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EP2799537
European procedure
Extract from the Register of European Patents
EP About this file: EP2799537
| EP2799537 - NORMALIZATION OF CULTURE OF CORNEAL ENDOTHELIAL CELLS [Right-click to bookmark this link] | Status | No opposition filed within time limit Status updated on 29.07.2022 Database last updated on 17.07.2024 | |
| Former | The patent has been granted Status updated on 20.08.2021 | ||
| Former | Grant of patent is intended Status updated on 22.06.2021 | ||
| Former | Examination is in progress Status updated on 17.03.2021 | ||
| Former | Grant of patent is intended Status updated on 11.02.2021 | ||
| Former | Examination is in progress Status updated on 23.12.2020 | ||
| Former | Grant of patent is intended Status updated on 20.12.2020 | ||
| Former | Examination is in progress Status updated on 30.11.2020 | ||
| Former | Grant of patent is intended Status updated on 23.11.2020 | ||
| Former | Examination is in progress Status updated on 10.04.2020 | ||
| Former | Grant of patent is intended Status updated on 11.12.2019 | ||
| Former | Examination is in progress Status updated on 28.04.2017 | Most recent event Tooltip | 27.04.2024 | Lapse of the patent in a contracting state New state(s): MK | published on 29.05.2024 [2024/22] | Applicant(s) | For all designated states Kyoto Prefectural Public University Corporation 465 Kajii-cho Kawaramachi-dori, Hirokoji-agaru Kamigyo-ku Kyoto-shi Kyoto 602-8566 / JP | For all designated states ActualEyes Inc. 1-D-egg 314 Jizodani Kodo Kyotanabe-city, Kyoto / JP | For all designated states CorneaGen, Inc. 1200 6th Ave., Ste. 300 Seattle, WA 98101 / US | [2020/37] |
| Former [2020/36] | For all designated states Kyoto Prefectural Public University Corporation 465 Kajii-cho Kawaramachi-dori, Hirokoji-agaru Kamigyo-ku Kyoto-shi Kyoto 602-8566 / JP | ||
| For all designated states ActualEyes Inc. 1-D-egg 314 Jizodani Kondo Kyotanabe-city, Kyoto / JP | |||
| Former [2019/03] | For all designated states Kyoto Prefectural Public University Corporation 465 Kajii-cho Kawaramachi-dori, Hirokoji-agaru Kamigyo-ku Kyoto-shi Kyoto 602-8566 / JP | ||
| For all designated states The Doshisha 601, Gembu-cho Karasuma-higashi-iru Imadegawa-dori Kamigyo-ku, Kyoto-shi Kyoto 602-8580 / JP | |||
| For all designated states Senju Pharmaceutical Co., Ltd. 3-1-9, Kawara-machi Chuo-ku Osaka-shi Osaka 541-0048 / JP | |||
| Former [2014/45] | For all designated states Kyoto Prefectural Public University Corporation 465 Kajii-cho Kawaramachi-dori, Hirokoji-agaru Kamigyo-ku Kyoto-shi Kyoto 602-8566 / JP | ||
| For all designated states The Doshisha 601, Gembu-cho Karasuma-higashi-iru Imadegawa-dori Kamigyo-ku, Kyoto-shi Kyoto 602-8580 / JP | |||
| For all designated states Senju Pharmaceutical Co., Ltd. 5-8, Hiranomachi 2-chome Chuo-Ku Osaka-shi, Osaka 541-0046 / JP | Inventor(s) | 01 /
KINOSHITA, Shigeru c/o Kyoto Prefectural Public University corporation 465 Kajii-cho Hirokoji-agaru Kawaramachi-dori, Kamigyo-ku Kyoto-shi Kyoto 602-8566 / JP | 02 /
KOIZUMI, Noriko c/o Doshisha University 1-3 Tatara Miyakodani Kyotanabe-shi Kyoto 610-0394 / JP | 03 /
OKUMURA, Naoki c/o Doshisha University 1-3 Tatara Miyakodani Kyotanabe-shi Kyoto 610-0394 / JP | [2014/45] | Representative(s) | Engelhard, Markus Boehmert & Boehmert Anwaltspartnerschaft mbB Pettenkoferstrasse 22 80336 München / DE | [2021/38] |
| Former [2014/45] | Engelhard, Markus Boehmert & Boehmert Anwaltspartnerschaft mbB Patentanwälte Rechtsanwälte Pettenkoferstrasse 20-22 80336 München / DE | Application number, filing date | 12862290.9 | 27.12.2012 | [2021/38] | WO2012JP84320 | Priority number, date | JP20110289666 | 28.12.2011 Original published format: JP 2011289666 | JP20120030969 | 15.02.2012 Original published format: JP 2012030969 | JP20120151340 | 05.07.2012 Original published format: JP 2012151340 | [2014/45] | Filing language | JA | Procedural language | EN | Publication | Type: | A1 Application with search report | No.: | WO2013100208 | Date: | 04.07.2013 | Language: | JA | [2013/27] | Type: | A1 Application with search report | No.: | EP2799537 | Date: | 05.11.2014 | Language: | EN | [2014/45] | Type: | B1 Patent specification | No.: | EP2799537 | Date: | 22.09.2021 | Language: | EN | [2021/38] | Search report(s) | International search report - published on: | JP | 04.07.2013 | (Supplementary) European search report - dispatched on: | EP | 27.11.2015 | Classification | IPC: | C12N5/079, A61K9/70, A61K31/4409, A61K31/4418, A61K31/4439, A61K31/4709, A61K31/519, A61K31/713, A61K35/30, A01N1/02, A61P43/00 | [2019/41] | CPC: |
A61K35/30 (EP,US);
A01N1/0226 (EP,US);
A61K31/4409 (EP,US);
A61K31/4439 (EP,US);
A61K31/4709 (EP,US);
A61K31/519 (EP,US);
A61K31/713 (EP,US);
A61P27/02 (EP);
A61P43/00 (EP);
C07K16/22 (US);
C12N5/0602 (US);
C12N5/0621 (EP,US);
C12N2500/14 (EP,US);
C12N2500/38 (EP,US);
C12N2501/11 (EP,US);
C12N2501/15 (EP,US);
C12N2501/155 (EP,US);
C12N2501/727 (EP,US);
|
| Former IPC [2014/45] | C12N5/071, A61K9/70, A61K31/4418, A61K35/12, A61L27/00, A61P27/02, A61P43/00, C12N15/09 | Designated contracting states | AL, AT, BE, BG, CH, CY, CZ, DE, DK, EE, ES, FI, FR, GB, GR, HR, HU, IE, IS, IT, LI, LT, LU, LV, MC, MK, MT, NL, NO, PL, PT, RO, RS, SE, SI, SK, SM, TR [2014/45] | Extension states | BA | Not yet paid | ME | Not yet paid | Title | German: | NORMALISIERUNG DER ZÜCHTUNG VON HORNHAUTENDOTHELZELLEN | [2014/45] | English: | NORMALIZATION OF CULTURE OF CORNEAL ENDOTHELIAL CELLS | [2014/45] | French: | NORMALISATION D'UNE CULTURE DE CELLULES ENDOTHÉLIALES DE LA CORNÉE | [2014/45] | Entry into regional phase | 25.07.2014 | Translation filed | 25.07.2014 | National basic fee paid | 25.07.2014 | Search fee paid | 25.07.2014 | Designation fee(s) paid | 25.07.2014 | Examination fee paid | Examination procedure | 25.07.2014 | Examination requested [2014/45] | 09.06.2016 | Amendment by applicant (claims and/or description) | 28.04.2017 | Despatch of a communication from the examining division (Time limit: M06) | 24.10.2017 | Reply to a communication from the examining division | 01.06.2018 | Despatch of a communication from the examining division (Time limit: M06) | 30.11.2018 | Reply to a communication from the examining division | 12.12.2019 | Communication of intention to grant the patent | 08.04.2020 | Disapproval of the communication of intention to grant the patent by the applicant or resumption of examination proceedings by the EPO | 07.05.2020 | Despatch of a communication from the examining division (Time limit: M02) | 06.07.2020 | Reply to a communication from the examining division | 23.06.2021 | Communication of intention to grant the patent | 13.08.2021 | Fee for grant paid | 13.08.2021 | Fee for publishing/printing paid | 13.08.2021 | Receipt of the translation of the claim(s) | Divisional application(s) | EP19172604.1 / EP3553169 | The date of the Examining Division's first communication in respect of the earliest application for which a communication has been issued is 28.04.2017 | Opposition(s) | 23.06.2022 | No opposition filed within time limit [2022/35] | Fees paid | Renewal fee | 11.12.2014 | Renewal fee patent year 03 | 10.12.2015 | Renewal fee patent year 04 | 13.12.2016 | Renewal fee patent year 05 | 15.12.2017 | Renewal fee patent year 06 | 12.12.2018 | Renewal fee patent year 07 | 27.12.2019 | Renewal fee patent year 08 | 14.12.2020 | Renewal fee patent year 09 |
| Opt-out from the exclusive Tooltip competence of the Unified Patent Court | See the Register of the Unified Patent Court for opt-out data | ||
| Responsibility for the accuracy, completeness or quality of the data displayed under the link provided lies entirely with the Unified Patent Court. | Lapses during opposition Tooltip | HU | 27.12.2012 | AL | 22.09.2021 | AT | 22.09.2021 | CY | 22.09.2021 | CZ | 22.09.2021 | DK | 22.09.2021 | EE | 22.09.2021 | FI | 22.09.2021 | HR | 22.09.2021 | LT | 22.09.2021 | LV | 22.09.2021 | MC | 22.09.2021 | MK | 22.09.2021 | NL | 22.09.2021 | PL | 22.09.2021 | RO | 22.09.2021 | RS | 22.09.2021 | SE | 22.09.2021 | SI | 22.09.2021 | SK | 22.09.2021 | SM | 22.09.2021 | BG | 22.12.2021 | NO | 22.12.2021 | GR | 23.12.2021 | IE | 27.12.2021 | LU | 27.12.2021 | BE | 31.12.2021 | CH | 31.12.2021 | LI | 31.12.2021 | IS | 22.01.2022 | PT | 24.01.2022 | [2024/22] |
| Former [2023/33] | HU | 27.12.2012 | |
| AL | 22.09.2021 | ||
| AT | 22.09.2021 | ||
| CY | 22.09.2021 | ||
| CZ | 22.09.2021 | ||
| DK | 22.09.2021 | ||
| EE | 22.09.2021 | ||
| FI | 22.09.2021 | ||
| HR | 22.09.2021 | ||
| LT | 22.09.2021 | ||
| LV | 22.09.2021 | ||
| MC | 22.09.2021 | ||
| NL | 22.09.2021 | ||
| PL | 22.09.2021 | ||
| RO | 22.09.2021 | ||
| RS | 22.09.2021 | ||
| SE | 22.09.2021 | ||
| SI | 22.09.2021 | ||
| SK | 22.09.2021 | ||
| SM | 22.09.2021 | ||
| BG | 22.12.2021 | ||
| NO | 22.12.2021 | ||
| GR | 23.12.2021 | ||
| IE | 27.12.2021 | ||
| LU | 27.12.2021 | ||
| BE | 31.12.2021 | ||
| CH | 31.12.2021 | ||
| LI | 31.12.2021 | ||
| IS | 22.01.2022 | ||
| PT | 24.01.2022 | ||
| Former [2023/30] | HU | 27.12.2012 | |
| AL | 22.09.2021 | ||
| AT | 22.09.2021 | ||
| CY | 22.09.2021 | ||
| CZ | 22.09.2021 | ||
| DK | 22.09.2021 | ||
| EE | 22.09.2021 | ||
| FI | 22.09.2021 | ||
| HR | 22.09.2021 | ||
| LT | 22.09.2021 | ||
| LV | 22.09.2021 | ||
| MC | 22.09.2021 | ||
| NL | 22.09.2021 | ||
| PL | 22.09.2021 | ||
| RO | 22.09.2021 | ||
| RS | 22.09.2021 | ||
| SE | 22.09.2021 | ||
| SI | 22.09.2021 | ||
| SK | 22.09.2021 | ||
| BG | 22.12.2021 | ||
| NO | 22.12.2021 | ||
| GR | 23.12.2021 | ||
| IE | 27.12.2021 | ||
| LU | 27.12.2021 | ||
| BE | 31.12.2021 | ||
| CH | 31.12.2021 | ||
| LI | 31.12.2021 | ||
| IS | 22.01.2022 | ||
| PT | 24.01.2022 | ||
| Former [2023/29] | HU | 27.12.2012 | |
| AL | 22.09.2021 | ||
| AT | 22.09.2021 | ||
| CZ | 22.09.2021 | ||
| DK | 22.09.2021 | ||
| EE | 22.09.2021 | ||
| FI | 22.09.2021 | ||
| HR | 22.09.2021 | ||
| LT | 22.09.2021 | ||
| LV | 22.09.2021 | ||
| MC | 22.09.2021 | ||
| NL | 22.09.2021 | ||
| PL | 22.09.2021 | ||
| RO | 22.09.2021 | ||
| RS | 22.09.2021 | ||
| SE | 22.09.2021 | ||
| SI | 22.09.2021 | ||
| SK | 22.09.2021 | ||
| BG | 22.12.2021 | ||
| NO | 22.12.2021 | ||
| GR | 23.12.2021 | ||
| IE | 27.12.2021 | ||
| LU | 27.12.2021 | ||
| BE | 31.12.2021 | ||
| CH | 31.12.2021 | ||
| LI | 31.12.2021 | ||
| IS | 22.01.2022 | ||
| PT | 24.01.2022 | ||
| Former [2023/03] | AL | 22.09.2021 | |
| AT | 22.09.2021 | ||
| CZ | 22.09.2021 | ||
| DK | 22.09.2021 | ||
| EE | 22.09.2021 | ||
| FI | 22.09.2021 | ||
| HR | 22.09.2021 | ||
| LT | 22.09.2021 | ||
| LV | 22.09.2021 | ||
| MC | 22.09.2021 | ||
| NL | 22.09.2021 | ||
| PL | 22.09.2021 | ||
| RO | 22.09.2021 | ||
| RS | 22.09.2021 | ||
| SE | 22.09.2021 | ||
| SI | 22.09.2021 | ||
| SK | 22.09.2021 | ||
| BG | 22.12.2021 | ||
| NO | 22.12.2021 | ||
| GR | 23.12.2021 | ||
| IE | 27.12.2021 | ||
| LU | 27.12.2021 | ||
| BE | 31.12.2021 | ||
| CH | 31.12.2021 | ||
| LI | 31.12.2021 | ||
| IS | 22.01.2022 | ||
| PT | 24.01.2022 | ||
| Former [2023/01] | AL | 22.09.2021 | |
| AT | 22.09.2021 | ||
| CZ | 22.09.2021 | ||
| DK | 22.09.2021 | ||
| EE | 22.09.2021 | ||
| FI | 22.09.2021 | ||
| HR | 22.09.2021 | ||
| LT | 22.09.2021 | ||
| LV | 22.09.2021 | ||
| MC | 22.09.2021 | ||
| NL | 22.09.2021 | ||
| PL | 22.09.2021 | ||
| RO | 22.09.2021 | ||
| RS | 22.09.2021 | ||
| SE | 22.09.2021 | ||
| SI | 22.09.2021 | ||
| SK | 22.09.2021 | ||
| BG | 22.12.2021 | ||
| NO | 22.12.2021 | ||
| GR | 23.12.2021 | ||
| IE | 27.12.2021 | ||
| LU | 27.12.2021 | ||
| BE | 31.12.2021 | ||
| IS | 22.01.2022 | ||
| PT | 24.01.2022 | ||
| Former [2022/48] | AL | 22.09.2021 | |
| AT | 22.09.2021 | ||
| CZ | 22.09.2021 | ||
| DK | 22.09.2021 | ||
| EE | 22.09.2021 | ||
| FI | 22.09.2021 | ||
| HR | 22.09.2021 | ||
| LT | 22.09.2021 | ||
| LV | 22.09.2021 | ||
| MC | 22.09.2021 | ||
| NL | 22.09.2021 | ||
| PL | 22.09.2021 | ||
| RO | 22.09.2021 | ||
| RS | 22.09.2021 | ||
| SE | 22.09.2021 | ||
| SK | 22.09.2021 | ||
| BG | 22.12.2021 | ||
| NO | 22.12.2021 | ||
| GR | 23.12.2021 | ||
| IE | 27.12.2021 | ||
| LU | 27.12.2021 | ||
| IS | 22.01.2022 | ||
| PT | 24.01.2022 | ||
| Former [2022/46] | AL | 22.09.2021 | |
| AT | 22.09.2021 | ||
| CZ | 22.09.2021 | ||
| DK | 22.09.2021 | ||
| EE | 22.09.2021 | ||
| FI | 22.09.2021 | ||
| HR | 22.09.2021 | ||
| LT | 22.09.2021 | ||
| LV | 22.09.2021 | ||
| MC | 22.09.2021 | ||
| NL | 22.09.2021 | ||
| PL | 22.09.2021 | ||
| RO | 22.09.2021 | ||
| RS | 22.09.2021 | ||
| SE | 22.09.2021 | ||
| SK | 22.09.2021 | ||
| BG | 22.12.2021 | ||
| NO | 22.12.2021 | ||
| GR | 23.12.2021 | ||
| LU | 27.12.2021 | ||
| IS | 22.01.2022 | ||
| PT | 24.01.2022 | ||
| Former [2022/36] | AL | 22.09.2021 | |
| AT | 22.09.2021 | ||
| CZ | 22.09.2021 | ||
| DK | 22.09.2021 | ||
| EE | 22.09.2021 | ||
| FI | 22.09.2021 | ||
| HR | 22.09.2021 | ||
| LT | 22.09.2021 | ||
| LV | 22.09.2021 | ||
| MC | 22.09.2021 | ||
| NL | 22.09.2021 | ||
| PL | 22.09.2021 | ||
| RO | 22.09.2021 | ||
| RS | 22.09.2021 | ||
| SE | 22.09.2021 | ||
| SK | 22.09.2021 | ||
| BG | 22.12.2021 | ||
| NO | 22.12.2021 | ||
| GR | 23.12.2021 | ||
| IS | 22.01.2022 | ||
| PT | 24.01.2022 | ||
| Former [2022/33] | AL | 22.09.2021 | |
| AT | 22.09.2021 | ||
| CZ | 22.09.2021 | ||
| EE | 22.09.2021 | ||
| FI | 22.09.2021 | ||
| HR | 22.09.2021 | ||
| LT | 22.09.2021 | ||
| LV | 22.09.2021 | ||
| MC | 22.09.2021 | ||
| NL | 22.09.2021 | ||
| PL | 22.09.2021 | ||
| RO | 22.09.2021 | ||
| RS | 22.09.2021 | ||
| SE | 22.09.2021 | ||
| SK | 22.09.2021 | ||
| BG | 22.12.2021 | ||
| NO | 22.12.2021 | ||
| GR | 23.12.2021 | ||
| IS | 22.01.2022 | ||
| PT | 24.01.2022 | ||
| Former [2022/29] | AL | 22.09.2021 | |
| AT | 22.09.2021 | ||
| CZ | 22.09.2021 | ||
| EE | 22.09.2021 | ||
| FI | 22.09.2021 | ||
| HR | 22.09.2021 | ||
| LT | 22.09.2021 | ||
| LV | 22.09.2021 | ||
| NL | 22.09.2021 | ||
| PL | 22.09.2021 | ||
| RO | 22.09.2021 | ||
| RS | 22.09.2021 | ||
| SE | 22.09.2021 | ||
| SK | 22.09.2021 | ||
| BG | 22.12.2021 | ||
| NO | 22.12.2021 | ||
| GR | 23.12.2021 | ||
| IS | 22.01.2022 | ||
| PT | 24.01.2022 | ||
| Former [2022/24] | AT | 22.09.2021 | |
| CZ | 22.09.2021 | ||
| EE | 22.09.2021 | ||
| FI | 22.09.2021 | ||
| HR | 22.09.2021 | ||
| LT | 22.09.2021 | ||
| LV | 22.09.2021 | ||
| NL | 22.09.2021 | ||
| PL | 22.09.2021 | ||
| RO | 22.09.2021 | ||
| RS | 22.09.2021 | ||
| SE | 22.09.2021 | ||
| SK | 22.09.2021 | ||
| BG | 22.12.2021 | ||
| NO | 22.12.2021 | ||
| GR | 23.12.2021 | ||
| IS | 22.01.2022 | ||
| PT | 24.01.2022 | ||
| Former [2022/23] | AT | 22.09.2021 | |
| CZ | 22.09.2021 | ||
| EE | 22.09.2021 | ||
| FI | 22.09.2021 | ||
| HR | 22.09.2021 | ||
| LT | 22.09.2021 | ||
| LV | 22.09.2021 | ||
| PL | 22.09.2021 | ||
| RS | 22.09.2021 | ||
| SE | 22.09.2021 | ||
| SK | 22.09.2021 | ||
| BG | 22.12.2021 | ||
| NO | 22.12.2021 | ||
| GR | 23.12.2021 | ||
| PT | 24.01.2022 | ||
| Former [2022/21] | AT | 22.09.2021 | |
| FI | 22.09.2021 | ||
| HR | 22.09.2021 | ||
| LT | 22.09.2021 | ||
| LV | 22.09.2021 | ||
| RS | 22.09.2021 | ||
| SE | 22.09.2021 | ||
| BG | 22.12.2021 | ||
| NO | 22.12.2021 | ||
| GR | 23.12.2021 | ||
| Former [2022/10] | FI | 22.09.2021 | |
| HR | 22.09.2021 | ||
| LT | 22.09.2021 | ||
| LV | 22.09.2021 | ||
| RS | 22.09.2021 | ||
| SE | 22.09.2021 | ||
| BG | 22.12.2021 | ||
| NO | 22.12.2021 | ||
| GR | 23.12.2021 | ||
| Former [2022/09] | FI | 22.09.2021 | |
| LT | 22.09.2021 | ||
| RS | 22.09.2021 | ||
| SE | 22.09.2021 | ||
| BG | 22.12.2021 | ||
| NO | 22.12.2021 | ||
| Former [2022/08] | FI | 22.09.2021 | |
| LT | 22.09.2021 | ||
| SE | 22.09.2021 | ||
| BG | 22.12.2021 | ||
| NO | 22.12.2021 | ||
| Former [2022/07] | LT | 22.09.2021 | |
| NO | 22.12.2021 | Documents cited: | Search | [XD]US2006234911 (HOFFMANN F M [US], et al) [XD] 1-13,16 * example - *; | [X]EP1726639 (YAMAGAMI SATORU [JP], et al) [X] 15,17,18 * the whole document *; | [A]EP2193806 (SENJU PHARMA CO [JP], et al) [A] 9,19; | [T] - OKUMURA N ET AL, "Inhibition of TGF-[beta] Signaling Enables Human Corneal Endothelial Cell Expansion In Vitro for Use in Regenerative Medicine", PLOS ONE, (20130225), vol. 8, no. 2, doi:10.1371/journal.pone.0058000, page e58000, XP055229718 DOI: http://dx.doi.org/10.1371/journal.pone.0058000 | [T] - OKUMURA N ET AL, "Cell-based approach for treatment of corneal endothelial dysfunction", CORNEA, (201411), vol. 33, no. Suppl. 11, doi:10.1097/ICO.0000000000000229, ISSN 1536-4798, pages S37 - S41, XP008178140 DOI: http://dx.doi.org/10.1097/ICO.0000000000000229 | International search | [A]WO2005038015 (LIU GE MING [US], et al); | [X] - FUNAKI T. 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