals: therapeutic opportunities", BR J PHARMACOL., (201105), vol. 163, no. 2, pages 211 - 219, XP055076133 DOI: http://dx.doi.org/10.1111/j.1476-5381.2011.01221.x

The EPO accepts no responsibility for the accuracy of data originating from other authorities; in particular, it does not guarantee that it is complete, up to date or fit for specific purposes.

Legal notice
Terms of use
24.2.25; 34p